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225 articles for “Controlled Release”
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Design and Evaluation Cefaclor Microspheres for Bioavailability Enhancement
Abstract: This study attempted to formulate microspheres for oral administration of Cefaclor by using different polymers like Hydroxypropyl methylcellulose (HPMC) K4M, (HPMC) K15M and Ethylcellulose (EC) which increases the gastric residence time and thereby the bioavailability. Solvent evaporation method was found to be the best due to its ease of fabrication without compromising the activity of the drug. Cefaclor is a second-generation cephalosporin antibiotic used to treat certain ear, lung, skin, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 3, 2019 · pp. 39–48 Read article
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Production Control Mechanisms and POLCA Performance in a Divergent Production Line
Abstract: Production control mechanism is a critical element in today’s production situation, where production systems compete on quick response and resource efficiency. The purpose of a production control mechanism is to define the best time to release material and orders. POLCA is a simple production control mechanism that on one hand tries to reduce throughput time and on the other hand helps the manager to control work-in-process inventory. In addition to …
Published in Journal of Production Research & Management · Vol. 2, Issue 1-2-3, 2012 · pp. 26–39 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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Review On: Liquid Crystal Cream for Topical Drug Delivery
Abstract: A Liquid crystal creams represent a novel approach in skincare formulations, leveraging the unique properties of liquid crystal technology to improve skin hydration and barrier function. An overview of current developments in liquid crystal cream formulations is given in this article, with an emphasis on the benefits they offer for skincare and their composition and structure. Liquid crystal creams mimic the lipid bilayers of the skin, offering enhanced compatibility and …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 1–8 Read article
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Effect of Compression Ratio on Petro-DEE Fuelled HCCI Engine
Abstract: In compression ignition engines, soot-NOx paradox is extremely challenging issue, which remains to be resolved. Homogeneous charge compression ignition is a new combustion concept that gives benefits such as diesel like efficiency and resolves the problem of high level of NOx and PM simultaneously. It gives very high rate of heat release which cannot be easily controlled. The present work deals with development of HCCI engine and experimental investigations on …
Published in Journal of Automobile Engineering and Applications · Vol. 2, Issue 3, 2015 · pp. 1–11 Read article
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Formulation and Evaluation of Curcumin Loaded Transferosomal Nasal In-Situ Gel for Alzheimer’s Disease
Abstract: Objective: To develop a novel delivery of curcumin by formulating its transfersome into nasal in situ gel. Methods: Curcumin transfersomes were prepared by thin film hydration method. Optimization of the formulation was performed using Design Expert software. Formulation and characterization of optimized batch of curcumin transfersomes were performed. The nasal in situ gel was prepared by incorporating the optimized transfersome. Results: The pH, drug content, in-vitro drug release profile and …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 2, 2019 · pp. 19–31 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Advancements in Solubility Enhancement Through Liquisolid Compact Technology: A Comprehensive Review
Abstract: The study examines Liquisolid Compact Technology as an innovative approach for improving the bioavailability and solubility of drugs that are poorly soluble in water. Liquisolid systems, comprising solid carriers and liquid drugs, offer advantages such as improved drug release and bioavailability, reduced manufacturing costs, and controlled drug delivery. The technique involves dissolving or suspending the drug in non-volatile solvents, adding carrier materials, super disintegrants, and coating materials, and then compressing …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 25–34 Read article
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A Review on the Interconnection Between Drug Design and Controlled Drug Delivery Systems
Abstract: Drug discovery and delivery are two branches of science that have historically developed as independent areas of discovery – one focused on optimizing the properties of molecules for biological activity, and the other on controlling the rate, site, and duration for drug release. However, in contemporary pharmacy, these two areas have merged into a single integrated approach – where drug discovery and delivery strategies co-influence each other at each point …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 47–52 Read article
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Design and Implementation of Agricultural Spraying Drone
Abstract: In this brief an attempt has been made to develop an agricultural drone to spray pesticides in an agricultural farm. In India, agriculture is one of the key economic sectors. Crop production rates are influenced by factors such as temperature, moisture content, rainfall, etc. The field of husbandry is also influenced by other elements, such as pests, complaints, diseases, etc., which can be managed by giving crops the right care. …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 1, 2023 · pp. 28–33 Read article
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A System of Smart Irrigation with Precise Pesticides and Fertilizers Integration in Waterflow
Abstract: The paper extensively discusses the hardware components essential for the system, including the Arduino Uno microcontroller, soil moisture sensors, water pumps, and dispensers for fertilizers and pesticides. Key IoT components, such as an IoT module (e.g., ESP8266), facilitate data transmission and remote control via a dedicated mobile application. A pivotal aspect of this research is the development of the mobile application, which empowers users to monitor soil moisture levels, control …
Published in Journal of Electronic Design Technology · Vol. 14, Issue 3, 2023 · pp. 1–10 Read article
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Clone-Specific Drug Delivery Systems: Targeted Approaches and Future Clinical Applications
Abstract: Clone-specific drug delivery systems represent a transformative frontier in personalized medicine, addressing the longstanding challenge of clonal heterogeneity within diseases such as cancer, infectious diseases, and autoimmune disorders. Traditional drug delivery platforms often fail to discriminate between pathogenic and healthy cells, leading to systemic toxicity and reduced therapeutic efficacy. In contrast, clone-specific systems aim to selectively target and eliminate disease-driving cellular clones based on unique molecular signatures, thereby improving treatment …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 21–29 Read article
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PLC & SCADA-based Automation in Boiler Systems Enhancing Energy Efficiency: A Review
Abstract: Data acquisition and supervisory management system utilizing a programmable logic controller. PLC, SCADA, and sensors are used in the design and development of a boiler automation system. Using communication wires, the PLC and SCADA were connected. The paper's introductory section focuses on supplying the boiler with inputs at the necessary temperature to consistently maintain a specific boiler temperature. the numerous steps needed to transition from a traditionally controlled boiler to …
Published in Journal of Thermal Engineering and Applications · Vol. 10, Issue 1, 2023 · pp. 20–25 Read article
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Advancement in Biodegradable Equipment for Flexible and Sustainable Electronics
Abstract: Biodegradable electronics are a quickly developing area focused on reducing the environmental impact of traditional electronic waste by using materials that can break down naturally after use. These devices use eco-friendly polymers, nanocomposites, and bio-based materials that maintain electrical function temporarily before safely decomposing. Recent developments show the potential of plant-based polymers, conductive biodegradable composites, and transient materials that support flexible and wearable applications without causing long-term harm to the …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 32–37 Read article
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UV Spectrophotometric Method for the Estimation of Etoposide and its Application in Study of Polymeric Nanoparticles
Abstract: A rapid, economical, accurate and simple UV spectrophotometric method was developed for quantification of etoposide in bulk and pharmaceutical formulation and its application in the study of polymeric nanoparticles. The samples were quantified at 284 nm in both methanol and phosphate buffer saline (PBS) at pH 7.4. The method was linear (r2 > 0.99) over the range of 20–100 μg/ml, precise (RSD < 5%), accurate (recovery values close to 100%), …
Published in Trends in Drug Delivery · Vol. 3, Issue 1, 2016 · pp. 46–51 Read article
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Numerical Modeling of Drug Release from HPMC Carriers with Erosion
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} Numerical modeling of drug release kinetics from hydroxypropyl methylcellulose (HPMC) carriers is investigated. Recently a comprehensive model describing the controlling processes of this kinetics (water uptake, drug …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 1, 2011 · pp. 30–35 Read article
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Mean User Data Throughput Assessment From A Public UMTS/HSPA Network
Abstract: The demands of packet data communication and applications have resulted in several improvements over the original WCDMA Release 99. The downlink was improved in Release 5 with high speed packet data access (HSDPA), which provided high speed shared channel with fast link adaptation and scheduling, hybrid ARQ, and a short 2 ms transmission time interval (TTI). The corresponding uplink enhancements were done in Release 6 with high speed packet data …
Published in Recent Trends in Electronics Communication Systems · Vol. 2, Issue 2, 2015 · pp. 1–6 Read article
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The Interaction of Extracellular Matrix and Growth Factors
Abstract: The extracellular matrix (ECM) regulates cell behavior by influencing cell proliferation, survival, shape, migration and differentiation. ECM assembly is regulated by the 3D environment and the cellular tension that is transmitted through integrins. The hematopoietic microenvironment is a complex structure in which stem cells, progenitor cells, stromal cells, growth factors, and ECM molecules each interact to direct the coordinated regulation of blood cell development. Hematopoietic growth factors are any of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 6, Issue 3, 2016 · pp. 9–23 Read article
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Efficacy of New Fungicides in Controlling Powdery Mildew of Sweet Gourd
Abstract: This experiment was conducted at the Plant Pathology Division, Regional Agricultural Research Station (RARS), Jamalpur, Bangladesh during 2025 of Rabi & Kharif-1 seasons to find out the effectiveness of new fungicides against Powdery mildew disease of sweet gourd. Twenty (20) new fungicides viz. Acrozet 50 WP, Qingdao GBW, Hea 10 FC, Top star 32.5 SC, Nila 80 WP, Soazeb 72 WP, Safezeb 80 WP, Canvas 32.5 SC, Pyzim 50 WP, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 134–142 Read article