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1283 articles for “cause and effect”
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Molecular Docking-Based Analysis of Rauvolfia serpentina Alkaloids Targeting HPV E1 and L1 Proteins for Antiviral Therapeutic Potential
Abstract: Human papillomavirus (HPV) is a major cause of cervical cancer and other epithelial cancers. E1 and L1 proteins are crucial to the virus's lifespan. E1 is a viral helicase that is needed for HPV DNA replication, and L1 is the main structural capsid protein that builds the virion and infects target cells. Going after these proteins is a good way to stop viruses from spreading. In this case, Rauvolfia serpentina, …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 100–113 Read article
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Urinary Tract Infection (Tadiya-e-Majra-e-Baul) in Unani System of Medicine
Abstract: In classical Unani system of medicine Tadiya-E-Majra-e-Baul. (Urinary Tract Infection) comes under the heading of Hirqatul-baul (burning micturition) which is caused by obstruction in Urinary Tract due to stone, Jisme Gharib (foreign body) Ghaliz Ghost (Badgosh), Hamal (Pregnancy), and Characterized by frequency of micturition, urgency of micturition, burning micturition and anuria . It is an Unani Medicine of Shora Qalmi, Rewand Chini and Kababchini. Having safe and good result in …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 34–39 Read article
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Flavonoids Regulate Airway MUC5AC Mucin Expression through Modulation of Multiple Signalling Pathways
Abstract: Airway mucus is a component of pulmonary innate immune function and plays very important role in defense against invading pathogenic microbes, chemicals and particles. The protective function of airway mucus is attributed to the viscoelasticity of mucins. Mucins are large glycoproteins play important role in cell–cell adhesion, airways protection, Nuclear-factor kappa B signalling, epidermal growth factor receptor signalling. Eleven mucin genes (among twenty identified mucin genes) have been expressed at …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 7, Issue 3, 2017 · pp. 21–33 Read article
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Yogic Effect on Diabetic Disorder
Abstract: Diabetes is a chronic non-communicable disease which generally starts over a period of long period of time and even in the absence of any symptoms that’s why it is called as silent killer. It is a life threatening disease which has no permanent cure. A diabetic patient is always dependent on medicine and insulin. Yoga is a means of balancing and harmonizing the mind, body and emotions. Full of restrictions …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 8, Issue 2, 2021 · pp. 47–52 Read article
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TiO2 Refined Flux Provides Significant Impact on Saw Bead Shape, Particle Size, and Hardness
Abstract: This experiment is very interested in how adding titanium dioxide powder to submerged arc welding on low alloy steel plates affects the bead geometry, grain size, and hardness. The commercial fluxes were combined with powdered titanium dioxide at varying concentrations (2.5%, 5%, 7.5%, 10%, and 12.5%). No changes were made to the welding process parameters despite the variety of welding situations. It has been shown that the inclusion of titanium …
Published in Journal of Polymer & Composites · Vol. 11, Issue 4, 2023 · pp. 70–80 Read article
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The Impact of Arthritis on Quality of Life: A Comprehensive Review
Abstract: Arthritis, a group of over 100 joint disorders, is characterized by chronic inflammation that leads to pain, reduced mobility, and disability. As the aging global population grows, the prevalence of arthritis, particularly osteoarthritis (OA) and rheumatoid arthritis (RA), continues to rise. Significant psychological, social, and financial difficulties are among the many ways that arthritis affects quality of life (QoL), in addition to physical health. Joint stiffness, discomfort, and deformities that …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 48–52 Read article
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Enhancing Surface Roughness of Polylactic Acid (PLA) 3D-Printed Parts Using CO₂ Laser Scanning: An Experimental Study on Parameter Optimization
Abstract: Fused deposition modeling (FDM) of polylactic acid (PLA) often suffers from poor surface finish due to the inherent layer-by-layer deposition process, limiting its use in high-precision applications. This study investigates CO₂ laser scanning as an efficient post-processing technique to reduce the surface roughness (Ra) of PLA parts while maintaining structural integrity. Specimens (100 × 80 × 5 mm) were fabricated with varying infill densities (35%, 70%, and 100%) to assess …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 503–511 Read article
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Optimization of Sustainable Electrochemical Machining Parameters for Polymer based Materials Using AHP Integrated TOPSIS Method
Abstract: The current paper describes the use of the AHP-TOPSIS method to optimize process parameters in sustainable electrochemical machining of polymer composites. Combine lightweight polymer matrices with reinforcing particles or fibers such as TiB₂, SiC, or Al₂O₃, offering high strength-to-weight ratio, corrosion resistance, and design flexibility, making them ideal for aerospace and automotive applications. Non-conductive and heterogeneous nature poses challenges during electrochemical machining, as it affects current distribution and material removal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1048–1059 Read article
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An Intelligent Fuzzy Based Framework for Prediction of Heart Diseases
Abstract: Coronary illness conclusion is a confusing procedure and requires an abnormal state of aptitude. In the space of medicinal analysis, there are various factors that influence the choice procedure along with these lines causing the distinctions in the assessments of the experts. There are numerous questionable hazard factors, so at times ailment conclusion is hard for specialists. Having huge numbers of components to dissect to analyze the infection of the …
Published in Journal of Advances in Shell Programming · Vol. 6, Issue 1, 2019 · pp. 1–7 Read article
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Network Pharmacology and Molecular Docking Approach to Reveal the Underlying Mechanisms of Isorhamnetin in the Treatment of Lymphangitis Carcinomatosis
Abstract: Objective: Lymphangitic carcinomatosis (LC) is a tumor that spreads through lung lymphatics and is most commonly seen secondary to adenocarcinoma. In the majority of cases, LC is a result of tumor cells spreading through the lymphatic system. However, approximately 20% of LC cases can be attributed to lymphangitis caused by tumors obstructing lymphatic drainage. This blockage commonly occurs near the lung hilum, where a centrally located mass can cause inflammation …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 28–45 Read article
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Gene Therapy in Modern Medicine: Promises and Challenge in Treating Genetic Diseases
Abstract: Gene therapy is a medical approach that focuses on altering or adjusting an individual’s genes to treat or prevent illnesses. The aim is to repair faulty genes or insert new ones into the body to combat diseases. Gene therapy can involve directly introducing modified or new genes into a patient’s cells or altering the genes already present in the patient’s body. This approach shows potential for treating a range of …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 27–32 Read article
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Quinine: Past, Present, and Future Perspective in Malaria and Autoimmune Disorder
Abstract: Quinine, a natural alkaloid extracted from the bark of the cinchona tree, has traditionally played a key role in treating malaria, a disease caused by parasites of the Plasmodium genus. Since its discovery in the 17th century, quinine has evolved from a rudimentary treatment to an essential component of modern antimalarial therapies. This article explores the historical use of quinine in the fight against malaria, its role in current treatment …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 24–33 Read article
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Effects of non-motorized vehicle on speed-density relationship of an urban intersection
Abstract: The study investigated the influence of non-motorized vehicle (NMV) in the heterogeneous traffic in terms of speed–density (v-k) relationship. The traffic of a busy intersection of Dhaka city was studied, conducted traffic survey, and modelled using VISSIM software. Three traffic scenarios, existing traffic (M1), 20% increase of NMV (M2) and 50% increase of NMV (M3) were simulated. Then, the dataset was used to model the linear v-k relationship. The v-k …
Published in Trends in Transport Engineering and Applications · Vol. 8, Issue 1, 2021 · pp. 22–29 Read article
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External Filtering and Wavelet Domain Thresholding-based Denoising Method for AWGN corrupted imagesExternal Filtering and Wavelet Domain Thresholding-based Denoising Method for AWGN corrupted images
Abstract: In this work an image de-noising method with external bilateral filtering and wavelet domain thresholding has been proposed. In Gaussian filtering, it fails to denoise an image at edges where the spatial variations are not smooth and causesblurs at the edges in the image. External bilateral filter (EBF) beats this by filtering the picture in both reach and area (space). Respective separating is a nearby, nonlinear and non-iterative procedure which …
Published in Journal of Image Processing & Pattern Recognition Progress · Vol. 8, Issue 1, 2021 · pp. 11–19 Read article
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Homology Modeling of tRNA-dependent Amidotransferase from Malaria Parasite
Abstract: Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 Malaria is one of the most prevalent diseases in the world. The causative agent of malaria is a protozoan named Plasmodium. Many drugs have been invented against malaria parasite but increasing resistant against existing drugs necessitates the discovery of many new drugs. Plasmodium parasite is the member of apicomplexan group which harbor a plastid, apicoplast. The machinery of apicoplast protein synthesis …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 2, Issue 1, 2012 · pp. 11–15 Read article
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In Silico Screening and Evaluation of Some Metabolites from Momordica charantia in the Treatment of Peptic Ulcers
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology · pp. 5–13 Read article
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article
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Chemical Treatment Methods for Types of Chemical and Environmental Pollution: Review
Abstract: Developed countries have witnessed the industrial revolution and technological advancements, as a result, environmental pollution is steadily increasing, negatively impacting living organisms and life sources. The causes are well known, as are the solutions, but major industrialized nations are procrastinating and postponing implementation of solutions because it reduces their profits. To address chemical pollution: reducing the use of nuclear energy, disposing of chemical waste in proper ways, and focusing on …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 2, 2025 · pp. 53–60 Read article
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IN SILICO SCREENING AND EVALUATION OF SOME METABOLITES FROM MOMORDICA CHARANTIA IN THE TREATMENT OF PEPTIC ULCERS
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 1, 2021 · pp. 5–13 Read article
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Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle weakness. This protein is seen in sarcolemma, Z disks in skeletal muscles, hemidesmosomes in skin and cardiac muscles giving stability to cytoskeleton, playing a crucial role in neuromuscular transmission …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 22–34 Read article