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220 articles for “Multi-targeted”
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Managing Carpal Tunnel Syndrome: Insights into Symptoms and Relief
Abstract: Carpal tunnel syndrome (CTS) is a prevalent and concerning issue affecting the wrist and hand, arising from the compression of the median nerve within the carpal tunnel. This compression results in a spectrum of distressing symptoms, including numbness, tingling, weakness, and discomfort, particularly in the thumb, index, and middle fingers. Despite its frequent association with repetitive hand movements and prolonged use of computers or handheld devices, CTS can stem from …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 6–12 Read article
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Metals and Minerals in Pharmacy: Current Trends, Biomedical Applications, and Future Innovations
Abstract: Metals and minerals have played important roles in medicine for centuries, ranging from the use of simple mineral powders in traditional therapies to the development of modern metal-based drugs and nanomaterials. In recent years, advancements in material science, nanotechnology and pharmaceutical engineering have expanded the biomedical relevance of inorganic materials far beyond their conventional use as excipients. This review highlights the growing integration of metallic and mineral systems into pharmaceutical …
Published in International Journal of Minerals · Vol. 2, Issue 2, 2025 · pp. 12–24 Read article
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Demodex spp. (Acari: Demodicidae) Infestation in Humans: Diagnostic Clues and Therapeutic Approaches to Primary and Secondary Demodicosis.
Abstract: Demodicosis represents an inflammatory dermatosis and adnexal disorder arising from pathologic overgrowth of Demodex mites, primarily Demodex folliculorum and Demodex brevis, which are ubiquitous human ectoparasites residing in pilosebaceous units and eyelid margins. Once regarded as benign commensals, these mites are now recognized as primary drivers or key cofactors in diverse clinical phenotypes, including papulopustular eruptions, pityriasis folliculorum, rosacea-like disorders, blepharitis, meibomian gland dysfunction, and exacerbations of comorbid dermatoses such …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 12–20 Read article
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Biomedical Applications of Green-Synthesized Cobalt Oxide Nanoparticles
Abstract: The biomedical potential of cobalt oxide nanoparticles (Co3O4 NPs) synthesized via green methods is gaining recognition due to their biocompatibility and multifunctionality. This article reviews the antibacterial and anticancer properties of Co3O4 NPs synthesized using Delonix regia leaf extract. Characterization techniques confirmed their nanoscale size and uniform morphology. The antibacterial assay against Escherichia coli revealed significant activity, attributed to enhanced permeability and interaction with bacterial membranes. These findings highlight the …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 1, 2025 · pp. 20–29 Read article
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Gold Nanoparticle Size, Biodistribution, and Toxicity: Insights from DualEnergy CT
Abstract: Dual-energy and spectral computed tomography (CT) have emerged as powerful platforms for noninvasive, quantitative mapping of nanoparticle biodistribution in vivo. By exploiting the energy-dependent attenuation profiles of high-atomic-number (high-Z) materials, these systems enable material decomposition and element-specific imaging, thereby distinguishing nanoparticle signals from those of soft tissues and conventional iodinated contrast agents. Photon-counting spectral CT further enhances this capability by binning individual photons into multiple energy channels, improving spatial resolution, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 2, 2025 · pp. 22–34 Read article
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A Review on Anesthetic Drug Discovery with Computer Aided Drug Design
Abstract: In contemporary medicine, anaesthesia is essential for enabling surgical procedures, pain control, and patient comfort. Finding and creating safe and efficient anaesthetics is crucial to enhancing patient outcomes and developing the medical field. In this review, we provide a comprehensive overview of anesthetic drug discovery with a focus on the integration of computer-aided drug design (CADD) methodologies. Beginning with an exploration of anesthesia mechanisms and targets, we delve into the …
Published in International Journal of Antibiotics Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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Facial Emotion Detection and Its Applications
Abstract: Facial emotion detection (FED) is an interdisciplinary field that integrates artificial intelligence, computer vision, and machine learning to recognize and interpret human emotions based on facial expressions. The development of FED systems has been propelled by advancements in deep learning, particularly convolutional neural networks (CNNs) and recurrent neural networks (RNNs), which enhance recognition accuracy. Feature extraction techniques, including geometric and appearance-based methods, play a crucial role in classifying emotional states. …
Published in International Journal of Optical Innovations & Research · Vol. 3, Issue 1, 2025 · pp. 8–12 Read article
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Geotechnical Analysis and Performance Evaluation of Subgrade Materials in Road Construction
Abstract: Geotechnical engineering plays a pivotal role in the design, construction, and long-term maintenance of infrastructure, particularly in road construction, where subgrade conditions are directly linked to pavement performance, durability, and overall structural integrity. The performance of a road is heavily influenced by the geotechnical properties of the subgrade, making it essential to thoroughly assess these properties in the planning and construction phases. This study comprehensively investigates the geotechnical characteristics and …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 24–29 Read article
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Integrated Tactical Patrolling Stick
Abstract: The Integrated Tactical Patrolling Stick (ITPS) is a smart, multi-functional device developed to support military personnel and forest officers working in isolated and high-risk areas like border zones and dense jungles. It is equipped with a range of defensive and signaling features that enhance user safety and situational awareness during patrol duties. Among its key components are a flashing LED system combined with a siren for alert signals, a laser …
Published in Journal of Power Electronics and Power Systems · Vol. 15, Issue 3, 2025 · pp. 23–31 Read article
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Retained Placenta in Dairy Cows: Causes, Consequences and Effective Strategies for Sustainable Dairy Development
Abstract: Retained placenta (RP) is a common reproductive disorder in dairy cows that poses a significant threat to reproductive efficiency, milk yield, and overall herd productivity. The condition, characterized by the failure to expel fetal membranes within 24 hours post-calving, results from a complex interplay of metabolic, endocrine, nutritional, and management-related factors. Key causative agents include dystocia, twin births, premature calving, mineral imbalances, oxidative stress, immune suppression, and hormonal disruptions, particularly …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 · pp. 1–11 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Uttarabasti in Female Infertility: A Retrospective Analysis of Clinical Outcomes and Safety Profile
Abstract: Background: Uttarabasti (UB) is a specialized Panchakarma procedure involving intrauterine instillation of medicated Sneha, classically indicated in Yonivyapad and Vandhyatwa. It facilitates targeted local drug delivery, bypassing gastrointestinal metabolism and enabling direct therapeutic action at the uterine level. In Ayurvedic understanding, UB achieves Garbhashaya Shuddhi and Apana Vata Anulomana — the two primary pathological corrections considered essential in Vandhyatwa. Infertility affects an estimated 10–15% of couples globally, with a substantial …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 · pp. 1–14 Read article
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The Impact of Climate Change on Jute Production in Gaibandha District, Bangladesh
Abstract: Jute plays a crucial role in Bangladesh’s agricultural economy, especially in Gaibandha District, where it is a key crop for rural livelihoods. However, climate change, characterized by rising temperatures and unpredictable rainfall, poses significant threats to jute production. While numerous studies have explored the broader impact of climate change on agriculture, there is a gap in understanding how localized climate conditions specifically affect jute farming in Gaibandha, with many existing …
Published in International Journal of Climate Conditions · Vol. 2, Issue 1, 2025 · pp. 1–17 Read article
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Optimization of Pesticide Requirement Calculations for IoT-Operated Hexacopter Delivery Systems
Abstract: The integration of Internet of Things (IoT) technology into precision agriculture has transformed pesticide application strategies, enabling resource-efficient and environmentally sustainable practices. This study presents a computational methodology for optimizing pesticide requirements in an IoT-operated hexacopter system, designed for dynamic, data-driven pesticide delivery. Leveraging a fusion of real-time telemetric data from onboard LiDAR, multispectral imaging sensors, and environmental monitoring modules, the system employs predictive analytics and edge computing to calculate …
Published in International Journal on Drones · Vol. 2, Issue 1, 2026 · pp. 08–14 Read article
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An Analytical Study on Learning Difficulties in Estimation Theory Among Undergraduate Engineering Students
Abstract: Estimation Theory is a critical mathematical foundation for all engineering disciplines, enabling learners to model uncertainty, analyse signals, and derive optimal estimators. However, undergraduate students frequently struggle with its abstract properties, complex derivations, and prerequisite statistical concepts. This study investigates the key learning difficulties faced by students across multiple engineering branches using diagnostic tests, structured questionnaires, and interviews. The findings reveal that students commonly experience challenges related to weak probability …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 1, 2026 · pp. 37–41 Read article
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Challenges And Constraints Affecting Female-Owned Rural Farm Businesses in Plateau State, Nigeria
Abstract: This study examined the challenges and constraints affecting female-owned rural farm businesses in Plateau State, Nigeria. No prior study had conducted a comprehensive, quantitative, state-wide investigation covering all 17 local government areas (LGAs) of the state, and this study addressed that gap. The objectives were to identify the challenges faced by female-owned rural farm businesses, assess their relationship with business performance, and determine how strongly these challenges predicted performance outcomes. …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 1–13 Read article
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A Structure-based Design Approach to Catharanthus roseus Phytoconstituents as Potential Inhibitors of B-Cell Lymphoma 6 Protein
Abstract: Objectives: Lymphoma is a cancerous disease. It develops into millions of people worldwide. Identify the naturally active compounds from Catharanthus roseus, they have multiple values in the medicinal field of Siddha, and Indian Ayurveda are used as a disease-preventing agent. Drug illness prediction, toxicity prediction, statistical information, molecular docking, as well as absorption, distribution, metabolism, and excretion (ADME) analysis are used to predict the fit ligand as a drug. Methods: …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 14–34 Read article
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Evaluation of Emergency Response Plans in Industrial Environments Using Simulation Techniques
Abstract: Industrial facilities, particularly those in the chemical, manufacturing, and energy sectors, face significant hazards due to their complex operations and the handling of hazardous materials. Ensuring the safety of workers and minimizing the impact of incidents require robust and effective emergency response plans (ERPs). Traditional evaluation methods, such as drills and tabletop exercises, often fall short in replicating the complexities of real-world emergencies. These methods may lack the realism needed …
Published in Journal of Industrial Safety Engineering · Vol. 11, Issue 3, 2024 · pp. 6–10 Read article
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Asymptomatic Malaria—A Missed Opportunity in the Planned 2030 Malaria Elimination Programme in Ethiopia
Abstract: Background: Malaria intervention in Ethiopia has been strengthened significantly in the past decade with significant reduction in incidence and prevalence. However, continuous surveillance on malaria disease incidence was suggested for effective control and elimination. In difference to this suggestion, malaria elimination programme in the country is missing asymptomatic malaria as a prime target. Thus, the aim of this study was to determine prevalence of asymptomatic malaria and associated factors in …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 1, 2019 · pp. 4–9 Read article