Search
137 articles for “Safety and Efficacy”
-
Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
-
Stem Cell Therapy: Advancements, Applications, and Future Prospects in Regenerative Medicine
Abstract: Stem cell therapy has come up as a revolutionary technique in regenerative medicine living up to the promise in treating numerous diseases and injuries. The latest discoveries made in the field of stem cell research such as the introduction of gene editing technology like CRISPR and the creation of the 3D bioprinting process have increased the accuracy and efficacy of stem cell-based therapies. Examples include cardiac regeneration and repair of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
-
Nanotechnology-Driven Drug Delivery: A Comprehensive Review of Current Trends and Future Directions
Abstract: Nanotechnology has revolutionized drug delivery systems, offering profound advancements in precision, efficiency, and targeted therapeutic interventions. This review examines the revolutionary influence of nanotechnology on medical therapies, focusing on advancements, such as precise drug delivery, improved solubility, and responsive treatment systems. These advancements have significantly improved treatment efficacy and minimize side effects, particularly in oncology and chronic disease management. The development of nanoparticles designed for specific cell targeting and environmental …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 15, Issue 1, 2025 · pp. 24–46 Read article
-
Optimization of Robotic Path Planning Algorithms for Autonomous Material Handling Systems
Abstract: For autonomous systems for handling materials (AMHS) to operate as efficiently as possible in industrial and logistical settings, robotic route planning is essential. This study examines many robotic route planning algorithms, emphasizing their use, ways of optimization, and difficulties in material handling systems. To improve the effectiveness, precision, and computational viability of these algorithms, the study also examines a number of optimization strategies, including machine learning, parallelization, heuristic search, and …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 2, Issue 2, 2024 · pp. 15–20 Read article
-
Intermittent Fasting: Exploring the Benefits and Risks of Intermittent Fasting for Weight Loss and Overall Health
Abstract: Perception in Intermittent Fasting: One novel approach for managing weight is intermittent fasting (IF) which is gaining more popularity in recent days. This research investigates advantages and disadvantages of IF with an emphasis on its impact on metabolic processes, cardiovascular health, cognitive abilities, and changes in hormone levels. Methods: A literature review comprising randomized clinical trials, cohort studies, and meta-analyses of peer-reviewed publications was performed. A resolution was obtained by …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 24–29 Read article
-
CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
-
Cosmeceuticals Unveiled Innovation and Efficacy in Skincare Science
Abstract: By combining the terms "Cosmeceuticals" and "pharmaceuticals," the phrase refers to goods that combine the medicinal benefits of pharmaceuticals with the aesthetic benefits of cosmetics. These innovative products do not strictly fall into the categories of either cosmetics or pharmaceuticals but serve as a bridge between the two, offering a unique combination of beauty enhancement and health improvement. Similar to pharmaceuticals, Cosmeceuticals contain active ingredients and compounds that are scientifically …
Published in Recent Trends in Cosmetics · Vol. 1, Issue 2, 2024 · pp. 1–7 Read article
-
Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
-
Self-Healing Thin Films: Paving the Way for Smart, and Sustainable Corrosion Protection
Abstract: Corrosion is one of the serious problems that industries and infrastructures of every type face, ranked among such threats as huge economic losses and concerns to global safety. Recent developments in the area of self-healing thin films make them a really promising innovation for enhancing corrosion protection. This review considers the development, mechanisms, and applications of self-healing thin films. Detailed here are intrinsic and extrinsic self-healing strategies oriented toward chemical …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 22–45 Read article
-
Phytotherapeutic Potential of Melaleuca: An Integrative Review of Phytochemistry and Antimicrobial, Antifungal, Antioxidant, and Antiviral Mechanisms
Abstract: Melaleuca alternifolia and other species of the Melaleuca genus stand out for the broad spectrum of pharmacological properties attributed to their bioactive compounds, such as monoterpenes, sesquiterpenes, flavonoids, and polyphenols. This study aimed to critically review and analyze scientific evidence produced between 2005 and 2025 regarding the antimicrobial, antifungal, antioxidant, and antiviral activities of Melaleuca, correlating its phytochemistry with molecular mechanisms of action. For this purpose, an integrative literature review …
Published in Research & Reviews : Journal of Herbal Science · Vol. 15, Issue 2, 2026 Read article
-
3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
-
A Novel Approach to Fingerprint Authentication Using Histogram Oriented Gradients for Feature Extraction and Machine Learning Convolution Neural Network for Classification
Abstract: With applied biometrics, it is possible to identify a person by examining a feature vector of attributes derived from their physical and behaviour characteristics. In biometrics, fingerprints have become one of the most famous and well known techniques of identification and authentication. In light of technological advancements and safety, fingerprint recognition has been successfully used in a variety of Civil, Defence, and Commercial applications for more than a decade. The …
Published in International Journal of Wireless Security and Networks · Vol. 1, Issue 2, 2023 · pp. 1–12 Read article
-
Nutritional Status, Bioactive Properties & Therapeutic Efficacy of Omega-3 Polyunsaturated Fatty Acids Obtained by Green Synthetic Routes
Abstract: Polyunsaturated fatty acids (PUFAs), particularly omega-3 (n-3) fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are crucial for human health. They support structural brain development, visual acuity, and cardiovascular function, while also exhibiting potent anti-inflammatory, antioxidant, and antimicrobial properties. Historically, marine fish oil has been the primary dietary source of these essential fatty acids. However, escalating concerns regarding ecological environmental impacts, the oceanic bioaccumulation of heavy metal contaminants, …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
-
Developing Techniques for Controlling Different Aspects of Text Generation Such as Tone and Contents
Abstract: Large Language Models (LLMs) have shown excellent text creation quality in Natural Language Processing (NLP). However, LLMs have to satisfy ever-more-complex standards in real-world applications. LLMs are supposed to meet specific user goals, like as mimicking specific writing styles or producing material with poetic richness, in addition to eliminating inaccurate or objectionable content. Controllable Text Generation (CTG) techniques were developed in response to these diverse demands. They guarantee that outputs …
Published in Recent Trends in Programming languages · Vol. 12, Issue 2, 2025 · pp. 34–39 Read article
-
Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
-
Nanotechnology-Based Cosmeceuticals for Anti-Aging and Skin Regeneration
Abstract: Nanotechnology has transformed the cosmetic industry of the cosmeceuticals by allowing the production of sophisticated delivery systems that improve the stability, penetration, bioavailability, and therapeutic efficacy of active ingredients in cosmetics. The present review identifies the value of nanotechnology-based cosmeceuticals in anti-aging and skin regeneration, with special focus on the recent developments in nanocarrier technologies and their use in dermatology. Many nanocarriers have exhibited great potentials in enhancing delivery of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 33–45 Read article
-
Recent Advances in Quality Control and Quality Assurance: Enhancing Pharmaceutical Product Integrity and Compliance
Abstract: The pharmaceutical industry is undergoing a paradigm shift driven by stringent regulatory expectations and the demand for high-quality, safe, and efficacious drug products. Quality Control (QC) and Quality Assurance (QA) serve as the two foundational pillars that ensure pharmaceutical integrity from raw material acquisition through to product release. Traditional QC and QA practices, while effective, have been challenged by complex formulations, biologics, and personalized medicine, requiring innovative methodologies and technologies. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 54–62 Read article