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538 articles for “efficacy”
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Exploring Chicken Sternal Cartilage as an Alternative Source of Bioactive Protein Hydrolysates
Abstract: There is a growing concern on the correct use and dispose of the by-products of the food industry, and chicken slaughterhouse, such as cartilage, combs, and wattles may be strong candidates as a protein source for bioactive peptides, however it is crucial to understand how the proteolysis process may affect the peptide profile and their bioactivity. The objective of this work was to obtain protein hydrolysates from chicken sternal cartilage …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 3, 2025 · pp. 15–28 Read article
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Solubility Enhancement Technique for Verapamil by Solid Dispersion Method
Abstract: By creating a solid dispersion, this study aimed to address the limitations of the traditional solid dosage form of verapamil, including its low bioavailability and restricted clinical efficacy. In order to alter the drug's release and improve its solubility, verapamil solid dispersion was created using the Solvent Evaporation Method and Fusion Method. The physical state of the solid dispersed verapamil was determined using saturation solubility testing and dissolution studies. Verapamil …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 94–99 Read article
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Exploring AI-Driven Student Performance Analysis as a Dimension of an AI-Powered Assessment and Feedback System: A Comprehensive Review
Abstract: The rapid proliferation of artificial intelligence (AI) in educational technology has heralded a paradigmatic transformation in assessment methodologies, transitioning from static, summative evaluations to dynamic, data-driven systems that emphasize continuous formative feedback. This comprehensive review interrogates AI-driven student performance analysis as a cardinal dimension of AI-powered assessment and feedback systems (AI-PAFS), synthesizing findings from forty-five rigorously curated open-access empirical studies published between 2015 and 2024. Employing a methodological lens, the …
Published in Current Trends in Information Technology · Vol. 16, Issue 1, 2025 · pp. 24–31 Read article
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Exploring the Potential of AI-Driven Personalized Learning and Cognitive Interventions for ADHD Management in Indian Children and Adolescents: A Focus on Early Intervention
Abstract: Attention Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental condition that significantly impairs attention, executive functioning, and behavioural regulation in children and adolescents. In India, the management of ADHD is particularly challenging due to low public awareness, social stigma, and a critical shortage of specialized mental health services, especially in rural areas. These systemic barriers often lead to delayed diagnoses and limited access to consistent care. However, with the rapid …
Published in International Journal of Brain Sciences · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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A Review on Applications of Artificial Intelligence (AI) in Parkinsons’s Disease Diagnosis and Treatment and Its Future Challenges
Abstract: Parkinson’s disease (PD) is a long-term, progressive neurodegenerative disorder that mainly occurs in people older than 60 years, affecting nearly 1% of this population. It is chiefly marked by the loss of dopaminergic neurons in the substantia nigra, a crucial brain region responsible for controlling motor functions. The resultant dopamine deficiency significantly disrupts motor control, manifesting in clinical symptoms such as tremors, bradykinesia, muscle rigidity, and postural instability. While PD …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 3, 2025 · pp. 1–15 Read article
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Enhancing Surface Roughness of Polylactic Acid (PLA) 3D-Printed Parts Using CO₂ Laser Scanning: An Experimental Study on Parameter Optimization
Abstract: Fused deposition modeling (FDM) of polylactic acid (PLA) often suffers from poor surface finish due to the inherent layer-by-layer deposition process, limiting its use in high-precision applications. This study investigates CO₂ laser scanning as an efficient post-processing technique to reduce the surface roughness (Ra) of PLA parts while maintaining structural integrity. Specimens (100 × 80 × 5 mm) were fabricated with varying infill densities (35%, 70%, and 100%) to assess …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 503–511 Read article
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Development and Evaluation of a Cost-Effective UV-Protective Cream Containing Para-Aminobenzoic Acid and Aloe Vera for Indian Climatic Conditions.
Abstract: The increasing incidence of ultraviolet (UV) radiation-induced skin disorders has heightened the demand for effective, affordable photoprotective agents, especially in countries with high sun exposure such as India. This study aimed to develop a cost-effective and efficient UV-B protective cream formulation suitable for populations in Indian latitudes. Para-aminobenzoic acid (PABA) was selected as the primary sunscreening agent due to its high UV-B absorption efficiency, low toxicity, and affordability compared with …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 2, 2025 · pp. 7–18 Read article
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An Integrative Review of Male Sexual Disorders and the Therapeutic Role of Unani Aphrodisiacs
Abstract: Sexual health is a vital component of overall well-being, encompassing physical, emotional, and psychosocial dimensions. Male sexual dysfunction – including conditions, like erectile dysfunction, premature ejaculation, and low libido – can significantly impact quality of life and intimate relationships. Aphrodisiacs, derived from the Greek goddess Aphrodite, are substances that stimulate sexual desire and performance. Historically, natural aphrodisiacs have been used in various cultures and include plant-based substances such as Yohimbine, …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 8–15 Read article
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AI in Mental Health: New Developments and Prospects
Abstract: Artificial intelligence (AI) has revolutionised numerous industries, including the mental health care sector.In order to clarify present trends, ethical issues, and future prospects in this ever-evolving subject, this paper examines the integration of AI into mental healthcare. Recent research, AI application examples, and ethical issues influencing the area were all included in this study. Research and development trends and regulatory frameworks were also examined.With applications including the early detection of …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 3, 2025 Read article
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Challenges to Women's Adoption of the Human Papillomavirus Vaccine in India: An Updated Review
Abstract: The widespread availability of human papillomavirus (HPV) vaccines in some countries throughout the last ten years has demonstrated encouraging outcomes in reducing HPV infection and associated conditions including warts and precancerous lesions. We highlight vaccination coverage and efficacy in this study, which includes the most recent data on available HPV vaccinations. Furthermore, the topic of pan-gender immunisation and ongoing clinical trials is covered. Increasing vaccination coverage is now something that …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 21–30 Read article
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A Decade of Viral Evolution (2015–2025): Emergence, Mutations, and Implications for Global Health
Abstract: Over the past decade (2015-2025), viral evolution has profoundly reshaped the global health landscape, challenging healthcare systems, diagnostic tools, therapeutic strategies, and vaccine efficacy. This review comprehensively analyzes the evolutionary trajectories of major human and zoonotic viruses, with a focus on pandemic-prone, drug-resistant, and emerging pathogens. Viral evolution is driven by diverse molecular mechanisms including high mutation rates, recombination, reassortment, host immune pressure, and antiviral interventions, leading to genetic diversification, …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 31–40 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Co-Delivery of Multiple Therapeutic Agents
Abstract: The co-delivery of multiple drugs using advanced nanocarriers has revolutionized targeted therapy in various diseases, particularly in cancer, infectious diseases, and neurological disorders. Multi-layered polymeric nanocarriers (MLPNs) offer a sophisticated platform to encapsulate multiple therapeutic agents with precise control over drug release, bioavailability, and synergistic effects. These nanocarriers are designed with distinct polymer layers that enable sequential or simultaneous drug release based on stimuli-responsive mechanisms such as pH, temperature, and …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 406–419 Read article
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HPV Screening as an Alternative to Pap Smear in Cervical Cancer Prevention: A Comparative Study in North India
Abstract: Cervical cancer remains a leading cause of cancer-related morbidity and mortality among Indian women, especially in low-resource settings. While Pap smear testing has been the standard screening method, HPV DNA testing offers potential advantages in sensitivity, cost-effectiveness, and feasibility for large-scale implementation. This study compares the efficacy, cost, and acceptability of HPV screening versus Pap smears in urban and rural populations of North India. A comparative cohort study was conducted …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 31–37 Read article
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Regression Analysis of Topological Indices and Physicochemical Properties of Polymer-Based Anticancer Drugs
Abstract: The research analyzed the quantitative correlation between topological indices and the physicochemical properties of selected anticancer compounds using regression analysis. Various topological descriptors—such as the First Zagreb Index, Second Zagreb Index, and Forgotten Index were calculated and regressed against key molecular features, including polar surface area, melting point, and molar refractivity. The regression analysis revealed linear correlations between these topological indices and the properties of anticancer drugs, with particularly strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 255–267 Read article
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The Impact of Nanotechnology in Transforming Neuro-oncology - A Comprehensive Review
Abstract: The treatment of central nervous system (CNS) tumours, including aggressive malignancies like glioblastoma, faces significant challenges. The blood–brain barrier (BBB) blocks nearly 98% of small-molecule drugs from achieving therapeutic levels in the brain, and the heterogeneity of these tumours frequently contributes to treatment resistance and poor outcomes. Traditional approaches, including chemotherapy and radiotherapy, are hindered by systemic toxicity and inadequate drug penetration. Nanotechnology provides a promising alternative, as nanoparticles (NPs) …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 627–637 Read article
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Review on Formulation and Evaluation of Herbal Gel of Moringa oleifera and Aloe vera for management of acne
Abstract: Acne vulgaris is a prevalent chronic inflammatory disorder of the pilosebaceous units, characterized by excessive sebum production, follicular hyperkeratinization, bacterial colonization, and inflammation. Conventional therapies often result in side effects and the development of drug resistance, prompting the exploration of natural alternatives. This review highlights the potential of Moringa oleifera and Aloe vera in acne management via topical drug delivery systems (TDDS). Moringa oleifera is rich in bioactive compounds such …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 10–16 Read article
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Application of Priestia Megaterium in the Bioremediation of Petroleum Hydrocarbon Contaminated Environments
Abstract: Petroleum pollutants pose a serious and persistent threat to environmental ecosystems, particularly affecting soil and water quality. Effective and sustainable remediation strategies are crucial to mitigate their impact and safeguard environmental health. In this context, bioremediation—using microorganisms to degrade harmful contaminant —emerges as a promising and eco-friendly approach. The present study explores the biodegradation capabilities of the bacterium Priestia megaterium, a species previously recognized for its ability to break down …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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A Review of Telepharmacy: Advancements, Challenges, and Future Directions
Abstract: Like telemedicine, telepharmacy is a relatively new term that describes the delivery of pharmacological services. While tele comes from the Greek word “Telos,” which means from a distance, medicine comes from the Latin word “Meden,” which means to heal. The National Association of Boards of Pharmacy defines telepharmacy as the use of information and communication technology to provide patients with pharmaceutical treatment from a distance. Clinical pharmacy services are provided …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 1, 2026 · pp. 34–42 Read article
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Influence of Polymeric Carriers on the pH-Modifying Properties of Intracanal Medicaments in Root Canal Treatment
Abstract: Calcium hydroxide (CH) preparations and medicated gutta-percha are widely used intracanal medicaments in root canal treatment. These materials often incorporate polymeric carriers to deliver the CH payload and influence its therapeutic effect. This in-vitro study investigates the impact of different polymeric carriers on the pH-modifying properties of intracanal medicaments within the root canal system. The research focuses on two key aspects: (1) the ability of the polymers to control the …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 967–974 Read article
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Postbiotics Unveiled: Mechanistic Insights and Therapeutic Implications in Obesity.
Abstract: The burgeoning global obesity epidemic necessitates innovative therapeutic approaches, and postbiotics, bioactive compounds arising from microbial fermentation, have emerged as promising contenders in reshaping obesity management. This comprehensive review explores the multifaceted mechanisms by which postbiotics impact obesity, from modulating gut microbiota composition to influencing metabolic pathways and enhancing energy expenditure. The exploration of postbiotics is rooted in a deeper understanding of the gut–brain axis and bidirectional communication between gut …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 11–28 Read article