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224 articles for “structural validation”
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Inhibition of PI3K/Akt/mTOR Signaling Pathway by Vitis Vinifera Phytocompounds: A Promising Strategy for Supressing Colorectal Cancer Growth and Metastasis
Abstract: Objectives: Colorectal cancer was not typically identified a few decades ago. Today, with almost 900 000 fatalities each year, it is the fourth most dangerous cancer in the world. Colorectal cancer is responsible for about 10% of all cancer diagnoses annually and cancer-related deaths worldwide. It is the second most common type of cancer in women and the third most common type in men. Incidence and death are roughly 25% …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 64–75 Read article
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Revolutionizing Geopolymer Composites: Unveiling Intelligent Wall Facades and Precision PZT Sensors for Vibration Analysis
Abstract: Evaluating the mechanical performance and environmental benefits of geopolymer composites is imperative for sustainable alternatives in construction. This study presents an innovative circular PZT-based sensor that effectively captures transient vibrations within concrete structures, demonstrating its validity in comparison to standard surface-mounted accelerometers. The research also elucidates the influence of sensor orientation on capturing various vibrational modes of concrete. Furthermore, the embedded PZT sensors provide valuable insights into the evolving mechanical …
Published in Journal of Polymer & Composites · Vol. 11, Issue 13, 2023 · pp. 59–73 Read article
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Bio-inspired Thermo-responsive and Self-Healing Polymer–PCM Hybrids for Next-Generation Smart Textile Applications
Abstract: The integration of phase change materials (PCMs) into flexible polymers represents a promising strategy for developing smart textiles with advanced thermal regulation and mechanical adaptability. However, the challenges of PCM leakage, poor mechanical strength, and durability under cyclic stress have limited their practical applications. In this study, we present a novel self-healing and elastic composite based on thermoplastic polyurethane (TPU) incorporating 30 wt% microencapsulated PCM (mPCM) and dynamic disulfide bonds …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 228–238 Read article
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From Baseline Survey to Management Plan: A Systematic Framework for Port-Specific Mitigation of Underwater Radiated Noise
Abstract: The growing recognition of underwater radiated noise (URN) as a significant marine pollutant necessitates the development of actionable management frameworks at the port level, where noise sources are concentrated, and impacts can be particularly acute. While international guidelines exist, a standardized methodology for ports to transition from assessment to implementation is lacking, particularly in regions with high biodiversity and developing maritime infrastructure. This paper presents and demonstrates a systematic, four-phase …
Published in Journal of Offshore Structure and Technology · Vol. 13, Issue 1, 2026 · pp. 22–30 Read article
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Generative Design of Bioactive Orthopedic Composites for Fracture Repair Using an Integrated Conditional GAN–Transformer Framework: A Multi-Objective Approach
Abstract: Orthopedic composite implants for fracture repair must simultaneously satisfy conflicting mechanical and biological demands: high fracture toughness, sufficient compressive stiffness, and bioactive surface chemistry enabling osteoblast adhesion and mineralization. Existing design approaches rely on trial-and-error experimentation, yielding sub-optimal trade-offs between these objectives. This paper presents an integrated conditional Generative Adversarial Network–Transformer (cGAN-T) framework for fully computational, multi-objective generative design of hydroxyapatite (HA)-reinforced polymer composite microstructures targeting Orthopedic fracture repair. A …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 21–35 Read article
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Predicting Dielectric Constants of Polymers Using Molecular Structural Descriptors and Explainable Machine Learning: A Data-Driven Approach
Abstract: Accurate prediction of dielectric constants in polymeric materials is fundamental to the rational design of advanced electronic components, energy storage capacitors, flexible substrates, and high-frequency communication circuits. Conventional approaches to identifying suitable polymer dielectrics rely on extensive experimental synthesis and characterisation, which are both time-consuming and resource-intensive. In this work, an explainable machine learning framework is developed to predict the dielectric constant of polymers directly from molecular structural descriptors derived …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 297–304 Read article
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Polymer–Gel Composite Phase Change Materials: A Functional Polymer Composite Approach for Solar-Thermal Energy Storage in Building Facades
Abstract: This study investigates polymer–composite phase change materials (PCMs) in the form of polymer–gel hybrids as multifunctional systems for solar–thermal energy storage in building façades. Paraffin- and PEG-based PCMs were embedded into polyurethane and acrylic gel matrices to create shape-stabilized polymer–composites with high PCM loading (70–80 wt%). Differential Scanning Calorimetry (DSC) confirmed distinct melting/freezing transitions at ~56°C (paraffin) and ~42°C (PEG), with enthalpy values of 120–150 J/g, closely matching theoretical predictions, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 36–51 Read article
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Effect of Fillet Radius on Bending Stress in Helical Gear using FEA
Abstract: A well-optimized change in root fillet radius could greatly benefit helical gear operation by providing a smoother transmission with less impact and noise. The fillet area of the gear root is an area of extensive bending stress concentration. An increase in fillet radius for helical gears is considered to minimise the bending stress at the gear tooth's base. This paper develops appropriate models of various gear tooth profiles of the …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 129–136 Read article
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Secured Communication and Image Authentication: Embedding Encrypted Text Files Into Color Digital Images
Abstract: In today's digital landscape, protecting digital assets, particularly images, is paramount. Researchers have developed various techniques to safeguard these assets, emphasizing their protection and integrity. Simultaneously, steganography plays a crucial role in securely communicating confidential messages. This paper focuses on a dual-purpose technique: watermarking color digital images for protection and embedding secret messages through steganography. This fusion of functionalities represents a significant step in comprehensive asset protection and confidential communication …
Published in International Journal of Information Security Engineering · Vol. 2, Issue 1, 2024 · pp. 10–15 Read article
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Facile Synthesis of SnO2/g-C3N4 nanocomposite for the photocatalytic degradation of Methylene Blue dye under visible light irradiation
Abstract: This work reports the nanoscale samples of pure tin dioxide (SnO₂), graphitic carbon nitride (g-C₃N₄), and their composite (SnO₂/g-C₃N₄) were successfully synthesized using the co-precipitation technique. The synthesized materials were extensively analyzed using multiple characterization techniques such as Powder X-ray Diffraction (PXRD), High-Resolution Scanning Electron Microscopy (HR-SEM), Energy-Dispersive X-ray Spectroscopy (EDAX), Fourier Transform Infrared Spectroscopy (FTIR), UV-Visible Spectroscopy, and High-Resolution Transmission Electron Microscopy (HR-TEM). Results from PXRD and EDAX confirmed …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1835–1845 Read article
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Impact of Clinical Simulation-Based Learning on Nursing Students’ Competency and Confidence: A Cross-Sectional Study
Abstract: Simulation-based learning (SBL) has emerged as a vital component in nursing education, offering students a safe, structured, and controlled environment to practice clinical skills. This study aimed to assess the impact of SBL on clinical competency and confidence among B.Sc. Nursing students. A cross-sectional study design was adopted, involving 120 B.Sc. Nursing students from Stephens College of Nursing, Stephens Group of Institutions, Jammu. Data were collected using a structured questionnaire …
Published in Journal of Nursing Science & Practice · Vol. 16, Issue 1, 2026 · pp. 11–16 Read article
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Design, Mathematical Modeling, and Dynamic Optimization of a Speed Breaker-Based Vehicular Kinetic Energy Harvester
Abstract: Decentralized energy harvesting methods are becoming more popular due to rapid urbanization and the rising need for sustainable infrastructure. The road-embedded vehicle kinetic energy harvester (VKEH) design, mathematical modelling, and experimental validation are presented in this work. This paper presents the structural engineering, continuum mathematical modeling, and experimental validation of an optimized road-embedded vehicular kinetic energy harvester (VKEH). The mechanism utilizes a spring- loaded, low-friction rack-and-pinion transmission coupled with a …
Published in International Journal of Electrical Power and Machine Systems · Vol. 4, Issue 2, 2026 Read article
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Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
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Quantitative Structure-activity Relationship in Computer-aided Drug Design: A Review
Abstract: Quantitative Structure-Activity Relationship stands at the forefront of Computer-Aided Drug Design, providing a systematic framework for understanding the relationship between the chemical structure of molecules and their biological activity. The present review delves into the multifaceted realm of quantitative structure-activity relationship methodologies within the landscape of drug discovery. Through an exploration of diverse quantitative structure-activity relationship models, molecular descriptors, validation techniques, and recent advancements, the present article aims to elucidate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 55–63 Read article
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ASSESSING OF FOREST STRUCTURE USING EARTH OBSERVATION DATA: ACASE STUDY IN MUNESSA FOREST, OROMIA REGION, ETHIOPIA
Abstract: Forest structure is essential for estimating forest-related carbon emissions, analyzing forest degradation, and quantifying the effectiveness of forest restoration initiatives. However, forest structure quantification is only limited to the specific area of interest without considering the whole forest coverage. Remote sensing data can easily deliver a large area to assess forest structure. Therefore, this study aims to assess forest structure of Munessa Natural Forest by integrating satellite based light detection …
Published in International Journal of Land Read article
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A Pre-experimental Evaluation of a Structured Educational Program on Awareness of Mosquito-borne Diseases in Senior Secondary School Students in Punjab
Abstract: Introduction: Mosquitoes constitute the most important single family of insects from the standpoint of human health. They are found all over the world. The four important groups of mosquitoes in India that are related to disease transmission are the Anopheles, Culex, Aedes, and Mansonia. Aims: The aims of the study are to assess the effectiveness of structured teaching program on knowledge regarding mosquito-borne diseases among students of senior secondary schools …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 2, Issue 1, 2024 · pp. 7–14 Read article
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DFT/Data Guided Predictive Modelling of Absorption Maxima in the OLED Rubrene Derivatives
Abstract: This study investigates the optical properties of rubrene derivatives to develop an accurate predictive model for absorption maxima using computational chemistry and chemoinformatic techniques. We benchmarked various quantum chemical methods, identifying that the M06-2X/aug-cc-pVDZ method in dichloromethane (DCM) provided the strongest correlation with experimental data. Key molecular descriptors such as band gap, ionization potential, and electrophilicity index were calculated and analyzed using principal component analysis (PCA) to identify significant factors …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 41–56 Read article
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Presenting the Model and Prioritization of Lean Production Success Drivers (Case study: Iran Khodro Company)
Abstract: The purpose of the current research is to present a model and prioritize the drivers of lean production success (case study: Iran Khodro Company). The statistical population and statistical sample of this study consists of 20 experts (managers) of Iran Khodro production department. In this research, first, the most important key success factors of lean production were determined using the validity technique of the content validity ratio, then the interpretative …
Published in International Journal of Sustainability · Vol. 1, Issue 1, 2024 · pp. 30–42 Read article
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Assessing Nanomaterial Toxicity and Environmental Behavior: Toward Sustainable and Safe Nanotechnology
Abstract: The rapid advancement of nanotechnology has introduced engineered nanomaterials into diverse sectors including medicine, agriculture, electronics, and consumer products. However, the unique physicochemical properties that make nanomaterials valuable also raise significant concerns about their potential toxicity to human health and ecological systems. This study presents a comprehensive survey-based analysis of 400 respondents from diverse professional backgrounds across seven countries to assess perceptions and understanding of nanomaterial toxicity mechanisms and environmental …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 28, Issue 1, 2025 · pp. 1–11 Read article
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Design and Structural Evaluation of a Dual-Axle Trailer Frame with a Focus on Increasing Strength While Aiming to Reduce Overall Weight
Abstract: The primary objective of this project is to evaluate various cross-sections and materials for the structural frame. The frame includes elongated side components and a central longitudinal member, which is connected to several cross-supports. The design focuses on optimizing both the cross-support layout and the choice of materials, incorporating composites to enhance performance. Load conditions are also altered to achieve improved efficiency. Static simulations are performed using ANSYS, while CATIA …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 2, 2025 · pp. 9–17 Read article