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715 articles for “Effectiveness of treatment”
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Pathways in Drug Discovery and Development: From Molecular Targets to Market Approval
Abstract: A complicated, multidisciplinary, and resource-intensive process, the discovery and development of new pharmacological drugs is essential to the advancement of contemporary medicine. Finding and optimising lead chemicals comes after a disease-relevant biological target has been identified and validated. Through preclinical research in animal models, these leads are thoroughly assessed for toxicity, pharmacokinetics, safety, and efficacy. Clinical trials, which are carried out in several stages to evaluate safety, efficacy, ideal dosage, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 1, 2026 · pp. 01–04 Read article
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Comprehensive Performance Assessment of Silane-Treated Bio-Extracted Husk Fiber Reinforced Composites for Sustainable Construction Applications
Abstract: This research project is an extensive experimental study on bio-extracted husk fiber polymer composites with a focus on silane surface treatment. Bio-extracted rice husk fibers underwent an alkali-enzymatic hybrid extraction process followed by a 3-aminopropyltriethoxysilane (APTES) treatment for improved interfacial adhesion and matrix compatibility. Resin composites with treated and untreated fibers were fabricated with a weight ratio of 10%, 20%, and 30% via hand lay-up methods. A battery of mechanical …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 229–241 Read article
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A Review on: Oral Thin Films: A New Approach to Effective and Easy Drug Delivery
Abstract: Oral Thin Film (OTF) is an advance drug delivery system in which drug is incorporated into dissolvable strip and place in oral cavity for rapid absorption. OTF is useful for patient such as pediatric and geriatric who have difficulty swallowing pills. It provides rapid action, precise dosage and improved bioavailability. OTFs consist of fast-dissolving films, extended-release films, and mucoadhesive films for various therapeutic applications. The manufacturing processes of OTFs such …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 22–41 Read article
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Design of Dual Media Water Filter Purifier Using Clay Pot
Abstract: Numerous organisations make low-cost water treatment devices for rural homes, for instance filters, RO and UV-based water purifiers. However, these devices have problems like filter clogging, the need to replace filters frequently water contamination (in the case of RO), and the truth that electricity is not always available in rural areas, which makes them costly to use. Because of this, RO and UV purifiers are too expensive for people who …
Published in Journal of Water Pollution & Purification Research · Vol. 12, Issue 3, 2025 · pp. 94–99 Read article
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Pharmacological Review On Enzalutamide
Abstract: A key therapeutic option in the treatment of prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), is Enzalutamide, a second-generation anti androgen drug. Enzalutamide, discovered by Charles Sawyer and Michael Jung at the University of California, Los Angeles, was developed and Food and Drug Administration (FDA)-approved in 2012. Its therapeutic significance was further solidified with subsequent extensions in indications to encompass metastatic castration-sensitive prostate cancer and non-metastatic castration-resistant prostate cancer. …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 7–15 Read article
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Flavonoids: An Answer to Chronic Diseases
Abstract: It has been shown that inflammation is closely associated with the onset or exacerbation of quite a few non-communicable human diseases. Several chronic diseases, such as cancer, diabetes, cardiovascular dysfunction and central nervous system damage are also developed following tissue injury produced by the high fragments of low-grade inflammation surrounding a compromised tissue or organ due to its acquired genomic changes. Current therapies for many of these diseases are associated …
Published in International Journal of Advance in Molecular Engineering · Vol. 2, Issue 1, 2024 · pp. 31–37 Read article
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Multidimensional Impacts on Bryophyllum Pinnatum for the Potential of Obesity: A Review
Abstract: Global public health concerns related to obesity are growing. Several comorbid illnesses, including cardiovascular disease (CVC), gastrointestinal disorders, type 2 diabetes (T2d), joint and muscle disorders, respiratory difficulties, and psychological disorders, are significantly more common in obese patients. The widespread misconception that obesity stems solely from a lack of self-control is gradually losing its stigma as awareness about fat-related issues grows. Instead of synthetic drugs herbal or medicinal plants are …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 42–51 Read article
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Improving Healthcare Outcomes with RF-enabled Health Information Systems
Abstract: Health Information Technology (HIT) plays a crucial role in improving healthcare by making medical data more accessible, accurate, and efficient. Using radio frequency (RF) technology, HIT enables the wireless sharing of important health information—like patient records, and treatments—between patients, doctors, and other healthcare providers. This helps reduce paperwork, cut costs, and improve the quality of care. By reducing the reliance on paper-based records, RF-based HIT helps streamline administrative processes, cut …
Published in International Journal of Radio Frequency Innovations · Vol. 3, Issue 1, 2025 · pp. 8–13 Read article
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Neuroinflammation Is Aggravated by the Aqueous Extract of Myrmecodia Platytyrea Tuber
Abstract: Myrmecodia platytyrea, commonly known as the ant plant, is a medicinal epiphyte traditionally used in Southeast Asia for its purported health benefits, including anti-inflammatory, antioxidant, antimicrobial, and anticancer activities. Its tuber contains abundant secondary metabolites, including flavonoids, tannins, phenolic compounds, and saponins. While these phytochemicals are generally associated with therapeutic effects, the biological activity of Myrmecodia extracts varies depending on the type of extract, dosage, and route of administration. In …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 5–14 Read article
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Bioremediation of Crude Oil-Contaminated Loamy Soil Using Plantain (Musa Paradisiaca) Stem Waste as a Biostimulant
Abstract: Crude oil contamination of soil is a pressing environmental challenge in oil-producing regions, especially in the Niger Delta of Nigeria. It degrades soil fertility, disrupts microbial ecosystems, and poses long-term ecological and health risks. Traditional remediation methods are often cost- prohibitive and environmentally intrusive, prompting the search for sustainable alternatives. This study investigates the potential of plantain (Musa paradisiaca) stem waste – a readily available agricultural byproduct – as a …
Published in Emerging Trends in Chemical Engineering · Vol. 13, Issue 1, 2026 · pp. 1–11 Read article
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Efficacy of Combination Therapy with Osimertinib and Afatinib in epidermal growth factor receptor-mutant non-small-cell lung cancer Patients
Abstract: Treatment options for patients with non-small-cell lung cancer who have epidermal growth factor receptor mutations are constrained by the emergence of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Osimertinib or afatinib alone, when tested in a laboratory model, led to the formation of drug-resistant clones harboring epidermal growth factor receptor secondary mutations. However, combining these drugs prevented the emergence of such mutations. In a Phase II clinical trial, …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 1, 2024 · pp. 13–24 Read article
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Bacterial Spectral in UTI in a Hospital Environment
Abstract: Urinary tract infections (UTIs) represent a significant public health issue, primarily caused by a variety of pathogens such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterococcus faecalis, and Staphylococcus saprophyticus. UTIs contribute substantially to illness and complications in individuals with pre-existing health conditions and account for a large portion of hospital visits globally. UTIs are usually self-limiting in people with no structural or functional problems, but they do tend to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Utilize Nature’s Power: Nutraceuticals in the Fight Against Dengue
Abstract: As dengue fever continues to surge across tropical and subtropical regions, the exploration of novel therapeutic approaches is crucial. Nutraceuticals, natural bioactive compounds derived from food sources, are emerging as promising adjuncts in the fight against this viral disease. Unlike conventional treatments that primarily target symptoms, nutraceuticals offer a complementary strategy by enhancing the body’s immune defense and addressing key complications. This review highlights the diverse potential of nature’s remedies, …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 1, 2025 · pp. 19–27 Read article
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Application of Drug Delivery using Nano- technology to Cure Mental Disorders (Schizophrenia)
Abstract: Nanotechnology involves the manipulation of the count at an atomic scale to create novel systems, materials, and devices. This groundbreaking era holds substantial potential for scientific development across various domain names, which includes manufacturing, patron items, electricity, substances, and remedies. In current times, the sphere of prescribed drugs has witnessed a brilliant surge in the usage of nanotechnology for the improvement of revolutionary medications. Schizophrenia, a neuropsychiatric disorder affecting the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 51–65 Read article
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Sphagneticola trilobata: A Green Treasure of Phytochemical Constituents and Medicinal Values
Abstract: Sphagneticola trilobata originally from the Caribbean, Mexico, and Central America, and is a plant of the Asteraceae family, tribe Heliantheae, that is now found growing across the Neotropics. The plant profile, key components, chemical test, and pharmacological actions of S. trilobata are all included in this review. The main constituents of the plant were limonene, bicyclogermacrene, α-humulene, α-pinene, α-phellandrene, and germacrene D, camphene, sabinene, 10-nor-calamenen-10-one, γ-amorphene. Which shows pharmacological active …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 15–21 Read article
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Investigating The Mechanical Properties of Sisal/Areca/Sisal Natural Fiber Reinforced Composite Material Treated with NaOH and Filled with Al2O3 and Tio2
Abstract: Biopolymer-based composites which are obtained from the natural resources like plants, animal or mineral based have recently attracted significant interest because they can be used in interesting ways in biology and materials science. These materials are generally non-toxic, reusable, and recyclable, which are useful in many situations where sustainability and environmental protection are important. Plant Based fibers like Bamboo, Coir, Kenaf, Banana, Sisal, hemp and jute are proving their potentiality …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 413–425 Read article
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A Comprehensive Review of Guillain-Barré Syndrome (GBS)
Abstract: The rare but potentially life-threatening immune-mediated condition dubbed Guillain-Barré syndrome (GBS) impacts the peripheral nerves and nerve roots and is generally brought on by infections. As was the scenario during the Zika virus outbreaks in Latin America (2015) and French Polynesia (2013), the incidence of GBS may consequently escalate during influenza outbreaks. Considering GBS’s clinical features and ailments course are multiple and there are currently no global clinical guidelines, the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 1–5 Read article
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Mechanical Characterization of Kevlar 49 and Pina Fiber Hybrid Composites
Abstract: The pursuit of sustainable yet high-performance materials has accelerated research into hybrid composites that combine synthetic and natural fibers. This study investigates the fabrication and characterization of a Kevlar 49/Pina fiber hybrid composite using epoxy resin as the matrix. Kevlar 49, known for its exceptional tensile strength and energy absorption, was employed as the face sheet material, while Pina fiber, a biodegradable reinforcement extracted from pineapple leaves, was incorporated as …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 301–316 Read article
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Selection of Ionic Liquids for the Design of Separation Processes of CO₂ + H₂S Mixed Waste Gases with Different Compositions
Abstract: The waste gas from chemical plants contains H 2 S gas and a large amount of CO 2 gas. These flue gases can be treated in various ways, and in this paper, the mixed flue gas CO 2 +H 2 S was treated by using ionic liquids (IL) as an absorbent. Ionic liquids are considered green solvents with remarkable good properties. In particular, it is known as a very effective …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 44–58 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article