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75 articles for “Design-Down Approach”
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Neuroimaging in Clinical Trials for Huntington’s Disease: Emerging Research Findings: The Advancement Directions and Implications
Abstract: Neuroimaging is very important in coordinating and conducting Huntington’s disease clinical trials as a tool in selecting patients, managing safety concerns, and assessing the benefits of interventions. This review presents the current uses and potential future uses of structural and functional magnetic resonance imaging (MRI), diffusion imaging, positron emission tomography (PET), proton magnetic resonance spectroscopy (MRS), perfusion imaging, and magneto encephalography (MEG) in HD trials. We describe how these modalities …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 32–44 Read article
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ML Analysis of Factors Affecting Vaccination in Rural Children: A Machine Learning Approach
Abstract: Vaccination remains one of the most effective public health interventions for preventing childhood diseases, yet rural regions in India continue to experience uneven immunization coverage due to multiple socioeconomic and geographic barriers. This research applies machine learning techniques to identify and analyze the major determinants influencing childhood vaccination uptake in rural communities. The study utilizes survey-based demographic, socioeconomic, and healthcare-related parameters to build predictive models that classify children as vaccinated …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 Read article
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Unveiling the Role of Lead Molecules in CADD: A Systematic Review
Abstract: The word "medicate plan" alludes to the objective creation of modern drugs. Arbitrary screening of engineered compounds, engineered of organically dynamic compounds based on actually happening drugs, amalgamation of basic analogs of actually happening lead particles, and usage of the bioisosteric hypothesis are a few of the strategies that have been utilized. As a result, the most recent drift in medicate plan is to either completely enhance a lead or …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Pick and Place Drone using Primus X Flight Controller
Abstract: The development of an uncomplicated drone for pick-and-place tasks makes this project a superb beginner’s hands-on exercise. The drone is outfitted with an accelerometer, gyroscope, magnetometer, and barometric sensors which allows for controlled, stable flight. A Primus X flight controller powers the drone due to these features. The drone is sustained by a battery which drives four geared motor propellers. The gripper is designed in SolidWorks and cut using a …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 4, Issue 1, 2026 Read article
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Study to Assess the Effectiveness of Teaching Program on Knowledge Regarding Management of Patients with Regenerative Orthopedics Procedures Among Orthopedic Nurses at Selected Orthopedic Departments
Abstract: Regenerative therapy is an emerging treatment approach in medical science. It focuses on the use of stem cell therapy, biological treatments, tissue engineering, platelet-rich plasma, prolotherapy, and nutraceutical supplements to replace or restore dysfunctional structures or organs. Regenerative therapy emphasizes the body’s natural healing process; it supports physiological healing mechanisms and repairs damaged tissues. It is a minimally invasive approach with expanding applications across various medical fields, including surgery, degenerative …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 7–11 Read article
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Innovative Approaches in Bioinspired and Biomimetic Membrane Technologies: Bridging Nature and Engineering
Abstract: Bioinspired and biomimetic membranes represent a ground breaking advancement in membrane technology, offering innovative solutions to critical global challenges in water purification, chemical separation, and energy conversion. These membranes leverage the exceptional transport properties of biological systems, particularly through the incorporation of aquaporin proteins, which facilitate rapid and selective water transport. This review synthesises recent developments in aquaporin-based membranes, highlighting their remarkable efficiency in desalination processes, where they serve as …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 53–60 Read article
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A Conceptual Framework for AI-Integrated Metabolomics in Predictive Health Systems for Resource-Constrained Environments
Abstract: The increasing prevalence of non-communicable diseases (NCDs) continues to place a significant strain on healthcare systems, particularly in low- and middle-income regions where access to early diagnostic infrastructure is limited. Conventional healthcare approaches remain largely reactive, often detecting diseases at advanced stages when treatment effectiveness is reduced. This challenge underscores the need for predictive, cost-effective, and data-driven healthcare solutions. This study presents a conceptual framework that integrates metabolomics with artificial …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 2, 2026 Read article
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Beyond Generalized Treatment: The Future is Personalized Medicine
Abstract: Personalized medicine, which is also called as precision medicine, is reestablishing the view of new healthcare by replacing the traditional "one-size-fits-all" approach with individual therapies made according to a patients unique genomic organization, environment, and lifestyle. This article talks about the scientific foundation, important applications, ethical challenges, and the significant potential of personalized medicine in enhancing the clinical outcomes. From oncogenic and genetic disorders to chronic diseases, the addition of …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 Read article
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Physiotherapy’s Impact on an Athlete’s Physical and Mental Well-being: A Review
Abstract: Physiotherapists are essential in helping athletes with physical and psychological issues connected to their activity. Effective treatment and the formulation of athletes' expectations regarding the restoration of health issues require a solid interaction between the physiotherapist and the athlete. Thus, when designing a rehabilitation program, it is imperative to take the expectations of the athletes with the specific problem into consideration. Since the dawn of civilization, physiotherapy methods have been …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 22–28 Read article
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Emerging Trends in Membrane-Based Gas Separation Technologies
Abstract: Membrane technology has emerged as a groundbreaking solution in various fields, revolutionizing industries such as water treatment, energy production, biomedicine, and environmental protection. Over the past few decades, significant advancements have been made in membrane materials, fabrication techniques, and performance optimization. With the growing global demand for efficient and sustainable separation processes, research has increasingly focused on enhancing membrane permeability, selectivity, and durability to improve performance across various industries, including …
Published in International Journal of Membranes · Vol. 2, Issue 1, 2025 · pp. 16–22 Read article
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Diet(Nutrition) Recommender using Machine Learning
Abstract: In an era where maintaining a healthy lifestyle has become a priority, personalized dietary recommendations play a crucial role in guiding individuals towards achieving their nutritional goals. The Diet Recommendation System is an inno- vative application that combines user-specific data with machine learning algorithms to provide tailored dietary suggestions. This system is designed to simplify the process of meal planning and promote healthier eating habits. The Diet Recommendation System is …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
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Optimizing Solo Athletic Excellence: Analyzing Psychological, Economic, and Cultural Drivers in Elite Sports Performance
Abstract: This research paper explores the multifaceted drivers behind elite solo sports performance, integrating psychological, economic, and cultural perspectives to understand how these factors contribute to athletic excellence. The study synthesizes insights from a variety of academic journals, authoritative books in sports science, and articles from prominent sports and psychology magazines. Through a mixed-methods approach, we analyze the resilience and mental strategies employed by solo athletes, assess the economic conditions that …
Published in Recent Trends in Sports · Vol. 1, Issue 1, 2024 · pp. 16–26 Read article
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Library Science Education in India: Evolution, Emerging Trends, and Challenges
Abstract: Library and Information Science (LIS) education in India has undergone significant transformation over the past century, evolving from traditional library training to a dynamic academic discipline shaped by technological advancements and changing information needs. This study examines the origin, development, and current status of LIS education in India, with particular emphasis on its evolution in the contemporary digital environment. The research adopts a qualitative and exploratory approach and is based …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 75–87 Read article
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Ethical Risks of Generative AI in Education: Challenges, Implications, and a Responsible Use Framework
Abstract: The rapid diffusion of generative artificial intelligence (AI) technologies in educational settings is reshaping how teaching, learning, and assessment are designed and enacted. Large language models and related generative systems offer powerful capabilities for content creation, personalized feedback, and instructional support, promising gains in efficiency and learner engagement. However, their growing use also introduces a complex set of ethical risks that challenge foundational educational values such as integrity, equity, transparency, …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 23–30 Read article
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Effectiveness of Spencer Technique of Mobilization on Adhesive Capsulitis: A Single Case Study
Abstract: Background: Frozen shoulder, or adhesive capsulitis, is a condition characterized by pain, restricted motion, and stiffness in the shoulder joint. This occurs due to inflammation and the thickening of the joint capsule. The Spencer technique, is a manual therapy method consisting of seven steps designed to improve shoulder function by enhancing joint mobility, circulation, and lymphatic flow. These movements target shoulder extension, flexion, circumduction, abduction, and adduction, to reduce stiffness …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 14–20 Read article