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71 articles for “renal disease”
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Nt-Probnp and Nitrogen Species Measurement As Useful Biomarkers for Detection of Asymptomatic Heart Failure in Patients with Type 2 Diabetes
Abstract: Insidious heart failure is associated or complicated hypertension, coronary artery disease, diabetes, chronic lung disease, atrial fibrillation, renal failure, depression, and anemia. High plasma NT-proBNP level found to be a predictive value in detecting latent left ventricular diastolic dysfunction. The aim of the study is to detect asymptomatic heart failure in outpatient type 2 diabetic patients using plasma NT-proBNP as a diagnostic biomarker of heart failure and nitrogen species as …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 1, 2015 · pp. 8–12 Read article
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Clinical metabolomics: Useful insights, perspectives, and challenges.
Abstract: Metabolomics provides a comprehensive snapshot of smallmolecule intermediates and end products of cellular processes and thereby links genotype, environment, and phenotype in human disease . Over the last decade, advances in liquid chromatography–mass spectrometry (LC–MS) and nuclear magnetic resonance (NMR) spectroscopy have enabled high-throughput profiling of thousands of metabolites from microliter volumes of clinical samples . Clinical metabolomics is now emerging as a tool for disease diagnosis, risk prediction, therapeutic …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 29–37 Read article
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Assessment of Comorbid Illness Among Patients with Chronic Kidney Disease at Selected Hospitals in Madurai
Abstract: Chronic kidney disease (CKD) is a comprehensive term encompassing kidney damage or a sustained reduction in the glomerular filtration rate over a period of three months or longer. CKD is linked to a diminished quality of life, heightened healthcare costs, and premature mortality. The main objective of this study was to identify the comorbid illnesses among the patient with chronic kidney disease and to associate the comorbid illness with their …
Published in Journal of Nursing Science & Practice · Vol. 13, Issue 2, 2023 · pp. 8–13 Read article
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A Compilation of Case Reports from Ayush Wellness Clinic, President’s Estate, New Delhi, India
Abstract: AYUSH Wellness Clinic was established in the President’s Estate on July 25, 2015 with a view to ensure the accessibility and availability of AYUSH health care services to all officials of President’s Secretariat and residents of President’s Estate. The clinic established with the assistance of Ministry of AYUSH, has OPD level treatment facilities of all the streams of AYUSH (i.e., Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homeopathy). The current …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 7, Issue 1, 2018 · pp. 14–26 Read article
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A Review on Pierson Syndrome
Abstract: Pierson syndrome, also known as microcoria-congenital nephrosis syndrome, is a rare illness that mostly affects the kidney and eye. In 1963, Pierson et al. published the first description of this illness. A genetic mutation in the LAMB2 gene causes this disorder, which is responsible for producing the laminin-2 chain. The retina, neuromuscular junctions, glomerular and ocular basement membranes, and this laminin subunit are all significant components. Congenital nephrotic syndrome is …
Published in Research and Reviews: A Journal of Toxicology · Vol. 13, Issue 1, 2023 · pp. 10–14 Read article
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Assessment of Finerenone Safety and Efficacy in Individuals with Type 2 Diabetes and Chronic Kidney Disease
Abstract: Background: In this work, we provide strong evidence for the safety and efficacy of finerenone in people with type 2 diabetes and chronic kidney disease. Our goal is to improve patients' quality of life and general well-being through our research. Aim: Finerenone exhibited a significant decrease in the likelihood of renal and cardiovascular (CV) events in individuals with both type 2 diabetes and chronic kidney disease. This exploratory subgroup analysis …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 06–09 Read article
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Associations of C-RP with Renal Function Group and some Clinical Parameters in Patients with Dialysis in Iraq
Abstract: Introduction: Chronic kidney disease is a disease for which there are high mortality rates among those infected with many complications, including high rates of inflammation, anaemia, osteoporosis, and other complications. Methods: The current study was designed to evaluate the kidney functions of patients undergoing dialysis, where levels were evaluated Urea, Uric Acid, and Creatinine, in addition to C-Reactive Protein as a progressive of inflammation parameter, and to evaluate anaemia levels …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 4, Issue 1, 2026 Read article
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Yoga: A Cost Effective Lifestyle Method to Control Blood Pressure
Abstract: Hypertension has become a major health concern as it is the predominant risk factor and treated for stroke, coronary heart disease (CHD), heart failure, arterial aneurysms and renal failure. As drug therapy alone is a costly affair for a developing country like India, a need for less experience, nonpharmacological alternative methods should also be taken into consideration. Medication and yoga are some alternative Indian techniques’ which can be used in …
Published in Research and Reviews: A Journal of Health Professions · Vol. 6, Issue 2, 2016 · pp. 31–32 Read article
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Exploring the Pathophysiology of Henoch-Schönlein Purpura (HSP): A Comprehensive Review
Abstract: Blood from tiny veins can leak into nearby tissues, causing purpura, a disorder marked by red spots or patches on the skin that may have an impact on the kidneys. Henoch-Schönlein purpura (HSP) is associated with vasculitis and inflammation of blood vessels. The range of renal conditions associated with purpura includes severe glomerulonephritis and mild proteinuria. For instance, immunological complex accumulation in the renal glomeruli of HSP patients might result …
Published in International Journal of Cell Biology and Cellular Functions Read article
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The Quiet Intruder: An Insidious Presentation of Primary Plasma Cell Leukemia and a Literature Review on Current Treatment Strategies
Abstract: Introduction: Primary plasma cell leukemia (pPCL) is a rare and aggressive plasma cell dyscrasia, defined by ≥5% circulating plasma cells, with poor prognosis and rapid progression. Case Presentation: A 66-year-old African–American female with no prior medical history presented with one week of fatigue, dehydration, and polydipsia. Laboratory evaluation revealed leukocytosis, severe thrombocytopenia, acute kidney injury (creatinine 4.03 mg/dL), and hypercalcemia (13.0 mg/dL) with suppressed PTH. Imaging showed intra-abdominal lymphadenopathy without …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 2, 2026 · pp. 1–5 Read article
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Integration of Biomarkers in III and IV CKD Patients for Evaluation of Their Predictive Value for CVD in CKD Patients
Abstract: Background: Chronic kidney disease (CKD) is presently characterized by the presence of proteinuria and/or a diagnosis of renal impairment. The worldwide significance of CKD is underscored by the fact that its prevalence and incidence have doubled over the past three decades. This paper provides an overview of the existing evidence regarding biomarkers in individuals with CVD or CKD, with a particular focus on the emerging biomarkers (i.e., eGFR, sALB, UACR, …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 3, 2025 · pp. 1–12 Read article
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Computational Identification of Antigenic Proteins and Epitopes in Hantavirus sp. for Drug Repurposing
Abstract: Hantavirus is an emerging virus that spreads from animals to humans and can cause serious illnesses like hantavirus pulmonary syndrome (HPS) and hemorrhagic fever with renal syndrome (HFRS). there are no FDA-approved treatments available for these diseases. This study explores in-silico drug repurposing as a strategy to identify potential therapeutic candidates. The physicochemical, secondary structure, antigenicity, and post-translational modification analysis of hantavirus proteins – specifically the glycoprotein precursor, N protein, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 20–26 Read article
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Clinical and Etiological Profile of Heart Failure Patients
Abstract: This study was undertaken to study the clinical and etiological profile of patients with heart failure at Mamata General Hospital, Khammam. This is a study of clinical and etiological profile of heart failure in patients of above 15 years of age, who were admitted in Mamata Medical College during the period December 2012 to November 2013. The incidence of heart failure (HF) in Mamata General Hospital is less compared to …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 1, 2014 · pp. 6–11 Read article
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Protective Role of Sulforaphane against Multiorgan Toxicity in Rats: An In-vivo and In-vitro Review Study
Abstract: Sulforaphane [1-isothiocyanate-(4R) -(methylsulfinyl) butane] is a natural dietary isothiocyanate produced by the enzymatic accomplishment of the myrosinase on glucopharanin, a 4-methylsulfinylbutyl glucosinolate contained in cruciferous vegetables such as broccoli, brussel sprouts, and cabbage. Exploring of this compound against various oxidative degenerative diseases such as hepatic, nephro and cardiac diseases is growing because of its anticarcinogenic and cytoprotective properties. In several invivo and invitro experimental paradigms proved SFN and its compounds …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 1, 2018 · pp. 1–8 Read article
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An Insight to Hyponatremia in Cirrhosis: Pathophysiology and Management Approaches
Abstract: Cirrhosis is considered by systemic and splanchnic vasodilation that principals to extreme nonosmotic excretion of vasopressin. Hyponatremia is a mutual electrolyte irregularity in progressive liver disease that outcomes from the diminished capability of the kidney to excrete solute-free water that principals to “dilutional” hyponatremia water retention uneven to the retaining of sodium. Hyponatremia is mutual in cirrhosis. It frequently happens in a progressive phase of the disease and is related …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 3, 2020 · pp. 30–46 Read article
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Infection and Viral Pathogenesis of SARS-CoV-2: A Review
Abstract: COVID-19 is a highly infectious disease, posing a massive challenge to global health, with non-specific symptoms, the disease presentation can range from no symptoms (asymptomatic) to severe pneumonia and acute respiratory distress syndrome (ARDS). This review summarizes the current evidence on the major adverse pathological outcomes of COVID-19, which were found to affect different body systems like the respiratory system, cardiovascularsystem, and neurologicalsystem, as well asimpaired hepatic and renal function. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 2, 2022 · pp. 17–23 Read article
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Chronic Kidney Disease: An Overview
Abstract: The key purpose of this review article is to throw light on chronic kidney disease (CKD). Each day people are diagonised with CKD making the need of proper awareness regarding CKD, one of the top public health priorities. Taking this into consideration, the review article outlines some new insight on identification of CKD, classifying it into several stages based on glomerular filtration rate (GFR)/chronic renal failure (CRF) value to be …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 6–9 Read article
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DRUG INDUCED IMMUNE MEDIATED NEPHRITIS: MOLECULAR MECHANISM , PATHWAYS AND CLINICAL IMPLICATIONS
Abstract: Drug-induced immune-mediated nephritis (DI-IMN) has become a more widely known cause of acute kidney injury (AKI), with the potential for development to chronic kidney disease if not detected and treated promptly. T-cell hypersensitivity to pharmaceuticals, such as antibiotics, proton pump inhibitors, nonsteroidal anti-inflammatory drugs, and immunological drugs, are the major causes for it. Beyond clinical burden, DI-IMN reflectsintricate molecular interactions that sustain interstitial inflammation and tubular injury. These interactions include …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 13–29 Read article
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The Function of Diuretics in Current Medical Practice and Prospective Advancements
Abstract: Diuretics have a rich history that spans several centuries, and this review aims to highlight their progression and clinical uses. We start by exploring kidney physiology, followed by a description of how diuretics function through symporters in the renal tubules. Different categories of diuretics are outlined, along with details of their specific actions. Next, we investigate the clinical use of diuretics in conditions, such as congestive heart failure and hypertension, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 70–75 Read article
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A Study and Report on Impact of Clinical Pharmacy Services Over Indian Health Care System in the Management of Chronic Disorders/Diseases in Hospital
Abstract: The study aims to ensure safe, effective, economic, and patient friendly with the knowledge inputs of each professional practice. With the primary and secondary objectives being: to study the role of the clinical pharmacist/doctor of pharmacy professional in the management of chronic diseases/illness, minimise medication/prescription errors, minimise/prevent adverse drug reactions, all types of drug interactions, and unnecessary healthcare costs, reducing drug-related problems and to monitor drug therapy efficiently, attain desired …
Published in Research and Reviews: A Journal of Health Professions · Vol. 11, Issue 2, 2021 · pp. 46–82 Read article