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166 articles for “ADME analysis”
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Review paper on concrete mix design optimization using machine learning based algorithm
Abstract: Concrete is an essential part of most construction works in civil engineering. The mix design of concrete is usually specified in terms of prescription or performance-based approach. One of the most important procedures is proportioning the concrete mix, which requires taking several safety precautions to get the proper amounts of elements like cement, aggregate, water, and admixtures. The current study offers a thorough analysis of the Artificial Neural Networks (ANN) …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 311–320 Read article
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The Social Media Misinformation Loop: An Analysis of Consumption and Sharing Behaviours among Medical Students
Abstract: Background: The contemporary information landscape is largely dominated by social media, which has emerged as a major source of information for medical students. This study aims to investigate the information consumption and sharing behaviours of medical students in Jammu and Kashmir, India, in the context of misinformation and its growing influence. Methods: A cross-sectional survey using a structured questionnaire was administered to 668 students from 13 medical colleges. The data …
Published in Research and Reviews: A Journal of Health Professions · Vol. 16, Issue 1, 2026 Read article
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Targeting PTPN22 in Arthritis: Molecular Docking and Pharmacokinetic Evaluation of Artemisia vestita Compounds
Abstract: Rheumatoid arthritis (RA) is a long-term autoimmune condition characterized by inflammation of the synovial membrane, commonly resulting in swelling, pain, stiffness, and overall fatigue. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) has been identified as a risk factor linked to various autoimmune diseases, including RA. In the PTPN22 gene, two missense Single nucleotide polymorphisms (SNPs) are associated with autoimmune conditions. The R620W (C1858T, rs247660) variant in exon 14 has been …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 20–31 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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Formulation and development of Lamivudine Nanoemulsion by using Emulsifying Polymers and It’s Evaluation
Abstract: Nanoemulsion is a novel approach to medicine delivery that helps to increase the bioavailability of drugs that aren’t particularly soluble in water. In this research work, nanoemulsion of Lamivudine was formulated by using polymers such as SPAN 80, TWEEN 80 and Whey protein concentrate with the help of Ultrasonication technology. The formulation was optimized. It was evaluated by assessing pH, viscosity, turbidity, in vitro franz diffusion study, particle size distribution, …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 22–35 Read article
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Histological Effects of Nano-Synthesized Particles of Nagilla Sativa Seeds Extract on Digestive System of Male Albino Mice
Abstract: This revision considers the belongings of Tartrazine and black seed nanoparticles on body mass and cardiac histology in male albino mice. Group of male mice were separated into 4 clusters: a regulator cluster getting physiological saline, other cluster preserved with Tartrazine (20 mg/kg), another cluster getting equally Tartrazine with N. sativa nanoparticles (100 mg/kg), while last cluster preserved solely besides to N. sativa nanoparticles (100 mg/kg). The assumptions confirmed an …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 1–6 Read article
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Emerging Therapies for Diabetes Mellitus: Efficacy and Safety of USFDA-Approved Drugs and Late-Stage Clinical Trials
Abstract: This review provides a comprehensive analysis of drugs approved by the U.S. Food and Drug Administration (USFDA) for managing diabetes mellitus (DM) from 2013 to 2022, including emerging treatments from phase 3 clinical trials during this period. Over the past decade, the treatment landscape for diabetes has evolved significantly, with new therapies not only improving blood sugar control but also targeting broader health outcomes like heart and kidney health. In …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 11–23 Read article
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Evaluation of Patient-Specific Quality Assurance for RapidArc Treatment Delivery Using Dose Volume Histogram
Abstract: This study aims to evaluate the application of dose volume histogram (DVH) metrics within the patient-specific quality assurance (PSQA) protocol in various sites for RapidArc treatment delivery. Forty patients were included in this study, of which twenty each Head and Neck (H&N) and Pelvis Rapid Arc plans were evaluated. Octavius 4D 1500 detector array with vented parallel plate ion chambers was used for this study, which reconstruct the pre-treatment measured …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 14–22 Read article
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Remote Monitoring Sensor Systems and Applications in Health Informatics: Fostering Shell Programming
Abstract: The fascination of sensor systems has been promising for health informatics as their direct initiative for real-time information by observing its accuracy that was required at the time for data collection, monitoring and analysis to improve patient well-being and health system administering. By integrating these systems with wearable devices, biomedical sensors, and other IoT-enabled technologies, patients can experience continuous health tracking, early disease detection, and remote patient monitoring. For example, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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A study on Public Perception and self-medication practices with Over-the-counter (OTC) Drugs
Abstract: Over-the-counter (OTC) medications are commonly used by individuals for self-medication due to their easy availability and the general belief that they are safe. However, misuse can lead to negative health outcomes such as adverse reactions, drug interactions, and delays in seeking professional medical care. In a country like India, where enforcement of drug regulations can vary and socioeconomic factors play a major role, the practice of self-medication is especially widespread. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 01–07 Read article
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In silico analysis of Abrus precatorius L. as a potential agonist of PPARγ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to life-threatening complications such as, kidney damage, heart disease and vision impairment. It can also weaken the immune system, making patients more prone to infection. Although treatments …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Relationship between Socio-Economic Status and New Word Learning
Abstract: New word learning refers to the process of learning of novel words which are not in the vocabulary of the person and it varies as a function of many potent variables. Socio economic status is one of the major variables believed to have a significant effect on new word learning. The aim of the current study to investigate if new word learning varies as a function of socio-economic status. 74 …
Published in International Journal of Education Sciences · Vol. 1, Issue 2, 2024 · pp. 19–24 Read article
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**Innovation and Quality Assurance in School Management: A Research Study on Indian Schools in the Context of NEP 2020**
Abstract: The quality of school education is strongly influenced by the efficiency and vision of school management practices. In today’s rapidly changing educational landscape, schools are expected to perform responsibilities that extend beyond routine administration. They must ensure academic excellence, learner well-being, value- based education, inclusion, transparency, and accountability to parents and society. However, many schools still function through traditional management patterns that focus mainly on record-keeping, examination routines, and compliance …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 16, Issue 1, 2026 Read article
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Materials, Mechanism and Mechanical Properties of Self-curing Concrete: A Review
Abstract: Concrete, a key construction material with high demand for infrastructure development, necessitates an increased water input both during production and curing. This poses a challenge in areas facing acute water scarcity, highlighting the importance of research to reduce water consumption in the process. The process of hydration of the cement within concrete, without outside source, such as water for curing is referred to self curing. Improper curing will cause self …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 185–194 Read article
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Consumer Awareness and Adoption Barriers of E-Pharmacy Services in Delhi/NCR: A Mixed-Methods Investigation
Abstract: Background: The rapid digitization of India's pharmaceutical market has positioned e-pharmacies as a transformative force; yet, consumer adoption remains significantly low despite growing awareness. Objectives: This study investigates consumer awareness levels, purchasing behaviors, trust perceptions, and adoption barriers regarding e-pharmacy services among urban Indian consumers. Methods: A sequential explanatory mixed-methods design was employed. Quantitative data were gathered via a structured questionnaire administered to 65 respondents in Delhi. Qualitative insights were …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Regulations for Toothbrushes: A Comparative Study Between India, the US, Europe, and Australia
Abstract: Toothbrushes are essential tools for maintaining oral hygiene, making their regulation vital for consumer safety and health efficacy. This article presents a comparative analysis of toothbrush regulations in India, the United States, Europe, and Australia, highlighting the unique frameworks each region has developed to address manufacturing, distribution, and marketing challenges. In India, the Bureau of Indian Standards (BIS) and the Food Safety and Standards Authority of India (FSSAI) set safety …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 1–6 Read article
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An Overview of Smart Attendance System and Communication system
Abstract: Our attendance is made more sophisticated and self-controlled by using "the smart attendance system (SAS)," which is the topic of this paper. It has an innovative QR scanner technology that makes the process accurate and simple. The system operates efficiently, saving us time and requiring less labor to maintain attendance. Previous versions of the monitoring system had problems locating students and required a tedious manual attendance method. Thanks to developments …
Published in International Journal of Radio Frequency Innovations · Vol. 1, Issue 2, 2023 · pp. 12–17 Read article
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Expanding Hicks Contraction Theory, Multi-Valued Mappings in Generalized b-Menger Spaces
Abstract: This paper extends the Hicks contraction theory to multi-valued mappings within generalized b-Manger spaces, a class of metric-like structures that accommodate more flexible distance functions. By introducing new definitions, such as generalized admissibility conditions and weak compatibility in the multivalued sense, we provide a comprehensive analysis of how these contractions behave in broader topological and metric contexts. Our approach systematically generalizes classical contraction principles by relaxing conventional constraints, thereby broadening …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 1, 2025 · pp. 1–05 Read article
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Assessment of the Efficacy of Demonstration Techniques in Enhancing ASHAs’ Knowledge and Practice of First Aid Management for Dog Bites and Minor Injuries in Rural Bhopal
Abstract: Background: The individuals administering first aid, commonly referred to as first aiders, assume responsibility for the entire situation, including the injured individual and the nature of the injury or illness. They possess the understanding of what actions to avoid, in addition to what actions to take, thus preventing common errors often made by untrained individuals despite good intentions. Furthermore, they recognize that their knowledge and proficiency in first aid can …
Published in International Journal of Community Health Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 29–46 Read article
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A MERN-Based Crime Management System: Enhancing Crime Reporting and Law Enforcement Collaboration
Abstract: In the modern digital age, efficient crime management is essential for safeguarding the public and upholding law and order. This project introduces the development of a Crime Management System (CMS) built with the MERN stack (MongoDB, Express.js, React, Node.js) to streamline crime reporting, monitoring, and coordination among law enforcement agencies. The CMS is designed to streamline the processes of crime reporting, record management, and data analysis, addressing inefficiencies in traditional …
Published in Journal of Advanced Database Management & Systems · Vol. 12, Issue 3, 2025 · pp. 40–52 Read article