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1046 articles for “Regulations”
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Pharmacokinetic Profiling and Molecular Docking of Carvacrol and Structural Analogs: Targeting Quorum Sensing Proteins to Disrupt Biofilm-Mediated Antimicrobial Resistance in Multidrug-Resistant Bacterial Pathogen
Abstract: Antibiotic resistance, particularly in Pseudomonas aeruginosa, has become a major global health threat, exacerbated by the organism's ability to form biofilms and regulate virulence through quorum sensing (QS). The LuxR and LasR receptors are key regulators in this process, influencing both pathogenicity and antibiotic resistance. This study investigates potential QS inhibitors targeting these receptors as a strategy to mitigate antibiotic resistance. The primary objective was to identify novel ligands that …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 43–61 Read article
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Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine
Abstract: Three-dimensional (3D) printing is particularly influencing the pharmaceutical manufacturing sector in the creation of controlled release drug delivery systems. This technology enables the precise fabrication of personalized medicines with tailored drug release profiles, dosages, and geometries, marking a significant advancement over traditional mass production methods. An array of 3D printing techniques, including extrusion-based, powder-based, and others, can be used to build complex dosage forms that regulate drug release through processes …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 28–43 Read article
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Quality Control and Assurance Practices in Modern Pharmaceutical Industry
Abstract: This brief overview outlines the global techniques for figuring out the prevalence of geotaxis impurities (residual solvents and various inorganic and organic impurities) in medications. It is now necessary to reveal a pharmaceutical product's purity and impurity profiles due to both national and international regulations. These elements are discussed, together with the kinds of impurities, their origins, their control, and regulatory issues, as well as the significance of pharmaceutical quality, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 3, 2025 · pp. 07–13 Read article
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Performance Evaluation of Lithium-Ion Batteries Considering State of Charge and State of Health for Electric Vehicle Applications
Abstract: This study aims to compare temperature-regulated and uncontrolled charging methodologies to determine the most effective approach for optimizing battery performance while minimizing charging duration. The study assesses both constant current (CC) and temperature-controlled pulse charging (TRPC) methods. The battery temperature increases in direct proportion to the applied current during CC charging and cannot be controlled in the absence of external cooling systems. Key performance measures, such as the effect on …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 15, Issue 3, 2025 · pp. 32–47 Read article
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Lesser-Known Metabolites Influencing Ovarian Function, Follicular Development, and Embryo Viability in Dairy Cows
Abstract: The intricate processes of ovarian function, follicular development, and embryo viability in dairy cows are tightly regulated by a complex network of metabolites. While conventional biomarkers, such as steroid hormones, amino acids, and glucose metabolites, have been extensively studied, a growing body of evidence suggests that lesser-known metabolites play pivotal roles in bovine reproductive physiology. Dairy cattle fertility is critical for maintaining optimal milk production and herd sustainability, necessitating deeper …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 18–29 Read article
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A Study on Drone Hacking: Vulnerabilities and Mitigation Techniques
Abstract: This paper explores the current cybersecurity landscape surrounding Unmanned Aerial Systems (UAS), commonly known as drones. With rapid growth in commercial and recreational drone use, the risk of cyber-attacks has also increased. This study highlights real-world vulnerabilities such as GPS spoofing, Wi-Fi hijacking, and firmware exploitation. It also suggests practical mitigation techniques, including encryption, real-time anomaly detection using machine learning, and secure communication protocols. The goal is to support researchers, …
Published in International Journal on Drones · Vol. 1, Issue 2, 2025 · pp. 1–8 Read article
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e-learning Platforms in Higher Education: An Analysis of Institutional Planning, Implementation and Evaluation Strategies
Abstract: This quantitative study investigates the impact of e-learning platforms on student learning outcomes in higher education, focusing on institutional planning, implementation, and evaluation strategies. A descriptive-correlational research design was employed, surveying 100 administrators, faculty, and students from various higher education institutions. The results show significant positive correlations between platform organization, user-friendliness, instructor feedback, technical support, and student motivation. Well-structured platforms with clear communication of learning objectives, quality technical support, and …
Published in International Journal of Education Sciences · Vol. 2, Issue 2, 2025 · pp. 41–49 Read article
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Novel Strategic Framework between Polymer Manufacturers and Waste Management Companies: A Mixed-Method Approach for Enhancing Circular Efficiency in Polymer Industries
Abstract: The study describes the perspectives of the industry stakeholders and qualitatively and quantitatively assesses the recycling efficiency, cost optimization, and environmental performance using a mixed-method approach. The framework features processes, as it were: onboard invention, coupling, and sustainable valorization of the intersection, thus solidly connecting the production side with the waste management. The primary function of the patterns of interaction between the plant waste-management system, the retrieval of polymer composites, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1570–1609 Read article
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An Overview of Microbial Diversity in the Functions of Wetland Ecosystems
Abstract: Wetlands serve as abundant reservoirs of biodiversity, crucial for the well-being of both humanity and the natural world. They represent the most critical and fertile ecosystem, where water predominantly dictates the environment and the plant and animal species that inhabit it. Wetlands have diverse microbial flora and fauna, which play essential roles in ecosystems. Soil and aquatic microorganisms mediate many processes, such as biogeochemical cycles, waste decomposition, symbiotic relationships, and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 1–14 Read article
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Polymers In Low-Resource Biomedical Innovation: Maker Labs, DIY Devices and Ethics
Abstract: The low-cost biomedical devices have been prototyped and sometimes put into practice by maker laboratories and community "DIY" (Do-It-Yourself maker) innovators due to the fast-growing availability of polymer-based fabrication (desktop 3D printing, laser cutting, and simple molding). Nowadays, polymers such as PLA, PETG, TPU, and PEEK are used in a wide range of applications, including surgical guides and anatomical models, as well as assistive technology and diagnostic housings. Such innovations …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 108–119 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Managing Blow-by in Modern Engines: A Comprehensive Review of Crankcase Ventilation Technologies
Abstract: Blow-by in internal combustion (IC) engines occurs when high-pressure combustion gases escape past the piston rings into the crankcase. These gases typically carry oil aerosols, unburned hydrocarbons, and fine particulate matter, which, if not effectively managed, can disrupt lubrication, accelerate component wear, and contribute to harmful emissions. Effective crankcase ventilation is therefore essential not only for ensuring engine durability but also for meeting increasingly stringent emission regulations. This paper examines …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 317–324 Read article
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Role of Pharmaceutical Software in Vaccine Development and Manufacturing Process Optimization
Abstract: Vaccine development and manufacturing have become increasingly complex due to the emergence of diverse vaccine platforms, stringent regulatory expectations, and global demand for safe and effective immunization. Across the vaccine lifecycle – from antigen design and preclinical evaluation to large‑scale manufacturing and post‑marketing surveillance – pharmaceutical software now plays a central role in handling data, optimizing processes, and ensuring regulatory compliance. Software tools support in silico antigen and epitope design, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 1–8 Read article
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Thermodynamic Irreversibility in Semen Transport
Abstract: Sperm ejaculation is a vital reproductive process that involves both complex biological functions and energetic mechanisms. Beyond the physiological aspects, thermodynamics offers a framework to analyze energy conversion, exergy use, and irreversibility during sperm activity. ATP provides the main source of exergy for motility, but part of this energy is inevitably lost as heat and entropy generation, reflecting inefficiencies in the process. Because heat regulation directly affects metabolic rates, motility …
Published in Journal of Thermal Engineering and Applications · Vol. 13, Issue 1, 2026 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Consumer Awareness and Adoption Barriers of E-Pharmacy Services in Delhi/NCR: A Mixed-Methods Investigation
Abstract: Background: The rapid digitization of India's pharmaceutical market has positioned e-pharmacies as a transformative force; yet, consumer adoption remains significantly low despite growing awareness. Objectives: This study investigates consumer awareness levels, purchasing behaviors, trust perceptions, and adoption barriers regarding e-pharmacy services among urban Indian consumers. Methods: A sequential explanatory mixed-methods design was employed. Quantitative data were gathered via a structured questionnaire administered to 65 respondents in Delhi. Qualitative insights were …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Polymer-Based Acoustic Composite Materials for Urban Noise Mitigation: Design, Performance and Legal Integration
Abstract: This study explores the development and use of polymer-based acoustic composite materials for effective urban noise mitigation, wherein the performance of the materials is linked to legal compliance frameworks. Rapid urbanization has intensified noise pollution from transportation, industrial activity, and construction, posing a serious threat to public health and environmental quality. Although regulatory standards exist, their implementation is often limited due to inadequate technical interventions. This research focuses on advanced …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 403–412 Read article
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Explainable Artificial Intelligence in Personalized Medicine: Emerging Clinical Perspectives
Abstract: The convergence of artificial intelligence (AI) and precision medicine has transformed contemporary healthcare by enabling data-driven clinical decision-making, individualized therapeutic interventions, and predictive diagnostics. However, despite remarkable advances in machine learning (ML) and deep learning (DL), the widespread adoption of AI in healthcare remains constrained by the “black-box” nature of many computational systems. Clinicians, regulatory agencies, and patients increasingly demand transparency, interpretability, and trustworthiness in AI-guided medical recommendations. Explainable Artificial …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 13–29 Read article
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Ashaya as Abode: Reconciling Ayurvedic Vata Theory with Intestinal Neurophysiology
Abstract: Background-Ashaya refers to a site or structure within the body where a substance resides. Ashaya refers to the internal sites or structures within the body where various substances reside Commonly, seven Ashayas are described in males, while in females there are eight, while Sharangadhara has described 9 Ashayas. Vatashaya denotes the specific site of Vata Dosha, which is considered the chief among the three Doshas due to its vital role …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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Twisting, Super Twisting and Adaptive Algorithm Sliding Mode Controller for Second Order Time Delay Systems
Abstract: The sliding mode control approach is widely considered as one of the most effective methods for designing a reliable controller for a complicated higher-order dynamic plant operating under uncertainty. The primary advantages of sliding mode is its low sensitivity to changes in plant parameters and the ability to entirely eliminate disruptions. Sliding mode control has been widely applied as a robust control design methodology that is completely insensitive to uncertainties, …
Published in Current Trends in Signal Processing Read article