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365 articles for “Humanity”
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Prediction of Molecular Targets for Anthraquinone and Its Analogs for Treatment of Good Pasteur Syndrome
Abstract: Objective: In order to find prospective molecular targets for the treatment of Good Pasteur Syndrome (GPS), a rare autoimmune disease that affects the kidneys and other organs, computational methods and network pharmacology were applied in this work. The goal of the study is to identify particular human proteins that might interact with anthraquinone and its analogues as well as to uncover potential mechanisms of action by which these drugs might …
Published in International Journal of Bioinformatics and Computational Biology Read article
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"Reviving Kali Bein : Addressing the Re-Pollution Sources and and Exploring Solutions for Sustainable River Management"
Abstract: All aspects of the earth’s environmental system are impacted by human assault on the planet that includes vast conversion of land use, extraction of mineral resources, use and misuse of surface water and ground water which altered the natural flow of energy and resources within the environment. This paper reviews the present position of kali ben rivulet, which flows through the state of Punjab in India, has found to be …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 12–26 Read article
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Investigate an Implementation Study of TI-6AL-4V Lattice-based Scaffold Design Using Finite Element Analysis
Abstract: Implementation studies are advised to determine the effectiveness and performance of bone scaffolding in morphology, which has been demonstrated scientifically. The rehabilitation of bone defects, which is still a complex problem in orthopedic surgery, was the subject of an implementation study we provided. Biomaterial scaffolding porosity and pore size are essential in both in vivo and in vitro bone development. However, it has been linked to various drawbacks, including poor …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 28–35 Read article
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Anti Covid-19 Drugs Suggested by Computational Methods: A Review
Abstract: Background and aims: Long COVID refers to the persistence of illness in individuals who have survived from COVID-19 infection. This article reviews long covid and the use of in silico techniques in drug development for COVID-19. Results: Many COVID-19 survivors have long COVID, which has become a burden in daily life. Various attempts have been undertaken to relieve symptoms and manage it, but there is no cure as of yet. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 16–34 Read article
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Exploration of 5-Hydroxybowdichione Flavonoids As Inhibitors of Dengue Virus Ns5 RNA-Dependent RNA Polymerase Using Molecular Docking Approach
Abstract: Objectives: Human lives are now seriously threatened by dengue fever, which is brought on by the dengue virus (DENV). Aedes aegypti mosquitoes, which reproduce in still water, are the primary vectors of the arboviral virus known as dengue. It is well-recognized that phytochemicals have a high potential to eliminate bacterial, viral, and fungal infections in people. Thus, it demonstrates its inhibitory effects on the dengue virus. This study identifies some …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 1, Issue 1, 2023 · pp. 1–16 Read article
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A Critical Study of Research Challenges for Self-adaptive Software
Abstract: Software systems dealing with distributed applications in changing environments normally require human supervision to proceed with activity in all conditions. These rearranging, investigating, and all in all upkeep errands prompt exorbitant and tedious strategies amid the working stage. These issues are principally because of the open-circle structure regularly followed in programming advancement. Hence, there is popularity for administration many-sided quality decrease, administration mechanization, vigor, and accomplishing the majority of the …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 1–6 Read article
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Predicting and Prohibiting the Risk of Heart Failure Using Machine Learning
Abstract: It is challenging to estimate the likelihood of complex chronic disease while treating conditions like heart failure. The application of machine learning, an area of artificial intelligence, in cardiovascular care is growing quickly. In essence, it defines how computers classify and understand data, or choose a task with or without human intervention. The theoretical underpinnings of machine learning are models that accept input data (such as images or text) and …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
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A Study on Breast-feeding Self-Efficacy and Its Associated Factors Among Mothers
Abstract: Introduction: The process through which a kid is fed human breast milk is known as breastfeeding. Breastfeeding has a significant impact on disease prevention and health promotion. It helps to increase bonding with baby and mother. Oestrogen, progesterone, prolactin, and oxytocin are the four primary hormones that contribute to the production of breastmilk. A modifiable element that can improve breastfeeding success and duration is breastfeeding self-efficacy. Aim: To evaluate mothers' …
Published in International Journal of Midwifery Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 31–36 Read article
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Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
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Identification of Secondary Metabolites from Zingiber officinale as Inhibitors for Keap 1-Nrf2 small Molecules through Molecular Docking Techniques
Abstract: Objective: Therapeutic plants aid in treating cancer-based cell signaling pathways and preventing certain risk factors. Zingiber officinale has a variety of anti-inflammatory characteristics also contributing to enhanced immunity, reducing cancer risk and used to target the KEAP NRF2. When overexpressed in response to oxidative stress and DNA damage, elevates the risk of developing multiple cancers. NRF2 cellular sensors, which also control and coordinate their expression aid in defending healthy cells …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 35–48 Read article
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Assessment of Knowledge and Estimated Burden of Life Style Diseases in a Rural Community
Abstract: Although rapid human evolution has brought about advancement, it has also caused several lifestyle ailments. People’s daily routines have drastically changed as a result of emerging technologies, and it paved the way for numerous life style disorders. According to reports, lifestyle diseases are a major cause of increased mortality globally. Our study highlights the prevalence of life style diseases in the rural community and the need for early identification and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 33–38 Read article
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Assessing the Performance of DL Methods in Handwritten Digit Recognition
Abstract: Handwritten digit recognition is a computer vision task that involves the automatic identification and classification of hand-written digits. The objective is to develop models capable of accurately recognizing and distinguishing digits handwritten by humans. With the development of machine learning and deep learning techniques, this field has advanced remarkably. The convolutional neural network (CNN) is the most often used technique for this purpose. By utilizing CNN, the model can learn …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 1, 2023 · pp. 25–32 Read article
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A Review of Optimization of Energy Efficiency Though Phase Change Material in Building
Abstract: Energy use in the construction sector is substantial. Thus, it is crucial that new materials be developed with the intention of improving building thermal efficiency. Thus, over the last few decades, the incorporation of Phase Change Materials has increased. (PCMs) into buildings has gained popularity. Such materials, which have the capacity to both absorb and release energy from/in the environment, can lessen temperature variations, enhancing human comfort while also consuming …
Published in International Journal of Urban Design and Development · Vol. 1, Issue 2, 2023 · pp. 05–12 Read article
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Floating Cities from Concept to Creation :Neighbourhood Guide to the Future Development
Abstract: Today cities are overpopulated and only 40% of space is left to house the world's population by 2050. Due to ever rising sea level 90% of coastal cities will be affected by flooding by the end of the century. This research aims to study about the floating city as a substitute. Floating cities shape to construct all of the infrastructure required for a water-based metropolis while also providing contextual space …
Published in International Journal of Urban Design and Development Read article
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A Molecular Docking Study: Targetting HIV-1 Integrase Protein Against Selected Phytocompounds from Calophyllum Lanigerum
Abstract: Objectives: The most common form of HIV that causes AIDS is HIV-1. The World Health Organization has estimated roughly 75 million plus HIV-1 infections till date and roughly 40 million deaths (as of 2021). Thus, this study was done to identify natural compounds from Calophyllum lanigerum, a medicinal plant largely endemic to South-East Asia, to inhibit the spread of this disease. It did so by using molecular docking methods, Lipinski …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 2, 2023 · pp. 43–55 Read article
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WSN with IoT Using Raspberry Pi as a Tool for Communication
Abstract: Wireless systems based on IoT have developed exponentially in various aspects. The Internet of Things (IoT) is a network in which physical devices, sensors, and other objects communicate among themselves without the involvement of humans. The WSN (Wireless sensor network) is a central component of IoT that has escalated into various applications in the real world. Many industries are turning towards industrial automation as it provides increased efficiency, reduced costs, …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 1, Issue 1, 2023 · pp. 34–42 Read article
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Automobile Collision Detection System Using GSM and GPS
Abstract: The accelerometer detects changes in the vehicle’s axis and the GSM module sends an alert message to the phone indicating the location of the event. Advanced technology makes our daily life easier. Because every coin has two sides, technology has both strengths and weaknesses. The development of technology has increased the number of traffic accidents, resulting in numerous deaths. The poor medical facilities that exist in our country exacerbate the …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 1, 2023 · pp. 15–19 Read article
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Designing a Sustainable Pedal-Powered Washing Machine for Rural Areas
Abstract: The ingenuity can be found in its simple construction, sparse use of pricey components, extremely low upkeep and repair costs, accessibility to all segments of society, and lack of environmental impact. According to the environmental issue, it is essential to use energy in alternative ways in order to conserve it. The PPWM additionally conserves time, water in a container and power while being reasonably priced. The leg-powered washing machine (PPWM) …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 1, 2023 · pp. 20–25 Read article
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Design and Fabrication of Automatic Timetable Generator and its Application
Abstract: Making a schedule manually is exceedingly challenging in today's literate environment. Timetables must be made specifically for each branch and each year. It becomes quite chaotic, time-consuming, and labor-intensive to manually prepare the timetables. When a staff member needs to be substituted or is on leave, the process can occasionally become complicated. In our effort, we have developed a timetable-creation algorithm that will save a lot of time while lessen …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 1, Issue 1, 2023 · pp. 21–25 Read article
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Investigating the Impact of Robotics and Automation on Manufacturing Technology
Abstract: Automation and automated machines have dramatically enhanced quality, productivity, and efficiency in industries such as manufacturing at the past few decades. The current research looks at the ways robotics and automation are impacting industrial technologies. The investigation offers an in-depth analysis of the advantages and difficulties connected with the incorporation of robots and automation in industrial processes by evaluating pertinent literature, case studies, and statistics. Conclusions of this research effort …
Published in International Journal of Manufacturing and Production Engineering · Vol. 1, Issue 1, 2023 · pp. 33–38 Read article