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Research & Reviews: A Journal of Pharmacognosy Review Article

Neuroprotective Effects of Curcuma longa: A Review of Its Role in Neurodegenerative Diseases

  1. Archana Kumari Department of Pharmacy, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi, Solan
  2. Priya Sharma Department of Pharmacy, School of Pharmacy and Emerging Sciences, Baddi University of Emerging Sciences & Technology, Baddi, Solan

Abstract

Curcuma longa (turmeric), a perennial herb notably utilized in traditional medication, has garnered big clinical attention due to its major bioactive compound, curcumin. Curcumin, well-known shows a couple of organic activities, together with antioxidant, anti-amyloidogenic, and neurodegenerative effects, making it a promising candidate for the management of neurodegenerative diseases (NDDs), which include Alzheimer’s illness, Parkinson’s disorder (PD), Huntington’s sickness (HD), and amyotrophic lateral sclerosis (ALS). This evaluate consolidates current findings at the neuroprotective mechanisms of curcumin, its pharmacokinetics, bioavailability demanding situations, and its utility in medical settings. Emphasis is laid on in vitro and in vivo studies, as well as scientific trials assisting the efficacy of curcumin in mitigating neurodegenerative pathologies. Advances in nano formulation techniques aimed at enhancing its mind-targeted shipping are also mentioned. Universal, curcumin emerges as a multifaceted neuroprotective agent with translational relevance within the prevention and treatment of NDDs.

Keywords

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