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55 articles for “Gastrointestinal tract”
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Unusual Foreign Bodies in Gastrointestinal Tract: A Three-year Experience in a Tertiary Care Hospital
Abstract: Background: Majority of foreign body ingestion occurs in paediatric population with a peak incidence between ages of 6 months and 6 years. In adults, foreign body ingestion occurs more commonly in those with psychiatric disorders, developmental delay, alcohol intoxication, and in incarcerated individuals seeking gains via release to a medical facility. Materials and Methods: This prospective observational study was done in a tertiary care hospital of northern India over a …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 1, 2022 · pp. 25–29 Read article
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A Conceptual Study of Anatomy and Physiology of Anal Canal
Abstract: A detailed descriptive study of anatomy and physiology of the body as a whole and individual parts or organs is the chief tool to reach a proper diagnosis. The anorectal area besides being complex structurally and functionally is the commonest site for diseases of lower Gastrointestinal tract. Thus, great stalwarts of anorectal surgery Milligan and Morgan and McGregor have provided detail description of the part, the aspects of general as …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 3, 2021 · pp. 1–8 Read article
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Exploring the Impact of Gut Microbiota in COVID-19 Immune Resilience
Abstract: Gut microbiota—the community of microorganisms that live in the human gastrointestinal tract—has found to play a significant role in the immune system and overall health of individuals. Recent studies have indicated a possible link of gut microbiota with COVID-19, the respiratory illness caused by the SARS-CoV-2 virus. Studies have shown that individuals with COVID-19 often experience gastrointestinal symptoms such as diarrhea, nausea, and vomiting, indicating that the virus may also …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 13, Issue 2, 2023 · pp. 21–24 Read article
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Probiotics in Food Science: Microbial Health Benefits and Future Trends
Abstract: Probiotics are mostly recommended as supplements by the doctors to administer nutritive and healthy benefits. Probiotic foods vary in different forms from yogurts to granola bars. It contains lactic acid bacteria and Bifidobacterium which makes the gastrointestinal tract healthy and whose mode of action involves epithelial barriers, and enhancement in the rate of adhesion to the intestinal mucosa. It helps to get rid from inflammatory diseases, acne, photo-aging, cancer and …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 9, Issue 3, 2020 · pp. 12–15 Read article
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Unraveling the Nexus: Parkinson's Disease, Alpha-synuclein, Desulfovibrio, and the Gut Microbiome
Abstract: Parkinson's disease (PD) is now recognized as a chronic condition which is once considered a highly intricate disorder involving the central, autonomic, and enteric nervous systems. The prevailing perspective attributes the disease by the formation of Lewy bodies, primarily triggered by the misfolding of α-Synuclein, leading to the demise of dopaminergic neurons in the substantia nigra. Constipation, one of the most common non-motor symptoms in PD patients, is believed to …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 18–28 Read article
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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Determining the Antimicrobial Activity of Lactic Acid Bacillus against Candida albicans
Abstract: Candida albicans is human commensal yeast that colonizes the gastrointestinal tract in over half of healthy individuals. Candida are almost universal in low numbers on healthy adult skin and C. albicans is part of the normal flora of the mucous membranes of the respiratory, gastrointestinal and female genital tracts. The present study was carried out to determine their antimicrobial and antagonistic effect against the Candida albicans. The Lactic Acid Bacillus …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 2, 2018 · pp. 1–5 Read article
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Prevalence and Associated Risk Factors of Major Gastrointestinal Nematodes of Cattle in Hawassa City.
Abstract: Gastrointestinal nematodiasis is a major constraint of livestock production causing huge economic loss to livestock sector of a country. A cross-sectional study aimed to assess prevalence of major gastrointestinal nematodes and associated risk factors was conducted from February 2021 to November 2021 in Hawassa city. In the study, fecal samples were collected from randomly selected 384 cattle and coprological examination was employed by using floatation method. The study result revealed …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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Studies on Development of a Super Adsorbent Polymer for the Removal of Nitrogenous Waste Products from Urine Samples and in Intestinal Fluid Simulator
Abstract: Introduction: Colonic dialysis (CD) has been proposed as an appropriate candidate for excretion of electrolytes, nitrogen waste products and excessive fluid using gastrointestinal (GI) tract. Methods: The GI environment simulated in terms of concentrations of nitrogenous waste products, electrolytes, temperature and pressure. In addition, 24-hour urine samples were obtained from 10 healthy adult volunteers. Adsorbing capacity of Super Adsorbent Polymer (SAP) evaluated in GI tract simulating system and urine samples. …
Published in Journal of Polymer & Composites · Vol. 10, Issue 2, 2022 · pp. 1–7 Read article
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A Review on Study of Effect of Guaifenesin
Abstract: Guaifenesin is a very commonly used and prescribed oral expectorant drug. However, its mechanism of action is not completely elucidated and the available information is limited. The purpose was to evaluate whether guaifenesin action on respiratory tract secretion is mediated through a reflex stimulation of the gastric mucosa or by the systemic exposure due to the absorption of the drug to the blood circulation. It was demonstrated that expectorant action …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 7, Issue 3, 2020 · pp. 8–11 Read article
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The Role of Gut Microbiota in the Health Effects of Fermented Dairy Products
Abstract: The human gut microbiota plays a crucial role in maintaining physiological health, influencing digestion, metabolism, immune function, and even mental well-being. Among dietary interventions aimed at modulating gut microbiota, fermented dairy products have emerged as particularly promising due to their rich content of live microorganisms, bioactive compounds, and nutrients. This review explores the intricate interactions between fermented dairy products and the gut microbiota, highlighting their potential health benefits and underlying …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 14, Issue 2, 2025 · pp. 5–10 Read article
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Pharmacokinetic Study of Iron Absorption from Unani Compound Formulation in Animals
Abstract: Background: Iron is an indispensable element for survival and normal functioning of the human cells. It is required for a large number of biochemical reactions in the cells. It is a vital component of haemoglobin, myoglobin, cytochromes, catalases and many other enzyme systems like Krebs cycle. It is essential for oxygen transport and oxidation reactions in cells. Iron deficiency is the most prevalent deficiency disorders of human beings in the …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 1, 2023 · pp. 1–5 Read article
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Enhancing Peptic Ulcer Therapy: Innovations in Mucoadhesive Drug Delivery
Abstract: Peptic ulcer disease is still a sincere gastrointestinal demand makes medication administration difficult because of the harsh and changing stomach environment. This paper investigates the potential of using mucoadhesive drug delivery devices to improve the accuracy and effectiveness of peptic ulcer therapies. Due to the inherent characteristics of mucoadhesive drug delivery systems, localized and sustained drug release is made possible by their extended contact and adherence to the gastrointestinal tract's …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 62–76 Read article
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An Effective & Novel Approach as Gastro-retentive Drug Delivery Systems
Abstract: Researcher’s curiosity about gastro-retentive drug delivery system increased so high in recent years because of its excellent drug releasing properties to the target site. The delivery system's residence time in the stomach can be extended with the usage of gastro-retentive drug delivery system by using a number of natural and synthetic polymers such as guar gum, hydoxy propyl methyl cellulose which can be used to improve the bioavailability of a …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 47–54 Read article
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Angioedema-Diagnosis & Management
Abstract: Angioedema (AE) encompasses a diverse range of conditions categorized into three main groups: (1) angioedema mediated by histamine (AE-H); (2) angioedema mediated by bradykinin (AE-BK); and (3) angioedema with an unknown mechanism (AE-UNK). It can manifest on any part of the body, though commonly affected areas include the face, lips, mouth, throat, larynx, extremities, genital regions, and gastrointestinal tract. AE-H can occur by itself or in conjunction with chronic urticaria, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 9–21 Read article
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A Prospective Observational Study of Prescription and Quality of Life: Gastroesophageal Reflux Disease in Territory Care Hospital
Abstract: Aims and objective: The main aim of the study is to know the quality of life in GERD patients and the management of GERD with the help of prescription patterns and patient counseling. Methodology: After receiving approval from Departmental Research Committee AIPBS with the reference no AIPBS/2021/4586/11 on dated 30 September 2021 and also approved from the Ethics Committee of Biomedical and Health Research, Adesh University with the reference no …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 14–21 Read article
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Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
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Mind-Gut Connection: The Psychosomatic Effects of Stress and Emotions on Digestive System
Abstract: Stress, understood as an immediate disruption to bodily equilibrium, triggers an adaptive or allostatic response that impacts gastrointestinal function both in the short and long term. The enteric nervous system communicates in both directions with the brain through parasympathetic and sympathetic pathways, collectively forming what is known as the brain-gut axis. Unani scholars describe stress as a response to the loss of something valuable, such as an opportunity, a desired …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 11–14 Read article
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Formulation Development and Evaluation Technique for Immediate and Modified Release Capsule
Abstract: The development and evaluation of formulations for immediate-release (IR) and modified-release (MR) capsules represent a critical aspect of pharmaceutical dosage form design, offering distinct advantages in terms of drug release profiles and therapeutic outcomes. This study focuses on the formulation strategies, techniques, and evaluation methods used to develop both IR and MR capsules. Immediate-release capsules are designed to disintegrate quickly in the gastrointestinal tract, ensuring rapid drug absorption, while modified-release …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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Phytochemical, Pharmacological and Toxicological Studies of Solanum americanum: A Systemic Review
Abstract: Solanum americanum, a plant widely used in folk medicine, has recently gained attention in the scientific community due to its diverse therapeutic potential. The bioactive compounds found in different plant parts, such as alkaloids, flavonoids, and tannins, have significant medicinal effects. These compounds exhibit several pharmacological properties, such as antimicrobial, anti-inflammatory, anticancer, and antioxidant effects. However, despite these medicinal benefits, some compounds show significant toxicity to the human body if …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 2, 2025 · pp. 52–62 Read article