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161 articles for “In silico”
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Fabrication and Mechanical Characterization of Hybrid Metal Matrix Composite Castings
Abstract: This work investigates and addresses the casting of a novel hybrid composite material with tungsten carbide and aluminum-silicate particles mixed at varying weight fraction rates. Production of hybrid composite has some advantages if it is processed by near net shape techniques. The simplest method for dealing with this hybrid composite is the turbulence produced by the vortex agitating technique. The vortex mixing method is used in this study to create …
Published in Journal of Experimental & Applied Mechanics · Vol. 15, Issue 3, 2024 · pp. 32–38 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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AI-Assisted Defect Detection in Polymer Composite Insulators Using an Optimised Ensemble Deep Learning Framework for Structural Health Monitoring
Abstract: Polymer composite insulators, particularly those made from silicone rubber and epoxy resins, are increasingly adopted in high-voltage transmission systems due to their superior electrical insulation, lightweight design, hydrophobicity, and environmental durability. Despite their advantages, these materials are susceptible to surface degradation, mechanical cracking, and flashover under prolonged exposure to environmental pollutants, thermal stress, and electrical aging. Accurate, real-time condition assessment of these composite insulators is critical for ensuring operational safety, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 253–261 Read article
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Enhancement of the Life of Helical Spring Systems
Abstract: Helical springs are essential mechanical factors considerably employed in automotive, aerospace, and artificial systems because of their capability to store and release energy, absorb shock, and sustain repeated weight cycles. The performance, responsibility, and durability of these springs play a vital part in ensuring the effectiveness and safety of the entire system in which they are integrated. Over time, numerous researchers have focused on strategies to enhance the service life …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 12–24 Read article
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Mechanical Characterization and Machinability Optimization of Stir-Cast Al6061–SiC Metal Matrix Composites
Abstract: This study presents the fabrication, mechanical characterization, metallurgical analysis, and machinability optimization of Aluminum 6061 reinforced with Silicon Carbide (SiC) metal matrix composites (MMCs) at three weight fractions: 5%, 7.5%, and 10%. Composites were manufactured using the stir casting technique, followed by comprehensive mechanical testing (tensile, hardness, and impact), optical microscopy, and scanning electron microscopy (SEM). Machinability was assessed through turning experiments on a lathe using an L9 Taguchi orthogonal …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Organic Solar Cell: It’s future prospect
Abstract: Organic solar cells (OSCs) are emerging as a promising frontier in renewable energy technology, distinguished by their lightweight, flexible composition, cost-effective manufacturing processes, and potential for large-scale deployment. Unlike their silicon-based counterparts, which rely on inorganic materials, OSCs harness organic molecules or polymers to convert sunlight into electricity. Their adaptability in design and production is a key strength, facilitated by the ease with which organic materials can be synthesized and …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 1, 2024 Read article
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A review on micro hot embossed Fresnel lenses
Abstract: Background: Micro replication techniques like HE allows for the large-scale manufacturing of the micro components which use polymers like Polymethyle methacrylate, Polycarbonate, polystyrene as the work material. In the hot embossing process, key parameters include applied pressure, temperature during heating, duration of embossing, and temperature during demolding. Research Objectives: Developing straightforward and affordable methods to produce the micro featured molds needed for the hot embossing is a significant research goal. …
Published in Journal of Polymer & Composites · Vol. 12, Issue 8, 2024 · pp. 12–28 Read article
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Composition and Structure of Oil Finishing Agent †
Abstract: Use of oil finishing agent is widely used in the process of production of carbon fibers to impart unusual and exceptional strength to the carbon fibers, the key load-bearing component, of the advanced materials, namely, carbon fiber reinforced composites (CFRPs). CFRPs are being widely used in the realm of aeronautics, astronautics, aeronautics, geonautics, sports equipment, and many more. However, quite often, much of the knowledge on the composition of oil …
Published in International Journal of Crystalline Materials · Vol. 2, Issue 1, 2025 · pp. 01–10 Read article
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VLSI – Power, Expansion and Versatility
Abstract: The evolution of Very Large-Scale Integration (VLSI) technology has significantly transformed the landscape of modern electronics, driving innovations across diverse industries. This article explores the key attributes of VLSI, focusing on its power, expansion, and versatility. VLSI's power lies in its ability to integrate thousands to millions of transistors on a single chip, enabling the development of high-performance, energy-efficient devices. The expansion of VLSI technology is exemplified by its application …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 1, 2025 · pp. 1–8 Read article
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Evaluating Andrographis paniculata Phytochemicals as Potential Glioma Therapeutics via Molecular Docking Approach
Abstract: Evaluating Andrographis paniculata Phytochemicals as Potential Glioma Therapeutics via Molecular Docking ApproachGlioneuronal tumors and gliomas are grade I tumors classified by the World Health Organization (WHO). They typically grow slowly and primarily affect infants, children, and teenagers, but can also occur in adults. They mostly cause seizures caused by gangliomas. Most current treatments include surgery and radiotherapy. Since this disease affects children, the current treatments may cause complications. Andrographis paniculata …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 82–93 Read article
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New trends in Radio Frequency design and making things smaller
Abstract: Recent improvements in wireless communication, the Internet of Things (IoT), and 5G/6G networks have made people want small, powerful radio frequency (RF) equipment. With an emphasis on how developments in materials engineering, circuit architecture, and packaging technologies are redefining RF system integration, this article offers a thorough evaluation of current developments in RF downsizing. System-on-Chip (SoC), System-in-Package (SiP), and Antenna-in-Package (AiP) ideas, which allow tightly integrated RF front-ends with enhanced …
Published in International Journal of Radio Frequency Innovations · Vol. 3, Issue 2, 2025 · pp. 28–34 Read article
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Recent Innovations in Semiconductor Materials for Smart Electronic Devices
Abstract: Recent advancements in semiconductor materials have significantly transformed the design, performance, and functionality of smart electronic devices such as smartphones, wearable systems, IoT devices, autonomous systems, and biomedical electronics. With the continuous demand for higher processing speed, lower power consumption, improved thermal stability, and extreme miniaturization, traditional silicon-based semiconductor technology is facing major limitations. As device dimensions shrink to the nanometer scale, challenges such as leakage current, heat dissipation, and …
Published in Journal of Semiconductor Devices and Circuits · Vol. 13, Issue 2, 2026 Read article
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Thin Film Solar Cells: Progress in Materials, Fabrication, and Efficiency Enhancements
Abstract: Thin film solar cells (TFSCs) have drawn a lot of interest because of their potential for efficient and reasonably priced photovoltaic energy conversion. Their flexibility, low weight, and lower material consumption make them a desirable substitute for conventional solar cells made of crystalline silicon. This review explores recent advancements in TFSC technology, with a focus on materials, fabrication techniques, and efficiency improvements.Various thin-film materials, such as amorphous silicon (a-Si), perovskite, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 37–42 Read article
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Enhancements in Titanium Matrix Composites: A Multifaceted Exploration of Various Structural Ceramics Reinforcement
Abstract: This research study delves into the comprehensive exploration of Titanium Matrix Composites (TMCs) reinforced with Silicon Carbide (SiC), Alumina (Al2O3), and Boron Nitride (BN). The investigation is structured into three key phases, each addressing essential aspects of TMCs: Phase 1 involves materials and manufacturing, where TMC coupons were fabricated through the stir casting technique with varying compositions of aluminum and silicon carbide. Phase 2 focuses on characterization and defect detection, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 1, 2024 · pp. 83–94 Read article
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Properties of ZnO Thin Film deposited on Flexible Substrate using RF Sputtering
Abstract: Semiconductor materials demand is increased in recent years, due to new emerging technologies. There is need to find the alternate for silicon in electronics industry, as silicon is brittle in nature and has low efficiency, which makes it unsuitable for transparent and flexible device. Zinc oxide (ZnO) is emerging as popular choice of researchers due to its wide range of properties, abundancy and non-toxicity. This work explores the properties of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 4, 2024 · pp. 50–56 Read article
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A New Developed Photoelectrochemical Cell for Hydrogen Generation
Abstract: There are many methods for the industrial production of hydrogen, including: steam reforming of methane and natural gas; coal gasification; biotechnology; electrolysis of water, etc. The most effective method of obtaining of pure hydrogen is the use of photoelectrochemical cell. Photoelectrochemical cells produces hydrogen directly from solar energy. In a photoelectrochemical cell, a silicon semiconductor with an anode attached to it, immersed in an aqueous electrolyte solution and excited by …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 01–10 Read article
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Theoretical Study of Surface Waves in Hexagonal Boron Nitride (hBN)
Abstract: Hexagonal boron nitride (hBN) is a wide bandgap semiconductor material in which Boron (B) and Nitrogen (N) atoms form hexagonal structure and has number of robust properties of technological importance. Boron nitride nanotubes (BNNTs) are very nice area of research in recent years. Its structure is similar to carbon nanotubes (CNTs) where carbon atoms are arranged in hexagon. hBN is also known as White Graphene. Various methods are employed to …
Published in Research & Reviews : Journal of Physics · Vol. 13, Issue 1, 2024 Read article
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A Comprehensive Review of FinFet Technology: Advantages, Challenges and Applications
Abstract: This has been complemented by improvements on the new layers that have surpassed the manufactures planar transistor by the new FinFET (Fin Field-Effect Transistor), which enhance modern demands on high performance, small size and low power consumption. This review is for a timely information on the latest development on FinFET technology, such as by curbing leakage currents by 50 percent and enhancing its speed by 30 percent proving that FinFETs …
Published in Journal of Semiconductor Devices and Circuits · Vol. 11, Issue 3, 2024 · pp. 1–12 Read article