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132 articles for “toxicity test.”
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Antibacterial Property of Crocus Sativus L.
Abstract: ABSTRACTCrocus sativus commonly called saffron has been used widely in Middle East and South East Asia as a drug to promote health and to fight diseases. Saffron though cultivated in different parts of the world, is mainly cultivated in Iran. It has wide range of medical uses such as antitumor, antifungal and antiinflammatory activities. Characteristic components of saffron are crocetin, picrocrocin and safranal that are responsible for color, bitter taste, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 1, Issue 1, 2012 · pp. 17–23 Read article
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Bio-physiochemical analysis of Algae –Gasoline and Butanol-Gasoline blended fuels
Abstract: AbstractThe main objective of this paper was to formulate and identify the physiochemical characteristics of fuel blended with algae oil, butanol and gasoline. The comparison of the characteristics of algae and butanol blended with gasoline is also presented in the paper. These blends have been prepared with three different blending ratio 5%, 10% and 15%, respectively. The requirement of another source of energy is increasing rapidly as fossil fuels are …
Published in Journal of Energy, Environment & Carbon Credits · Vol. 8, Issue 1, 2018 · pp. 10–16 Read article
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Physicochemical and Fatty Acid Profiling of Rice Bran Oil and Its Quality Characteristics
Abstract: The continued demand for edible oils by the ever-increasing population makes it pertinent to explore new sources. In this direction, rice bran oil has been subjected to toxicological and nutritional evaluations of their chemical’s constituents. The objective of the study was to determine the physicochemical analysis and fatty acid composition. Physicochemical properties like acid value, color, specific gravity, refractive index, saponification value, iodine value, peroxide value, unsaponifiable matter, and test …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 3, 2019 · pp. 6–10 Read article
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Toxicity of Copper Sulphate on Behaviour, Hematological and Biochemical Parameters of Mrigal Cirrhinus mrigala
Abstract: The present study deals with the toxicity of copper sulphate on behavior, hematological and biochemical parameters of Mrigal Cirrhinus mrigala. Copper sulphate was prepared and characterized by using SEM, FTIR and XRD. The physic-chemical characteristics of water sample were analyzed before the experiment. The sub-lethal analysis on Cirrhinus mrigala in different concentrations such as 10–40 and 50 ppm of copper sulphate were used for a period of 96 h. Based …
Published in Research and Reviews: A Journal of Toxicology · Vol. 11, Issue 1, 2024 · pp. 26–32 Read article
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In vitro and in vivo Anti-Oxidant and Anti-Diabetic Evaluation of cladodes Crude Extract and Solvent fractions of Opuntia elatior mill (Cactaceae)
Abstract: Objective: Ariel part of Opuntia elatior (Cactaceae) has been used in folklare remedies to treat diabetes in America, Mexico and India. However, the anti-diabetic potential of cladodes of this medicinal plant is not scientifically validated and authenticated. The present study aimed to evaluate in vitro and in vivo anti-oxidant and anti-diabetic potential of methanol extracts and solvent fractions of O. elatior cladodes. Methods: Phytochemical analysis performed according to standard procedure. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 2, 2025 · pp. 77–88 Read article
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Impact of Grape Seed Extract on Liver Function against Cadmium Chloride-Induced Toxicity
Abstract: The present study was designed to evaluate the antioxidant activities of grape seed and to benefit from the impact of grape seed on hepatotoxicity mediated by cadmium chloride (CdCl2). Gas liquid chromatography (GC-MS) was used to assay the chemical profile. A total of 40 male rats (10 rats per group) were divided into four groups: (1) control group, (2) grape seed group: rats treated with grape seed extract (GSE) at …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 3, 2020 · pp. 30–39 Read article
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TOXICOLOGY: Present-Day Difficulties for Investigating Safety Science and Target Safety Evaluation of Major Human Hepatocytes
Abstract: Preclinical toxicology has developed into a more thorough understanding of toxicity pathways from its descriptive beginnings. Technological developments have made it possible to forecast safety occurrences, mitigate adverse effects, and create safety biomarkers. Because they are able to self-renew and specialize into different types of human body cells, stem cells are currently being employed for in vitro toxicological applications. However, as compared to primary human hepatocytes, stem cell-derived HLCs perform …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 3, 2024 · pp. 31–40 Read article
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Synthesis and Chemical Characterization of Novel Series of Benzoxazinone Derivatives
Abstract: The objective of the current work is to synthesize some novel benzoxazinone derivatives and to study their antibacterial activity in particular. Thus an effort has been made in this direction. The antimicrobial activity of the synthesized some novel benzoxazinone derivative is summarized.As estimated, benzoxazinone derivatives exhibited significant to moderate antimicrobial activity. Therefore, a detailed study of toxicity is necessary. Heterocycles formed the sites of reactions in many enzymes or co-enzymes. …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 41–57 Read article
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Analgesic Activity and Acute Toxicity Study of Zornia gibbosa Span (Samyojaki) in Mice
Abstract: The herb Zornia gibbosa Span is a member of fabaceae family and commonly known as Nellujollusoppu/Haradahacchaga in Udupi district of Karnataka. The drug is widely used in the treatment of fracture by folklore practitioners to pacify pain and inflammation. In fracture the pain is generated by multiple nociceptors presence in response to discontinuity of periosteum and endosteum during trauma. So in order to justify the folklore claims, pharmacological analysis of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 1, 2014 · pp. 1–4 Read article
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Origin and Development of Forensic Science and Branches of Forensic Science
Abstract: Forensic science is like the Sherlock Holmes of the real world, blending scientific expertise, legal acumen, and investigative prowess to crack cases and bring justice to the forefront. It’s essentially the art of using scientific methods to untangle the mysteries of crimes and legal disputes. Picture this: a team of experts delving into the minutiae of evidence – from DNA samples to fingerprints, from chemical analyses to digital footprints – …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article
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Computational Biomodeling: Transforming Drug Design with Advanced Simulations
Abstract: Computational biomodeling has emerged as a transformative approach in the field of drug discovery, significantly enhancing the efficiency and precision of identifying and optimizing potential drug candidates. This article explores the various computational techniques utilized in drug design, including molecular docking, molecular dynamics (MD) simulations, free energy calculations, and virtual screening, and examines how these methods collectively contribute to the drug development process. The integration of these advanced simulations allows …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 24–29 Read article
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Green Fabrication of Glutaraldehyde-Crosslinked Chitosan/PVA Biocomposite for Heavy Metal Removal from Wastewater
Abstract: Chitosan (CS) and Polyvinyl alcohol (PVA) are polymers that possess biodegradable, biocompatible, and non-toxic properties, making them suitable for wastewater treatment applications. The primary objective of this research is to chemically modify chitosan in a novel manner to enhance its ability to remove hexavalent chromium Cr(VI) from aqueous solutions. In this study, a composite material was synthesized by crosslinking PVA and CS with glutaraldehyde (GA), resulting in the formation of …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 59–83 Read article
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Develop And Assess a Multifunctional Herbal Face Pack
Abstract: This study aims to develop and assess a multifunctional herbal face pack that reduces tan lines and brightens skin through the trituration of herbal ingredients. Following preparation, the formulation is assessed using a variety of criteria, including, extrudability, stability, irritant test, physicochemical, and organoleptic factors. Physically, the formulation was found to be good, devoid of skin irritation, and able to retain its consistency even after stability in storage. An herbal …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 1–7 Read article
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Development of Eco-friendly Glass Fiber Composites Embedded with Paddy Stubble for Sustainable Applications and Its Metallurgical Characterization
Abstract: The extreme rise in environmental challenges owing to agricultural activities, among which paddy stubble burning remains a huge concern. Burning about 15 million tons of paddy stubble leads to emissions discharge of various toxic pollutants and gases notably, nitrogen oxides, methane and carbon monoxide in large scale causing global air pollution and climate change. The study focuses on obtaining and preparing a paddy stubble powder and using it with glass …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 640–648 Read article
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Antidiabetic and Antioxidant Activity of Leaves of Aegiceras corniculatum (L.) Blanco (Black Mangrove): An in vitro and in vivo Study
Abstract: AbstractPurpose: Aegiceras corniculatum (L.) Blanco, commonly known as Black Mangrove, is a species of shrub or tree mangrove with a distributed Indian mangrove forest and traditionally used to treat diabetes and other health ailments. Aim: The objective of this work was to enlighten the function of Indian mangrove variety of A. corniculatum leaves on carbohydrates blemishing reactions through diabetes using in vitro and in vivo methods. Methods: The aqueous leaves …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 1, 2018 · pp. 23–31 Read article
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Effects of the Embryonic Bisphenol an Exposure on The Postnatal Development, Learning and Memory of Rat Offspring: Fundamental Study
Abstract: We studied the morphologic changes in some organs and changes of learning and memory of the rat offspring after the embryonic bisphenol A exposure. Background: Bisphenol A, widely used as polycarbonate plastics material to manufacture food packaging, toys, glasses, computers, kitchen utensils and medical instruments, is one of the most common endocrine-disrupting chemicals. It is demonstrated that bisphenol A may be mingled with foodstuff and beverage from package and receptacle. …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 58–63 Read article
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Investigating Curcumin Phytocompounds as Prospective Parkinson's Disease Therapeutic Agents: A Computational Method that Targets LRRK2 Protein
Abstract: Objective: Parkinson’s Disease is the second stage predominant neurodegenerative illness. Primary aetiology is still unknown. One of the biggest battlegrounds in modern medicine is discovering the cause of Parkinson’s disease (PD), as well as the hunt for palliative treatments and, if feasible, a cure. The objective of this work is to identify the phytocompounds from curcumin (curcuma longa) for the treatment of PD. Curcumin, a well-researched phytochemical, has been suggested …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 55–67 Read article
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Biological Synthesis of Silver Nanoparticles Using Hibiscus Sabdariffa Leaf Extract and It’s Antibacterial Sensitivity Assay
Abstract: In this study, AgNO3 was effectively used to synthesize silver nanoparticles. Hibiscus sabdariffa leaf extract was used to promptly and easily synthesize silver nanoparticles. An UV-Visible spectrophotometer showed absorbance peak in range of 300-600 nm. The procedure was found to be easy to follow, quick, least step and safe for the environment. It is non-toxic, and a viable substitute for traditional physical or chemical procedures. At room temperature, silver ions …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 08–13 Read article
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Adjuvant Unani Formulations used in Fournier’s Gangrene Patient: A Case Study
Abstract: Fournier’s gangrene is a rare infection characterized with fast-progressing myonecrosis, which affect regions of perineum, genitalia and perianal area. E. coli, Pseudomonas aeruginosa, Streptococcus putridus, Staphylococcus and Klebsiella are commonly involved. Symptomatically presented as sudden pain in the scrotum, fever, severe toxicity, very fast spreading cellulitis of scrotal skin, extending to the groin and often to anterior abdominal wall. The aim of this case study is to acknowledge the effectiveness …
Published in Research and Reviews : Journal of Surgery · Vol. 10, Issue 2, 2021 · pp. 35–41 Read article
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Suitability Analysis of Different Batteries with Off-Grid Photovoltaic System
Abstract: The main objective of power generation and distribution companies is to ensure uninterrupted supply at reasonably low cost, minimum losses and high quality. Considering rural areas, where off-grid power systems using renewable resources are becoming more popular are generally equipped with storage elements like batteries. Hence energy storage and battery management system are a vital area of research nowadays. The study presents modelling of an off-grid solar PV model and …
Published in Research & Reviews : Journal of Physics · Vol. 7, Issue 3, 2018 · pp. 11–19 Read article