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720 articles for “Vit D”
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Design and Evaluation of Thermo-Responsive Poly(N-isopropylacrylamide)-Based Polymeric Nanoparticles for Temperature-Triggered Intratumoral Release of Doxorubicin in Solid Tumors
Abstract: Thermo-responsive polymeric systems have emerged as promising platforms for targeted intratumoral drug delivery in cancer therapy. This study aimed to develop and evaluate poly(N-isopropylacrylamide) (PNIPAM)-based polymeric nanoparticles as intelligent carriers for temperature-responsive delivery of doxorubicin (DOX) to solid tumors. Nanoparticles were synthesized via free radical polymerization using N-isopropylacrylamide as a thermoresponsive monomer and N,N′-methylenebisacrylamide as a crosslinker, forming a stable network with a tunable lower critical solution temperature (LCST).The optimized …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 159–168 Read article
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Sustainable Cotton Crop Productivity through Precision Weed Detection: A Deep Learning-Based Approach with UAV Integration
Abstract: Weeds present a major challenge to crop productivity by competing with crops for vital resources, including water, sunlight, and nutrients, often resulting in significant yield reductions. On a global scale, weeds are responsible for approximately 13.2% of annual crop losses, a quantity sufficient to feed nearly one billion people. These invasive plants disrupt agricultural systems and adversely impact crop yields. Given their uneven distribution in fields, ground or aerial robots …
Published in Journal of Aerospace Engineering & Technology · Vol. 15, Issue 1, 2025 · pp. 19–26 Read article
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Formulation and Evaluation of Herbal Skin Cream
Abstract: Herbal cosmetics have gained significant attention in recent years due to increasing consumer preference for natural and safe skincare products. Herbal skin creams are semisolid formulations enriched with plant-derived ingredients that provide therapeutic as well as cosmetic benefits. These formulations are designed to enhance skin health by utilizing bioactive phytoconstituents such as flavonoids, alkaloids, tannins, essential oils, and vitamins. Herbal creams are generally prepared using oil-in-water (O/W) or water-in-oil (W/O) …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 20–32 Read article
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A Review Paper on The Mathematical Foundations of Artificial Intelligence
Abstract: Artificial Intelligence (AI) is deeply rooted in various branches of mathematics, which provide the theoretical foundation and practical tools for developing intelligent systems. This paper explores the crucial role of mathematics in AI, focusing on key areas such as Linear Algebra, Probability and Statistics, Optimization Techniques, Calculus, Graph Theory, and Fourier and Wavelet Transforms. Linear Algebra is fundamental for representing and manipulating data, with applications in dimensionality reduction and neural …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 3, 2025 · pp. 7–14 Read article
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Revolutionizing Culinary Innovation and Sustainability through Smart Kitchen Assistant
Abstract: Introducing a Smart Kitchen Assistant which revolutionizing a culinary experiences with advanced features. This innovative system integrates a precision Vegetable Cutter, optimizing meal preparation efficiency. And a Storage Space ensures organized ingredients readily available for cooking. UV Light Sterilization guarantees hygienic food preparation surfaces, enhancing safety. Additionally, integrated Solar Panels promote sustainability, reducing energy consumption and environmental impact. By seamlessly combining this technology with sustainable practices, our Smart Kitchen Assistant …
Published in Trends in Machine design · Vol. 11, Issue 3, 2024 · pp. 1–16 Read article
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Treated Sewage in Fish Farming and Ecological Challenges
Abstract: The use of treated sewage in fish farming presents a sustainable and cost-effective approach towards resource conservation and aquaculture productivity. Treated sewage is enriched with essential nutrients, like nitrogen and phosphorus, which supports the growth of aquatic plants and phytoplankton. These are vital components of aquaculture ecosystems. This practice reduces freshwater dependency and mitigates waste disposal challenges as well as aligns with circular economy principles. Pilot projects in China and …
Published in International Journal of Marine Life · Vol. 2, Issue 1, 2025 · pp. 26–31 Read article
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Integrating Ayurveda in Infertility Management: A Case Study on Fimbrial Blockage
Abstract: Infertility significantly impacts a woman’s psychological and physical health, as well as that of her family. Fallopian tube blockage is one of the leading causes of female infertility, accounting for a substantial number of cases globally. Conventional medical approaches, including in vitro fertilization (IVF) and surgical procedures, often present barriers due to their high cost, invasive nature, and limited accessibility. Additionally, cultural, financial, and personal considerations can further restrict their …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 12–19 Read article
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Log Identification and Monitoring System Using Generative AI
Abstract: In contemporary software ecosystems, application and infrastructure logs play a vital role in ensuring system reliability, performance optimization, fault diagnosis, and security compliance. As applications become increasingly distributed and cloud native, the volume, velocity, and variety of generated log data have grown dramatically. This rapid expansion makes traditional manual log inspection inefficient, error-prone, and largely impractical. To address these challenges, this paper proposes an artificial intelligence (AI) driven log monitoring …
Published in Journal of Computer Technology & Applications · Vol. 17, Issue 1, 2026 · pp. 08–16 Read article
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Determination of Free Chlorine Water Content in Jalandhar City Using Colorimeter
Abstract: Water is the ultimate source of life on this universe. Water is vital for the survival of humans, animals, and plants, and the issue of freshwater is becoming increasingly critical in society. With the human body composed of 64% water, contaminated water, inadequate waste disposal, and poor water management contribute to severe public health issues such as cholera, typhoid, and malaria annually. Globally, the quality and quantity of water are …
Published in Journal of Water Pollution & Purification Research · Vol. 11, Issue 1, 2024 · pp. 1–5 Read article
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Trends and Applications of Artificial Intelligence in Mechanical Engineering: A Review
Abstract: Artificial Intelligence (AI) has become a revolutionary force across various fields, including mechanical engineering, where it is redefining traditional approaches to design, manufacturing, maintenance, and overall system optimization. This review aims to provide a comprehensive introduction to AI and explore its diverse applications within the domain of mechanical engineering. The study begins with a foundational overview of AI, including key concepts such as machine learning, neural networks, deep learning, and …
Published in Journal of Mechatronics and Automation · Vol. 12, Issue 3, 2025 · pp. 30–35 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Challenging Chauvinist Ideology in Bollywood
Abstract: This paper explores about how women has been challenging ideology that has its roots embedded since a long time. The portrayal of women in movies has now changed the perspective and resulting in shaping mindset of people towards women. This paper examines women centric movies which put greater impact in Indian society and also deals with this rapidly changing role of women in Indian cinema. The roles played by the …
Published in International Journal of Trends in Humanities · Vol. 1, Issue 2, 2024 · pp. 01–08 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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Nutrient-Mediated Activation of Cellular Signaling Pathways: Mechanistic Insights into Attenuation of Toxin Induced Inflammation in Food Animals
Abstract: Dietary and environmental toxins remain a persistent challenge in food animal production, where subclinical and clinical inflammation compromises health, productivity, and food safety. Toxin induced inflammation is driven by oxidative stress, mitochondrial dysfunction, and dysregulated immune signaling, resulting in impaired metabolic efficiency and increased disease susceptibility. Recent advances in nutritional science have revealed that nutrients act not only as substrates for growth but also as signaling molecules capable of modulating …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 1, 2026 · pp. 1–12 Read article
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Geotechnical Analysis and Performance Evaluation of Subgrade Materials in Road Construction
Abstract: Geotechnical engineering plays a pivotal role in the design, construction, and long-term maintenance of infrastructure, particularly in road construction, where subgrade conditions are directly linked to pavement performance, durability, and overall structural integrity. The performance of a road is heavily influenced by the geotechnical properties of the subgrade, making it essential to thoroughly assess these properties in the planning and construction phases. This study comprehensively investigates the geotechnical characteristics and …
Published in Journal of Geotechnical Engineering · Vol. 11, Issue 3, 2024 · pp. 24–29 Read article
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Rapid Post-uterine Involution in Dairy Cows: Mechanisms, Dietary Strategies, and Impact on Postpartum Recovery
Abstract: The postpartum period in dairy cows is critical for reproductive success, with uterine involution playing a central role in returning the reproductive tract to its pre-pregnancy state. Rapid uterine involution is essential for improving reproductive performance and minimizing the risk of postpartum complications. This review explores the nutritional mechanisms that influence uterine involution, focusing on key dietary strategies to promote tissue repair and recovery. We examine the role of energy, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Chronic Obstructive Pulmonary Disease (COPD) in Younger Adults: Challenges and Considerations – A Review
Abstract: Chronic Obstructive Pulmonary Disease (COPD) phenomenon rapidly converting into chronic significant health issues for many young adults. A disease calculated for older age gives way to early-onset COPD, which creates new issues for diagnosing and treating the illness and even interacts with the quality of life. The article reviews the epidemiology, risk factors, pathophysiology, clinical presentation, and treatment considerations related to this set of conditions. From those risk factors, early-onset …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 08–19 Read article
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Prevention of Water Overflows and Leakages at MPCOE Campus
Abstract: Water is one of the fundamental necessities of human life, essential for a wide range of daily activities. People rely on water for drinking, cleaning, cooking, irrigation, and industrial processes. To meet these needs, water is often pumped from ground storage to overhead tanks. However, the use of non-automated switches to operate pumping machines can lead to significant issues, such as water overflow and unnecessary electricity consumption. The proposed system …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 1, 2025 · pp. 43–51 Read article
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Neuroprotective Effects of Curcuma longa: A Review of Its Role in Neurodegenerative Diseases
Abstract: Curcuma longa (turmeric), a perennial herb notably utilized in traditional medication, has garnered big clinical attention due to its major bioactive compound, curcumin. Curcumin, well-known shows a couple of organic activities, together with antioxidant, anti-amyloidogenic, and neurodegenerative effects, making it a promising candidate for the management of neurodegenerative diseases (NDDs), which include Alzheimer’s illness, Parkinson’s disorder (PD), Huntington’s sickness (HD), and amyotrophic lateral sclerosis (ALS). This evaluate consolidates current findings …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 24–32 Read article