Search
176 articles for “kidney”
-
Phytochemical Screening, Proximate Analysis and Acute Toxicity Study of Ethanolic Extract of Launaea taraxacifolia on Visceral Organs of Albino Rats
Abstract: Despite increase in the acceptance of herbs for the treatment of certain diseases, there are limited information on the effectiveness, safety and toxicity of herbs. In this study, proximate analysis, phytochemical screening and acute toxicity studies on the herbal recipe, Launaea taraxacifolia were carried out. Constituents of Launaea taraxacifolia were extracted using ethanol. Phytochemical screening and proximate analysis were carried out on the extract. Fifteen (15) albino rats, divided into …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 1–8 Read article
-
Protective Effect of Epigallocatechin Gallate (EGCG) on Sodium Fluoride (NaF) Induced Changes in Histology of Selected Organs in Rats
Abstract: Histopathology is the microscopical examination of biological tissues to observe the appearance of diseased cells and tissues in very fine detail. The present study, has been designed to evaluate the effects of oral administration of Sodium Fluoride (NaF) 25 mg/kg/bw (orally), NaF with EGCG (40 mg/kg/bw) daily for four weeks on histological alterations, if any on heart, liver, kidney and testes of rats. Rats were weighed about 160–180 g. NaF …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 1, 2013 · pp. 20–26 Read article
-
Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article
-
Nephrotic Problems among Diabetic Patients of Bangladesh
Abstract: Nearly 80% of people with diabetes live in low- and middle-income countries. It increases healthcare use and expenditure and imposes a huge economic burden on the healthcare systems. The International Diabetes Federation estimated more than 7 million people with diabetes in Bangladesh and nearly an equal number with undetected diabetes. This figure is estimated to be doubled by 2025. It is a costly condition and can lead to stroke, heart …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 8, Issue 3, 2018 · pp. 1–6 Read article
-
A comprehensive Review on the Impact of Aquatic Pollution on Fish
Abstract: Freshwater is one of the most important natural resources that are used for various activities in our daily lives. Here, 70% of our Nation’s liquid freshwater is unfit for consumption. Effect of heavy metals on hydrophobicity provides general information about the distribution of heavy metals in the atmosphere from different sources around the world, such as atmospheric precipitation, river and lake sediments. Human activities such as chemicals are increasing day …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–12 Read article
-
Determining the Root Causes of Complications in Hemodialysis
Abstract: As with peritoneal dialysis and kidney transplantation, hemodialysis has been considered one of the most effective therapies for the replacement of kidney function. While this helps to save patients with the disease by decreasing morbidity /mortality/ rates, this medication has some side effects. These may manifest during the dialysis process alongside the ongoing treatment. Avoiding these barriers becomes crucial for improving the patients’ prognosis in this context.We are going to …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 27–47 Read article
-
The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article
-
Protective Effects of Phyllanthus amarus and Sida acuta Extracts Against DoxorubicinInduced Toxicity in Chick Embryo Models
Abstract: Chemotherapy remains a cornerstone of cancer treatment, yet severe side effects, including cardiotoxicity often limit its clinical application. Doxorubicin, a widely used anticancer drug, is particularly associated with dose-dependent toxicities that impact the heart, liver, and kidneys. In search of complementary approaches to mitigate these adverse effects, this study evaluates the protective potential of hydro-alcoholic extracts from Phyllanthus amarus and Sida acuta, two medicinal plants with known antioxidant and anti-inflammatory …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 Read article
-
Integrating Counseling into ESRD Care: Addressing Mental Health to Enhance Patient Outcomes
Abstract: End-Stage Renal Disease (ESRD), also referred to as Chronic Kidney Disease Stage 5 (CKD-5), profoundly impacts patients' physical health as well as their emotional and psychological well-being. As individuals approach renal failure, they commonly encounter complex mental health challenges such as depression, anxiety, chronic stress, and a markedly diminished quality of life. This study underscores the critical importance of integrating emotional and mental health support into the care of ESRD …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 Read article
-
Enhanced Multimodal Disease Prediction Using Hybrid Ensemble Learning and AutoML Techniques
Abstract: The integration of hybrid ensemble learning and automated machine learning (AutoML) is revolutionizing disease prediction by addressing the complexity, imbalance, and high dimensionality inherent in medical datasets. This paper proposes an advanced pipeline that combines diverse ensemble learning models with AutoML-based optimization to predict chronic diseases such as kidney diseas-e, Parkinson’s disease, and lung cancer. Publicly available datasets from UCI and PhysioNet repositories were preprocessed using outlier removal, normalization, and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 15, Issue 1, 2026 · pp. 10–20 Read article
-
Role of Herbal Medicines in the Management of Diabetes
Abstract: Diabetes mellitus is a condition marked by elevated blood sugar levels, alterations in the metabolism of lipids, carbohydrates, and proteins, and over time, it can lead to complications affecting the eyes, kidneys, cardiovascular system, and neurological functions Many plants from throughout the world have been investigated for their potential to prevent diabetes. This review article aims to highlight some key medicinal plants with blood sugar-lowering effects supported by credible clinical …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 29–38 Read article
-
DRUG INDUCED IMMUNE MEDIATED NEPHRITIS: MOLECULAR MECHANISM , PATHWAYS AND CLINICAL IMPLICATIONS
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
-
Development of an Arduino-Based Water Quality Monitoring System Using Turbidity Sensor
Abstract: Clean drinking water is essential for human health since dirty water can lead to serious diseases such as diarrhoea, cholera and typhoid and long-term diseases such as kidney damage, cancer and child development problems. Though hard water is less dangerous, it causes dry skin and kidney stones and saline water causes high blood pressure. The Water Quality Monitoring System exists as a solution against existing water safety issues. The system …
Published in Journal of Water Pollution & Purification Research · Vol. 13, Issue 1, 2026 · pp. 26–31 Read article
-
Signal Transduction Pathways in Xenotransplantation: Insights and Implications
Abstract: In this article, we will discuss Xenotransplantation which is used for the transplantation of tissues or organs cells from one species to another species. It holds tremendous promise for addressing the clinical shortage of human organs for transplantation. In this review we provide a comprehensive analysis of the key signal transduction involved in xenotransplantation is paramount for overcoming these hurdles and advancing the field toward clinical application. Many studies on …
Published in Current Trends in Signal Processing · Vol. 13, Issue 3, 2023 · pp. 15–23 Read article
-
Studies on Development of a Super Adsorbent Polymer for the Removal of Nitrogenous Waste Products from Urine Samples and in Intestinal Fluid Simulator
Abstract: Introduction: Colonic dialysis (CD) has been proposed as an appropriate candidate for excretion of electrolytes, nitrogen waste products and excessive fluid using gastrointestinal (GI) tract. Methods: The GI environment simulated in terms of concentrations of nitrogenous waste products, electrolytes, temperature and pressure. In addition, 24-hour urine samples were obtained from 10 healthy adult volunteers. Adsorbing capacity of Super Adsorbent Polymer (SAP) evaluated in GI tract simulating system and urine samples. …
Published in Journal of Polymer & Composites · Vol. 10, Issue 2, 2022 · pp. 1–7 Read article
-
An Overview on the Management cum Treatment of Nephropathy in Type-1 Diabetes Mellitus
Abstract: The motive of this review is to keep updated with the medical nonfictions, the projected early natural arrangement of diabetic nephropathy, the theories behind the root of its pathogenesis pathophysiology, diagnosis and its supervision. Type 1 diabetes is an autoimmune disease characterized by advanced destruction of pancreatic beta cells by genetic and environmental factors which primes to an absolute necessity of insulin for survival and conservation of health; while Diabetic …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 3, 2020 · pp. 19–38 Read article
-
Effect of Jawarish Zarooni and Sharbat Buzoori in a Diagnosed Case of Nephrotic Syndrome
Abstract: Nephrotic syndrome is a manifestation of kidney disease involving the glomeruli, characterized by oedema, proteinuria, hyperlipidemia and low serum albumin. It may be caused by primary kidney disease such as focal segmental glomerulosclerosis, and mutations in the podocin gene (shown in familial and sporadic forms of steroid-resistant nephrotic syndrome). A study by Michael B. Rothenberg and Walter Heymann M. showed 5-year survey of the incidence of the nephrotic syndrome in …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 1, 2020 · pp. 33–35 Read article
-
An Investigation of Some Metals Concentrations in Freshwater Fish Collected from Wellington Lake, Tamil Nadu, India
Abstract: The present study was conducted to determine the metals of lead, cadmium, copper, chromium, iron, zinc and manganese concentrations in gill, liver, kidney, intestine and muscle of the collected freshwater fish Etroplus maculatus, Cirrhinus cirrhosa, Rastrelliger kanagurta, Macrognathus pancalus and Punitius dorsalis of the Wellington lake, Cuddalore district, Tamil Nadu, India collected during January–December 2011. Metals concentrations varied significantly depending upon the type of fish tissues and locations. In the …
Published in Research and Reviews: A Journal of Toxicology · Vol. 7, Issue 3, 2017 · pp. 6–11 Read article
-
Histotoxicity of Acid Orange 7 on organs of Fresh water fish Labeo rohita
Abstract: The present paper reports the histotoxic effects of Acid Orange 7, an azo dye on the tissues viz. gill, kidney and liver in major carp, Labeo rohita, fingerlings. The sublethal concentrations of the dye are responsible for the histopathological alterations in the target tissues. In the gills hyperplasia, epithelial lifting, hooked secondary gill lamellae, haemorrhage in the primary gill lamellae and erosion of secondary gill lamellae were seen. The kidney …
Published in Research and Reviews: A Journal of Toxicology · Vol. 1, Issue 1-3, 2011 · pp. 45–54 Read article
-
Pyrethroid Mediated Some Macromolecular and Biochemical Changes in Freshwater Teleost
Abstract: Abstract In present investigation, a freshwater fish Channa punctatus was exposed for 21 days to synthetic pyrethroid malathion at sublethal concentrations of 0.007mg L−1 and 0.093 mg L−1 that represented 10% of the 96 h LC50 of the pesticide for this fish. Tissue samples were collected at the end of the experiment and analyzed to determine oxidant/antioxidants status (catalase, LDH, DNA content, protein content, cortisol, etc.) of the fish. Enzyme …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 2, 2020 · pp. 14–21 Read article