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348 articles for “amines”
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Comparison of the Keratinase Gene Sequences of Fast, Slow and Intermediate Feather Degrading Strains of Bacillus licheniformis
Abstract: Feathers are composed of beta keratin which is an insoluble protein resistant to degradation. Bacillus licheniformis has a gene that codes for a keratinase enzyme that hydrolyzes feathers. The DNA sequences of the genes coding for keratinase enzymes of various strains of B. licheniformis were compared. Some strains of the bacteria hydrolyze feathers rapidly, some slowly, and some at an intermediate rate. The mature keratinase enzyme is composed of 274 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 3, 2015 · pp. 1–9 Read article
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The Specificity of Purine Derivatives towards Xanthine Oxidase Enzyme and the Factors Affecting the Enzyme Catalyzed Reaction
Abstract: Xanthine oxidase (XO) is a molybdenum-containing enzyme catalyzing the hydroxylation of a sp2-hybridized carbon in a broad range of aromatic heterocycles and aldehydes. Further, it is a key enzyme in the last two steps of purine metabolism. Thus, the need for an understanding and developing unified reaction mechanism to minimize the amount of accumulated uric acid inside human body has led us to the present detailed study of the reaction …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 2, 2016 · pp. 28–44 Read article
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Virtual Screening of Novel 2-substituted -5-hydroxy-1- (2-methyl-3-morpholinopropyl)-1H-indole-3- carboxamide Derivatives for Estrogen Receptor alpha in AF-2 domain for effective Anticancer Treatment
Abstract: Present manuscript describes designing of novel 2-substituted -5-hydroxy-1-(2-methyl-3- morpholinopropyl)-1H-indole-3-carboxamide derivatives as specific ERα modulators, discuss the selection criteria for 1ERR, several interactions between the ligand and the amino acid residues that would probably elicit fruitful modulation of the receptor. Accordingly, a ligand was observed to yield Gscore of -10.016 which was found comparable with the standard ligand Raloxifene (-11.869). The present work has been designed to discover some novel 2-substituted …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 31–55 Read article
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Description & Prevention of Omicron
Abstract: November 9, 2021, Botswana becomes the first country to recognise it (Nov 11 2021). The new variant (B.1.529) has been represented in 77 countries. Omicron presents 32 changes in spike protein Scribd, restricting the point of interaction with the ACE2 receptor protein. Computational shows and components’ recreation has been applied to investigate the collaboration between the SARS-CoV-2 RBD and the ACE2 receptor. The receptor-binding domain (RBD), which more barely joins …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 4, 2023 · pp. 5–16 Read article
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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An Insilico Study of Isobutrin and Phosphorylase Kinase - A Ray of Hope for Psoriasis Patients – Clinical Hypothesis
Abstract: Psoriasis is a chronic, hyper-proliferative and inflammatory skin disease. Increased levels of the calmodulin-containing enzyme, namely, phosphorylase kinase (PhK), were observed in the human epidermis of the active psoriasis cases. Thus PhK is a potential biomarker for the diagnosis and progression of the skin disease, namely, psoriasis. The search for the potential molecules that could supress the over expression of PhK is underway and any break-through in this direction leads …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 1–8 Read article
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Effect of Lyngbya Confervoides on Children’s Growth
Abstract: Background: The Lyngbya Confervoides grow naturally in a seaside of our country It is one kind of Blue-green alga that is being used for cure of some diseases because it has various significant nutrients such as essential aminoacids, minerals, pigments Methods: The contents of total protein, essential amino acids, minerals and vitamins of Lyngbya Confervoides that is collected in summer were measured. It was examined the effectiveness of the Lyngbya …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 2, 2024 · pp. 01–05 Read article
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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Formulating Pure Natural Polyherbal Hair Dye Preparation for Improved Coloring and Superior Protection Attributes as Compared to Marketed Products
Abstract: AbstractThe commercial synthetic hair dyes include permanent coloring agents like amino compounds (meta-aminophenol, 4-amino-2-hydroxytoluene, etc.), aromatic diamine, polycompounds (para-phenylenediamine), hydric phenols, etc. that precipitates several adverse effects like erythema, skin irritation, skin cancer, loss or damage of hair, etc. In the traditional systems of medicines like Unani, Ayurveda, Homeopathy, and Siddha, the recommended hair dyes are wholly based on plant materials (extracts) and metal oxides (iron oxide, titanium dioxide, etc.). …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 7, Issue 1, 2020 · pp. 1–5 Read article
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Preliminary In Silico Analysis of Choline Monooxygenase and Betaine Aldehyde Dehydrogenase from Suaeda monoica Forssk. and its Expression in E. coli.
Abstract: AbstractIn a tropical country like India, the yield of crop plants is majorly affected by soil salinity and drought. One of the strategies to address this problem is by introducing genes responsible for salinity/drought tolerance in crop plants. Such genes could be identified and isolated from mangrove plants, as they are known to have evolved certain physiological mechanisms to augment saline environments. One such mechanism is the accumulation of Glycine …
Published in Research and Reviews : Journal of Computational Biology · Vol. 9, Issue 1, 2020 · pp. 10–39 Read article
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Acoustical and Thermodynamical Studies of L- Glycine in Buffer Solution of Different pH at 298.15 K
Abstract: The volumetric, viscometric, and acoustical studies are used to investigate the exchange of L-Glycine in a buffer solvent system of different pH at 298.15K within a concentration range of 0.02 to 0.10 molal. L-glycine, being the simplest amino acid, serves as an important model compound for understanding molecular exchanges in biological systems. The effect of pH on the physicochemical properties of amino acid solutions is of considerable significance, as it …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 17, Issue 2, 2026 · pp. 48–58 Read article
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Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System
Abstract: Chiral compounds such as alanine amino acid and s-aminethylated L-cystiene derivatized with chiral reagents such as Marfey's reagents, 2,3,4,6-tetra-O-acetyl-b-D-glucopyranosylisothiocyanate (GITC) and 2,3,4,6-tetra-O-benzoyl-b-D-glucopyranosylisothiocyanate (BGIT), were achieved and separated by optimizing good methods using high performance liquid chromatography. Keywords: Derivatization, amino acid, chiral reagent, HPLCCite this Article Khlafulla Abdulrahim M, Maga Rajab A, Elmessmary Mohamad F. Derivatization of Chiral Compounds with Chiral Reagents and Separation their Isomers by HPLC System. Research & …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 2, 2016 · pp. 39–43 Read article
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Comprehensive In silico Analysis of Single Nucleotide Polymorphisms (SNPs) in Human BDNF Gene
Abstract: Since a number of single nucleotide polymorphisms (SNPs) are associated with the BDNF gene mutations involved in different diseases. Hence, it is important to find out the probable functional SNPs before planning a larger population study. So, to look out for the functional nsSNPs (non-synonymous single nucleotide polymorphisms) in BDNF gene, existing data present in the dbSNP database and different bioinformatics tools like SIFT, PolyPhen, nsSNPAnalyzer, F-SNP, I-mutant, Pymol were …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 8, Issue 3, 2018 · pp. 128–139 Read article
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Attempt on Hydrolysis of Larval Stages of the Black-Soldier-Fly (BSF) (Hermetia illucens) for the Analysis of Utilitarian Properties
Abstract: The enzyme involved hydrolysis is dealing with disintegration of the complex compounds through utilization of enzymes (or the source of enzymes) followed by the reaction with water. The present attempt is dealing with analysis of influence of chemical protein- extraction reaction, and hydrolysis through the use of enzymes (Alcalase, Papain and Pepsin) on the functional-properties, activity of antioxidation and composition of amino-acids of the protein contents of black soldier fly …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 12, Issue 1, 2024 · pp. 1–14 Read article
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Synthesis, Characterization of Novel 5-(Dimethylamino) Naphthalene Sulfonamide Derivatives
Abstract: 5-(Dimethylamino) naphthalene-1-sulphonic acid was synthesized by methylation of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulphonyl chloride were synthesized by the chlorination of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulfonamide derivatives were synthesized by condensation of 5-(Dimethylamino) naphthalene-1-sulphonyl chloride and corresponding primary amines. There chemical structures were confirmed by I. R., 1HNMR and elemental analysis. Keywords: Synthesis, sulfonamides derivatives, 5-(Dimethylamino) naphthalene-1-sulphonic acid, 5-(Dimethylamino) naphthalene-1-sulphonyl chloride Cite this ArticleKhan Asif, Mishra Ritesh, Malvia Hitesh, et al. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 2, Issue 2, 2015 · pp. 1–5 Read article
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Preparation of a Novel Polyherbal Hair Dye Formulation: Better Coloring and Protection Offered as Compared to Marketed Products
Abstract: Synthetic dyes contain permanent coloring agents such as aromatic diamine, amino compounds (4-amino-2-hydrosytoluene, meta-aminophenol, etc.), hydric phenols, polycompounds (para-phenylenediamine) which results in many side effects such as skin irritation, erythrema, loss or damage of hair, and even skin cancer. Dyes obtained from various plant sources are simply available, economical, safe, competent, and rarely have side-effects. In traditional systems of medicines such as Ayurveda, Unani, Siddha, and Homeopathy, the prescribed dyes …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 1, 2020 · pp. 11–15 Read article
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article
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Evaluation of the anti diabetic effects of ethanolic root extract from polyalthania longifora in diabetic rats induced by streptozotin and nicotinamide with considaertion of toxocological aspects
Abstract: The root of Polialthia Longifolia was selected for the evaluation of antidiabetic potential in STZ-nicotinamide induced diabetic rat model.The root extract was extracted by hot percolation using ethanol as a solvent in soxhlet apparatus and the preliminary phytochemical screening was performed and it shows that the ethanolic root extract of Polialthia Longifolia contains alkaloids, glycosides, flavonoids and tannins. Safety profile is essential for the drugs obtained from the plant origin. …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 1, 2024 · pp. 37–50 Read article
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Phytase enzyme and its remarkable effects on chicken health
Abstract: Phytase enzyme catalyzes the hydrolysis of Phytate to mono, di, tri, tetra and penta Phosphate of Myoinositol and Inorganic Phosphate. Cereals, legumes and oilseeds are the main ingredients of animal feed. Phytic acid or phytate is the chief storage form of phosphorus in the feed obtained from these plant sources. Phytate bound important mineral, metal ions and amino acids with it, and in this way it is anti-nutritional element. Simple …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 37–41 Read article
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Synthesis ,Spectral Investigation, Anticancer Study of Azo-Imine Heterocyclic Compounds
Abstract: Many Schiff base reactions are known within a famous series of addition reactions to the azomethine group, where reagents are added to the polarized double bond and the nucleophilic (nucleophilic) reagents attack the carbon atom in the azomethine bond.. An example of this type of reaction is the addition of alkyl halides, which produces quaternary amine salts, which in turn are converted to the secondary amine. These compounds have an …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 1, 2024 · pp. 22–43 Read article