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Research & Reviews: A Journal of Drug Design & Discovery

Synthesis, Characterization of Novel 5-(Dimethylamino) Naphthalene Sulfonamide Derivatives

  1. M. Asif Khan
  2. Ritesh Mishra
  3. Hitesh Malvia
  4. Kamal Jat
  5. Akhilesh Pare

Abstract

5-(Dimethylamino) naphthalene-1-sulphonic acid was synthesized by methylation of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulphonyl chloride were synthesized by the chlorination of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulfonamide derivatives were synthesized by condensation of 5-(Dimethylamino) naphthalene-1-sulphonyl chloride and corresponding primary amines. There chemical structures were confirmed by I. R., 1HNMR and elemental analysis.  Keywords: Synthesis, sulfonamides derivatives, 5-(Dimethylamino) naphthalene-1-sulphonic acid, 5-(Dimethylamino) naphthalene-1-sulphonyl chloride Cite this ArticleKhan Asif, Mishra Ritesh, Malvia Hitesh, et al. Synthesis, characterization of novel 5-(Dimethylamino) naphtha-lene sulfonamide derivatives. Research & Reviews: A Journal of Drug Design & Discovery. 2015; 2(2): 1–5p.
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