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1325 articles for “limitations”
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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Estimation of Alogliptin and Dapagliflozin in Synthetic Mixture by RP-HPLC Method
Abstract: The primary objective of the proposed research was to develop and validate analytical methods for the simultaneous quantification of Alogliptin and Dapagliflozin in a synthetic mixture. Alogliptin and Dapagliflozin are medications used for managing diabetes, with Alogliptin inhibiting the enzyme Dipeptidyl peptidase-4 and Dapagliflozin belonging to the class of sodium-glucose cotransporter 2 inhibitors. High-performance liquid chromatography method development was conducted using a C18 column (250 mmX4.6 mm, 5 μm particle …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 37–46 Read article
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UV Method of Development and Validation of Olaparib
Abstract: An analytical method must be developed and validated in the discovery, development, and production of pharmaceuticals to ensure the identification, purity, potency, and performance of drug commodities. Quality control laboratories use official test protocols that emerge from the processes. A simple ultraviolet spectrophotometric approach was designed and validated using various characteristics, including linearity. Precision, reproducibility, accuracy, robustness, ruggedness, limit of detection, and limit of quantification are among the measuring criteria. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 20–27 Read article
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Reaching Conditions for Discrete-time Sliding Mode Control: Analysis and Design
Abstract: Sliding mode control (SMC) is a robust control method widely used in engineering due to its ability to handle uncertainties and disturbances effectively. In discrete-time sliding mode control (DSMC), system trajectories are constrained to sliding surfaces in the state space, leading to improved performance and stability. This paper provides an overview of DSMC, focusing on its applications, advantages, and limitations. It discusses the use of DSMC in various engineering fields …
Published in International Journal of Electrical Machine Analysis and Design · Vol. 2, Issue 1, 2024 · pp. 7–14 Read article
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An Examination of Energy-Saving Techniques for UAV Communication
Abstract: Unmanned aerial vehicles (UAVs), or drones, have become essential in various industries due to their low deployment costs and exceptional versatility. As a result, they are widely used in industries like mining, agriculture, logistics, and search and rescue. The effectiveness of UAV applications is largely dependent on robust communication technology, which is crucial for control, data transmission, and coordination. However, the limited capacity of the low-power batteries used in UAVs …
Published in International Journal on Drones · Vol. 1, Issue 1, 2025 · pp. 1–7 Read article
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Leveraging Full Stack Data Science for Healthcare Transformation: An Exploration of the Microsoft Intelligent Data Platform
Abstract: The rapid progress of the Fourth Industrial Revolution has been largely driven by the evolution of artificial intelligence (AI), with notable contributions from technologies such as Generative Pre-trained Transformers (GPT). This revolution has seen the convergence of physical, digital, and biological technologies, leading to transformative impacts across various sectors. Data science, serving as a crucial enabler, has enabled the development of intelligent value chains. However, the application of data science …
Published in Journal of Advanced Database Management & Systems · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
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Fiber Reinforced Concrete (FRC) as Composite Material in Pavement
Abstract: Conventional bituminous pavements are extensively utilized across India, yet they face challenges such as limited impact resistance, low tensile strength, and brittleness compared to concrete alternatives. Despite concrete's superior strength and durability, it exhibits deficiencies in ductility, fatigue resistance, and ability to withstand substantial deformations. This research delves into the feasibility of fiber-reinforced concrete as a composite material for pavements, with a primary goal of extending the service life of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 137–143 Read article
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Augmented Reality Based 3D Drawing from the 2D
Abstract: Students benefit from this approach since it offers an alternative viewpoint on content production and teaching and learning techniques. Managing global projects necessitates the use of techniques and resources to aid in content communication. The development of augmented reality (AR)/virtual reality (VR) content requires a significant amount of time if efficient design and visualization techniques are not employed. The use of highly detailed 3D games that may have required a …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 3, 2024 · pp. 10–17 Read article
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Novel Catalytic Strategies for Reducing Residual Stresses and Improving Surface Quality in Machined Ceramic Materials
Abstract: To prepare for material cutting and utilize utility-specific edges, it’s crucial to understand the inherent brittleness of ceramics. This brittleness limits the forming methods available and hinders achieving dimensional accuracy and precision through conventional machining techniques. The fabrication of composite materials is becoming increasingly significant, particularly in technical fields like the automotive industry, where they are used to manufacture engine connecting rods, propeller shafts, brake discs, and more. The machining …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 2, 2024 · pp. 01–07 Read article
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Heavy Metal Contamination of Groundwater in Malwa Region of Punjab and Potential Technological Solutions
Abstract: Bathinda is part of the Malwa region of Punjab and is part of a belt which was earlier called the cotton belt of India but is now hailed as the cancer belt of India. The Malwa region faces high cancer incidence rates. For every 1 million people living in this region, 1089 are diagnosed with cancer. The rate of cancer in the Malwa region is 36.13% higher than the national …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 3, 2024 · pp. 1–14 Read article
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RP-HPLC method for simultaneous determination of Drospirenone and Ethinylestradiol in Bulk and their Pharmaceutical dosage form
Abstract: Oral contraceptive is used to prevent the pregnancy which is contain hormones to block the release of eggs from the ovaries. Most of them contain estrogen and progesterone. Nowadays, usage of hormonal contraceptive is sharply enhancing; around 100 million of women worldwide are taking these drugs. With this drug fertility rate can be supressed as long as they want or plan their activity along with these drugs provide efficacy, reliability, …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 46–67 Read article
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Challenges and Opportunities in the African Pharmaceutical Industry
Abstract: Background: The pharmaceutical industry in Africa has significant potential for growth; however, it is overwhelmed with grappling challenges. Nonetheless, these challenges can create a window of opportunities for innovation. This article provides an in-depth analysis of the profound challenges and opportunities in the continents pharmaceutical industry. Methods: Using data collected from published literature, reports and gray literature was used to conduct a narrative review. Using data collected from various publications …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 88–98 Read article
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A Review on Heavy Metal Removal Techniques in Water Treatment
Abstract: The removal of heavy metal ions from wastewater is crucial for environmental safety and human health due to the toxic and persistent nature of these pollutants. This review comprehensively examines various water treatment methods, including adsorption, membrane filtration, chemical precipitation, electrochemical, and photocatalytic processes. Each technique is critically analyzed in terms of removal efficiency, operating conditions, and their respective advantages and limitations. Adsorption methods, particularly those using bioadsorbents, have gained …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 3, 2024 · pp. 15–28 Read article
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Cyberattack Detection and Prevention Using Empowering AI Tools
Abstract: With more organizations entering the digital transformation sphere, the opportunities and risks in cyberspace have increased and gone up in levels of sophistication and occurrence. Many of these developments are attributed to the limits of existing cyber security solutions where addressing new threats requires advanced detection technologies and techniques. Cyber threats gained a new meaning and dimension with artificial intelligence (AI) coming into play in ways that supplement security systems …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 2, 2024 · pp. 1–7 Read article
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Design And Optimization Of High-Speed Array Multiplier
Abstract: An array multiplier is a digital circuit used for the rapid multiplication of binary numbers. It employs an array of logic gates to generate partial products concurrently, significantly enhancing speed. The array structure divides the multiplication task into smaller, parallel processes, allowing for efficient parallel processing of multiple bits. Each cell within the array manages specific bit-level multiplications, and their results are summed to produce the final product. This parallel …
Published in Journal of Microelectronics and Solid State Devices · Vol. 11, Issue 3, 2024 Read article
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Emerging Trends in Drones across Multiple Sectors
Abstract: Drones, also known as unmanned aerial vehicles (UAVs), have become increasingly popular for their adaptability, affordability, and advanced functionalities. Originally developed for military purposes, they are now widely utilized across diverse sectors such as agriculture, filmmaking, and search and rescue missions. The impact of drones has been significant in various domains, such as reducing human casualties, providing more accurate information, increasing efficiency and cost reduction, and improving crop yields. Nonetheless, …
Published in International Journal of Mechanical Dynamics and Systems Analysis · Vol. 2, Issue 2, 2024 · pp. 29–35 Read article
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Educating Compilers to Learn: Utilizing Machine Learning for More Brilliant Code Optimization
Abstract: This study explores the use of machine learning (ML) approaches to compiler optimization. The now-traditional static compilation techniques are transformed into adaptive, dynamic systems capable of making context-specific advancements. Traditional compilers rely mostly on heuristic or rule-based optimization techniques. While these techniques work well in general cases, they consistently fail to adapt well within the limits of code structures that modern machines display. This limitation is especially acute in today's …
Published in Journal of Computer Technology & Applications · Vol. 16, Issue 1, 2025 · pp. 50–54 Read article
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An Analysis of the Impact of School Leadership Styles on the Morale of Teachers and Students Achievements in Nigerian Secondary Schools
Abstract: This study examines how school leadership styles affect student achievement and teacher morale in secondary schools in Nigeria. Given the challenges faced by the Nigerian education system, such as inadequate resources, large class sizes, and socio-economic disparities, the role of effective leadership in shaping educational outcomes is of paramount importance. The research focuses on analyzing how various leadership styles—transformational, transactional, and authoritarian—affect both teacher motivation and student performance in secondary …
Published in International Journal of Education Sciences · Vol. 2, Issue 1, 2025 · pp. 14–28 Read article
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Adolescent’s Adjustment to Family Dynamics in Delhi: A Comparative Analysis by Gender
Abstract: This study examined adolescents' adjustment to their family environments, drawing on a sample of 200 participants (100 boys and 100 girls), aged 16 to 18 years, selected through convenience sampling from the Delhi region. Data was collected using the "Family Environment Inventory" and the "Adjustment Inventory for School Students" (1993). Statistical analysis was performed using SPSS 26, applying tools such as mean, standard deviation (SD), t-tests, and Pearson’s Product Moment …
Published in International Journal of Children · Vol. 2, Issue 1, 2025 · pp. 20–26 Read article
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A Brief Review On Nanoparticles Drug Delivery System Used In Cervical Cancer
Abstract: Among cervical tumor-related deaths worldwide, cervical cancer is a major cause. The limitations of traditional methods, such as chemotherapy and radiation therapy, stem from their adverse effects and increased susceptibility to medications. Despite being seen as innovative options, immune checkpoint inhibitors (ICIs) have rather low clinical response rates. Reliable treatments for patients with metastatic or recurring cervical cancer are currently lacking. Lately, nanomaterials including polymers, liposomes, and dendrimers have been …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 30–40 Read article