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1222 articles for “design and development”
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Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
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Next-Generation mRNA Vaccines: Applications Beyond COVID-19
Abstract: Messenger RNA (mRNA) vaccine technology has become a paradigm shift in contemporary medicine and, with remarkable success in the COVID-19 pandemic, has opened the door to a new wave of vaccines development. In contrast to the traditional vaccine methods, mRNA vaccines are based on the synthetic genetic code that allows host cells to express target antigens, thus eliciting strong humoral and cellular immunity. The speed of development, efficacy, scalability of …
Published in International Journal of Vaccines · Vol. 3, Issue 2, 2026 · pp. 15–26 Read article
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Embracing Health, Safety, and a Greener Environment in the Construction of Offshore Structures
Abstract: Offshore infrastructure (oil and gas platforms, offshore wind farms, subsea cables, ports, and associated works) plays a vital role in energy, communications, and trade. However, construction activities offshore create complex safety, public health and environmental risks from worker injuries and exposure to hazardous substances, to marine pollution and ecosystem damage with downstream human health effects. This paper reviews the hazards, regulatory and management frameworks, lessons from major incidents, and practical …
Published in Journal of Offshore Structure and Technology · Vol. 12, Issue 3, 2025 · pp. 30–41 Read article
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AI-Powered Drug Delivery: Revolutionizing Formulation Science
Abstract: Artificial Intelligence (AI) is emerging as a groundbreaking tool in revolutionizing Drug Delivery Systems (DDS), offering promising advancements in precision, efficiency, and personalized treatment strategies. The integration of AI technologies into pharmaceutical research and development is transforming how drugs are formulated, delivered, and monitored in real time. By leveraging machine learning algorithms and data analytics, researchers can design drug delivery models that are not only more effective but also tailored …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 48–61 Read article
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Generative AI-Based Inverse Design of Sustainable Biodegradable Polymers with Target Mechanical and Thermal Properties
Abstract: The escalating global plastic pollution crisis has intensified the urgent need for sustainable biodegradable polymer alternatives that can match or exceed the performance of conventional petroleum-based plastics while minimizing environmental impact. However, traditional polymer discovery approaches are severely constrained by high experimental costs, protracted development cycles spanning years, and fundamental inability to simultaneously optimize multiple conflicting material properties such as mechanical strength, thermal stability, and degradation kinetics. This study presents …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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AI-driven Flood Surveillance and Dam Control: Advancing Resilience Through Data Science
Abstract: This study presents the development and real-world deployment of an intelligent system for flood monitoring and automated dam gate control using artificial intelligence (AI) and internet of things (IoT) sensors. Supervised machine learning models are developed to predict floods up to 48 h in advance. An automated dam gate operation system is designed to leverage the flood forecasts and real-time stream water levels for emergency control. The complete end-to-end infrastructure …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 2, 2023 · pp. 9–17 Read article
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TensorFlow: Architecture, Applications, and Future Challenges
Abstract: TensorFlow, an open-source machine learning platform created by Google, has revolutionized how artificial intelligence (AI) systems are built and implemented. Designed to support scalable and flexible model training across CPUs, GPUs, and TPUs, TensorFlow enables researchers and developers to construct advanced deep learning models with efficiency and precision. This study provides an in-depth examination of TensorFlow's architecture, including its use of dataflow graphs and tensor-based computation. We explore its adaptability …
Published in Journal of Open Source Developments · Vol. 12, Issue 2, 2025 · pp. 41–50 Read article
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Optimization of Lightweight Polymer Composites Using Finite Element Analysis Machine Learning and Topology Optimization Techniques for Aerospace Applications
Abstract: The advancement of aerospace engineering depends on lightweight polymer matrix composites (PMCs) because they help decrease weight while improving fuel efficiency and payload capacity together with increased structural integrity. Research developed a computer program comprising FEA with ANN and TO optimize high-performance PMCs through integrated design approaches. The combination of Python-controlled LS-DYNA simulations measured hybrid composite laminate resistance to impact while an ANN model obtained data from simulations to forecast …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 693–709 Read article
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Optimization of a new Bebq2/BCP-based OLED structure for optimum performance
Abstract: Opto-electronic devices exhibit highly nonlinear current–voltage (I–V) characteristics that significantly affect charge injection, transport, and recombination, evaluating their performance remains a difficult challenge. Device optimization is a key research goal in organic light-emitting diodes (OLEDs), as the thickness and arrangement of individual functional layers greatly influence electrical and optical responses. For a suggested Bebq2/BCP-based OLED structure, this work methodically examines the movement of charge carriers, their transport behavior, and the …
Published in Journal of Semiconductor Devices and Circuits · Vol. 13, Issue 2, 2026 Read article
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A Threshold-Weighted Mathematical Fusion Model for Epidemic Outbreak Prediction Using SEIR Residual Dynamics and Cloud-Based Machine Learning
Abstract: Accurate prediction of epidemic outbreaks is critical for effective public health management, resource planning, early warning generation, and timely intervention by municipal authorities. Traditional compartmental models such as Susceptible–Exposed–Infectious–Recovered (SEIR) offer valuable epidemiological insights and mathematical interpretability; however, they may not adequately capture the complex nonlinear relationships present in real-world urban health systems. Conversely, data-driven machine learning techniques can identify hidden patterns in large datasets but often lack epidemiological structure …
Published in Research & Reviews : Journal of Statistics · Vol. 15, Issue 2, 2026 · pp. 12–19 Read article
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The Impact of Robot-Assisted Care on Cognitive Health and Mental Well-Being of the Elderly
Abstract: The rapid advancement of robotics and artificial intelligence (AI) has led to the development of robot-assisted care technologies, which are increasingly being deployed in elderly care settings. These robots are designed to provide physical assistance, emotional support, and cognitive stimulation for older adults. As the global population of elderly individuals grows, particularly in aging societies, it becomes increasingly important to explore innovative solutions that enhance the quality of life and …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 3, Issue 1, 2025 · pp. 1–6 Read article
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Rapid Forecasting of Short-run Electric Power Demand Profiles of India Using the Statistical Method of Z Scores
Abstract: Power demand profile prediction for a region or nation is a critical part of the energy system design and operational planning process. A simplified method based on non-dimensionalizing power demand data from previous years using Z scores calculated from the mean and standard deviation of the profiles is developed in this study to forecast monthly demand profiles at time resolution of 1 hour for future years. The Z score range …
Published in Research & Reviews : Journal of Statistics · Vol. 14, Issue 1, 2025 · pp. 38–48 Read article
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Quick Reach Alert System
Abstract: This project presents the design and implementation of a compact and low-cost GPS tracking system using the A9G module. The system is capable of tracking real-time location, sending emergency alerts, and providing audio surveillance. It includes an SOS button that, when pressed, immediately sends the user’s current GPS location via SMS to a predefined phone number. Additionally, the system allows remote audio monitoring through a microphone connected to the A9G …
Published in Journal of Communication Engineering & Systems · Vol. 15, Issue 3, 2025 · pp. 34–40 Read article
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Interior Design for Disaster Resilience
Abstract: In the age of heightening environment actuated calamities and the thriving intricacy of metropolitan scenes, the basic to implant catastrophe flexibility inside plan resounds with remarkable criticalness. This examination paper embraces a general odyssey, diving into the complicated interchange between inside plan and catastrophe flexibility inside the constructed climate. Drawing upon a tremendous embroidery of insightful writing, exact investigations, and genuine models, the paper fastidiously disentangles the multi-layered methodologies, developments, …
Published in International Journal of Climate Conditions · Vol. 1, Issue 1, 2024 · pp. 01–15 Read article
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Biomimicry of Eucalyptus Leaf Design for Optimization and Fabrication of Airfoil
Abstract: Biomimicry is the practice of drawing inspiration from natural forms to solve engineering problems, which has become progressively popular for refining design efficiency and performance. This work discovers how biomimicry can be applied to airfoil design, precisely through the unique structure of Eucalyptus leaves, a concept rarely explored in airfoil profiling. The work presented here, focuses on enhancing airfoil designs by incorporating the intricate features of these leaves. The airfoil …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 359–372 Read article
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Application of Artificial Intelligence in Drug Discovery
Abstract: The application of artificial intelligence (AI) in medicine, especially through machine learning (ML), is revolutionizing new-age drug discovery research. AI is found as an efficient and powerful tool to narrow the gap between disease detection and developing and identifying potential therapeutic agents for a cure. This review provides a summary of the latest developments in AI and its potential application in drug discovery for untreatable diseases. The review also examines …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 22–29 Read article
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Smart Ways to Manage Waste with AI and IOT: A Review
Abstract: Rapid urban growth and population have led to exponential growth in municipal solid waste over traditional inefficient waste management systems (collection / segregation / disposal). This paper reviews the convergence of Internet-of- Things (IoT) and artificial intelligence (AI), seen as two potential smart techniques to launch smarter waste management. The research reports important applications for AI and IoT in waste classification, waste collection optimization, waste-to-energy as well as smart bin …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 26–31 Read article
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Effect of Span, Load Intensity, and Beam Geometry on Stress and Deflection Behavior of RCC Beams
Abstract: This study investigates the influence of variations in beam geometry, span, load intensity, and permissible stresses on the structural behavior of reinforced concrete beams. Using classical bending and shear stress formulations, the effects of a 20% increase in key parameters were analytically evaluated. Results indicate that a 20% increase in beam span leads to a proportional 20% increase in beam depth, whereas a 20% increase in beam width or permissible …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 1, 2026 · pp. 9–22 Read article
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Quantum Mechanics: Revolutionizing Pharmaceutical Sciences
Abstract: Quantum physics and pharmacy have generally been regarded as distinct areas—one investigates the microlevel behavior of non-living matter while the other concentrates on intricate biological systems. Nevertheless, progress in life sciences has increasingly depended on molecular-level insights, whereas quantum physics has advanced beyond basic principles to impact real-world uses. This intersection provides new opportunities for, pharmacy. Quantum entanglement, which allows for instantaneous relationships between particles, can be utilized for secure …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 72–77 Read article
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Navigating the Antenna Frontier for Emerging IoT Technologies
Abstract: Internet of Things (IoT) is rapidly transitioning from niche applications to a pervasive, interconnected fabric of intelligent devices, demanding unprecedented levels of performance, reliability, and miniaturization from its constituent components. At the heart of this revolution lies the antenna, the crucial interface between the digital and physical realms. This paper delves into the intricate and evolving landscape of IoT antenna design, specifically addressing the unique challenges and opportunities presented by …
Published in International Journal of VLSI Circuit Design & Technology · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article