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206 articles for “ACE 2”
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Non-Invasive Diabetes Test by Breath Analysis using Semiconductor Gadget
Abstract: AbstractNon-invasive detection of diabetes via acetone sensing using nanostructure semiconductor metal oxides (SMO) is an alternative fast and direct method to invasive blood analysis. It is a reliable and accurate technology. Of late, graphene and graphene oxides are promising nanomaterials for acetone sensing.Keywords: Non-invasive diabetes; Breath analysis, Acetone sensing; Nano materials.Cite this ArticleSurajit Kumar Hazra, Sukumar Basu. Non-Invasive Diabetes Test by Breath Analysis using Semiconductor Gadget. Journal of Semiconductor Devices …
Published in Journal of Semiconductor Devices and Circuits · Vol. 7, Issue 2, 2020 · pp. 20–22 Read article
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Effect of Spray Pyrolysis on the Properties of Chemically Sprayed CuO:Al Thin Films
Abstract: AbstractCuO:Al thin films were grown from 50 ml of spray solution on glass substrates by chemical spray at Ts=400°C using solution spray doping percentages of 0, 4, 5 and 6%. Copper acetate and aluminium chloride were used as Cu and Al sources, respectively. Independent of solution spray rate, the crystallites in CuO:Al films grow preferentially in the (201) plane, parallel to the substrates. The spray pyrolysis solution are using different …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 4, Issue 1, 2017 · pp. 1–5 Read article
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A Review on the Intelligent Schemes for Automatic Generation Control in Modern Power System
Abstract: AbstractAutomatic generation control (AGC) is one of the important control problems in the design and operation of interconnected power system, and is gaining popularity today due to the growing size, varying structure, upcoming renewable energy sources and new uncertainties, and complexity of power systems. AGC system requires increased intelligence and flexibility to guarantee balance between load and generation. The modern AGC systems surely must be intelligent, and should be capable …
Published in Journal of Advancements in Robotics · Vol. 4, Issue 3, 2017 · pp. 1–4 Read article
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Neurological Manifestations of COVID 19 infection-An Update
Abstract: AbstractThis article focuses on the neurological disorders related to Covid 19 infection based on studies reported from china, Italy and other countries. The virus attaches to the Angiotensin Converting enzyme Receptor which is widely distributed in the body including nervous system. Virus can effected the nervous system by direct neurotropic effects, Immune mediated damage or due to secondary involvement as a part of multi organ dysfunction. Covid 19 Infection is …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 2, 2020 · pp. 7–11 Read article
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Anti-nociceptive Potential of Scurrula parasitica: An Unexploited Parasitic Plant
Abstract: Scurrula parasitica (Loranthaceae) is an herbaceous growing shrub parasitic on Dendrophthoe falcata (Loranthaceae) which is itself parasitic on Mangifera indica (Anacardiaceae). Scurrula parasitica is distributed throughout the western ghat region of Maharashtra, some parts of Uttar Karnataka and Tamil Nadu. Genus Scurrula comprising of around 91 species, however, only S. ferruginea, S. atropurpurea, S. fusca have been investigated systematically. No such pharmacological and phytochemical data are available on the plant …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 3, Issue 1, 2013 · pp. 4–8 Read article
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Analysis of Anti-psychotic Drug Penfluridol in Human Plasma by HPLC and MS/MS
Abstract: Penfluridol is a new long-acting neuroleptic drug known to be used widely for treating psychotic conditions. An internal standard was employed, which was penfluridol D7 (IS). The analyte and the IS were separated on a Phenomenex Kinetex C18, 5µm 100A, 100*4.6mm column using acetonitrile (40:60, v/v) as the mobile phase and 5 mM ammonium formate as the stationary phase. The retention time of Penfluridol and Penfluridol d7 was set at …
Published in Trends in Drug Delivery · Vol. 9, Issue 2, 2022 · pp. 36–45 Read article
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Development of Primer as a Value Added Product from Waste PET
Abstract: Polyethylene terephthalate was depolymerized by two different chemical recycling techniques i.e. glycolysis and aminolysis. Glycolysis is carried out with Zinc hydroxide and with conventional catalyst i.e. Zinc acetate for the comparable yield of the monomer. Glycolysis is carried out with ethylene glycol whereas aminolysis is done with ethanolamine. Products obtained from both the techniques namely Bis(2-hydroxyethyl) terephthalate (BHET) and Bis(2-hydroxyethyl) terephthalamide (BHETA) have different chemical structure but have hydroxyl functionality …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 2, Issue 3, 2015 · pp. 5–16 Read article
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Evaluation of Antioxidant and Cytotoxic activities of Mycelia Biomass and Culture broth of three Edible Mushrooms, Morchella conica, Hericium erinaceus and Pleurotus florida Grown in Submerged Culture
Abstract: Mycelia biomass of three edible mushrooms namely, Morchella conica, Pleurotus florida and Hericium erinaceus were grown as submerged culture in potato dextrose broth supplemented with yeast extract, potassium dihydrogen orthophosphate and magnesium sulphate. The mycelia biomass was extracted with 70% ethanol and culture broth with ethyl acetate. The solvents were evaporated to dryness at low temperature using a rotary vacuum evaporator and the residues thus obtained were used for the …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 37–50 Read article
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A Concurrent Estimation of Phytoconstituents Piperine, Quercetin and Kaempferol Present in Siddha Polyherbal Formulation Kabasara Kudineer by Rp-Hplc
Abstract: A straightforward, accurate, and precise technique was developed and validated for the simultaneous determination of Quercetin, Kaempferol, and Piperine in the polyherbal formulation Kabasura Kudineer. The sample was chromatographed using a C18 column (150x4.6mm, 5u) with a mobile phase composed of Acetonitrile and Ortho phosphoric acid in a 45:55 ratio, flowing through the column at a rate of 1ml/min. The detection wavelength for Quercetin, Kaempferol, and Piperine was set at …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 1–9 Read article
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Mercury-induced Biochemical Changes in Perna viridis Exposed in Chronic Toxicity Test
Abstract: In the present study, the Asian green mussel, Perna viridis, was exposed to 50, 75, 113, 160 and 253 µg/L Hg concentrations under chronic toxicity for the assessment of biochemical biomarkers. Higher levels of glutathione S-transferase (GST), reduced glutathione (GSH), lipid peroxidation (LPO) and lower levels of protein, catalase (CAT) and acetylcholinesterase (AchE) were found. The values were found to be significant at P < 0.01. This study suggests that …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 15–22 Read article
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Synthesis and Evaluation of Chalcone Derivatives and Schiff bases derivatives as Antibacterial
Abstract: AbstractSix substituted chalcones have been synthesized by condensing benzaldehyde derivatives with acetophenone in dilute ethanolic sodium hydroxide solution at room temperature according to Claisen-Schmidt condensation. In addition, four of Schiff bases have been prepared via imine condensation between substituted benzaldehyde firstly with (3) 2-aminophenol, secondly, with phenylhydrazine. Moreover, study the efficient of synthesized compounds as antibacterial agents were evaluated. The structures of the synthesized compounds were confirmed by the melting …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 9, Issue 3, 2018 · pp. 1–7 Read article
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Excoecaria agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies
Abstract: Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
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Comparison between Total Hip Replacement and Bipolar Hip Replacement
Abstract: Purpose: A prospective, randomized study was performed to compare the clinical and functional outcomes at 5–15 years of follow-up in two groups of patients treated with either bipolar hip replacement or total hip replacement (THR). Materials and Methods: A total of 509 patients with either femoral neck fractures, degenerative arthritis, systemic arthritic diseases, avascular necrosis of the femoral head or pathologic fractures underwent surgery between May 2000 and June 2012. …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 2, 2019 · pp. 12–17 Read article
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Electronic Safety Locker with SMS Alert
Abstract: The title of the project is electronic security locker. It'll be valuable for society, bank as well as industry. The outline of this venture is that the locker has five level passwords. Administrator needs to split all of five secret words; this can be the primary security. In the event that client cannot effectively break five attempts at that point entirety framework can be hang and buzzer on until ace …
Published in Journal of Open Source Developments · Vol. 5, Issue 3, 2018 · pp. 17–20 Read article
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Friendly and Efficient Synthesis of Chalcone Derivatives under Solvent-Free Condition
Abstract: A series of various chalcone derivatives were synthesized using solvent free technique by grinding different substituted benzaldehyde, acetophenone and NaOH pellets at room temperature, and same reactions were carried out under solvent condition (50% EtOH). The reaction time needed to synthesize desired chalcones was 15–45 min; and 13 h stirring in the presence of solvent. All compounds were identified by comparison of their melting points with that of the substrates; …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 6, Issue 1, 2016 · pp. 17–24 Read article
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Investigation of Residual Stress, and corrosion behavior of AA6082/Al 2 O 3 /C/ Si 3 N 4 Composite Material
Abstract: The main objective of the current study was to create AA6082/ Al2O3/C/Si3N4 Composite Material by the use of stir casting. The properties of the AA6082/ Al2O3/C/ Si3N4 Composite Material shown a significant improvement, with a micro-hardness rise of 13.5% and a residual stress decrease of 60%. As the testing parameters were increased, the residual stress of the AA6082/ Al2O3/C/ Si3N4 Composite Material rapidly decreased from -65MPa to -15MPa. An electromagnetic …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1104–1109 Read article
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A Comprehensive Review on Chitosan Anticancer Property
Abstract: Chitosan, a hydrophilic, natural amino polysaccharide derived from chitin on alkaline de-acetylation. Chitosan is a nontoxic, biocompatible, antibacterial and biodegradable polymer. The biological activities of chitosan are mainly depending on the water solubility nature and also the solubility in other solvents. The primary amino group present in the chitosan is the key functional groups which is mainly responsible for its bioactivities. The biological activities of antimicrobial, antioxidant and anticancer properties …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 2, 2020 · pp. 1–7 Read article
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Methodologies for in silico and in vitro Test of Biphenylalanine Compounds as Potential HIV-1 gp120 Attachment Inhibitors
Abstract: We postulate that biphenylalanine and its derivatives are propitious candidates to inhibit the binding of HIV-gp120 to CD4 T-cell. Many biphenylalanine derivatives are synthesized chemically and also prevailing in nature. We have proposed atom- and bond-based 2D TOMOCOMD-CARDD approach to identify the best derivative. Moreover, according to our proposition, the principal law simulated from in silico interaction of gp120 with CD4 can be tested by ELISA in vitro. Furthermore, the …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 2, Issue 3, 2015 · pp. 38–42 Read article
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A Novel Analytical Method for the Simultaneous Estimation of Remogliflozin and Metformin Hydrochloride
Abstract: Specific and novel strategy has been improved for assessment of Remogliflozin and Metformin hydrochloride in mass and plan and cleaning tests by UPLC-PDA. The scientific method was the phosphate Buffer (pH: 4.5): Acetonitrile, (60:40%, v/v) utilizing the spherisorb C18, 5 µm, 4.6 mm×150 mm insightful segment with investigation season of 5 min. The progression of versatile stage through section was 1.0 ml/min. The test volume was 10 µl. The discovery …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 7, Issue 3, 2020 · pp. 1–15 Read article