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296 articles for “Clinical Practice”
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Impact of Topical Pure Honey Application on Radiation-induced Oral Mucositis in Patients Receiving Radiation Therapy
Abstract: This quasi-experimental study assessed the effects of pure honey on radiation-induced oral mucositis in patients with head and neck cancer undergoing radiation therapy in Kottayam. The primary objectives were to evaluate the severity of oral mucositis in both experimental and control groups, determine the effectiveness of honey in alleviating symptoms, and examine the relationship between mucositis severity and selected demographic variables. Utilizing Bertalanffy’s General System Model as a conceptual framework, …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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Development of Novel Polymeric Articulating Papers for Enhanced Occlusal Contact Assessment in Dentistry
Abstract: Traditional articulating papers, a mainstay in occlusal analysis, often exhibit limitations in consistency and difficulty with quantitative data analysis. This study explores the development of novel articulating papers utilizing advanced polymeric materials. These novel papers aim to address the shortcomings of traditional options by potentially improving: (1) sensitivity and resolution for capturing occlusal contacts, (2) consistency and reproducibility of contact readings, and (3) durability and reusability. The successful development of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1004–1011 Read article
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Leveraging Genome-Wide Association Studies for Precision Medicine in Cardiovascular Diseases
Abstract: Cardiovascular diseases (CVDs) are the leading cause of death globally, with complex etiologies involving genetic, environmental, and lifestyle factors. Genome-wide association studies (GWAS) have significantly advanced the understanding of genetic underpinnings of CVDs by identifying numerous risk loci and variants associated with various cardiovascular conditions. This review explores the potential of GWAS to drive precision medicine in cardiovascular diseases by linking genetic data with clinical outcomes, providing insights into disease …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 1, 2025 · pp. 35–39 Read article
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The Association Between Intergenerational Trauma, Perceived Social Support and Post Traumatic Growth among Young Adults
Abstract: This study explores the intricate relationship between intergenerational trauma, perceived social support, and post-traumatic growth (PTG) among young adults in the Indian subcontinent. Drawing on a sample of 199 participants, the research examines how adverse childhood experiences (ACE) transmitted across generations impact individuals' psychological well-being and their capacity for growth. In particular, the study looks into how perceived social support from friends, family, and other people can help to moderate …
Published in International Journal of Children · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Understanding Leukemogenesis: Challenges and Advancements in Diagnostic Approaches
Abstract: Leukaemia development, or leukemogenesis, is a multifactorial process driven by a complex interplay of environmental, genetic, and epigenetic factors. Despite substantial advancements in technology and medicine, which have enhanced our understanding of the contributing factors, early and accurate diagnosis remains a major challenge due to the overlapping clinical features shared by the various leukaemia subtypes. This study explores the molecular and cellular mechanisms underlying leukemogenesis, while also addressing the difficulties …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 1, 2025 · pp. 11–22 Read article
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Molecular Mechanisms of Drug Metabolism in Anesthesia: A Pharmacogenomic Perspective
Abstract: Pharmacogenomics studies how a person’s genetic profile affects their reaction to drugs, which is vital in anesthesia. Anesthetic pharmacology depends significantly on drug metabolism, which involves complex biochemical processes that manage the absorption, distribution, metabolism, and excretion (ADME) of anesthetic drugs. The cytochrome P450 (CYP) enzyme family plays a critical role in the metabolism of various anesthetic drugs, with genetic polymorphisms leading to inter-individual variability in drug responses. Specific CYP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 90–95 Read article
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Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
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Evaluating the Role of Platelet Indices, with a Focus on Immature Platelet Fraction (IPF), in Differentiating Hyper-Destructive and Hypo-Productive Thrombocytopenia: A Study from Ludhiana, Punjab, India
Abstract: Background: Thrombocytopenia, characterized by a reduction in platelet count, is commonly observed in clinical settings. Its etiology can be broadly classified into hyper-destructive thrombocytopenia, where platelets are destroyed at an accelerated rate, and hypo-productive thrombocytopenia, where platelet production is impaired. Differentiating between these two causes is essential for effective management. The Immature Platelet Fraction (IPF) has emerged as a promising non-invasive diagnostic tool to distinguish these causes. Objectives: The primary …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 Read article
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A Python-Based Investigation of Clinical Data and Ultrasound Images for PCOS Diagnosis
Abstract: PCOS is a common endocrine disorder that impacts women in their reproductive years characterized by irregular menstrual cycles, hyperandrogenism, and polycystic ovaries. The full diagnostic plan is mainly a combination of a pelvic ultrasound besides blood tests of specific parameters that indicate the presence of PCOS. Since PCOS is a hard-to-diagnose widespread hormonal disorder, blood tests, symptoms, and other parameters with the help of a computer can form a new …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Predictive Modeling of Polymer Composites for Medical Implants Using Artificial Intelligence Techniques
Abstract: The use of polymers in biomaterials was now key to designing the next generation of medical implants, which need to be strong and also compatible with living tissue. Tests for biocompatibility, such as those done in the laboratory and by doing experiments on animals, require much time and many resources, so the need for computer-based approaches becomes clear. An artificial intelligence approach was provided in this study to determine how …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 665–692 Read article
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A Single Case Report of Sacral Nerve Stimulation in Neurogenic Bladder Dysfunction: A Physiotherapeutic Perspective
Abstract: Background: This case study evaluates the effectiveness of sacral nerve stimulation (SNS) for improving neurological bladder function in a 34-year-old male patient, who underwent surgical intervention at the level of L4 for Conus Medullaris Syndrome. The patient presented with severe neurological deficits including bladder dysfunction. Method: Post-surgery, a targeted physiotherapy regimen, including faradic current stimulation to the sacral nerves (S2-S4) and conventional exercises was implemented to address bladder function. Pre- …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 1–9 Read article
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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Early Disease Detection Using Artificial Intelligence
Abstract: Growth in artificial intelligence and machine learning now make it possible for the healthcare sector to be totally transformed by a new chapter, particularly in the era of medical image analysis. This study focuses on harnessing these advancements to develop a sophisticated model for early disease detection across diverse medical domains, majorly in skin disease. By integrating diverse datasets and leveraging advanced algorithms, our methodology aims to identify subtle disease …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 3, 2024 · pp. 11–19 Read article
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Alzheimer’s Disease Classification Based on Transfer Learning of New-CNN Model
Abstract: The long-term, irreversible brain disorder “Alzheimer’s disease (AD)” currently has no known cure. Nonetheless, current medications may impede their advancement. Globally, those over 65 are the primary population affected by Alzheimer’s disease. Accurate detection of this condition requires early diagnosis. Because there are so many people who come with an ailment, manual diagnosis by health specialists is laborious and prone to error. Early detection of AD is a difficult undertaking …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 16–23 Read article
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Impact of Diabetes on Quality of Life of Patient with Diabetes in West Tripura
Abstract: Throughout the new millennium, diabetes mellitus is on the rise everywhere. According to IDF, the prevalence of diabetes in worldwide was 537 million in 2021; this number is anticipated to climb to 643 million by 2030 if no effective preventative measures are introduced. According to an IDF research, one in three households has diabetic patients, and one in seven adult diabetics worldwide lives in India. India's percentages were 9.3% in …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 2, 2025 · pp. 17–28 Read article
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Shaping Views: Nursing Students’ Perception Towards the Profession
Abstract: Nurses play a vital role in the healthcare system, providing essential care across diverse populations. As the backbone of health services in the 21st century, the nursing profession demands skilled practitioners who contribute significantly to patient care, health promotion, and disease prevention. However, global shortages of nursing professionals, particularly in countries like India, threaten healthcare quality and accessibility. Understanding nursing students’ perceptions of their profession is crucial, as these views …
Published in Journal of Nursing Science & Practice · Vol. 15, Issue 3, 2025 · pp. 1–10 Read article
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Study to Assess the Effectiveness of Teaching Program on Knowledge Regarding Management of Patients with Regenerative Orthopedics Procedures Among Orthopedic Nurses at Selected Orthopedic Departments
Abstract: Regenerative therapy is an emerging treatment approach in medical science. It focuses on the use of stem cell therapy, biological treatments, tissue engineering, platelet-rich plasma, prolotherapy, and nutraceutical supplements to replace or restore dysfunctional structures or organs. Regenerative therapy emphasizes the body’s natural healing process; it supports physiological healing mechanisms and repairs damaged tissues. It is a minimally invasive approach with expanding applications across various medical fields, including surgery, degenerative …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 7–11 Read article
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A Systematic Review on The Role of Artificial Intelligence in Assisted Reproductive Technology
Abstract: Artificial Intelligence (AI) has significantly transformed Assisted Reproductive Technology (ART) over the past five years, enhancing diagnostic accuracy, treatment personalization, and overall success rates. AI-driven algorithms and machine learning models have been integrated into various aspects of ART, including sperm selection, embryo grading, and predicting implantation success. Deep learning techniques have improved image-based embryo assessment, reduced human subjectivity and increased efficiency. Additionally, AI-powered predictive analytics have helped optimize ovarian stimulation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 4, Issue 1, 2026 Read article
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article
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Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article