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340 articles for “outcomes”
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STRUCTURAL–EPIGENOMIC ATLAS: CNV/SV- DRIVEN PROGNOSTIC REFINEMENT ACROSS CANCERS
Abstract: Structural genomic alterations, including copy number variations (CNVs) and structural variants (SVs), play a central role in cancer initiation and progression. These alterations extend beyond gene dosage effects and interact dynamically with epigenomic mechanisms such as DNA methylation, histone modifications, and three-dimensional chromatin organization. Recent pan-cancer studies have demonstrated that CNV burden and SV signatures reflect key oncogenic processes including chromothripsis, homologous recombination deficiency, enhancer hijacking, and extrachromosomal DNA (ecDNA) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Swachhata Hi Seva: Transforming Public Health, Environmental Sustainability, and Water Stewardship Through Community Engagement
Abstract: Swachhata (cleanliness) is not merely a hygiene practice but a foundational driver of public health, environmental resilience, and sustainable development. Recognizing its multidimensional importance, this research critically examines the “Swachhata Hi Seva” campaign as a transformative, community-led movement that elevates cleanliness from an individual responsibility to a collective civic duty and social commitment. The study highlights how the campaign mobilizes diverse community groups, institutions, and local governance structures to actively …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 4, Issue 1, 2026 · pp. 9–15 Read article
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The Hidden Struggle: Premenstrual Depression its Impact on Women’s Health and Management Strategies: A Narrative Review.
Abstract: Background: Premenstrual depression, including Premenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), represents a significant yet underrecognized contributor to women’s mental health burden. Hormonal fluctuations during the luteal phase interact with neurotransmitter systems, particularly serotonin and GABA, leading to affective and somatic symptoms that impair daily functioning. Objective: This systematic review synthesizes evidence on the prevalence, pathophysiology, psychological impact, and management strategies of premenstrual depression among reproductive-aged women, with particular …
Published in International Journal of Nutritions · Vol. 3, Issue 1, 2026 · pp. 21–32 Read article
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Challenges And Constraints Affecting Female-Owned Rural Farm Businesses in Plateau State, Nigeria
Abstract: This study examined the challenges and constraints affecting female-owned rural farm businesses in Plateau State, Nigeria. No prior study had conducted a comprehensive, quantitative, state-wide investigation covering all 17 local government areas (LGAs) of the state, and this study addressed that gap. The objectives were to identify the challenges faced by female-owned rural farm businesses, assess their relationship with business performance, and determine how strongly these challenges predicted performance outcomes. …
Published in International Journal of Rural and Regional Development · Vol. 4, Issue 1, 2026 · pp. 1–13 Read article
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Early Life Nutrition as a Determinant of Long-Term Vaccine Immunogenicity in Livestock: Mechanisms, Practical Strategies, and Species-Specific Considerations
Abstract: Early life represents a critical period for immune system development in livestock, during which nutritional exposures can exert long lasting effects on vaccine immunogenicity. Although vaccination is a cornerstone of infectious disease control in food producing animals, marked variability in vaccine induced immune responses is frequently observed under commercial conditions. Growing evidence suggests that this variability is partly driven by differences in early nutritional status, which can influence immune maturation, …
Published in International Journal of Vaccines · Vol. 3, Issue 1, 2026 · pp. 15–26 Read article
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Drug Marketing in Tropical Regions and Its Effect on Pharmacovigilance Awareness and Reporting
Abstract: Drug marketing practices in tropical regions present a complex interplay between pharmaceutical promotion, healthcare infrastructure limitations, and public health outcomes. These regions – characterized by high disease burden, socio-economic disparities, and diverse healthcare delivery systems – often experience unique challenges in ensuring safe and rational drug use. Aggressive and sometimes unregulated marketing strategies by pharmaceutical companies may significantly influence prescribing behavior, patient compliance, and, ultimately, pharmacovigilance systems. Pharmacovigilance, defined as …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 · pp. 1–17 Read article
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Predictive Analytics for Student Well-Being and Occupational Success
Abstract: The integration of predictive analytics into higher education has significantly transformed institutional decision-making processes. However, prevailing implementations remain predominantly performance-centered, focusing on dropout prediction and grade forecasting rather than holistic developmental outcomes. Concurrently, higher education systems worldwide are confronting escalating concerns regarding student mental health, disengagement, career uncertainty, and labor market volatility. These intersecting challenges necessitate a broader theoretical reconceptualization of predictive analytics—one that integrates psychological well-being and long-term occupational …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 155–163 Read article
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Evaluating an ai-supported experiential learning intervention: a quasi-experimental study of the joyful saturday model for student engagement and holistic development
Abstract: Student disengagement, declining academic motivation, and passive classroom participation remain major challenges in modern higher education systems. Traditional lecture-based teaching methods often fail to accommodate diverse learning styles and do not sufficiently promote active participation or collaborative learning. To address these challenges, the present study evaluates the effectiveness of Joyful Saturday, a structured experiential learning initiative designed to improve student engagement, motivation, and holistic development through interactive academic activities supported …
Published in International Journal of Behavioral Sciences · Vol. 3, Issue 1, 2026 · pp. 79–88 Read article
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Impact of Pre-Operative Nebulized Lidocaine–Dexmedetomidine Combination Versus Monotherapy on Incidence, Severity, and Patient Comfort Scores of Post-Operative Sore Throat: A Randomized Controlled Clinical Trial
Abstract: Post-operative sore throat (POST) is a common issue after endotracheal intubation and can reduce patient comfort and hinder recovery. This randomized, double-blind clinical study investigated how effective pre-operative nebulized lidocaine, dexmedetomidine, and their combination are in minimizing POST. Eligible adult patients classified as ASA I–II and scheduled for elective surgery under general anesthesia were randomly assigned to three groups. Nebulization was administered 15–20 minutes before induction using standardized dosing and …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 4, Issue 1, 2026 · pp. 29–35 Read article
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AI-Driven Pharmacogenomics and Precision Medicine: Future of Personalized Therapy
Abstract: Pharmacogenomics and artificial intelligence (AI) are emerging as important drivers of precision medicine, enabling healthcare systems to adopt individualized therapeutic approaches. Pharmacogenomics examines how genetic variations influence drug response, efficacy, metabolism, and toxicity, while AI provides advanced computational tools for analyzing complex genomic and clinical data. This review highlights the integration of AI-driven pharmacogenomics in personalized therapy and its potential to improve treatment outcomes. Machine learning, deep learning, natural language …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 2, 2026 · pp. 1–12 Read article
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Cost Model of Acquisition and Merger in Construction Industry
Abstract: Merger and Acquisition in India is at an all-time high with more buyers now than before; it has been accounting for 80% of closed deals in 2020–2021, up from 70% in 2017–2019. To determine the Merger and Acquisition of the company, this article explores the main factors in the Merger and Acquisition process. And also study the main framework of the Merger and Acquisition. And, also, the article discusses the …
Published in International Journal of Architectural Design and Planning Read article
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An Integrated Study to Extrapolate the Interaction of NMDAR with Potential Ligands for the Treatment of Alzheimer’s Disease Symptoms
Abstract: Objective: Alzheimer’s disease (AD) is the most common neurodegenerative disease affecting the health status of older adults especially those above the age of 60 years. As an outcome, two types of medications have been developed for the treatment of its symptoms which are acetylcholinesterase (AChE) and N-methyl-D-aspartate receptor (NMDAR) antagonist. This paper uses the computational approach to understand the interaction of NMDAR with four major phytocompounds (curcumin, L-epicatechin, ginsenosides, and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 15–27 Read article
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Impacts of Green Facades in Modern Era
Abstract: Modern architecture was an architectural movement or style centred on cutting-edge construction technologies, particularly the use of reinforced concrete, glass, and steel. The foundational goal of 21st century architecture is to create better structures that are inherently sustainable by utilising better materials and technologies. Facades are the outermost covering of a building which have the maximum interaction with the environment. A wall that is completely or partially covered with vegetation …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 44–57 Read article
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Assessing Workspaces of Office Buildings; A Case of Lagos Office Spatial Characteristics
Abstract: The spatial characteristics of an office space play a fundamental role in contributing to the performance of the employees who use the office space. An efficient and functional workspace should be designed to cater to the needs of employees as this is critical to their performance as well. Studies from various authors have shown that better results and outcomes are gotten from employees who are satisfied with their workspaces. Although …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 17–30 Read article
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Matching Minutiae Fingerprint Q-Learning Approach for Detail Coordination: Identifiable Mark Point
Abstract: The use of fingerprints for high-precision recognition and identification of people is one of the most reliable biometric symbols because it is non-invasive. In this paper, we propose an innovative approach to detect details on low contrast resolution image quality of fingerprint images. Existing algorithms are not very susceptible to sound and image excellence due to the lack of level of intensity. We recommend a reliable route to find fingerprints …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 1–15 Read article
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The Effectiveness of Honey Application for Oral Mucositis in Cancer Patients: A Review of Randomized Controlled Trials
Abstract: Background: Oral mucositis (OM) is a prevalent and distressing adverse outcome of cancer therapies, including chemotherapy and radiation therapy. It is an inflammatory ailment that impacts the mucous membrane inside the mouth, tongue, gums, and throat. OM can cause pain, discomfort, difficulty swallowing, and in severe cases, it can lead to infection and delayed cancer treatment. Although there are various treatments available, such as painkillers, anti-inflammatory drugs, and topical anesthetics, …
Published in International Journal of Oncological Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 32–39 Read article
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A Descriptive Study to Assess the Awareness on First Aid of Fracture Among Selected Rural Public of Mysuru
Abstract: First aid refers to the prompt care given to a person who has been suddenly ill or injured until expert help is available or until the individual has recovered. Providing initial care to an individual with a minor injury is classified as first aid, wherein the application of first aid techniques suffices for treating minor burns, wounds, and insect stings. One ailment that requires emergency care is fracture, which will …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 1–5 Read article
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Management of Rotator Cuff Injury with Physiotherapy in Pre- and Post-surgery: An Overview
Abstract: The likelihood of rotator cuff tears increases with age, with total width tears occurring in roughly 25% of people in their 60s and an extra 50% of people in their 80s. Despite the fact that surgery is considered an active therapy, repeated rips at the inset place are common, particularly during progressive tears, which are common in the elderly population. Physical therapy and exercise therapy are currently receiving more attention …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 6–12 Read article
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Thoracolumbar Spine Surgery: Peri-operative Nursing Care Needs and Quality of Life
Abstract: Aim and Objective: To explore the nursing care needs of the patients after thoracolumbar spine surgery during preoperative, post-operative, home care and to assess the quality of life. Design: An exploratory study. Methods: The study was conducted among 50 patients who had undergone thoracolumbar spine surgery in neurosurgery units of tertiary care hospital from July 2018 to September 2020. The nursing needs were assessed by interviewing participants telephonically using an …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–23 Read article
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Bone Fracture: Understanding, Therapies, and Rehabilitation
Abstract: Bone fractures are common injuries that can significantly impact an individual's quality of life. This article presents a comprehensive examination of bone fractures, encompassing their origins, categorization, and potential ramifications. This review of literature explores various therapeutic approaches and rehabilitation strategies employed in the management of bone fractures. Surgical interventions, non-surgical treatments, and rehabilitation techniques are discussed, highlighting their effectiveness in promoting healing, restoring function, and preventing complications. The article …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 24–28 Read article