Search
454 articles for “Disorder”
-
Molecular Docking studies of Benzodiazepine Derivatives With GABA(B) Receptor
Abstract: Benzodiazepines (BZDs) are pharmacologically significant compounds that act by binding to GABA A neurotransmitter receptors, subsequently augmenting GABA-induced chloride ion flux, consequently inducing neuronal hyperpolarization. Benzodiazepines are commonly used in the treatment of sleep disorders, anxiety, muscle spasms, seizure disorders, and some forms of depression. The primary inhibitory neurotransmitter, GABA, functions on two types of receptors: the ligand-gated GABA A/C receptors and the G protein-coupled GABA B receptors. These neurotransmitters …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 1–14 Read article
-
Interplay of Thyroid Dynamics in Type 2 Diabetes: A Comprehensive Analytical Study at Government Medical College, Kota, and Affiliated Hospitals
Abstract: Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 1, 2024 · pp. 6–11 Read article
-
A General Review of Mucuna Pruriens W.S.R to its effect on Parkinson’s Disease.
Abstract: Mucuna Pruriens is a very famous drug prescribed in classical ayurvedic science in various disorder of Nervous System including Kampavata .In Clinical Practice ,Physician used Levadopa as a Dopamine replacement agent in controlling bradykinetic symptoms apparent in Parkinson disease so used successfully in treatment of Parkinson disease.Kapikacchu(Mucuna Pruriens) is having Balya, Brimhanaha, Vrishya, and Vatahara properties and is a natural source of L-dopa. So, keeping in views of the degenerative …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
-
Overview On Lauha Rasayana W.S.R. To Rasayogasagar
Abstract: Ayurved is the ancient science which addresses disorders with the natural pharmaceuticals, including those derived from animals, plants, minerals and metals. Rasashastra is a pharmaceutical branch of Ayurved medicine, which developed in mediaeval period and focuses on therapeutic use of metals and minerals. Treatment with using of this metals, minerals, gemstones, animal product and herbal ingredients is known as Rasachikitsa. The key objective of Rasachikitsa is to deliver high-quality, safe …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 11–16 Read article
-
An Extensive Analysis of Computer-Aided Drug Design for Novel Psychotropic and Neurological Substances
Abstract: A comprehensive review of the use of computer-aided drug design (CADD) in the creation of innovative neurologic and neuropsychiatric medications is given in this article. It discusses the challenges in traditional drug discovery approaches and highlights the role of computational methods in accelerating the identification and optimization of drug candidates targeting psychiatric and neurological disorders. The method of finding new drugs has been completely transformed by Computer-Aided Drug Design (CADD), …
Published in International Journal of Brain Sciences · Vol. 1, Issue 2, 2024 · pp. 19–27 Read article
-
Current Perspectives of Prader -Willi Syndrome: A Multisystem Approach
Abstract: Prader-Willi syndrome (PWS) is a genetic disorder with multisystem involvement, caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region from paternal 15q11-q13 deletions (about 60%) or maternal uniparental disomy 15 or both. It is a complex and contiguous gene disorder which affects the multiple systems with many clinical presentations especially hypothalamic insufficiency. The clinical features are characterized by short stature position, developmental delay, cognitive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 42–48 Read article
-
A Comprehensive Review on Long-term Care Policies for Intellectual and Developmental Disabilities
Abstract: Intellectual disability (ID) is a neurodevelopmental difficulty that affects both intellectual functioning and adaptive behaviour. The term IDD describes a broad range of long-term disorders that are caused by either physical or mental deficits. These disorders can influence numerous facets of life, such as self-care, social skills, communication, and education. This condition affects social and practical abilities daily. Conditions like cerebral palsy, Down syndrome, and autism spectrum disorder, Genetic predispositions, …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 2, 2024 · pp. 36–42 Read article
-
Raman Spectroscopy for The Determination of Relative Crystallinity of Carbon Fibers
Abstract: Analogous to X-ray diffraction technique, the light scattering technique discovered by Sir CV Raman has great potential in quantifying the crystallinity of new materials, like the highly crystalline pitch based carbon fibers (NX90 and NX100). For comparison the Raman spectra of polyacrylonitrile based carbon fibers (T700SC) were also recorded. From the Raman spectral analysis, it was found that the pitch based carbon fibers exhibit far far higher degree of crystallinity …
Published in International Journal of Crystalline Materials · Vol. 1, Issue 1, 2024 · pp. 30–38 Read article
-
Multidimensional Impacts on Bryophyllum Pinnatum for the Potential of Obesity: A Review
Abstract: Global public health concerns related to obesity are growing. Several comorbid illnesses, including cardiovascular disease (CVC), gastrointestinal disorders, type 2 diabetes (T2d), joint and muscle disorders, respiratory difficulties, and psychological disorders, are significantly more common in obese patients. The widespread misconception that obesity stems solely from a lack of self-control is gradually losing its stigma as awareness about fat-related issues grows. Instead of synthetic drugs herbal or medicinal plants are …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 42–51 Read article
-
The concept of Sū’-i-mizāj Nukhā and A‘ṣāb
Abstract: The Unani system of medicine provides a holistic understanding of neurological disorders, emphasizing the role of Su’-i-Mizaj (dystemperament) in the spinal cord (Nukhā) and nerves (A‘ṣāb). According to Unani scholars like Ali Ibn Abbas Majusi, disturbances in the mizaj-e-tabai (natural temperament) of Nukhā lead to various neurological conditions, categorized into Istirkhā’ (Flaccidity), Abar Bilqisiya (Bell’s Palsy), Khaddar (Numbness), Tashannuj (Convulsions), and Ra‘sha (Tremors).The most common dystemperament in Nukhā and A‘ṣāb …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 53–57 Read article
-
A Correlational Analytical Study on Smartphone Usage, Physical Activity & Sleep Quality Among Health Science Students
Abstract: Physical activity refers to any bodily movement generated by skeletal muscles that results in the use of energy. It is considered risk factor for various cardiovascular disease leading to higher mortality and morbidity. Sleep is naturally occurring condition marked by a change in consciousness, a significant reduction in sensory activity and the suppression of most voluntary movements. Technological advancements over the past two decades have resulted in rise in smartphone …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 22–32 Read article
-
Interrelationship Between Psychological Stress and Gastrointestinal Physiology: Role of the Gut–Brain Axis
Abstract: The relationship between stress and gut microbiome is a critical area of medical research underscoring the relativity and impact of psychological and emotional states on gastrointestinal (GI) health. This paper investigates the intricate relationship between stress and digestive health by analysing the influence of stress hormones, gut–brain interactions, and psychosocial determinants. Both acute and long-standing stress responses may disrupt normal gastrointestinal activity, affecting motility, secretion, intestinal microbiota, and overall digestive …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
-
Aloe vera: A Review on Its Medicinal Importance
Abstract: Today, one of the main causes of human infection is the antibiotic resistance of bacteria due to the use of antibiotics which causes the emergence and spread of antibiotic-resistant bacterial strains. The search for the discovery of healthy and effective antimicrobial agents continues. Aloe vera can be used for both therapeutic and preventive purposes in the case of a broad range of bacterial infections. Aloe vera is a medicinal plant …
Published in Research and Reviews : Journal of Crop science and Technology Read article
-
To Assessment of the Effectiveness of a Structured Educational Program on Women's Knowledge of Sexually Transmitted Diseases in Rural Areas of Ludhiana, Punjab: A Quasi-experimental Study
Abstract: Background: Maintaining good health is of immeasurable value, as it empowers individuals to lead socially and economically fruitful lives. However, various disorders have the potential to disrupt one's health. Among these, sexually transmitted diseases (STDs) are the most prevalent disorders affecting the reproductive system and other bodily systems, resulting in significant consequences for both families and society. Sexually transmitted diseases (STDs) can be triggered by various microorganisms, including bacteria (like …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 1, Issue 2, 2023 · pp. 19–26 Read article
-
Multiple Sclerosis: A Brief Overview of the Disease, Its Pharmacotherapy
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
-
The Role of Guduchyadi Rasayana In Mental Well-Being – A Review Study
Abstract: In this era, stress is the main etiological factor behind almost every other disease. In 2020, the COVID-19 pandemic led to a notable increase in anxiety and depressive disorders worldwide. This highlighted the critical need for mental health support during such challenging times. Ageing is a biological process characterized universally by natural degeneration, standing out as a significant risk factor for morbidity and mortality. The Oxidative Stress Theory suggests that …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 13, Issue 1, 2024 · pp. 22–30 Read article
-
Review on Elaeocarpus Ganitrus (Rudraksha)
Abstract: The seed of Elaeocarpus Ganitrus, also known as Rudraksha, is renowned for its electromagnetic characteristics. Recent scientific research has demonstrated that this seed possesses natural electromagnetic properties which can effectively treat various chronic diseases. This study focuses on the phytochemical screening and thin layer chromatographic analysis of the extract obtained from Elaeocarpus Ganitrus seeds, which belong to the Elaeocarpaceae family. Bombay, and is commonly grown as an ornamental tree in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 8–15 Read article
-
In Silico Investigation of 2,3-Dihydrobenzofuran from Centella asiatica: A Possible Pioneer in the Management of Tetanus
Abstract: Objective: Tetanus toxin (TeNT) is a neuroprotein toxin, the most toxic known. They have three functional domains and are structurally similar. They possess an N-terminal catalytic section (light chain), an internal domain for heavy-chain translocation (HN domain), and a C-terminal receptor binding domain for the heavy chain (Hc domain or RBD). Tetanus, an acute nerve-affecting disease, is provoked by a toxin-producing bacterium called Clostridium tetani. This bacterium is environmental, Gram-positive, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 19–30 Read article
-
Climate Change & Its Effects on Human Health: A Comprehensive Review
Abstract: Anthropogenic climate change has wide-ranging effects on human health and is a significant worldwide concern. This thorough analysis highlights the connections between environmental, social, and biological elements as it explores the complex implications of climate change on health. Numerous health consequences, such as vector-borne infections, heat-related illnesses, respiratory issues, and mental health issues, can be impacted by shifting precipitation patterns, rising temperatures, and a rise in the frequency of extreme …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 16–20 Read article
-
Targeting Dystrophin Restoration and Neuroprotection in Duchenne Muscular Dystrophy: Insights from Withania somnifera
Abstract: Duchenne muscular dystrophy is a genetic disorder. This disease affects men more common than women. Main objective of the present study was to identify the naturally active phytocompounds from Withania somnifera (Ashwagandha). Ashwagandha has a great value in the field of Ayurveda and Indian medicine and is used for treating muscular and neurological disorders. Toxicity prediction, molecular docking, statistical information, drug illness prediction, and Absorption, distribution, metabolism, excretion, and toxicity …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 64–84 Read article