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1775 articles for “conditions”
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Crispr Cas – Revolutionizing Modern Therapies and Beyond
Abstract: CRISPR-Cas technology has emerged as a transformative tool in modern molecular biology, revolutionizing both fundamental research and clinical applications. This RNA-guided gene-editing system enables precise and efficient genomic modifications, offering unprecedented potential for addressing genetic disorders, infectious diseases, and oncological conditions through innovative therapeutic interventions. The inherent specificity and programmability of CRISPR-Cas systems have facilitated breakthroughs in diverse fields, including precision medicine, regenerative therapies, and immuno-oncology. Beyond its therapeutic applications, …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 25–38 Read article
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Implementation of a Smart Helmet for Safety and Monitoring using IoT and Sensor Integration
Abstract: The Smart Helmet is a revolutionary safety helmet that incorporates advanced technology to advanceuser protection, connectivity, and real-time awareness. The helmet, intended for motorcyclists,cyclists, and workers, comes with integral sensors for impact sensing and alcohol level checking, GPS tracking, Bluetooth voice communication, and monitoring of vital signs. The features combine to provide smart accident detection and avoidance, hands-free talk, and real-time location tracking. In case of an accident or dangerous …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 2, 2025 · pp. 15–25 Read article
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Single-Cell Genomics and its Impact on Understanding Cellular Heterogeneity
Abstract: Single-cell genomics has transformed how we study the differences between individual cells, helping scientists uncover the detailed variety within tissues that traditional methods could not reveal. Traditional methods, such as RNA sequencing, average gene expression across many cells, thereby missing subtle yet important cellular variations. Single-cell technologies, such as single-cell RNA sequencing (scRNA-seq), DNA sequencing, and epigenomics, allow researchers to study individual cells in extraordinary detail like never before. This …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 1–5 Read article
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AI and IoT in Sustainable Agriculture: A Review
Abstract: Artificial Intelligence (AI) and Internet of Things (IoT) integration have transformed the world of sustainable agriculture, presenting new ways of resource optimization, increasing crop yields, and making environmental sustainability more accessible. The current literature review analyzes the applications of AI and IoT in three significant agricultural systems: aquaponics, hydroponics, and poultry farming. By critically analyzing recent studies, this paper emphasizes how deep learning- enabled computer vision techniques allow for the …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 2, 2025 · pp. 32–45 Read article
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Enhancing Campus Security Using IOT Sensors
Abstract: Security within university campuses continues to be of paramount importance to learning institutions, with conventional CCTV systems tending to be slow and prone to operator errors. The project discusses an IoT system with Flutter, ESP32-CAM, flame and noise sensors, and buzzer for an efficient real-time surveillance and timely emergency response. The system can detect abnormal conditions like loud noises and fire risks, sending alarms and enabling live video streaming over …
Published in Journal of Instrumentation Technology & Innovations · Vol. 15, Issue 2, 2025 · pp. 26–31 Read article
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Exploring the Role of Small Dense LDL-C and Paraoxonase-I Activity in Lipid Profile Alterations in Postmenopausal Women: Evidence from a Population-Based Study in Punjab, India
Abstract: Background: After menopause, women face a higher risk of cardiovascular disease (CVD) because hormonal changes impact how their bodies process fats. This study aimed to explore the relationship between small dense LDL cholesterol (sdLDL-C), lipid profile, PON1 levels, thyroid function, CBC parameters, and cardiovascular risk in postmenopausal women (45–60 years) in Punjab, India. sdLDL-C is more atherogenic than larger LDL particles, while PON1, linked to HDL, offers heart protection. Thyroid …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 45–49 Read article
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Assessing the impact of lifestyle factors on autoimmune risk and survival outcomes: A Population-based Study
Abstract: This study investigated the interplay between lifestyle factors and genetic regulation in autoimmune diseases, focusing on the role of human T-cell metabolic and proliferative control through C-REL gene transcription. This study combined CRISPR-Cas9 manipulation of C-REL in human T-cells with a longitudinal cohort of 100 adults (autoimmune patients and controls), investigating metabolic and proliferation dynamics via flow cytometry and assays. It assessed lifestyle impacts through surveys and medical records, ensuring …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Cis-9, Trans-11 Conjugated Linoleic Acid in Milk: Natural Sources, Nutritional Advantages, and Potential Health Benefits
Abstract: Cis-9, trans-11 conjugated linoleic acid (CLA) is the most common type of CLA found in milk. It has gained a lot of attention because it may have several health benefits. This bioactive lipid is primarily derived from ruminal biohydrogenation of dietary linoleic acid and endogenous synthesis in the mammary gland via Δ9-desaturase activity. Various dietary and management strategies influence CLA concentrations in milk, including forage composition, lipid supplementation, and grazing …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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Exploring Psychotropic Trends of Medication Use in Psychiatric Outpatients: An Observational Study at a Tertiary Care Hospital
Abstract: Background: Psychotropic medications are essential in managing a wide range of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia. Prescribing habits in outpatient clinics can differ a lot depending on things like the patient’s age, background, and medical conditions. Aim: This study aims to explore the trends in psychotropic medication use among psychiatric outpatients at a tertiary care hospital, with a focus on understanding prescribing patterns, demographic factors, and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 15–23 Read article
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Solar-Powered Electric Vehicle Charging Station Enhanced by IoT Integration
Abstract: This project introduces a solar-powered electric vehicle (EV) charging station that incorporates Internet of Things (IoT) technology to enhance monitoring and operational contr While the integration of solar energy for renewable power generation is promising, the real-time solar voltage monitoring system raises questions about the overall efficiency and dependability of solar energy under variable environmental conditions. The automatic detection of a vehicle’s position over the wireless charging coil, eliminating manual …
Published in Journal of Power Electronics and Power Systems · Vol. 15, Issue 2, 2025 · pp. 23–32 Read article
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Mechanisms of Crystal Growth: From Spiral Steps to Surface Adhesion
Abstract: Crystal growth is a complex interplay between thermodynamic stability and kinetic processes, influenced heavily by the conditions under which crystallization occurs—particularly the degree of supersaturation. This abstract outline three principal regimes of solution-grown crystal growth: defect-driven, two-dimensional, and adhesive growth. At low supersaturation, growth is facilitated at surface defects, such as screw dislocations, where energy barriers to attachment are minimized. This results in the formation of spiraling steps that propagate …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 46–31 Read article
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Fault Detection in Solar PV Systems Integrated with the Power Grid: Evaluating Logistic Regression through Confusion Matrix Analysis
Abstract: This paper proposes a method for failure detection in grid-integrated solar photovoltaic (PV) systems using logistic regression and real-time sensor data. The approach effectively classifies and identifies seven distinct fault types. The developed model demonstrates a high fault identification accuracy, ranging from 93% to 96.5% across various fault types and operational conditions. By leveraging logistic regression, the system utilizes key independent variables that significantly influence the classification process. Additionally, the …
Published in Journal of Power Electronics and Power Systems · Vol. 15, Issue 2, 2025 · pp. 45–52 Read article
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The Impact of High-Performance Computing on FEA and CFD Simulations
Abstract: The integration of advanced simulation techniques, such as Finite Element Analysis (FEA) and Computational Fluid Dynamics (CFD), has transformed mechanical design by enabling engineers to develop optimized, efficient, and reliable systems. FEA is widely applied to analyze structural mechanics, thermal stresses, and vibrations, offering detailed insights into material behavior and design performance. On the other hand, CFD focuses on simulating fluid flow, heat transfer, and aerodynamic performance, making it indispensable …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 26–35 Read article
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The Rising Burden of Heart Attacks: Causes, Trends, and Prevention Strategies
Abstract: Heart attacks, or myocardial infarctions, remain a leading cause of morbidity and mortality worldwide, with their incidence rising steadily across diverse populations. This review explores the increasing prevalence of heart attacks, emphasizing traditional risk factors, such as poor diet, physical inactivity, smoking, and medical conditions like hypertension, diabetes, and hyperlipidemia. It also highlights emerging risk factors, such as chronic infections, pollutants, substance abuse, and the lasting cardiovascular effects of COVID-19. …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 1–11 Read article
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The Transformation of Surgery: From Ancient Techniques to Modern Advancements
Abstract: Surgery has long been a cornerstone of medical practice, evolving from ancient rudimentary techniques to advanced, life-saving procedures. This article explores the critical role surgery plays in modern medicine, examining its significance in diagnosis, treatment, and patient care. It delves into how surgical interventions have become essential in managing a wide array of conditions, from acute trauma to chronic diseases, and highlights the advancements in surgical technology and techniques, such …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 19–41 Read article
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Algorithm for the prediction of cardiovascular disease (CVD)
Abstract: cardiovascular diseases (CVD) still claim a significant number of deaths globally and remain the number one killer with an annual death toll of nearly 17.9 million. While several medical advancements have been made, an early diagnosis is still hard to obtain, which often leads to worsening conditions and intricate treatment options. With the advancement of modern technology, Machine learning has demonstrated to be a miraculous tool which can greatly impact …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 Read article
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Developing Techniques for Controlling Different Aspects of Text Generation Such as Tone and Contents
Abstract: Large Language Models (LLMs) have shown excellent text creation quality in Natural Language Processing (NLP). However, LLMs have to satisfy ever-more-complex standards in real-world applications. LLMs are supposed to meet specific user goals, like as mimicking specific writing styles or producing material with poetic richness, in addition to eliminating inaccurate or objectionable content. Controllable Text Generation (CTG) techniques were developed in response to these diverse demands. They guarantee that outputs …
Published in Recent Trends in Programming languages · Vol. 12, Issue 2, 2025 · pp. 34–39 Read article
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Advances in Polymer-Based Nanocomposites for Moisture-Sensitive Applications
Abstract: Polymer-based nanocomposites have emerged as promising materials in sensor technology due to their superior mechanical, electrical, and environmental stability. These advanced materials offer unique advantages, such as enhanced sensitivity, durability, and adaptability to various environmental conditions, making them highly suitable for sensor applications. One of the most significant breakthroughs in this field is the integration of semiconducting nanoparticles (NPs) within a polymer matrix, which has led to remarkable improvements in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 145–152 Read article
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Controlled Release of Anti-Inflammatory Drugs from Biopolymer Matrices
Abstract: Carefully releasing anti-inflammatory drugs from natural materials is a new way to make treatments work better and cut down on the side effects of current drug delivery methods. To slowly release drugs, this method uses safe, reusable materials. It's a good alternative to pills or shots. Anti-inflammatory drugs that are used to treat long-term conditions like gout and inflammatory bowel disease work better when they are made in a controlled …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 388–399 Read article