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1222 articles for “design and development”
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Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 38–54 Read article
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Music Reactive led using Arduino
Abstract: In recent years, the integration of technology into interactive systems has garnered significant attention. Among the many applications, music-reactive LED systems have become popular, offering dynamic visualizations that respond to audio inputs. This paper explores the development and implementation of a music-reactive LED system using Arduino, focusing on real-time audio signal processing and LED control based on the frequency spectrum of the sound. By utilizing Fast Fourier Transform (FFT) algorithms …
Published in Journal of Microelectronics and Solid State Devices · Vol. 13, Issue 1, 2026 · pp. 27–33 Read article
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A Systematic Review on Factors Contributing to Infertility
Abstract: Infertility is a multifactorial reproductive health condition affecting approximately 10–15% of couples worldwide and continues to represent a major clinical and social challenge. Despite substantial advances in assisted reproductive technologies, diagnostic methods, and therapeutic interventions, many couples still face difficulties in achieving pregnancy. The impact of infertility extends beyond physical health, often leading to emotional distress, social pressure, and financial burdens, especially in societies where parenthood is highly valued. Consequently, …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 1, 2026 · pp. 31–35 Read article
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Remote Controlled Boat for Water Pollution Monitoring
Abstract: The global issue of water quality degradation caused by pollution has become a critical environmental concern. Leaving water unchecked for an extended period make it unfit for human needs and eradicate the entire water ecosystem. Water being considered as a vital element in sustaining living things need to be protected. To address this challenge, novel technological solutions are being devised to effectively monitor and manage water resources. This study introduces …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 1, 2024 · pp. 34–43 Read article
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Prevalence and Distribution of Staphylococcus Aureus in Clinical Samples Across Age Groups
Abstract: The bacteria that cause everything from ordinary skin infections to serious illnesses is called Staphylococcus aureus. It is now known that Staphylococcus aureus may develop resistance to a variety of drugs. Staphylococcus aureus has been displaying an unusual kind of resistance to antibiotics, especially to those based on β-lactum. As a result, Methicillin Resistant Staphylococcus Aureus (MRSA) is the new name for the resistant strain of Staphylococcus aureus. The prevalence …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 15–19 Read article
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Charging System for Electric Vehicle and Hybrid Electric Vehicle in Running Condition: A Review
Abstract: This study examines comparative studies of three different charging systems used in electric vehicles while they are moving or operating. It also deals with the idea of using an alternator at each wheel of the vehicle to charge the non-connected set of batteries, as well as a brief explanation of the principles, mechanisms, design, and constraints of fuel cells, solar panels, and regenerative brakes. These are some of the most …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 2, 2024 · pp. 10–18 Read article
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A Study on Leveraging Sensors and AI in Insect-Inspired Robotics for Unstructured Environments: Bio-Inspired Autonomy
Abstract: Insects, with their unparalleled agility, resilience, and highly efficient sensory-motor control in complex, unstructured environments, offer a rich blueprint for the next generation of autonomous robots. This study explores the design, implementation, and potential of insect-inspired robots, focusing on the synergistic integration of miniaturized sensor arrays and advanced Artificial Intelligence (AI) algorithms. We delve into bio-mimetic sensing, drawing inspiration from compound eyes, olfactory systems, and tactile hairs, to equip robots …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 3, Issue 2, 2025 · pp. 7–21 Read article
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Seismic Response Characterization of Vertically Irregular Multi-Storey Buildings Incorporating Mass and Stiffness Variations Using E-TABS Software
Abstract: The increasing demand for innovative architectural designs has led to the widespread use of vertically irregular configurations in high-rise reinforced concrete (RC) buildings. However, such irregularities significantly influence structural performance under seismic loading conditions, leading to complex structural behaviour and stress concentration at specific levels This study focuses on evaluating the seismic behaviour of vertically irregular multi-storey buildings using nonlinear time history analysis, which provides a realistic representation of structural …
Published in Recent Trends in Civil Engineering & Technology · Vol. 16, Issue 3, 2026 Read article
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Revealing the Hemodynamic Orchestra: Contrasting Analysis of Blood Flow Patterns in a Bifurcated Carotid Artery
Abstract: Understanding blood flow patterns in the carotid artery (CA) is crucial for detecting cardiovascular diseases. Computational fluid dynamics simulations compared non-Newtonian (non-Newt) and Newtonian (Newt) models under pulsatile and laminar flow. CA geometry was accurately designed using ANSYS Space Claim & Fusion360, and simulations were run in ANSYS Fluent. Discrepancies between non-Newt and Newt models were found, especially in bifurcation's distal regions prone to plaque. Pressure ranged from 27.870 Pa …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 229–247 Read article
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Enhanced Sensitivity Iontronic Pressure Sensor Gauge Using Laser-Created Micro-Pyramid Structures for Wide Linear Range
Abstract: The achievement of high sensitivity, ultrahigh pressure resolution, and great linearity across a wide pressure range under huge pressure preloads remains a challenge despite the substantial development of flexible capacitive pressure sensors. Here we offer an ultrathin ionic layer-integrated microstructure creation process that is configurable. At 1700 kPa, the sensor's linear range sensitivity is 33.7 kPa-1; at 2000 kPa, the pressure resolution is 0.00725%, and the detection limit is 0.36 …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 107–118 Read article
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Braegen Monitor: Virtual Diagnosis And Home Training For Children With Cognitive Disabilities
Abstract: Braegen Monitor is an innovative software solution designed to support children with cognitive disabilities by providing personalized home-training and engagement activities. The platform enables caretakers to submit EEG reports through the app, which are then virtually analyzed by a child psychiatrist. This ensures timely and professional diagnosis without the stress of frequent hospital visits. A unique feature of Braegen Monitor is the psychiatrist’s personal interview with the caretaker or parent …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 44–54 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article
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LLM Evolution: Secrets and Disadvantages
Abstract: The advancement of large language models (LLMs) has initiated a significant transformation in artificial intelligence, with substantial effects on fields including natural language processing, machine learning, and human-computer interaction. This research examines the diverse improvements in LLMs, emphasizing significant milestones from early models such as GPT-2 to contemporary state-of-the-art designs. The investigation highlights the novel training methodologies, such as unsupervised learning and transfer learning, which have markedly improved the capabilities …
Published in Journal of Web Engineering & Technology · Vol. 12, Issue 1, 2025 · pp. 25–36 Read article
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Building Scalable Microservices with Micronaut, Kotlin, and AWS DynamoDB: A Comprehensive Architecture Study
Abstract: The evolution of enterprise software has trended steadily toward microservice architectures due to their inherent scalability and resilience advantages over monolithic systems. This research explores a comprehensive implementation approach using Micronaut, an innovative JVM-based framework specifically designed for resource-efficient microservices. The study combines Micronaut with Kotlin programming language and leverages AWS DynamoDB as a scalable NoSQL persistence layer, with Apache Kafka providing event-driven communication capabilities. We explore the critical role …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 2, 2025 · pp. 40–57 Read article
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AI and Sensor Systems Revolutionizing Intoxication and Smoking Pre- Detection
Abstract: In an increasingly interconnected and safety-conscious world, the pervasive issues of intoxication and uncontrolled smoking continue to pose significant threats to public health, safety, and productivity. From impaired driving incidents to workplace accidents, and from chronic health conditions linked to smoking to the risk of fires, the societal and economic costs are staggering. However, a new frontier in preventative technology is emerging: sophisticated AI and sensor-based systems designed for the …
Published in Journal of Control & Instrumentation · Vol. 16, Issue 3, 2025 · pp. 14–25 Read article
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Advancement in Biodegradable Equipment for Flexible and Sustainable Electronics
Abstract: Biodegradable electronics are a quickly developing area focused on reducing the environmental impact of traditional electronic waste by using materials that can break down naturally after use. These devices use eco-friendly polymers, nanocomposites, and bio-based materials that maintain electrical function temporarily before safely decomposing. Recent developments show the potential of plant-based polymers, conductive biodegradable composites, and transient materials that support flexible and wearable applications without causing long-term harm to the …
Published in International Journal of Electro-Mechanics and Material Behaviour · Vol. 3, Issue 2, 2025 · pp. 32–37 Read article
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Spintronic Logic Circuits for Ultrafast Processing
Abstract: Spintronic logic has emerged as one of the most promising post-CMOS paradigms capable of addressing the speed, density, and energy challenges of deeply scaled silicon technologies. By relying on the intrinsic properties of electron spin and magnetization dynamics, spintronic devices—particularly Magnetic Tunnel Junctions (MTJs), Spin-Transfer Torque (STT), and Spin–Orbit Torque (SOT) structures—enable ultrafast, non-volatile data processing with significantly reduced energy consumption. Despite remarkable device-level advancements, circuit- level realization of high-speed, …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 2, 2025 · pp. 35–43 Read article
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Nanotechnology meet phytomedicine towards smarter drug delivery system.
Abstract: Using bioactive substances derived from plants, or phytomedicine, has long shown promise in treating a variety of illnesses with fewer adverse effects than synthetic medications. Nevertheless, a lot of phytochemicals have issues with inadequate targeting in vivo, low bioavailability, poor solubility, and chemical instability. By enabling encapsulation, controlled release, targeted delivery, and stimuli responsive behavior, nanotechnology provides effective tools to get around these restrictions. This review examines the intersection of …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 46–53 Read article
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Integration of IoT and Robotics for Smart Industrial Waste Management: Design and Implementation of an Automated Collection System
Abstract: All types of drainage issues are resolved by the Automatic Industrial Hazardous and Waste Collecting Machine. Washing, which also encourages blockage-free drains and a constant flow of drain water. Sewage water needs to be separated in the present period due to sufficient sewage to maintain environmental cleanliness. Both humans and the environment are severely harmed by the garbage and pollutants generated by industry and the areas around cities. Using auto …
Published in International Journal of Advanced Control and System Engineering · Vol. 1, Issue 1, 2023 · pp. 26–34 Read article
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Characterization of Strength of Aluminum (Al 6063-T6) After Corrosion
Abstract: Aluminum are frequently used as light weight structure in various nautical design. One of them is the ship structure design where sever environment of saline water influences the damage of the structure and one among them is pitting. In this paper, an experimental verification of strength and impact of corrosion effect on Al-6063–T6 aluminum was presented. The specimens were exposed to saline water for various duration like 500 hrs, 750 …
Published in Journal of Experimental & Applied Mechanics Read article