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14 articles for “Inflammatory Markers”
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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The Relationship Between HbA1c and Inflammatory Markers in Acute Ischemic Stroke with and without Diabetes Mellitus
Abstract: Background: Diabetes mellitus (DM) is a prominent risk factor for acute ischemic stroke (AIS), contributing significantly to morbidity and mortality worldwide. Although inflammatory markers like neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP) are recognized as playing a role in the development of acute ischemic stroke (AIS), their association with diabetes mellitus (DM) in individuals affected by AIS remains uncertain. This study seeks to investigate the differences in …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 57–66 Read article
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Importance of inflammatory marker ratio and lipid profile ratio in Acute Ischemic Stroke
Abstract: Background: Acute Ischemic Stroke is a chronic inflammatory disease that is projected to be one of the leading causes of mortality affecting millions of people globally. It is essential to study the Platelet lymphocyte ratio (PLR), Neutrophil lymphocyte ratio (NLR) ratios and C reactive protein (CRP) in impacting the inflammatory status during stroke. It is also important that altered lipid metabolism could influence the inflammatory conditions associated with AIS. Hence …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 19–31 Read article
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Comparative Evaluation of GPBB and CK-MB in Early Diagnosis of Acute Myocardial Infarction in Diabetic and Non-Diabetic Patients
Abstract: Background: Acute myocardial infarction (AMI) continues to be a leading cause of morbidity and death among people worldwide. To lower the risk of problems, early and precise diagnosis is essential, particularly for diabetes patients. The study investigates the diagnostic value of Glycogen Phosphorylase BB (GPBB), a potential early biomarker of myocardial necrosis, and compares it with CK-MB, a widely used cardiac marker, in AMI diagnosis. Inflammatory markers (hs-CRP, IL-6, TNF-α) …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 33–37 Read article
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Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Rheumatoid Arthritis and its Relationship with Vitamin D, ESR, and Obesity
Abstract: Recent years have seen a rise in the prevalence of rheumatoid arthritis (RA), a disease marked by the destruction of articular cartilage and ankylosis of the joints, as well as other complications such as diffuse lung inflammation, sclera, pleura, pericardium, and nodular lesions, which are also common in subcutaneous tissue. Reviewing RA symptoms, diagnosis, treatment, and associations with vitamin D, ESR, and obesity was the aim of the study. Even …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 06–12 Read article
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Necrotizing Enterocolitis (NEC): A Devastating Neonatal Gastrointestinal Disorder
Abstract: Necrotizing enterocolitis (NEC) represents a formidable challenge in neonatal medicine, particularly afflicting premature infants with its characteristic features of severe intestinal inflammation and necrosis. Despite advancements in neonatal care, NEC continues to exact a heavy toll, standing as a prominent cause of morbidity and mortality in this vulnerable population. Its multifaceted etiology, encompassing prematurity, enteral feeding practices, alterations in microbial colonization, and episodes of intestinal ischemia, underscores the complexity of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 78–83 Read article
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Physiological and Psychological Effects of Ekadashi Upavasa (Fasting Ritual) on Women: A Prospective cohort study on Metabolism, Immunity, and Mental Clarity
Abstract: Background: Ekadashi Upavasa, a traditional bi-monthly fasting ritual, is believed to offer physical, mental, and spiritual benefits. However, its scientific impact on metabolism, immunity, and mental clarity remains underexplored. This prospective cohort study evaluates these effects among women practicing the ritual at Krishna Temple, Amloh, over six months. Methods: A total of 800 women aged 25–50 years were recruited from Krishna Temple, Amloh, for this study, conducted from June 2024 …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 67–70 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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Clinical Evaluation of Efficacy of a Polyherbal Unani Formulation (Mentioned in Makhzan-Ul-Ilaj) in the Management of Warm-e-Lauzatain-Haad (Acute Tonsillitis)
Abstract: Background: Warm-e-Lauzatain-Haad (Acute Tonsillitis) is an inflammatory condition of the palatine tonsils characterized by throat pain, fever, odynophagia and general discomfort. It is particularly common among adolescents and young adults and contributes substantially to outpatient visits and missed academic or workdays. In Unani medicine Warm-e-Lauzatain is described as a hot inflammatory swelling arising from deranged humors, exposure to irritants or descending catarrhal matter. Classical Unani texts including Makhzan-ul-Ilaj, advocate the …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 13–22 Read article
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
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Sudarshan Kriya Intervention and Rise of Protective Prostaglandins in Advanced-Stage Breast Cancer: Double-Blind, Randomized, Controlled Trial
Abstract: Background: Breast cancer patients in advanced stages of cancer are managed by palliative care. This study reports important prostaglandin changes observed with added intervention of Sudarshan Kriya in their ongoing palliative care. Level of Prostaglandin A₂ (PGA₂) indicates tumor growth suppression; its level rises if person’s general condition is good, physically fit and active while PGE₂ and D₂ are considered pro-inflammatory. Quantitative assessment of Prostaglandins was done pre and post …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 · pp. 62–68 Read article
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Environmental Impact of Ghaf Tree (Prosopis cineraria) on Heavy Metals Concentration in Atmosphere
Abstract: The Ghaf is a hardy tree, drought-resistant, and can grow up to ten meters in height, it tree produces small, yellow flowers which attractive to many habitats, like bees, insects, and birds. The leaves and pods of the Ghaf tree have significant antioxidant and anti-inflammatory properties and can be used in new drug development. Ghaf trees can adapt to changing environmental conditions and planting Ghaf trees could be an effective …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 1–7 Read article