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256 articles for “screening”
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Enhancing Cancer Diagnosis: AI/ML Algorithms and Nanotechnology-Based Biosensors for Colorectal Cancer Screening
Abstract: Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide, and enhancing patient outcomes requires early identification. This study explores the potential of nanotechnology- enhanced biosensors and artificial intelligence/machine learning (AI/ML) algorithms to revolutionize colorectal cancer screening and diagnosis. Nanotechnology offers unique opportunities for the development of highly sensitive and specific biosensors capable of detecting cancer biomarkers at an early stage. By incorporating nanomaterials with exceptional optical, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 16–28 Read article
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Screening Some Sorghum (Sorghum Bicolor L. Moench) Genotypes for Yield and Resistance Against Stem Borer (Sesamia Calamistis) in Nigeria
Abstract: Sorghum is a staple crop with global significance, scientifically it’s known as Sorghum Bicolor, stands as one of the most important cereal crops globally, particularly in regions with arid and semi-arid climates. Sorghum remains a cornerstone of agricultural economies worldwide with its widespread cultivation and diverse applications; however, its production is often hindered by various biotic stresses, with stem borer (Sesamia calamistis) infestation being a significant concern. The stem borer …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 50–55 Read article
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In Silico Screening of Terminalia chebula Phytocompounds as Potential Inhibitors of NTCP and DDB1 in Hepatitis B Virus Infection
Abstract: Hepatitis B virus (HBV) infection is a major global health concern, and chronic carriers are at risk of developing cirrhosis, hepatocellular carcinoma (HCC), and even death. Existing treatments can effectively inhibit viral replication, but they achieve little eradication of the virus because of covalently closed circular DNA (cccDNA) retention. In this investigation, bioactive compounds of Terminalia chebula, a plant known for its hepatoprotective and antiviral properties in traditional medicine, were …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 33–44 Read article
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Screening of Mustard Varieties and Lines against Clubroot and Alternaria Leaf Spot Diseases
Abstract: The experiment was conducted to find out the resistant varieties/lines against clubroot and Alternaria leaf spot diseases of mustard at the Plant Pathology Division, RARS Jamalpur, Bangladesh during the Rabi season of 2024-2025 with sixty-two (62) varieties and lines of Mustard collected from Oilseed Research Centre (ORC) and Plant Genetic Resources Centre (PGRC), Joydebpur, Gazipur-1701, Bangladesh. To screen for clubroot and Alternaria leaf spot diseases and to evaluate yield and …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 97–106 Read article
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Screening of Pharmaceutically Significant Methioninase-Producing Fungi from the Satpura Range of Hoshangabad District and Its Large-Scale Production
Abstract: L-methioninase, an enzyme with notable anticancer properties, has emerged as a promising therapeutic agent due to its ability to selectively degrade methionine, a critical amino acid for the survival of methionine-dependent cancer cells. Methionine dependency, observed in many tumor cells, is a metabolic vulnerability that can be exploited for targeted cancer therapy. The Satpura Range in the Narmadapuram District, India, with its diverse microbial ecosystems, offers a rich reservoir for …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 33–43 Read article
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In-Silico Screening of Phytochemicals for Identification of Alternative Therapy for Thyroid Cancer
Abstract: Thyroid cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic alternatives to improve treatment outcomes. This study targets COT kinase (Cancer Osaka Thyroid Kinase), a protein implicated in the progression of thyroid cancer, using molecular docking methods with various phytochemicals to identify potential therapeutic compounds. PyRx and Discovery Studio were employed to evaluate the interactions and binding affinities of a diverse set of natural compounds with …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 31–55 Read article
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Synthesis of Silver Nanoparticles of Cissus Quandrangularis and It’s Virtual Screening Against Gastric Cancer
Abstract: Gastric cancer, also known as stomach cancer, is the third leading cause of cancer-related deaths globally and remains a major health challenge due to its poor prognosis and high mortality, largely attributed to late-stage diagnosis. In this context, plant-based nanomaterials are gaining momentum for targeted therapeutic applications. Cissus quadrangularis, a medicinal plant native to India from the Vitaceae family, is traditionally used for its diverse healing properties. Its stem, in …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1551–1569 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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Tinospora Sinensis Compounds for Zika Virus Targets 5JRZ and 5KVD In Silico Screening: A Potential Approach to Preventing Guillain-Barre Syndrome
Abstract: Objective: GBS is a very rare kind of disease but at the same time, it is very dangerous too. The study estimates that people who are suffering from zika virus infection are more prone to GBS. According to surveys, 1 out of 4000 people got affected by this disease, and the scariest part of this disease is that there is no cure available. In this computational era drug discovery is …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 2, 2023 · pp. 1–15 Read article
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Computational Screening of Vitex negundo Compounds for Potential Arthritis Therapies in India
Abstract: Objective: Arthritis is a pervasive medical condition that manifests as inflammation and discomfort within the joints. As of September 2021, arthritis has affected an estimated 180 million people in India, making it a substantial public health concern with a considerable impact on individuals' quality of life and healthcare systems. Therefore, using molecular docking, drug-likeness prediction, and ADME analysis, an effort was made to identify natural compounds from Vitex negundo, which …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 01–18 Read article
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A Screening Study on Occurrence and Distribution of Urinary Tract Infections Among Suspected Cases (Pyuria, With or Without Symptoms) During Pregnancy
Abstract: Background: Urinary tract infection is one of the most frequently seen medical complications in pregnancy. Methods: Ethical approval was granted for this research. The study employed a time-bound prospective design; total pregnant women (900) were categorized into those suspected of having UTI (pyuria, with or without symptoms) and those not suspected. Asymptomatic bacteriuria is diagnosed through a urine specimen with an appropriate microscopic examination, followed by culture. Results: The occurrence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 13–20 Read article
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Screening Phytocompounds of Tinospora cordifolia to Find Potential Drug Targets for Cystic Fibrosis
Abstract: This study aimed to evaluate the therapeutic potential of phytocompounds derived from Tinospora cordifolia in treating cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene that lead to severe respiratory and digestive complications. Phytocompounds were retrieved from the IMPPAT database and subjected to molecular docking simulations using PyRx to assess their binding affinity to the CFTR protein. The top-scoring compounds – sterol, magnoflorine, tembetarine, kaempferol, and …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 1, 2025 · pp. 16–24 Read article
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Edible Mushrooms: Management of Diabetes Mellitus and Phytochemical Screening of Agaricus Bisporus
Abstract: A metabolic disease characterized by elevated blood glucose levels; diabetes mellitus affects millions of people. If not treated on time, it causes problems, damage organs, and even life-threatening. Studies have shown that diabetes can be avoided and controlled with a healthy lifestyle that incorporates exercise and a balanced diet. While there are several synthetic medications available to treat this illness using them over an extended period of time is linked …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 1–13 Read article
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Screening of Newer Phytoconstituents on Novel Enzymes for their Biological Activity
Abstract: Background: Hyperlipidemia and gout are prevalent metabolic disorders significantly impacting global health. The xanthine oxidase and HMG-CoA reductase pathways play pivotal roles in the pathophysiology of these conditions. This study explores the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors for these enzymatic targets, offering insights into innovative therapeutic strategies. Aim: To evaluate the potential of natural phytoconstituents—daidzein, resveratrol, and genistein—as dual inhibitors of xanthine oxidase and HMG-CoA reductase …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 1, 2025 · pp. 81–86 Read article
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Phytochemical Screening and Biological Activity of Pomegranate Extracts
Abstract: Pomegranates are renowned for their abundance of bioactive compounds that exhibit potent antioxidant, anti-inflammatory, and antimicrobial properties, making them a subject of growing interest in natural medicine. This study aimed to compare the biological activities of ethanolic extracts derived from different parts of the pomegranate plant—specifically, the bark, peel, and leaves. A comprehensive investigation was conducted to evaluate their phytochemical composition and assess their antimicrobial, antioxidant, and anticancer properties. The …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 64–79 Read article
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In Silico Screening and Molecular Docking of Cynodon dactylon phytochemicals against COPD-Associated Proteins
Abstract: Chronic Obstructive Pulmonary Disease or COPD is a pulmonary disease that obstructs airways and alveoli accompanied by respiratory issues like emphysema and bronchitis. This disease is caused mainly by inflammatory responses of the body to foreign particles that enter the respiratory path including tobacco smoke, air pollutants and irritants. The hallmark of COPD is excessive inflammation caused by imbalance in protease anti-protease activity. Proteases like elastase breakdown the ECM of …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Awareness Regarding Cervical Cancer among Women Attending a Selected Hospital in Lucknow, Uttar Pradesh: A Cross-Sectional Study.
Abstract: Cervical cancer continues to be a significant health concern, particularly in low- and middle-income countries like India, where it remains a leading cause of cancer-related deaths among women. Despite the availability of preventive measures such as the Human Papillomavirus (HPV) vaccine and screening techniques like Pap smears, a considerable gap in awareness persists. Limited knowledge of cervical cancer, its risk factors, symptoms, and preventive strategies hampers the effectiveness of early …
Published in International Journal of Women's Health Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 19–24 Read article
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The Role of Digital Detox in Improving Mental Health
Abstract: This study examines digital detox—the deliberate limitation of screen exposure—and its influence on mental health. A survey of 30 participants indicated that reducing screen time by at least two hours daily resulted in a 30% improvement in sleep quality, a 25% decrease in stress levels, and a 20% enhancement in overall mood stability. Statistical analysis (p < 0.05) confirmed these results. Additionally, participants following a structured digital detox plan reported …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 15, Issue 2, 2025 Read article
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Assessing the Increasing Incidence of Prostate Cancer in Urban Delhi: Risk Factors, Early Detection, and Treatment Challenges
Abstract: Background: Prostate cancer has emerged as the second most prevalent cancer among men in India, with rapidly increasing incidence rates in urban areas like Delhi. This rise is attributed to urbanization, lifestyle changes (high-fat diets, tobacco use, sedentary behavior), increased life expectancy, and improved diagnostics. Despite its growing burden, low awareness, limited screening programs, and treatment barriers hinder early detection and effective management. This study examines the epidemiological trends, risk …
Published in International Journal of Oncological Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 21–28 Read article
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Factors Affecting Uptake of COVID-19 Vaccines Among Adults: A Cross Sectional Survey
Abstract: The COVID-19 vaccination started in phased manner in India, and it was first time when a digital platform was developed for vaccine site registration. People had skepticism about newly developed vaccines and had poor understanding of using digital platform for vaccination registration. It was one of the reasons for poor vaccination coverage in marginalized section of the society. The pandemic has also affected other healthcare services as people were worried …
Published in International Journal of Community Health Nursing And Practices · Vol. 1, Issue 2, 2023 Read article