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1074 articles for “PHA”
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pH-Triggered In-Situ Nasal Gel Systems for Migraine Therapy: A Review
Abstract: Intranasal drug delivery has gained considerable attention as a non-invasive route for delivering drugs to both systemic circulation and the central nervous system, particularly for the treatment of migraine. Traditional nasal formulations such as sprays and drops often show poor therapeutic performance due to rapid mucociliary clearance and limited retention within the nasal cavity. To overcome these challenges, in-situ gel systems have been designed, which transform from a liquid to …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Machine Learning Based Optimization of Polymer Structure Property Relationships in Composite Material Systems
Abstract: In modern engineering applications, polymer-based composite materials have garnered a lot of attention because of their lightweight nature, high strength-to-weight ratio, and changing physical features. In order to maximize the relationships between polymer structure and properties in composite materials, this study suggests a strategy based on reinforcement learning (RL). The research utilized the Polymer Composite Properties Dataset, which contains 12,700 records associated with polymer matrices, reinforcement fillers, interfacial bonding characteristics, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 242–255 Read article
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Spatiotemporal Analysis of Mean-Field Coupled Lorenz Oscillators for Applications in Electronic Network Design and Chaotic Synchronization
Abstract: This study investigates the spatiotemporal behavior of a network of 100 coupled Lorenz oscillators interacting through mean-field coupling with coupling strength κ = 0.1 and explores its relevance to electronic system design and nonlinear network architectures. While each oscillator follows classical Lorenz dynamics, the coupling mechanism enables collective behavior that resembles synchronization phenomena observed in distributed electronic and communication systems. Numerical simulations reveal rich dynamical characteristics including partial synchronization, emergent …
Published in Journal of Electronic Design Technology · Vol. 17, Issue 2, 2026 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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A Study to Assess the Effectiveness of a Structured Teaching Plan on Knowledge Regarding Premenstrual Symptoms Among Early Adolescent Girls in Selected Schools of Agra
Abstract: Premenstrual symptoms are commonly experienced by many women and can have a considerable impact on their everyday functioning and overall well-being. These symptoms involve physical, emotional, and behavioral changes that occur during the luteal phase of the menstrual cycle, with different levels of severity. The present study was conducted to evaluate the effectiveness of a structured teaching plan on knowledge regarding premenstrual symptoms among early adolescent girls in selected schools …
Published in International Journal of Midwifery Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 45–65 Read article
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Personalized Medicine: the impact of ferrofluids, clinical procedures, strategies, applications,challenges, current trends, and reseach opportunities.
Abstract: Personalized medicine has shown progressive development and evolution in health care systems. It is considered as transformative emerging medicine encorporating advanced technologies including genomics, AI as thinking partner, and nanotechnology in a greater extent. The quest for painless injection, lesstoxicity, rapid cell separation, and gene sequencing make ferrofluid the focus of personalized medicine. Currently, magnetic nanoparicles and ferrofluides are becoming driving force of personalized medicine. However, contronlling and managing nanoscale …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 Read article
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Recent Advances in Hybrid Polymer–Cement Composites: Interfacial Engineering, Self-Curing Mechanisms, and Microstructural Performance
Abstract: The increasing demand for high-performance polymer-modified cementitious composites has stimulated extensive research into hybrid self-curing composite systems with engineered aggregate phases. Self-curing hybrid polymer–cement composite systems, using recycled aggregates, constitute one of the solutions proposed by researchers to overcome problems related to moisture loss during the curing process, shrinkage, cracking, and the limited amount of natural aggregate available. This critical review provides an overview of recent developments concerning the production, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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Hakim Ismail Jurjani (1042–1137 AD): Life, Works, and Medical Legacy
Abstract: Hakim Ismail Jurjani, also known as Seyyed Isma’il Jorjani, was among the most distinguished physicians and scholars of medieval Persian medicine whose contributions significantly influenced the development of Greco-Arab and Unani medical traditions. His monumental encyclopedia, Zakhīra Khwārazmshāhī (Treasure of the Khwarazm Shah), is regarded as one of the greatest medical compilations of the Islamic Golden Age and represents a landmark in the evolution of Persian scientific literature. Unlike earlier …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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The Burden of Empirical Therapy: Analyzing the Predominance of Broad-Spectrum Antibiotic Usage in Lower Respiratory Tract Infections
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Managing Chronic Diseases: Diabetes Mellitus
Abstract: Diabetes mellitus is one of the most prevalent chronic non-communicable diseases worldwide and represents a major public health challenge due to its long-term complications, increasing prevalence, and economic burden on individuals and healthcare systems. It is distinguished by chronic hyperglycemia brought on by deficiencies in either insulin action or secretion, or both. Diabetes causes increasing harm to several organ systems, including the kidneys, eyes, neurological system, and cardiovascular system, if …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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A Comprehensive Review on the Role of Antacids in the Management of Stomach Disorders
Abstract: Antacids are among the most widely used over-the-counter medications for the symptomatic management of acid-related gastrointestinal disorders, including dyspepsia, gastroesophageal reflux disease (GERD), gastritis, and peptic ulcer disease. These agents provide rapid relief by neutralizing gastric hydrochloric acid, thereby increasing intragastric pH and reducing mucosal irritation. In addition to their therapeutic benefits, the long-term and excessive use of antacids may be associated with adverse effects and toxicological concerns, including electrolyte …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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Design, Synthesis, and in vitro Evaluation of Novel Benz/Imidazole-2-acetonitrile Derivatives as Antibacterial and Antifungal Agents
Abstract: Benzimidazole is a pharmaceutically important compound. In this research, we were able to prepare several heterocyclic derivatives from it by first preparing a new azo derivative ZH through a reaction of 3-aminoacetophenone with benzimidazole-2-acetonitrile. This azo derivative was then introduced via a condensation reaction with aromatic amine derivatives, resulting in the preparation of two Schiff base derivatives Z1 and Z2. From these bases, six and seven membered heterocyclic derivatives were …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 53–87 Read article
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A Review of Modifications of Cement Slurry Formulations for Carbon Dioxide Storage
Abstract: Climate action, which includes activities aimed at mitigating climate change or reducing its adverse impacts, is the thirteenth goal of the 2030 SDGs (Sustainable Development Goals). Tthe successful commercial deployment of CCS technology would heavily rely on the integrity of the cement sheath used to complete the wellbores at the CO₂ storage sites. It has been established that the cement sheath made from conventional ordinary Portland cement (OPC) is not …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 2, 2026 · pp. 1–21 Read article
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Bridging Traditional Ayurvedic Pedagogy and Competency-Based Education: A Contemporary Perspective
Abstract: Mentoring plays a pivotal part in education. It has deep roots in both the traditional practitioner- Shishya Parampara of Ayurveda and ultramodern faculty- grounded medical education. The National Medical Commission and the National Commission for Indian System of Medicine have stated that structured mentorship programs are essential to guide scholars from newcomers to interpreters. This composition looks at how these traditions connect. It explains the purpose and limits of mentoring. …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 15, Issue 2, 2026 Read article
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Evaluation of Drug Utilization Patterns and Prescription Trends in Patients with Hypothyroidism and Hyperthyroidism in a Tertiary Care Hospital
Abstract: Background: Endocrine disorders affecting the thyroid gland represent some of the most frequently encountered conditions globally, necessitating prolonged therapeutic intervention and vigilant clinical surveillance. The evaluation of Drug utilization patterns (DUE) serves an essential function in examining prescriptive behaviours and promoting appropriate pharmaceutical management. Objective: To evaluate drug utilization patterns, prescribing trends, and rationality of therapy in patients with hypothyroidism and hyperthyroidism. Methods: A prospective, cross-sectional observational investigation was performed …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 2, 2026 · pp. 1–5 Read article
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An Analytical Study of the Effectiveness of the Child Development Scheme in Anganwadi Centers of Rudraprayag District
Abstract: From the perspective of human development, childhood is regarded as a highly sensitive and multidimensional phase that plays a pivotal role in shaping the trajectory of human life. During childhood, children undergo rapid growth across their mental, social, psychological, and physical domains. Currently, the mental, physical, and social well-being—as well as the overall health—of children remains a grave challenge for the entire world. An increase in nutritional and health-related problems …
Published in International Journal of Children · Vol. 3, Issue 2, 2026 · pp. 35–47 Read article
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Strategies for the Development and Optimization of Orally Disintegrating Tablets (ODTs) to Improve Bioavailability and Patient Compliance
Abstract: Background: Pharmaceutical scientists have developed Orally Disintegrating Tablets (ODTs) to advance patient drug acceptance and biological system availability through simplified medi-cation delivery especially for children and senior citizens and people who cannot swallow pills regularly. The oral disintegrating tablets dissolve in the mouth within thirty seconds or less (USP 701) while needing no additional liquid thus making them suitable for both emergency treatments. Objective: The research examines ODT development strategies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Novel 1,3,4-Thiadiazole Derivatives: Design, Synthesis, Characterization and Anticancer Evaluation – A Review
Abstract: Cancer remains one of the leading causes of mortality worldwide despite significant advances in diagnosis and treatment. The clinical usefulness of many anticancer drugs is often restricted by toxicity, poor selectivity, and the emergence of drug resistance. These limitations have encouraged the search for novel heterocyclic compounds with improved therapeutic efficacy and safety. Among these, the 1,3,4-thiadiazole scaffold has gained considerable attention because of its favorable physicochemical characteristics, metabolic stability, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Enhancing the Bioavailability of Polyphenols: A Comprehensive Review
Abstract: The polyphenolic compounds are abundantly found in different plant parts including fruits, leaves, stem and seeds, and are known for possessing a wide range of biological activities. These include antioxidant, antimicrobial, anti-inflammatory, anticancer, antidiabetic, cardioprotective, and neuroprotective effects. Their functional relation with their structure highlights the significant therapeutic potential. As a result, the polyphenols are being further being exploited for applications in functional foods, pharmaceuticals, and targeted drug delivery. Despite …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 2, 2026 · pp. 37–51 Read article
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Synthesis and Structural Characterization of Nanocrystalline CeO2 and Ce0.95Cu0.05O2 Solid Solution Catalysts Properties and its Applications
Abstract: The Main study and the development of CeO2 and Cu doped CeO2 nanocrystals containing transition-metal species are of crucial importance for understanding the preparation and fabrication of CeO2 and Cu doped CeO2 nanoparticles by solution combustion technique to taken glycine as fuel. Here, we have investigated the effect of Cerium dioxide and Cu dopant ions on the structural properties of Ce1-xCuxO2 nanocrystals (NCs) synthesized via co-precipitation technique. XRD results confirmed …
Published in Journal of Catalyst & Catalysis Read article