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337 articles for “severity”
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Unmasking Human Metapneumovirus: The Emerging Threat to Vulnerable Populations
Abstract: Human Metapneumovirus (HMPV) is a contagious respiratory virus that commonly spreads among individuals. It can cause serious infections, especially in high-risk groups like infants, older adults, and individuals with weakened immune systems.It is a major contributor to acute respiratory illnesses. Since its discovery in 2001, HMPV has been identified as a common cause of both upper and lower respiratory tract illnesses, with clinical presentations ranging from mild symptoms to severe …
Published in International Journal of Virus Studies · Vol. 2, Issue 1, 2025 · pp. 16–24 Read article
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A Study on Security Requirements of IOT
Abstract: In terms of speed, internet technologies have surpassed traditional technologies. Although the Internet's explosive growth has allowed it to reach its full potential, there are several security dangers associated with it. Many consumer-grade IoT devices are not designed with robust authentication protocols, making them easy targets for hackers. To address this, stronger multi-factor authentication (MFA) methods and certificate-based authentication should be implemented to ensure that only legitimate devices gain access …
Published in International Journal of Radio Frequency Innovations · Vol. 3, Issue 1, 2025 · pp. 24–28 Read article
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COVID-19 Resurgence in 2025: India’s Continuing Public Health Challenge
Abstract: The year 2025 has witnessed the resurgence of COVID-19, reigniting concerns at both global and national levels regarding the persistent threat posed by SARS-CoV-2. In early 2025, India witnessed a moderate resurgence of COVID‑19, characterized by the emergence of Omicron sub-variants and a rise in mild-to-moderate infections. As of mid-June, active COVID‑19 cases in India totaled approximately 6,000–7,400, with hotspots in Kerala (~2,100 cases), Delhi (~600), Maharashtra (~500), and several …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 2, 2025 · pp. 16–23 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Rodents and Zoonotic Diseases: Environmental Drivers and Prevention Measures
Abstract: Among the most ubiquitous animal species, rats spread several human diseases. Found in cities, rural areas, and everywhere in between, rats have adapted remarkably well to living alongside people. Unfortunately, this close contact makes it easier for them to carry and pass on harmful germs. Their biology, fast breeding, and ability to host various bacteria, viruses, and parasites often without getting sick themselves make them especially effective at spreading disease.This …
Published in International Journal of Virus Studies · Vol. 2, Issue 2, 2025 · pp. 12–21 Read article
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Studying the effects of Exposure to Chemicals on The brain and Nervous System and The risk of Chemical Pollution
Abstract: Scientific research and studies on chemical pollution show that exposure of the brain and nervous system to chemicals causes serious damage ranging from cognitive, motor, and nerve cell disorders to chronic diseases such as Alzheimer's and neurological paralysis. These substances (such as lead ions, mercury, solvents that combine and dissolve easily in the blood, and pesticides) disrupt neurotransmitters and cause cell damage, especially during the early stages of body development. …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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A Note on Vaccine Design Using Bioinformatics Methods and Applications
Abstract: Vaccines prevent infectious diseases caused by viruses and bacteria saving millions of lives.It consists of certain agents that resemble disease causative agentsand stimulates our immune system to recognize and fight foreign antigens. Immune function or an immune response is the fundamental basis of the vaccine's mechanism. Vaccines are pharmaceutical derivatives that provide an affordable way to prevent diseases.Various bioinformatics approaches can be incorporated into vaccine design studies and development. Reverse …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 1, 2023 · pp. 1–9 Read article
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Study of Cost Overrun in Repair & Rehabilitation Projects in India
Abstract: In broad sense, the word "rehabilitation" suggested putting a building back to how it was before. The specialized area of repair and rehabilitation engineering necessitates knowledge and skills that go beyond those needed for design and construction engineering. Repair and rehabilitation projects are significantly more challenging and more complicated than new construction projects. It is vital to take a methodical approach to structural deterioration, and technology management and economics should …
Published in International Journal of Architectural Design and Planning Read article
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Exploring The Multitarget Pharmacological Mechanism of Diabex for T2dm by Combining Network Pharmacology and Molecular Docking Techniques
Abstract: Objective: Hyperglycemia brought on by an absolute or relative absence of insulin synthesis or action characterises a set of illnesses known as diabetes mellitus. Chronic hyperglycemia in diabetes mellitus has been linked to organ damage, heart, and blood vessels. The persistent metabolic condition Diabetes is a severe global issue with negative social, health, and economic effects. It is a type of metabolism disorder that interferes with food digestion in the …
Published in International Journal of Bioinformatics and Computational Biology Read article
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To Propose an Effective Process for Refurbishment Projects: through BIM
Abstract: Building refurbishments include enhancing, upgrading, renovating, retrofitting, and repairing existing structures. The construction sector considers it to be an important component. Building refurbishment projects are known for their high degree of complexity and uncertainty, which frequently incorporates elements like design changes and inadequate or unavailable information that may lead to various issues. Issues related to different stages of refurbishment projects were identified through literature and case studies. According to the …
Published in International Journal of Architectural Design and Planning Read article
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In Silico Prediction of Multitarget Mechanism of Quinoline and Its Analogs on Phosphoinositide-3-Kinase Pathway Proteins
Abstract: Objective: Phosphoinositide 3-kinases (PI3Ks), the target of rapamycin (PI3K/Akt/mTOR, PAM), are a family of enzymes that play a role in the growth, proliferation, differentiation, motility, survival, and intracellular trafficking of cells, all of which are essential for healthy cellular function and are also connected to cancer. In this study, quinoline and its derivatives were employed to analyze its inhibition activity on the phosphoinositide-3-kinase pathway. Methods: In this work, eight phytocompounds …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 57–76 Read article
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Assessment of the Physical Environment of Child Care Institutions
Abstract: The environment in which orphans live is considered a vulnerability by several international organizations that refer to parentless children as “at risk.” A child care facility accommodates these distressed children who lack parental care, by providing a safe protective environment that contributes to the well-being of the child as well as providing a nurturing environment for their development. All resident children within institutional care have to share not only the …
Published in International Journal of Architectural Design and Planning Read article
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Enhancing the Strength of Black Cotton Soil with Enzyme and Industrial Waste
Abstract: Expansive soils are troublesome and prone to ground movements, which can cause substantial damage to underlying buildings as well as a loss in bearing capacity. Moisture fluctuation activates the expansive character of soils, causing it to swell and shrink. This has long been known in geotechnical engineering. To treat expansive soils, a variety of stabilizing additives such as lime, cement, and fly ash have been employed. In recent years the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 1–11 Read article
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Uses of Organic Fabrics in Home Interiors
Abstract: This paper explores the uses of organic fabrics in home interiors. Organic fabrics are gaining popularity in the field of interior design as more people become aware of the harmful effects that conventional fabrics have on the environment. These fabrics offer several benefits, including sustainability and durability making them a popular choice for interior designers. Organic fabrics can be used in various ways in home interiors, from bedding and curtains …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 1–16 Read article
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Biophilic Design in Healthcare Centre
Abstract: The human affinity towards nature is innately genetic and has a strong correlation with human well- being. This innate affiliation towards nature has been coined as Biophilia which focuses on the growing need for human interaction with nature, nature-like elements, and the natural environment in and around the built form for improving human well-being. Biophilic design can also provide physical opportunities offered through its design considerations in the realization of …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 31–50 Read article
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Energy performance analysis: An exploratory study of HVAC systems in efficient management of data centres
Abstract: Data center growth is being driven by the rapid proliferation of cloud services. Data centers are using an increasing amount of energy. The network is severely impacted by server workloads, cooling, and supporting equipment. The study aims to identify the energy consumption involved in building services and their operations and analyze the ways in efficient management of performance in data center. The objective of the study is to identify the …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 2, 2023 · pp. 51–71 Read article
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Matching Minutiae Fingerprint Q-Learning Approach for Detail Coordination: Identifiable Mark Point
Abstract: The use of fingerprints for high-precision recognition and identification of people is one of the most reliable biometric symbols because it is non-invasive. In this paper, we propose an innovative approach to detect details on low contrast resolution image quality of fingerprint images. Existing algorithms are not very susceptible to sound and image excellence due to the lack of level of intensity. We recommend a reliable route to find fingerprints …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 1, 2023 · pp. 1–15 Read article
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Predicting and Prohibiting the Risk of Heart Failure Using Machine Learning
Abstract: It is challenging to estimate the likelihood of complex chronic disease while treating conditions like heart failure. The application of machine learning, an area of artificial intelligence, in cardiovascular care is growing quickly. In essence, it defines how computers classify and understand data, or choose a task with or without human intervention. The theoretical underpinnings of machine learning are models that accept input data (such as images or text) and …
Published in International Journal of Computer Science Languages · Vol. 1, Issue 1, 2023 · pp. 15–20 Read article
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A Comparative Study on Associated Factors of Hypertension Among Working Women and Non-working Women
Abstract: Background: One in four people worldwide is affected by high blood pressure, which is also the third leading cause of illness and a significant risk factor for death. Compared to non-working women, employed women had a higher prevalence of hypertension. This might be attributed to various factors such as job-related stress, lack of relaxation, and lack of physical activity. Method: Quantitative approach was adopted. To investigate the related determinants of …
Published in International Journal of Women's Health Nursing And Practices · Vol. 1, Issue 1, 2023 · pp. 09–14 Read article