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62 articles for “Blood Disorder”
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An Effective Convolutional Neural Network for Identifying Cancer Blood Disorder Cells Using Microscopic Images
Abstract: Blood, bone marrow, and lymphatic systems are all impacted by hematological cancer is known as a cancer blood disorder. Blood malignancies and various blood disorders pose significant health challenges across all age groups. Early disease detection is essential for effective cancer blood disorder treatment and management. If a blood cancer is not identified in time, it may be hazardous. It results in abnormal white blood cell production by the bone …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 2, 2024 · pp. 29–35 Read article
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Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
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The Curious Case of the Sphered Blood Cells: Unveiling Hereditary Spherocytosis
Abstract: Hereditary spherocytosis (HS) is an inherited blood disorder that disrupts the shape and flexibility of red blood cells (RBCs) due to genetic mutations. These abnormal, sphere-shaped RBCs, called spherocytes, are prematurely destroyed in the spleen, leading to hemolytic anemia. Symptoms range from mild fatigue to chronic weakness and shortness of breath. While incurable, Hereditary spherocytosis can be effectively managed. Regular monitoring, folic acid supplementation, and in severe cases, splenectomy (surgical …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 1, 2024 · pp. 49–57 Read article
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A Python-Based Investigation of Clinical Data and Ultrasound Images for PCOS Diagnosis
Abstract: PCOS is a common endocrine disorder that impacts women in their reproductive years characterized by irregular menstrual cycles, hyperandrogenism, and polycystic ovaries. The full diagnostic plan is mainly a combination of a pelvic ultrasound besides blood tests of specific parameters that indicate the presence of PCOS. Since PCOS is a hard-to-diagnose widespread hormonal disorder, blood tests, symptoms, and other parameters with the help of a computer can form a new …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Advanced Deep Learning Techniques for Sickle Cell Anaemia Detection
Abstract: Sickle Cell Anemia (SCA) is a prevalent genetic blood disorder characterized by the presence of abnormal hemoglobin, resulting in the distinctive sickle shape of red blood cells. Timely and accurate identification of Sickle Cell Anemia (SCA) is essential for effective management and treatment. This study presents a new method that utilizes Convolutional Neural Networks (CNNs), a deep learning model particularly effective for image analysis. The process involves using microscopic images …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 9–15 Read article
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Formulation and Analyzation of Murraya Koenigii Herbal Antimicrobial Cream
Abstract: A person's skin is a crucial indicator of their overall health. Everyone experiences skin issues from time to time in their lives. Wrinkles, acne, pimples, dark spots, hypersensitivity, and atopic dermatitis are some of the ways they might manifest. The aim of this project was to formulate the herbal cream for the purpose of the moisturising, cooling, cure inflammation, itching, skin eruptions, persistent boils, wound healing, antimicrobial, and treatment of …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 8–14 Read article
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The Reaction About Anti-Hypertensive Drugs According to Plasma Renin-Aldosterone States
Abstract: With recent studies, hypertension has not only a simple pathophysiology, thus it can classify details more about and establishing drug therapy strategies compatible with it is a very important method to improve the organ predictive of patients. The purpose of this study is to compare the responsibility of some anti-hypertensive drugs in hypertensive patients according to plasma renin-aldosterone levels, which becomes the background factor of hypertension. We investigated 71 hypertensive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 14–23 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Review on Elaeocarpus Ganitrus (Rudraksha)
Abstract: The seed of Elaeocarpus Ganitrus, also known as Rudraksha, is renowned for its electromagnetic characteristics. Recent scientific research has demonstrated that this seed possesses natural electromagnetic properties which can effectively treat various chronic diseases. This study focuses on the phytochemical screening and thin layer chromatographic analysis of the extract obtained from Elaeocarpus Ganitrus seeds, which belong to the Elaeocarpaceae family. Bombay, and is commonly grown as an ornamental tree in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 8–15 Read article
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Holistic Concept & Management of Male Sexual Disorders in Integrative Unani Medicine
Abstract: Sexual medicine or sexology is a multidimensional field that encompasses a wide variety of sexual dysfunctions and their management by counseling, sex therapy, and drugs. It is very difficult to know the actual prevalence of sexual problems in India. It is estimated that 5 –15% of persons of reproductive age group suffer from sexual disorders or have unsatisfactory sexual relationships. The most common sexual disorders include erectile dysfunction, ejaculatory disorders, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 18–24 Read article
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Advancements in Nanotechnology and Biosensor Integration for Detection and Treatment of Alice in Wonderland Syndrome
Abstract: Alice in Wonderland Syndrome (AIWS) is an uncommon neurological condition characterized by profound distortions in perception. Individuals with AIWS experience altered body image and spatial awareness, often perceiving objects, surroundings, or even their own body as being unusually large, small, or distorted. The condition presents a unique challenge for both diagnosis and management due to its elusive and varied symptoms. This paper explores how advancements in nanotechnology and biosensor integration …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 3, 2024 · pp. 1–12 Read article
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Non-Invasive Glucose Monitoring Device Using Max30102 Sensor
Abstract: Diabetes mellitus is a chronic metabolic disorder affecting millions globally, requiring continuous blood glucose monitoring to prevent complications such as cardiovascular disease, kidney failure, neuropathy, and retinopathy. Conventional invasive finger- prick techniques result in pain, skin irritation, and an increased risk of infection, which lowers patient compliance, particularly in young patients and the elderly. This paper presents a non-invasive glucose monitoring prototype using the MAX30102 optical biosensor interfaced with the …
Published in Journal of Instrumentation Technology & Innovations · Vol. 16, Issue 1, 2026 · pp. 36–44 Read article
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Comprehending and Managing Restless Leg Syndrome
Abstract: An need to move that arises during rest or is made worse by rest, that happens in the evening or at night, and that goes away or gets better with movement is the hallmark of restless legs syndrome (RLS), a frequent sensorimotor disease. The degree, frequency, and age of start of symptoms vary greatly; severe types can impair mood, quality of life, and sleep. Periodic leg movements are common in …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 1–6 Read article
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The Study of Nutritional Requirements and Physiological Changes in Space Station
Abstract: This article focuses on the impact of physiological adaptations to weightlessness on nutrient and food requirements in space. These modifications entail reductions in body water and plasma volume, which affect the cardiovascular and renal systems. Spaceflight poses intricate and predominantly detrimental effects on the human body, spanning both short and long durations. Long-term weightlessness leads to significant issues like muscle atrophy, skeletal deterioration, cardiovascular function deceleration, reduced red blood cell …
Published in International Journal of Nutritions · Vol. 1, Issue 2, 2024 · pp. 7–10 Read article
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Harnessing the Healing Potential of Khamira Abresham Hakim Arshad Wala in the Management of Different Health Conditions
Abstract: Khamira Abresham Hakim Arshad Wala (KAHAW) is a potent Unani remedy that plays a vital role in fortifying the body's vital organs and efficiently reducing free radicals by enhancing levels of antioxidant enzymes. The term 'Khamira' originated from the Unani system of medicine and was first introduced by the esteemed Hakeem during the Mughal period. This preparation involves incorporating herbal drugs into a base (Qiwam) containing sugar or honey, resulting …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2024 · pp. 7–13 Read article
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Tinospora Cordifolia (Willd.) Hook.f. & Thomson: A Review on Herbal Formulations and Health Benefits
Abstract: India has a vast variety of medicinal plants utilised as natural medicines since prehistoric times. Herbal medicine was the main form of treatment earlier in the 20th century because neither antibiotics nor analgesics were readily available. Nowadays, natural plant products are becoming more significant in clinical research since they have no side effects and have greater pharmacological response than allopathic medications. Tinospora cordifolia (Giloy or Guduchi) is a climbing shrub …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 3, 2024 · pp. 14–19 Read article
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Diabetes Prediction Using ML Techniques
Abstract: Diabetes mellitus, commonly referred to as diabetes, denotes a cluster of prevalent endocrine disorders characterized by persistent elevated levels of blood sugar. Diabetes is classified into two main types: type 1 and type 2. Type 1 diabetes arises when the body is unable to produce insulin, while type 2 diabetes involves either insulin resistance or insufficient insulin production. Early detection and intervention are essential to reduce its harmful impacts. The …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 11, Issue 3, 2024 · pp. 1–9 Read article
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Amlodipine induced peripheral edema and gingivitis – A case report.
Abstract: Calcium channel a group of drugs used to treat heart disorders are called blockers. These drugs dilate blood vessels and improve blood flow to heart, these works by preventing calcium flow through ion -specific (L- type) calcium channels in the cell membrane. Amlodipine, a calcium channel blocker in the dihydropyridine class, can cause peripheral edema and drug-induced gingivitis in some patients. In this case, the patient experienced swelling in the …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 45–49 Read article
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Exploring the Pathophysiology of Henoch-Schönlein Purpura (HSP): A Comprehensive Review
Abstract: Blood from tiny veins can leak into nearby tissues, causing purpura, a disorder marked by red spots or patches on the skin that may have an impact on the kidneys. Henoch-Schönlein purpura (HSP) is associated with vasculitis and inflammation of blood vessels. The range of renal conditions associated with purpura includes severe glomerulonephritis and mild proteinuria. For instance, immunological complex accumulation in the renal glomeruli of HSP patients might result …
Published in International Journal of Cell Biology and Cellular Functions Read article
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An Overview of Fanconi Anemia: A Genetic Disorder
Abstract: Fanconi Anemia (FA) is a rare genetic disorder caused by DNA repair defects due to pathogenic variants in one of 21 genes. It is the primary cause of inherited bone marrow failure, marked by pancytopenia. Clinically, Fanconi Anemia (FA) is associated with congenital malformations in multiple systems, resulting in progressive bone marrow failure and heightened cancer risk, especially in the urogenital region and the head and neck. There are approximately …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 19–25 Read article