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1941 articles for “Methods” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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A Comprehensive Review of Analytical Method – Development and Method Validation of Digoxin Tablets
Abstract: The main objective of this review is to give an outline of the method development and validation process of digoxin, and this review covers the different types of spectroscopic and chromatographic techniques, such as HPLC, UHPLC-Tandem mass spectroscopy, TLC, and LC-MS. A novel method for the determination of digoxin in biological samples has been developed and validated, focusing on improving sensitivity, specificity, and reproducibility. The method was validated in terms …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 47–58 Read article
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Modelling of The Viscoelastic Composite Curved Panel for The Time Domain Analysis Using TTBDF, β1 / β2−Bathe and Newmark Method
Abstract: Viscoelastic materials are extensively used in structures, especially thin-walled structures, for damping. The accurate modelling of the time domain dynamics of the viscoelastic material is essential for appropriately capturing the damping of the viscoelastic material. Various implicit and explicit time integration schemes are available to evaluate time domain response. However, the rightness of the implementation of the time integration scheme to the viscoelastic material model is very essential. In this …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 204–222 Read article
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Analytical Method Development and Validation of Simultaneous Estimation of Natural Active Constituents Andrographolide and Piperine by UV Method.
Abstract: A simple, accurate, precise, and robust UV-Visible spectrophotometric method was developed and validated for the simultaneous estimation of Andrographolide and Piperine in bulk and combined pharmaceutical dosage forms. Preformulation studies confirmed favorable physicochemical properties for both drugs, including acceptable solubility profiles, melting points, pH values, and partition coefficients. The method development involved determination of λmax values at 224 nm for Andrographolide and 288 nm for Piperine using ethanol as solvent. …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 33–41 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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HPTLC Method Development and Validation for Rabeprazole Sodium in Pharmaceutical Formulation
Abstract: Background: The most common medication for acid related disorders stands as Proton pump inhibitor (PPI) Rabeprazole Sodium. The pharmaceutical formulations require essential quality control of Rabeprazole Sodium through reliable analytical methods to maintain reliability. HPTLC provides a cost-effective rapid method for drug quantification compared to conventional HPLC methods so how HPTLC stands as an appropriate method for drug determination. Objective: The emphasis of this research project involves developing and validating …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 18–24 Read article
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Analytical Method Development and Validation for Simultaneous Estimation of Paracetamol and Piroxicam by UV Method
Abstract: A new establishment and validation of a simple, precise, accurate and cost effective UV-Visible spectrophotometric method was developed to estimate both Paracetamol and Piroxicam simultaneously in conjoined pharmaceutical dosage forms. This technique was founded on simultaneous equation method of absorbances recorded at 252.0 nm and 282.0 nm of Paracetamol and Piroxicam in methanol respectively and an isosbestic point could be observed at 265.0 nm. It showed very good linearity over …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 14–21 Read article
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Solving Optimization Problems Using the Graphical Method of Linear Programming
Abstract: Linear programming is a mathematical optimization technique used for maximizing or minimizing a linear objective function while satisfying a set of linear constraints. This method plays a crucial role in various industries, including manufacturing, finance, transportation, and supply chain management. Among the different approaches to solving linear programming problems, the graphical method provides a simple and intuitive way to visualize and solve problems involving two decision variables. By plotting constraints …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 2, 2025 · pp. 01–08 Read article
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A Systematic Review of Method Development and Validation for Ramipril Analysis Using Hplc in Cardiovascular Research
Abstract: The field of analytical chemistry encompasses a variety of methods that are crucial in determining the chemical composition of different substances. UV-visible spectroscopy and high-performance liquid chromatography (HPLC) are two widely utilized methods that are the subject of this article. UV-visible spectroscopy uses the Beer-Lambert law to quantify light absorption, which can provide information about the concentration of absorbing species. The method is based on how light and matter interact, …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 2, 2024 · pp. 37–44 Read article
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A Review of Analytical Method Development and Validation of Amiodarone Pharmaceutical Dosage Form
Abstract: The review provides an in-depth analysis of the analytical method development and validation process for amiodarone tablets. Method validation is crucial in the pharmaceutical industry for ensuring the quality and efficacy of tablets, as it ensures the accuracy, precision, and reliability of analytical techniques used in drug testing. It is a prerequisite for method development, adhering to good manufacturing practices, and optimizing processes. This review aims to consolidate and analyse …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 59–71 Read article
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Analysis of Field Distribution in Optical Fibre Using FEM Method
Abstract: The application of the linear Finite Element Method (FEM) to the analysis of the field distribution in optical fibres is examined in this work. Characterizing fibre characteristics like mode profiles, propagation constants, and dispersion, all of which are critical for maximizing fibre performance in a variety of applications like sensing and telecommunications, requires an understanding of the distribution of electric and magnetic fields. In order to accurately determine the modal …
Published in Trends in Opto-electro & Optical Communication · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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A Novel Direct Weighted Deviation (DWD) Method for Agricultural Enterprise Selection: A Case Study of Namakkal District, Tamil Nadu
Abstract: The study proposes a novel Direct Weighted Deviation (DWD) method for Multi-Criteria Decision Making (MCDM) by eliminating normalization, distance metrics, and pairwise comparisons. DWD is thereafter used to evaluate and select ten rainfed agricultural enterprises against ten generic and context-specific viability criteria in Namakkal District, Tamil Nadu, a water-scarce region in India. Subsequently, other methods (AHP, SAW, WPM, and TOPSIS) are used to obtain a comparative second opinion and validate …
Published in International Journal of Industrial and Product Design Engineering · Vol. 4, Issue 1, 2026 · pp. 1–7 Read article
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Development and Validation of a Robust RP-HPLC Method for Rufinamide Quantification in Pharmaceutical Dosage Forms
Abstract: The creation and validation of a simple, precise, and targeted reverse phase high-performance liquid chromatographic (RP-HPLC) approach allowed for the quantification of rufinamide in pharmaceutical dosage forms. With a mobile phase of methanol and water (50:50, v/v), the technique used a gradient mode Symmetry Qualisil gold C18 column (4.6 x 150mm, 5 μm). For the detection method, a flow rate of 1 mL/min was employed at 220 nm. During a …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 25–32 Read article
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Research on Selection Method of the Optimum Alternative Using Improved AHP Method in NSDL Environment
Abstract: In this paper, we have considered the development of a decision-making tool to optimize the design of the ship-roll fin stabilizer using improved analytical hierarchy process (AHP) in a network-oriented system description language (NSDL) environment developed by combining the advantages of Petri nets and object-oriented programming languages. First, we have considered the network-oriented system description language NSDL, a new software development tool that combines the advantages of Petri nets and …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 3, Issue 1, 2025 · pp. 46–56 Read article
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Study on the Method of Calculation of the Additional Mass of Parachute
Abstract: As is well known, the air drag experienced by a parachute when it is open is one of the important parameters that must be taken into account in studying the parachute opening process. If this term is not calculated correctly, it can have a negative effect on the parachute canopy, and may lead to errors in the number of parachute strings, the nominal diameter of the parachute, and the material …
Published in International Journal of Machine Systems and Manufacturing Technology · Vol. 3, Issue 2, 2025 · pp. 22–31 Read article
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A Shear Strength Reduction Method for an Open Pit Slope Stability Analysis Based on Finite Element Method
Abstract: Slope stability assessment of open pit mines is critically important, since it forms part of the overall productivity and safety management strategy of the mines. The aim of this work is to investigate the overall stability conditions of three (3) open pits in Gold Fields Limited, Tarkwa Ghana. Field and laboratory investigations were conducted as well as empirical methods. Finite Element Analysis (FEA) in Rocscience was carried out using the …
Published in Journal of Geotechnical Engineering · Vol. 13, Issue 1, 2026 · pp. 1–24 Read article
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Comparative Study of Structural and Optical Properties of Bismuth Ferrite Nanoparticles for Photovoltaic Applications Synthesized via Different Sol-Gel Methods
Abstract: Pure multiferroic bismuth ferrite (BiFeO3) nanoparticles were successfully synthesized using an energy-efficient, low-temperature sol-gel method, comparing two distinct approaches: auto-combustion and non-auto-combustion. To ensure phase stability, the precursor solution's pH was strictly maintained between 1 and 2 using ammonia solution (NH4OH), while ethylene glycol (C2H6O2) was employed as a chelating agent for the Fe3+ and Bi3+ cations. All samples underwent a final annealing process at 500 °C to promote crystallization. …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 83–94 Read article
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An Open Labelled Parallel Arm Randomized Clinical Trial of Tuvaraka Oil Prepared By Two Different Method In The Management of Pama
Abstract: In Ayurveda, all skin diseases have classified mainly into two groups i.e., Mahakushtha (major skin diseases) and Kshudrakushtha (minor skin diseases). Tuvaraka [Hydnocarpus laurifolia (Dessnt).Sleumer] is one among the most useful drugs for the treatment of Kushtha (Various skin diseases) and Madhumeha (Diabetes Melitus). Pama is described under Kshudra Kushtha. which can be correlates with scabies. Aim: To evaluate the clinical efficacy of Tuvaraka oil prepared by modified method and …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 29–36 Read article
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Estimating Heavy Ion Concentrations in the Shatt AlKufa Area and Studying Methods for Recycling Wastewater
Abstract: This study includes practical methods for treating chemical pollution in wastewater. The proper disposal of wastewater is essential for providing a healthy environment for communities, adhering to international standards and utilizing the latest chemical and scientific methods to maintain a surrounding environment free from sewage pollutants. The goal of wastewater treatment is to prepare it for discharge into agricultural drains or for use in irrigation. Treatment removes a large percentage …
Published in Journal of Catalyst & Catalysis · Vol. 13, Issue 1, 2026 · pp. 17–22 Read article
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A Novel Symmetric Anchor Scoring (SAS) Method for Industrial Location Selection: Application to Electric Vehicle Manufacturing in Tamil Nadu, India
Abstract: This work highlights the city-level detail of decision-making enabled by a new MCDM method Symmetry Anchor Scoring (SAS). Generally conventional methods are good at selecting one best and one worst alternative, but not differentiating among the many strong contenders more likely in practice. Linking MCDM methods to the tradition of decision making, the paper discusses the mathematics and analogical basis of SAS design, provides a visual proof of its ideal …
Published in International Journal of Industrial and Product Design Engineering · Vol. 4, Issue 1, 2026 · pp. 8–19 Read article
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Comprehensive Overview of Analytical Chemistry: Principles, Techniques, and Method Validation
Abstract: Analytical chemistry constitutes a vital discipline within the realm of scientific inquiry, facilitating the identification and measurement of components present in diverse substances and mixtures. This paper delineates the principles, methodologies, and applications of analytical chemistry, focusing on spectroscopy and chromatography techniques. Spectroscopy, including UV-Visible spectroscopy, elucidates molecular properties by analysing the absorption of electromagnetic radiation, while chromatography enables the separation of compound mixtures based on differential affinities to stationary …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 14–21 Read article