Search
412 articles for “PKA/CREB pathway”
Nothing matched all of your words, so these match any of them.
-
Bioremediation Strategies to Address the Menace of Oil Spills
Abstract: Bioremediation is an innovative and effective process that leverages the capabilities of microorganisms to address and mitigate contamination in both soil and water environments. This technique is particularly valuable in the context of surface oil spills, where it presents significant advantages over traditional physical and chemical remediation methods. Unlike physical methods, which often involve the use of barriers and skimmers to remove oil from the surface, or chemical methods, which …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 3, 2024 · pp. 43–56 Read article
-
Catalyst: Free Synthesis of Bioactive Molecules via Green Chemical Principles
Abstract: This study explores the catalyst-free synthesis of bioactive molecules, emphasizing the application of green chemical principles. Traditional synthetic methods often rely on hazardous reagents, solvents, and metal catalysts, which can pose significant environmental and health risks. In contrast, the catalyst-free approach leverages benign reaction conditions, such as solvent-free systems, ambient temperature, and pressure, to achieve efficient and selective transformations. We present a comprehensive investigation into various bioactive molecule syntheses, including …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 17–21 Read article
-
Virtual Voyages: Navigating Museum Education with Electronic Games
Abstract: The incorporation of electronic games into museum environments is becoming increasingly popular as an effective educational resource. These games offer a dynamic way to engage visitors, enhancing their overall experience by catering to diverse learning styles and effectively capturing the attention of a digital-native audience. By integrating interactive components, museums can enhance the learning experience, making it more engaging and enjoyable, which subsequently boosts knowledge retention. This approach has the …
Published in Current Trends in Information Technology · Vol. 14, Issue 3, 2024 · pp. 34–38 Read article
-
Microalgae: Promising Sources of Biofuels
Abstract: Single-celled photosynthetic organisms known as microalgae have drawn a lot of interest as a potential source for the synthesis of biofuel. These microscopic organisms are able to effectively convert sunlight and carbon dioxide into biomass that is high in proteins, carbs, and lipids. Microalgae makes up to 19% starch concentration providing an eco-friendly and sustainable way to satisfy the growing need for renewable energy sources.Although they can be made from …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 3, 2024 · pp. 1–12 Read article
-
Polymeric Approach in Microplastic Degradation Mechanisms
Abstract: Microplastics (> 5 mm size), are silently infiltrating ecosystems on a global scale. The persistence of microplastics in terrestrial and aquatic surroundingss poses a significant ecological and surroundings challenge. Thus, understanding and development of effective degradation mechanisms to mitigate the persistence of microplastics in the surroundings is required. Natural degradation pathways, such as photodegradation, biological degradation, and abiotic degradation have been explored. Polymeric materials possess unique properties that can be …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 165–172 Read article
-
Secondary Metabolites in Drug Development: Tracing Their Historical and Therapeutic Impact
Abstract: Secondary metabolites, also known as natural products, exhibit a level of structural and chemical diversity unmatched by synthetic small molecule libraries. These compounds, which have evolved to possess drug-like properties, continue to be a primary source for new medications and drug leads. Their discovery has significantly impacted advancements in chemistry, biology, and medicine, influencing drug development and therapeutic strategies throughout history. Derived from primary metabolic pathways such as photosynthesis, glycolysis, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 51–55 Read article
-
The Role of Pyruvate Dehydrogenase in Non-Alcoholic Fatty Liver Disease: Therapeutic Insights and Future Directions
Abstract: Non-alcoholic fatty liver disorders (NAFLD) are defined by the accumulation of excess fat in the liver that has no other cause, such as drinking alcohol. Pyruvate dehydrogenase has been established as an alternative treatment for this disorder. NAFLD pathogenesis is complex and includes oxidative stress inflammatory processes and mitochondrial dysfunction. Impaired liver fatty acid oxidation and glucose oxidation are significant individuals in developing NAFLD, and strategies to reverse these defects …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 44–51 Read article
-
Strategy to Accelerate the Biopharmaceuticals Production Using Komogataella phaffii (Pichia pastoris)
Abstract: Revenue generation has been the primary goals for nations as well as the industries worldwide. Biopharmaceutical verticals have become potential revenue generators as they are the industrial workhorses and the economic engines that drive the upcoming biopharmaceutical industries with advances in DNA recombinant technology. A breakthrough in the indusrial biotechnology for the production of biopharmaceuticals using Pichia pastoris is awaited. Ablynx NV, Recombinant proteins (RP), HSA-pFSH beta, antibodies, borosin, N-glycoprotein, …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
-
Geochemometric Assessment of Primordial Radionuclides and Trace Elements in Coastal Sediments: Environmental and Radiological Implications for South India
Abstract: This study focuses on environmental radioactivity and trace element contamination in coastal sediments along the southern region of the Indian subcontinent, from the Palar River to Pulicat Lake. Utilizing gamma-ray spectroscopy with a NaI (Tl) detector, along with atomic absorption spectroscopy, the research examines the spatial distribution and activity concentrations of primordial radionuclides—namely, 238U, 232Th, and 40K—as well as trace elements such as Ni, Pb, Mn, Zn, Cu, Co, Fe, …
Published in International Journal of Minerals · Vol. 1, Issue 1, 2024 · pp. 33–37 Read article
-
Role of Crispr-Cas9 in Plants
Abstract: The innovative CRISPR Cas9 system has emerged as a game changing genetic engineering tool in years offering levels of precision, efficiency and flexibility in editing the genomes of various organisms, including plants. This summary aims to provide an examination of the role of CRISPR Cas9, in modifying plant genomes highlighting its benefits, drawbacks and possible uses. Thanks to its versatility and user-friendly nature CRISPR Cas9 technology has expedited studies in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 1–10 Read article
-
Advancements in Molecular Engineering: Innovations at the Nexus of Chemistry and Technology
Abstract: Molecular engineering, a frontier of chemistry, merges precision and innovation to design and assemble molecular structures with unprecedented control. This abstract explores recent advances, highlighting key breakthroughs and their transformative impacts. Starting with its roots in chemical synthesis and materials science, it traces the evolution towards rational design driven by computational tools and advanced characterization techniques, enabling tailored molecular architectures. A focal point is programmable molecules, where DNA nanotechnology principles …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 37–43 Read article
-
MicroRNAs in Animal Behavior: Regulation of Memory and Decision-Making in Mammals
Abstract: MicroRNAs are small, non-coding RNA molecules that play a crucial role in post-transcriptional regulation of gene expression. In recent years, their significance has extended beyond cellular development and disease regulation, as emerging evidence suggests they are critical mediators in complex behavioral processes, including learning, memory, and decision-making. This article explores the role of miRNAs in regulating neural plasticity and cognitive functions in mammals, emphasizing their involvement in memory formation and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 3, 2024 · pp. 21–25 Read article
-
Microplastics Contaminated Mullet (Mugil cephalus) (Linnaeus, 1758) from the Lower Forcados River, Burutu, Delta State, Nigeria
Abstract: The increasing contamination of the environment by microplastics (MP) in various forms is a consequence of modern lifestyle advancements and has emerged as a significant environmental hazard. The digestive tracts of 36 specimens of the economic mullet (Mugil cephalus) were investigated between March 2022 and March 2023 from the lower Forcados River, Burutu, Delta State, Nigeria. A total of 96 MP particles were extracted from 18 fish out of the …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 3, 2024 · pp. 29–37 Read article
-
Nano-Adsorbents for Water Purification: A Focus on Nanoclays
Abstract: Nanotechnology has emerged as a pivotal tool in addressing contemporary environmental challenges, particularly in water purification. This paper explores the use of nano-adsorbents, focusing on nano-clay materials, as effective solutions for the adsorption and removal of harmful pollutants from water. Nano-clays, owing to their large surface area and unique physicochemical properties, exhibit exceptional adsorption capacity for contaminants such as heavy metals, dyes, antibiotics, and various organic compounds. This review consolidates …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 3, 2024 · pp. 38–44 Read article
-
Human Milk and Infant Growth: A Systematic Review of Nutritional Outcomes
Abstract: Human milk is recognized as the optimal source of nutrition for infants, playing a critical role in their growth and development. This systematic review explores the evidence linking human milk consumption to various growth parameters in infants, including weight gain, length, and head circumference while considering the influencing factors of prematurity and health status. The composition of human milk, rich in essential macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins and …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
-
Exploring the Complexities of Parkinson’s Disease
Abstract: Parkinson’s disease (PD) is a neurological disorder, primarily affecting older adults, marked by both motor and non-motor symptoms. This review explores PD as a multisystem disorder that influences the central, enteric, and autonomic nervous systems, along with the immune system and gastrointestinal tract. Key pathogenic features include the degeneration of dopamine-producing neurons in the substantia nigra and the formation of Lewy bodies containing misfolded α-synuclein proteins. The bradykinesia, tremors, stiffness, …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 3, 2024 · pp. 1–8 Read article
-
Food Processing and Membrane Technologies: Food Industry and Microfiltration
Abstract: Membrane technologies are being used extensively in food processing because they improve the process efficiency as well quality of end product. Microfiltration is one of these most important process in food and beverage industry for separation and purification. Along with a unique pressure driven separation process, microfiltration membranes provide the removal of suspended solids, bacteria and colloids from your product while preserving valuable nutrients and flavors. Microfiltration is extensively used …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 23–27 Read article
-
Nutraceutical Potential of Millets
Abstract: Millets have garnered growing interest because of their exceptional nutraceutical properties. Due to their abundant supply of vital nutrients and bioactive substances, millets show significant potential in enhancing health and reducing the risk of chronic illnesses. This paper emphasises the significant nutritional content of millets, which are devoid of gluten and abundant in protein, vitamins, and minerals, rendering them a superb dietary choice for those suffering from gluten sensitivity or …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 13, Issue 3, 2024 · pp. 31–37 Read article
-
Non-Enzymatic Glycation in Alzheimer’s and Parkinson’s Disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several neurodegenerative diseases, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD). The accumulation of AGEs can significantly alter protein structure, stability, and function, triggering a cascade of detrimental effects, including increased oxidative stress, heightened neuroinflammation, and the promotion …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 36–41 Read article
-
Self-similarities in Hilbert Envelope Energy Regions on Motion Waveforms Application in Detecting Motion Irregularities in Video Frames
Abstract: This paper introduces self-similar Hilbert envelope energy regions that are commonly found in oscillating spectral curves. The time-varying amplitudes and peak value frequencies in typical spectral curves reflect the response of a system to external stimuli. A Hilbert envelope is a smooth curve connected between spectral curve peak values. Each peak value on an envelope curve at time identifies an envelope-bounded region with interior area (called Hilbert envelope energy region …
Published in Trends in Opto-electro & Optical Communication · Vol. 14, Issue 3, 2024 · pp. 34–49 Read article