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112 articles for “treatment of tumor”
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Review of Oral Propranolol Therapy for Infantile Hemangioma
Abstract: Infantile hemangioma, or called as strawberry hemangioma, is the most common vascular tumor in infancy. Although most will resolve, the rest of IHs are significantly worrisome; some can ulcerate or even grow at an unpredictable rate, which leads to disfigurement and dysfunctional body parts. The treatment should be focused on prevention of life-threatening complications, prevention of permanent scarring, and avoidance of aggressive treatments; these are the goals of management. This …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 1, 2019 · pp. 25–29 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Harnessing Nature: Formulations for Colon Cancer Prevention and
Abstract: Colon cancer, a rapidly advancing disease worldwide, involves the carcinogenesis of the distal part of the intestine. This malignancy progresses through various developmental stages necessitating diverse treatment approaches. Traditional treatments include drug therapy and chemotherapy; however, emerging methods, such as the use of phytochemical compounds offer promising mechanisms for combating this disease. Phytochemical compounds derived from natural food sources, including flavonoids, tannins, resveratrol, and epigallocatechin-3-gallate, exhibit potent anti-cancer properties. They …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 11–23 Read article
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A Rare Case Of Symplastic Leiomyoma Of Uterus : A case Report
Abstract: Uterine smooth muscle tumors (USMT) are of mesenchymal origin and develop from the smooth muscle cells of the uterus. Leiomyomas and their subtypes are the most commonly occurring USMT’s. Symplastic Leiomyoma is an unusual histologic subtype of Benign Leiomyoma, hence also known as atypical or Bizarre leiomyoma. It is often difficult to differentiate it from Leiomyosarcoma because of its bizarre looking nuclei on histology. However it’s malignant transformation is rare. …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 26–31 Read article
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Evaluating Andrographis paniculata Phytochemicals as Potential Glioma Therapeutics via Molecular Docking Approach
Abstract: Evaluating Andrographis paniculata Phytochemicals as Potential Glioma Therapeutics via Molecular Docking ApproachGlioneuronal tumors and gliomas are grade I tumors classified by the World Health Organization (WHO). They typically grow slowly and primarily affect infants, children, and teenagers, but can also occur in adults. They mostly cause seizures caused by gangliomas. Most current treatments include surgery and radiotherapy. Since this disease affects children, the current treatments may cause complications. Andrographis paniculata …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 82–93 Read article
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Unlocking Potential: Capecitabine’s Evolution as an Anticancer Wonder Drug
Abstract: Capecitabine, a precursor to 5-fluorouracil (5-FU), is Anticancer Drug in treating solid tumors like colorectal, breast, and gastric cancers. Its mechanism involves converting to 5-FU mainly within tumor cells, reducing toxicity while maximizing effectiveness. Besides being effective alone, it is also valuable in combination therapies, showcasing its versatility in cancer treatment. This review explores the transformative journey of capecitabine as a pivotal anticancer drug. Beginning with an introduction to its …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 17–24 Read article
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Automated System for Reduction of Muscle Inflammation after an Injury
Abstract: AbstractThe therapeutic applications have equally gained more importance with that to surgeries in orthopedics. The main reason for pre-operative therapeutic methods on muscles deals in reducing the benign and malignant tumors, called as lesions. This is carried out with cryotherapy, which is the reliable, safer and cost-effective technique used. At first the ice packs and ice gel being applied to the area under treatment which could reduce the lesions and …
Published in Recent Trends in Electronics Communication Systems · Vol. 5, Issue 2, 2018 · pp. 7–12 Read article
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The Quiet Intruder: An Insidious Presentation of Primary Plasma Cell Leukemia and a Literature Review on Current Treatment Strategies
Abstract: Introduction: Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell dyscrasia, defined by ≥5% circulating plasma cells, with poor prognosis and rapid progression. Case Presentation: A 66-year-old African–American female with no prior medical history presented with one week of fatigue, dehydration, and polydipsia. Laboratory evaluation revealed leukocytosis, severe thrombocytopenia, acute kidney injury (creatinine 4.03 mg/dL), and hypercalcemia (13.0 mg/dL) with suppressed PTH. Imaging showed intra-abdominal lymphadenopathy without …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 1–5 Read article
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Change of Capacitance in Cancerous Cell
Abstract: Cancer is a genetic disease. It is characterized by out of control growth of cell. It harms the body with its uncontrollable growth. Tumors that do not spread and show limited growth are generally considered to be benign. More dangerous are malignant tumors which can manage to divide and grow. They may be very dangerous and may cause death. Early detection of the disease helps in treatment and may save …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 4, Issue 1, 2015 · pp. 29–32 Read article
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CTCHFA: Discovery of Circulating Tumor Cells in Metastatic Breast Cancer and Nonmetastatic Cancer by using Novel Hybrid Hierarchical Clustering Algorithm in Firefly Distance
Abstract: AbstractBlood testing for circulating tumor cells (CTCs) has emerged as one of the highest fields in cancer research. CTC detection are an early gene marker of reaction to systemic therapy, whereas their molecular characterization has a strong field that can be translated to individualized targeted treatments and spare breast cancer (BC) patients from unnecessary and ineffective therapies. Genomic research regarding CTCs monitoring for BC is limited due to the lack …
Published in Journal of Computer Technology & Applications · Vol. 6, Issue 1, 2015 · pp. 9–18 Read article
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Personalised Cancer Vaccination Strategies: Bridging Genomics, Bioinformatics, and Immunotherapy
Abstract: Immunotherapy has revolutionized cancer treatment by harnessing the body’s immune system to detect and destroy cancer cells. Personalised cancer vaccines are one of the most promising options because they could allow treatment to be based on the specific tumour profile of each person. The goal of these vaccines is to make the immune system recognise and fight cancer-specific antigens, which will lead to strong and long-lasting anti-tumor responses. However, moving …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Brain Tumor Detection Using RestNet50 Architecture
Abstract: This paper presents a novel deep learning model for brain tumor diagnosis from MRI scans on the basis of ResNet50 with some modifications. Optimizing the modified layers and pre-trained ResNet50 for improved diagnostic accuracy and reliability in real-world clinical settings is one of the key contributions of this paper. The model was trained on an extremely well-balanced data of 2,577 MRI scans, which were split equally among the tumor and …
Published in Current Trends in Signal Processing · Vol. 15, Issue 2, 2025 · pp. 1–13 Read article
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Nutraceuticals as Adjunctive Treatment in Cancer Exploring Efficacy and Mechanism of Action
Abstract: Dietary habits are a critical factor in cancer prevention, with plant-based diets rich in vegetables and fruits associated with reduced cancer risk. Nutraceuticals—bioactive compounds derived from food and supplements—have gained attention for their potential in cancer prevention and therapy. Phytochemicals such as flavonoids, polyphenols, and alkaloids exhibit anti-cancer properties through mechanisms including antioxidant activity, anti-inflammatory effects, inhibition of tumor growth, and induction of apoptosis. Key nutraceuticals include alkaloids (e.g., caffeine, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 35–45 Read article
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A Review of Literature on Breast Cancer: Molecular Insights, Clinical Approaches, and Future Perspectives
Abstract: Breast cancer is the leading cause of morbidity and mortality in women globally. Although both men and women can get the condition, women are more likely to get it, and its prevalence has been rising globally in recent years. The epidemiology, risk factors, pathophysiology, diagnosis, treatment options, and survival rates of breast cancer are all examined in this review of recent research. Breast cancer can show up as a lump …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 15–20 Read article
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Ushering Era of Nanomedicines: A Short Review
Abstract: Nanomedicine is a revolutionary field of nanotechnology and it is extending very rapidly with every passing day. This field is focusing on the developing of the nanoparticles for the diagnosing and treatment of patient’s diseases. It is also in the field of therapeutic and prophylactic applications. Nanoparticles have unique properties that we used in medicines for the treatment. Nanomedicines prefer over other medicines because of the extraordinary properties of nanoparticles …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 3, 2019 · pp. 1–8 Read article
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Gene prioritization of colorectal cancer using computational approach
Abstract: Colorectal cancer (CRC) continues to be a major worldwide health issue, underscoring the need to pinpoint crucial genetic elements influencing its initiation and advancement. In this investigation, we utilize sophisticated computational methods to prioritize potential genes linked to CRC development. Through the utilization of various bioinformatics tools and comprehensive methodologies, we systematically examine extensive microarray datasets to identify potential genetic contributors. Initially, a vast amount of CRC microarray data (approximately …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 39–52 Read article
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Biopolymer-Based 3D Composite Scaffolds for Bone Tissue Engineering: Photothermal-Responsive Systems with Controlled Pt (IV) Prodrug Release
Abstract: Biopolymer-based composite scaffolds have attracted significant attention as multifunctional platforms at the intersection of polymer science, regenerative medicine, and cancer nanotherapy. In this study, a dual-functional scaffold was developed for simultaneous osteosarcoma treatment and bone regeneration using poly (L-lactic acid) (PLLA) reinforced with bioactive glass (BG) and integrated with a glutathione-responsive platinum (IV) prodrug system (PDA@Pt). To improve interfacial adhesion, photothermal conversion efficiency, and tumor-specific activation, the Pt (IV) prodrug …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 351–361 Read article
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Targeting TNFSF4 in the Management of Systemic Lupus Erythematosus
Abstract: Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that remains a significant challenge for both healthcare providers and researchers. Despite advances in understanding its mechanisms, finding effective therapies is still difficult. This review highlights a potential therapeutic target in SLE research: tumor necrosis factor superfamily member 4 (TNFSF4), also referred to as OX40L. We explore how TNFSF4 contributes to SLE development, looking at its role in immune system regulation …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 6–14 Read article
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An Evaluation of Photodynamic Therapy in Dentistry with a Focus on Surgical Applications
Abstract: Throughout the centuries, various forms of light therapy have found applications in medical settings. These include phototherapy for neonatal jaundice, psoralen molecules combined with ultraviolet A light (PUVA) in dermatology, and techniques like photodynamic therapy (PDT) and photodetection. In recent years, the emergence of antibiotic-resistant strains, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis, has necessitated the exploration of alternative treatment options. Photodynamic antimicrobial chemotherapy (PACT) has arisen as …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 3, 2023 · pp. 1–9 Read article