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620 articles for “Pharma”
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Sustainable Innovations in Green Nanotechnology for Nanoparticle Synthesis
Abstract: Green nanotechnology is an emerging field that focuses on the environmentally friendly production of nanoparticles through biological and sustainable processes. This approach has diverse applications across industries such as pharmaceuticals, energy, electronics, and bioengineering. Compared to conventional methods, biologically driven nanoparticle synthesis, particularly utilizing green chemistry principles, offers a safer, eco- friendly, non-toxic, and cost-effective alternative. Metal nanoparticles are commonly synthesized through top-down and bottom-up strategies using physical, chemical, and …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 3, Issue 1, 2025 · pp. 31–37 Read article
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A Review: Homeopathic Remedies and Their Potential Neurological Implications in Depression and Asthma
Abstract: Homeopathy, based on the principle “like cures like”, has gained popularity as a complementary treatment for chronic diseases, including depression and asthma. Both health conditions have a profound impact on the quality of life of individuals and are often treated with pharmacological interventions such as antidepressants and bronchodilators. This review reviews homeopathic remedies used to treat depression and asthma, evaluating the available clinical evidence. Although some studies suggest that homeopathy …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 1, 2025 · pp. 15–20 Read article
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Modeling and Simulation of Feed Forward Temperature Controller with Effect of Higher Gain on Chemical Reactors Heat Exchangers
Abstract: Chemical reactors are widely used in pharmaceutical process industries. The temperature controller design is an essential part of heat exchangers (HE) design for such reactors. The goal of this research is to design and validate the Feed Forward (FF) temperature compensator for the stared tank chemical rectors. The aim is to analyze the impact of high turbulence (Gain) performance on step response. For temperature management, a transfer function (TF) control …
Published in Journal of Thermal Engineering and Applications · Vol. 12, Issue 1, 2025 · pp. 30–40 Read article
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A Review on the Magical Plant : Shatavari (Asparagus racemosus)
Abstract: Shatavari (Asparagus racemosus) is a revered medicinal herb in Ayurveda, recognized for its diverse health benefits, particularly for women’s health. The chemical makeup, pharmacological characteristics, and therapeutic uses of shatavari are thoroughly examined in this review. Key active compounds include saponins, flavonoids, and phytoestrogens, which contribute to its adaptogenic, antioxidant, and hormone-regulating effects. These properties make Shatavari effective in addressing female reproductive issues, such as infertility, irregular menstrual cycles, and …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 32–43 Read article
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Inventory of Healthcare Waste Generated at Kambia Government Hospital, Sierra Leone
Abstract: This research studies the categories and management practices of healthcare waste generated at Kambia Government Hospital and stresses the need for effective waste management to protect health and the environment. The waste is categorized into seven types: general, infectious, pathogenic, pharmaceutical, sharps, chemical, and liquid. Weekly assessments discovered fluctuations in waste generation, with general and infectious waste consistently comprising significant portions. Notably, sharps waste underscored the risks associated with injury …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 20–28 Read article
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A Comprehensive Review on Coumarin Derivatives
Abstract: Coumarins are naturally occurring compounds found in plants, fungi, and microorganisms with diverse bioactivities. They have antithrombotic, anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, and neuroprotective properties. Extracting coumarins, using methods like maceration and microwave- assisted extraction, is crucial for their applications. However, safety and toxicology are important, especially in pharmaceuticals, cosmetics, and food additives. Consuming moderate amounts of coumarin-rich foods is generally safe, but excessive intake raises concerns about hepatotoxicity and …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 72–80 Read article
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Visualization of genomic sequence in BRCA1 and BRCA2
Abstract: Heredity is the main reason of breast cancer in women and mutation or genetic variations also another reason for the spread of breast cancer. Heredity and genetic variations are responsible 5%-10%, 30%-50% respectively. There are 90% chances of developing neoplasm by the mutations. The effect of BRCA1 and BRCA2 may leads to the variations in DNA therefore it should be in limited amounts so that there will be minimum changes …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 49–55 Read article
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Role of Carboxylesterases in Xenobiotic Metabolism and Detoxification: Insights for Cheminformatics Approaches
Abstract: Xenobiotics, which include a wide range of environmental pollutants, food additives, drugs, and carcinogens, are foreign chemical entities that enter the human body and may accumulate, leading to toxic effects. Phase I and phase II metabolic responses are among the detoxification procedures that are necessary to lessen these negative consequences. This review highlights the pivotal role of carboxylesterases (CES), enzymes involved in the hydrolysis of ester, amide, and thioester bonds …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 9–17 Read article
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In Silico Exploration of Podophyllum Hexandrum-Derived Phytocompounds as Potential Therapeutics Against Small Cell Lung Cancer (SCLC): A Molecular Docking Approach
Abstract: Small Cell Lung Cancer (SCLC) is a fast-growing and aggressive type of lung cancer that spreads quickly strongly associated with smoking. It is characterized by symptoms, such as persistent cough, breathing difficulties, or hoarseness, though it can sometimes be asymptomatic which makes early detection challenging. The tumor suppressor gene TP53 is critical in regulating the cell cycle and preventing uncontrolled cell division. Mutations in TP53 result in the loss of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 1, 2025 · pp. 1–11 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Treated Sewage in Fish Farming and Ecological Challenges
Abstract: The use of treated sewage in fish farming presents a sustainable and cost-effective approach towards resource conservation and aquaculture productivity. Treated sewage is enriched with essential nutrients, like nitrogen and phosphorus, which supports the growth of aquatic plants and phytoplankton. These are vital components of aquaculture ecosystems. This practice reduces freshwater dependency and mitigates waste disposal challenges as well as aligns with circular economy principles. Pilot projects in China and …
Published in International Journal of Marine Life · Vol. 2, Issue 1, 2025 · pp. 26–31 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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An Insightful Study on SMEDDS Challenges and Potential Strategies
Abstract: Self-microemulsifying drug delivery systems (SMEDDS) have gained attention as an effective approach to enhance the bioavailability of poorly water-soluble drugs. They are innovative lipid-based formulations designed to enhance the solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs. The development of SMEDDS involves systematic selection of components based on solubility and emulsification efficiency, followed by optimization of ratios using pseudo-ternary phase diagrams. The resulting formulations are evaluated for droplet size, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 311–334 Read article
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Effectiveness of Habb-e-Suranjan and Roghan-e-Farfiyun in the Management of Waja-ul-Rukba (Knee Pain): A Review
Abstract: Introduction: Knee osteoarthritis is a painful condition that represents the degeneration of the cartilage and osteophyte formation in the knee joint, which affects millions of people worldwide. According to the Unani claimed text, accumulation of “madda” (substance) in joints, which is neither absorbed nor expelled, is due to the absence of Quawwat-e-Jazibah (power of absorption) and Quawwat-e-dafia (power of expulsion). Unani medicine presents a promising approach for managing knee osteoarthritis …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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Optimization Of Solar Drying Parameters for Turmeric and Papaya Leaves: Effects on Nutritional and Bioactive Compound Retention
Abstract: This study focuses on the optimization of solar drying parameters for turmeric and papaya leaves, based on their impact on retention of nutritional and bioactive compounds. One of the most crucial postharvest procedures is solar drying as it decreases the moisture content in plant materials, thereby increasing shelf life and preserving quality. This study considers traditional methods as open sun drying (OSD) and advanced solar dry techniques, including Hybrid Indirect …
Published in International Journal of Electrical Power and Machine Systems · Vol. 3, Issue 1, 2025 · pp. 29–37 Read article
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A research study into the interactions between the monoherbal formulations of arjuna and Aloe vera in a rat model of isoproterenol-induced cardiotoxicity
Abstract: Aloe vera is a herbal dietary supplement, and arjuna is used for its cardioprotective properties. Rats were given isoproterenol hydrochloride subcutaneously to cause myocardial infarction. The purpose of the study was to identify any potential pharmacodynamic interactions between the commercially available formulations of Aloe vera and arjuna. Materials and Procedures: The electrocardiogram (heart rate, ST segment elevation time, QRS complex amplitude), serum cardiac markers (creatine kinase, isoform of creatine kinase, …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 1–10 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Chemiluminescence: Recent Developments and Photochemical Applications in Analytical Chemistry
Abstract: Chemiluminescence (CL) is the observable production of electromagnetic radiation from a chemical reaction, typically in the form of ultraviolet, visible, or infrared light. According to subjective yield, CL has either been directly emitted from electronically excited intermediate products, or it has been supported by another molecule to emit CL. Since the 1950s, CL has been supported as a valid analytical tool, with the descriptive issued scope being limited to content …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 1, 2024 · pp. 20–25 Read article
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Review on Sustained Released Matrix Tablet
Abstract: Pharmaceuticals often use sustained release dose forms to prolong the therapeutic agent’s presence in the bloodstream and maintain a consistent plasma profile. The matrix governs the drug’s release rate. Hydroxypropyl methyl cellulose, a release retardant, is a key excipient in formulations due to its ability to promote sustained release. Techniques that include wet granulation, direct compression, or the dispersion of solid particles within a porous matrix, integrating polymers, like polymethyl …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 60–69 Read article
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CdS-Based Photocatalytic Nanostructures: A Promising Material for Various Environmental Applications
Abstract: Modern technological and industrial progress has significantly increased the use of chemicals in product development, leading to greater contamination of water sources by conventional pollutants (such as organic dyes and heavy metals) and harmful microorganisms. Wastewater treatment processes now reveal “emerging pollutants,” including pharmaceuticals, endocrine disruptors, and agricultural chemicals. Certain emerging pollutants, though harmless in some cases, can pose serious risks to various organisms. To address this, researchers are exploring …
Published in Research & Reviews : Journal of Physics · Vol. 14, Issue 1, 2025 · pp. 33–53 Read article