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Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy Review Article

Tinospora Cordifolia (Willd.) Hook.f. & Thomson: A Review on Herbal Formulations and Health Benefits

  1. Sunlata Thapar Department of Plant Sciences, School of Life Sciences, Central University of Himachal Pradesh, Kangra
  2. Kajal Choudhary Department of Plant Sciences, School of Life Sciences, Central University of Himachal Pradesh, Kangra
  3. Shelja Department of Plant Sciences, School of Life Sciences, Central University of Himachal Pradesh, Kangra
  4. Anukriti Department of Plant Sciences, School of Life Sciences, Central University of Himachal Pradesh, Kangra
  5. Jitender Kumar Department of Plant Sciences, School of Life Sciences, Central University of Himachal Pradesh, Kangra

Abstract

India has a vast variety of medicinal plants utilised as natural medicines since prehistoric times. Herbal medicine was the main form of treatment earlier in the 20th century because neither antibiotics nor analgesics were readily available. Nowadays, natural plant products are becoming more significant in clinical research since they have no side effects and have greater pharmacological response than allopathic medications. Tinospora cordifolia (Giloy or Guduchi) is a climbing shrub of Menispermaceae family used in Ayurvedic medicine system. It is a valuable medicinal plant with a long history of use in traditional medical systems such as Ayurveda, Unani, and Siddha. Since ancient times, Ayurvedic medicine has effectively employed Tinospora cordifolia, and its products are now used for both improved medicinal and financial outcomes. Tinospora cordifolia is mentioned in various ancient literatures such as Charak Samhita, Ashtang Hridya, Sushruta Samhita and Bhava Prakash. The plant is utilized to treat illnesses like arthritis, eye disorders, viral infections, allergic rhinitis, chronic fever, blood sugar regulation, immunity boosting, improved digestion, reduces stress and anxiety. It is also regarded as a strong immunomodulator, bitter tonic, and sharpens the memory. It was also found that Tinospora cordifolia acts as an active component in a number of polyherbal remedies for treating hepatotoxicity. The Indian government's Ministry of AYUSH has recommended this plant as a preventive home treatment for the COVID-19 outbreak. The plant's chemical constituents such as aliphatic compounds, diterpenoid lactones, steroids, sesquiterpenoid, glycosides, phenolics, and essential oils found in the root, stem, and entire plant are responsible for their pharmacological activities. It shows several biological activities such as anti-oxidant, anti-inflammatory, anti-allergic, hepatoprotective, anti-diabetic, anti-stress etc.

Keywords

References (30)

  1. Balkrishna A, Khandrika L, Varshney A. Giloy Ghanvati (Tinospora cordifolia (Willd.) Hook. f. and Thomson) Reversed SARS-CoV-2 Viral Spike-Protein Induced Disease Phenotype in the Xenotransplant Model of Humanized Zebrafish. Frontiers in Pharmacology. 2021;12. doi:10.3389/fphar.2021.635510
  2. Bangwal R, Farswan AS. Pharmacotherapeutic uses of magic herb (Amrita): An updated review article. Int J Pharm Sci Rev Res. 2023;82(1):69–76. doi:47583/ijpsrr.2023.v82i01.012.
  3. Deore S, Baviskar B, Kide A, Shende B, Gachake A, Dahake D. Formulation of herbal candies containing Giloy Satva: A nutritious and palatable herbal confectionery option. Pharm Res. 2023;16(1):146–151. doi:5530/pres.16.1.18.
  4. Devkar S, Deshmukh S, Patil S, Koli S, Khochage P, Chougule N. All rounder of Ayurveda-Tinospora Cordifolia. Int J Pharm Sci. 2023;1(12):580–598. doi:10.5281/zenodo.10423831.
  5. Ganguly D, Ghosh S, Banerjee M, Mandal A, Panja S, Choudhury A. A brief review on different plant parts used as immunity boosting agent. Journal of Applied Pharmaceutical Research. 2022;10(1):1-6. doi:10.18231/j.joapr.2022.1.6
  6. Gautam AS, Singh A, Kumar K. Analysis of therapeutic value of Tinospora cordifolia. Asia Pac J Multidiscip Res. 2020;8(1):27–41.
  7. Jain H. A Review on Healing Properties of Tinospora Cordifolia (Indian Giloy). International Journal for Research in Applied Science and Engineering Technology. 2021;9(5):1114-1118. doi:10.22214/ijraset.2021.34467
  8. Javed D, Anwar S, Pathan S. Comparative antimicrobial efficacy of Ayurvedic formulations; Satva and Ghana of Tinospora cordifolia (Willd.) Miers (Giloy) against commensals and opportunistic pathogens. J Drug Deliv Ther. 2022;12(1-S):23–28.
  9. Joshi SP, Kawale SS, Kasture KA, Deshmane HC, Pingale PL. Potential and therapeutic benefits of Tinospora Cordifolia. J Med Pharm All Sci. 2021;10:2965–2970. doi:22270/jmpas.V10I2.1227.
  10. Joy A, Mansukhbhai BM, Sojeetra NH, Acharya RN. Guduchi (Tinospora Cordifolia [Wild.] Miers) and its Therapeutic External Applications. Indian Journal of Ayurveda and Integrative Medicine KLEU. 2021;2(2):56-63. doi:10.4103/ijaim.ijaim_16_21
  11. Mujahid B Khan, Bharat Rathi. Tinospora Cordifolia-An immunomodulatory drug in Ayurveda for prevention and treatment of Covid-19. International Journal of Research in Pharmaceutical Sciences. 2020;11(SPL1):1695-1699. doi:10.26452/ijrps.v11ispl1.4194
  12. Kumar P, Kamle M, Mahato DK, Bora H, Sharma B, Rasane P, et al. Tinospora cordifolia (Giloy): Phytochemistry, Ethnopharmacology, Clinical Application and Conservation Strategies. Current Pharmaceutical Biotechnology. 2020;21(12):1165-1175. doi:10.2174/1389201021666200430114547
  13. Arti Kumari, Gunjan, C.B Singh, Gaurav. A classical review on Guduchi Taila. Journal of Ayurveda and Integrated Medical Sciences. 2023;8(10):160-163. doi:10.21760/jaims.8.10.24
  14. Lakshman MGR. Guduchi is Powder Dosage Form is used in Treatment of Diabetics Mellitus. International Journal for Research in Applied Science and Engineering Technology. 2021;9(12):1385-1393. doi:10.22214/ijraset.2021.39493
  15. Limbachiya VA, Bhinde SM, Harisha CR, Shukla VJ. A preliminary pharmacognostical and physicochemical evaluation of Guduchyadi Vati: A novel herbal formulation for juvenile diabetes. DPU’s J Ayurveda Homeopath Allied Health Sci. 2022;1(2):64–69. doi:4103/jahas.jahas_1_23.
  16. Malla S, Bista L. Tinospora Cordifolia: A multipurpose miracle plant having medicinal importance: A review. Matrix Sci Pharma. 2021;5(3):54–59. doi:4103/mtsp.mtsp_3_21.
  17. Nazir I, Chauhan RS. Qualitative phytochemical analysis of Tinospora Cordifolia and Withania Somnifera. Pharma Innov J. 2018;7(10):333–336.
  18. Ninama R, Verma A, Mishra M, Nagle A, Pati RK, Meshram R. An exploration of physiological, medicinal and safety aspects of Guduchi (Tinospora cordifolia): A complete Ayurvedic and modern review. J Ayurveda Integr Med Sci. 2022;7(4):62–74.
  19. Patgiri B, Umretia B, Vaishnav P, Prajapati P, Shukla V, Ravishankar B. Anti-inflammatory activity of Guduchi Ghana (aqueous extract of Tinospora Cordifolia Miers.). AYU (An international quarterly journal of research in Ayurveda). 2014;35(1):108. doi:10.4103/0974-8520.141958
  20. Prajwala B, Raghu N, Gopenath TS, Basalingappa KM. Guduchi: its medicinal properties. J Plant Physiol Pathol. 2019;3(2).
  21. Sajith KS, Farhan H. Pharmacological effects of Tinospora Cordifolia:( Giloy) in human body. Pharma Innov J. 2022;11(7):07–10.
  22. Nandy SK, Sarkar D, Goswami R, Sarkar A, Mukherjee S. Role of Tinospora Cordifolia (giloy) in bone maintenance disorder (osteoporosis) by docking analytical study. EPRA Int J Res Dev. 2022;7(4):1–8. doi:36713/epra9806.
  23. Department of Pharmaceutics, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005, Saxena C, Rawat G, Department of Pharmacology, Kharvel Subharti College of Pharmacy, Swami Vivekanand Subharti University, Meerut (U.P.)-250005. Tinospora cordifolia (Giloy) - Therapeutic Uses and Importance: A review. Current Research in Pharmaceutical Sciences. 2019;9(3):42-45. doi:10.24092/crps.2019.090302
  24. Shah MS, Shinde AR, Jagtap DR, Kamble SM, Nagargoje S, Shewale KP, Oswal RJ. Tinospora cordifolia: one of the Ayurvedic plants of Coronil formulation for covid-19. Eur J Biomed Pharm Sci. 2020;7(8):257–267.
  25. Sherly EA, Kumar P, Kumar P, Tripathi A, Sengar P, Tiwari S. Role of five medicinal plants (Giloy/Guduchi, Garlic, Tulsi, Turmeric and Ginger) in human immune system. Int J Innov Sci Res Technol. 2023;8(2):197–205.
  26. Shinde DL, Pawar VB, Katkar SR, Kulkarni S. Study of Guduchi Kwath (Tinospora Cordifolia) in patients of dengue fever with Thrombocytopenia. J Surv Fish Sci. 2023;10(4S):3166–3174.
  27. POTENTIAL ROLE OF GILOY (AN IMPORTANT TRADITIONAL AURVEDIC MEDICINAL DIOECIOUS CREEPER) AS AN IMMUNOMODULATOR. Adalya Journal. 2021;10(6). doi:10.37896/aj10.6/006
  28. Tripathi B, Rani R. Development of herbal lassi using giloy stems juice (Tinospora cordifolia). Pharm Innov J. 2021;10(12):2242–2246.
  29. Tyagi P, Chauhan AK. Effect of storage period on chemical parameters and sensory admissibility of cookies incorporated with stem powder of giloy (Tinospora cordifolia). J Pharmacogn Photochem. 2019;8(3):739–742.
  30. Vediya P. Herbal based effervescent granules of Giloy Sattva. Quaderns. 2022;10(12):157–166.
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