Search
1957 articles for “activation” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
-
Review on Unveiling the Shadow of Hyperpigmentation
Abstract: Natural products offer promising solutions for treating skin pigmentation disorders due to their non-toxic properties and effective mechanisms of action. Studies highlight their safety and efficacy through methods such as cytotoxicity tests, tyrosinase activity assays, and melanogenesis inhibition evaluations. Advanced delivery systems like liposomes and nanoparticles further enhance their performance by improving solubility and skin penetration. Skin pigmentation disorders, influenced by factors such as UV radiation, hormonal changes, and inflammation, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 59–66 Read article
-
Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
-
IoT Integration in Logistics Network System–A Glance
Abstract: Transportation and logistics play a most essential role in operations and supply chain management applications. As a medium, it makes it easier for people, things, and products to move from one place to another. At one stage of the supply chain, from 90% to 95% of produced goods are transported in containers. Additionally, the global consumer class is predicted to grow by 35% to 40% by 2030, increasing the demands …
Published in International Journal of Industrial and Product Design Engineering · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
-
Neuro-Rehabilitation Reimagined: A Cross-Cultural Paradigm Integrating Immunotherapeutics and Multidimensional Analytics in Pediatric Cerebral Palsy
Abstract: Researchers performed multidimensional data analysis on the clinical records of 1,586 cerebral palsy pediatric patients to investigate the rehabilitative benefits of immunotherapy and the advantages of blending Traditional Chinese Medicine with Western treatments. A multi-center, prospective cohort study established a standardized system for data gathering that included clinical baseline databases along with treatment protocols and follow-up information. Baseline data analysis showed substantial patient diversity across clinical types and TCM syndromes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 67–84 Read article
-
Effectiveness of Sustainable Design and Costing Practices in Construction: A Cross-Sectional Survey of Professionals’ Roles Towards Resource Conservation
Abstract: Climate change and the continuous depletion of natural resources have significant implications for the built environment. Sustainable construction has thus become topical, with measures being widely discussed on how to integrate it into proposed product design development, necessary to ensure resource conservation. This study evaluates the role of built environment design and costing professionals in sustainable construction, exploring their contributions towards resource conservation, and their effectiveness in implementing sustainable practices …
Published in International Journal of Industrial and Product Design Engineering · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
-
Green Remediation and Eco-Sustainability: Enhancing Human Wellness and Welfare Through Planned Integration of Eco-Composites
Abstract: Green remediation involves assessing the complete environmental impact of implementing a solution and integrating choices to optimize the overall environmental gains from cleanup actions. This introductory guide delineates the principles of green remediation and explores possibilities for diminishing the environmental footprint of cleanup activities over the course of a project. Conserving environment is a prime concern soliciting our attention for making the external environment, including the physical, natural, social and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 242–251 Read article
-
Implementation of a Smart Helmet for Safety and Monitoring using IoT and Sensor Integration
Abstract: The Smart Helmet is a revolutionary safety helmet that incorporates advanced technology to advanceuser protection, connectivity, and real-time awareness. The helmet, intended for motorcyclists,cyclists, and workers, comes with integral sensors for impact sensing and alcohol level checking, GPS tracking, Bluetooth voice communication, and monitoring of vital signs. The features combine to provide smart accident detection and avoidance, hands-free talk, and real-time location tracking. In case of an accident or dangerous …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 2, 2025 · pp. 15–25 Read article
-
Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
-
Cis-9, Trans-11 Conjugated Linoleic Acid in Milk: Natural Sources, Nutritional Advantages, and Potential Health Benefits
Abstract: Cis-9, trans-11 conjugated linoleic acid (CLA) is the most common type of CLA found in milk. It has gained a lot of attention because it may have several health benefits. This bioactive lipid is primarily derived from ruminal biohydrogenation of dietary linoleic acid and endogenous synthesis in the mammary gland via Δ9-desaturase activity. Various dietary and management strategies influence CLA concentrations in milk, including forage composition, lipid supplementation, and grazing …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
-
Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
-
ANN Approach to Forecasting the Strength of Nano Silica Incorporated Geopolymer Composite
Abstract: Coal and steel industry by-products, such as fly ash (FA) and blast furnace slag (GGBS), have gained significant attention as precursors for geopolymer concrete (GPC) due to their high aluminosilicate content, offering a sustainable alternative to conventional cement. Nano silica (NS), recognized for its exceptional pozzolanic activity and ability to refine microstructure, has shown potential to enhance the mechanical and durability properties of GPC. This study investigates the influence of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 267–278 Read article
-
A Study on the Impact of Paracetamol on Male Reproductive System: A Mini Review
Abstract: Paracetamol, a widely used analgesic and antipyretic, has been studied for its potential effects on the male reproductive system. Paracetamol is a medication commonly used to relieve mild to moderate pain. Research suggests that prolonged or high-dose use of paracetamol may adversely affect male fertility by disrupting hormone regulation, impairing sperm production, and reducing testosterone levels. Studies have shown that paracetamol can interfere with the hypothalamic-pituitary-gonadal axis, leading to changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 43–51 Read article
-
CredBud: The Ultimate Student Platform
Abstract: In the rapidly evolving educational landscape, effective management of student performance, attendance, and engagement is essential for fostering accountability, motivation, and academic growth. Addressing the limitations of traditional methods, CredBud introduces an innovative digital platform designed to revolutionize academic management. This secure, user-friendly ecosystem empowers both students and faculty to enhance efficiency and collaboration. CredBud’s key features include a credit allocation and grading system to monitor academic progress, a theoretical …
Published in Journal of Microcontroller Engineering and Applications · Vol. 12, Issue 2, 2025 · pp. 1–9 Read article
-
Blockchain-Assisted Electronic Voting: A System Design Perspective
Abstract: Voting plays a vital role in upholding democratic principles by allowing individuals to express their preferences and take part in shaping the decisions that affect their lives. Despite its importance, traditional voting systems—whether manual or digital—continue to encounter major obstacles. These include a lack of transparency, declining voter turnout, vulnerability to fraud, and concerns around manipulation. While digital voting platforms offer a modern alternative, they often face skepticism due to …
Published in Journal of Electronic Design Technology · Vol. 16, Issue 2, 2025 · pp. 9–16 Read article
-
Catalytic Pyrolysis of Polymer Composites
Abstract: The increasing accumulation of polymer-based waste, including polymer composites, is causing degradation of environment and hence becoming a big issue. In the present paper, the researchers have taken up the question and tried to find the solution in the form of catalytic pyrolysis which can be opted as potential substitute. By the application of catalytic pyrolysis, it is getting checked and analysed that whether application will lead to transformation of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 379–389 Read article
-
The Rising Burden of Heart Attacks: Causes, Trends, and Prevention Strategies
Abstract: Heart attacks, or myocardial infarctions, remain a leading cause of morbidity and mortality worldwide, with their incidence rising steadily across diverse populations. This review explores the increasing prevalence of heart attacks, emphasizing traditional risk factors, such as poor diet, physical inactivity, smoking, and medical conditions like hypertension, diabetes, and hyperlipidemia. It also highlights emerging risk factors, such as chronic infections, pollutants, substance abuse, and the lasting cardiovascular effects of COVID-19. …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 1–11 Read article
-
A prospective investigation into seroma monitoring and skin flap anchoring following Mastectomy
Abstract: Breast cancer remains a significant global health challenge, often necessitating life-saving mastectomy surgeries. However, post-mastectomy complications—such as seroma formation and skin flap necrosis—can still impact a patient’s recovery and overall quality of life. This prospective study examines the effectiveness of seroma monitoring and skin flap anchoring following mastectomy in reducing these problems. Few prospective studies addressing these particular concerns were found in a thorough literature assessment. To fill this void, …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 Read article
-
Physical and Mechanical Properties of GGBS Based Geopolymer Concrete with the Inclusion of Metakaolin
Abstract: The use of ecologically friendly materials in the production of concrete is a significant and pertinent development in the global movement for sustainable construction. Geopolymer concrete (GPC) has gained popularity as an alternative to conventional Portland cement (OPC)-based concrete due to its utilisation of ground granulated blast furnace slag (GGBS), fly ash, and metakaolin, among other industrial by-products. The production of geopolymer concrete addresses serious environmental problems and contributes to …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 261–266 Read article
-
Hiv/aids pandemic and national security
Abstract: The Acquired Immune Deficiency Syndrome (AIDS) is disease caused by the Human Immunodeficiency Virus (HIV), whose clinical manifestation results in the failure of the Immune system to function normally to protect the individual from being attacked or threatened by diseases. The world's attention was drawn to the first observed case in 1981 and a second in 1982 in two different socio-cultural and economic settings and the world then fails to …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 53–66 Read article
-
Decoding Innate Immunity: Mechanisms, Components, and Clinical Implication
Abstract: Innate immunology represents the body's first line of defense against pathogens, acting as a rapid, non-specific response to a wide array of microbial invaders. This part of the immune system depends on pattern recognition receptors (PRRs) to identify pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), leading to the activation of immune cells such as macrophages, dendritic cells, and neutrophils. The innate immune system also plays a crucial role …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article