Nano Trends – A Journal of Nano Technology & Its Applications Original Research
Enhancing Cancer Diagnosis: AI/ML Algorithms and Nanotechnology-Based Biosensors for Colorectal Cancer Screening
Abstract
Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide, and enhancing patient outcomes requires early identification. This study explores the potential of nanotechnology- enhanced biosensors and artificial intelligence/machine learning (AI/ML) algorithms to revolutionize colorectal cancer screening and diagnosis. Nanotechnology offers unique opportunities for the development of highly sensitive and specific biosensors capable of detecting cancer biomarkers at an early stage. By incorporating nanomaterials with exceptional optical, electrical, and catalytic properties, biosensors can achieve unprecedented levels of sensitivity and selectivity. Additionally, the integration of AI/ML algorithms with biosensor data can further enhance the diagnostic accuracy, enabling early detection and personalized treatment strategies. This study delves into the latest advancements in nanomaterial-based biosensors, AI/ML algorithms for cancer diagnosis, and their synergistic applications in colorectal cancer screening. It also discusses the challenges, future perspectives, and potential impact on improving patient care and reducing the burden of colorectal cancer.
Keywords
References (20)
- Center MM, Jemal A, Smith RA, Ward E. Worldwide Variations in Colorectal Cancer. CA: A Cancer Journal for Clinicians. 2009;59(6):366-378. doi:10.3322/caac.20038
- Eswaran U, Eswaran V, Sudharshan VB. Human like biosensor disease simulator, disease analyzer and drug delivery system. 2013 IEEE CONFERENCE ON INFORMATION AND COMMUNICATION TECHNOLOGIES. 2013:1033-1038. doi:10.1109/cict.2013.6558250
- Eswaran U, Madhavilatha M, Murthy J, Ganji Expert system design for disease detection using pattern recognition techniques. In: Arabnia HR, Mun Y, editors. Proceedings of the 2008 International Conference on Artificial Intelligence, ICAI 2008, July 14-17, 2008, Las Vegas, Nevada, USA, 2 Volumes (includes the 2008 International Conference on Machine Learning; Models, Technologies and Applications). Las Vegas (NV): CSREA Press; 2008. p. 902-6. Available from: https://dblp.org/rec/conf/icai/EswaranMMG08.bib.
- Madhavilatha M, Eswaran U, Ganji A proposal for design of hybrid multi-functional implantable biochip using bio-intelligent expert system. In: Arabnia HR, editor. Proceedings of the 2006 International Conference on Artificial Intelligence, ICAI 2006, Las Vegas, Nevada, USA, June 26-29, 2006, Volume 2. Las Vegas (NV): CSREA Press; 2006. p. 426-32. Available from: https://dblp.org/rec/conf/icai/MadhavilathaEG06.bib.
- Eswaran U, Ganji MR, Thakur MS. Microprocessor based biosensors for determination of toxins and pathogens in restricted areas of human intervention. In: Arabnia HR, editor. Proceedings of the International Conference on Artificial Intelligence, IC-AI '04, June 21-24, 2004, Las Vegas, Nevada, USA, Volume Las Vegas (NV): CSREA Press; 2004. p. 525. Available from: https://dblp.org/rec/conf/icai/EswaranGT04.bib.
- Lee J, Maji S, Lee H. Fabrication and integration of a low‐cost 3D printing‐based glucose biosensor for bioprinted liver‐on‐a‐chip. Biotechnology Journal. 2023;18(12). doi:10.1002/biot.202300154
- Min J, Baeumner AJ. Characterization and Optimization of Interdigitated Ultramicroelectrode Arrays as Electrochemical Biosensor Transducers. Electroanalysis. 2004;16(9):724-729. doi:10.1002/elan.200302872
- Eswaran V, Eswaran U, Eswaran V, Murali Revolutionizing healthcare: the application of image processing techniques. In: Khang A, editor. Medical robotics and AI-assisted diagnostics for a high- tech healthcare industry. Hershey (PA): IGI Global; 2024. p. 309-24.
- Acosta JN, Falcone GJ, Rajpurkar P, Topol EJ. Multimodal biomedical AI. Nature Medicine. 2022;28(9):1773-1784. doi:10.1038/s41591-022-01981-2
- Kim M, Kang D, Kim MS, Choe JC, Lee SH, Ahn JH, et al. Acute myocardial infarction prognosis prediction with reliable and interpretable artificial intelligence system. Journal of the American Medical Informatics Association. 2024;31(7):1540-1550. doi:10.1093/jamia/ocae114
- Chugh V, Basu A, Kaushik A, Manshu, Bhansali S, Basu AK. Employing nano-enabled artificial intelligence (AI)-based smart technologies for prediction, screening, and detection of cancer. Nanoscale. 2024;16(11):5458-5486. doi:10.1039/d3nr05648a
- Eswaran U, Khang A, Eswaran V. Applying Machine Learning for Medical Image Processing. Advances in Medical Technologies and Clinical Practice. 2023:137-154. doi:10.4018/979-8-3693-0876-9.ch009
- Brandalero M, Ali M, Le Jeune L, Hernandez HGM, Veleski M, da Silva B, et al. AITIA: Embedded AI Techniques for Embedded Industrial Applications. 2020 International Conference on Omni-layer Intelligent Systems (COINS). 2020:1-7. doi:10.1109/coins49042.2020.9191672
- Shrivastava S, Patel D, Gifford WM, Siegel S, Kalagnanam J. ThunderML: A Toolkit for Enabling AI/ML Models on Cloud for Industry 4.0. Lecture Notes in Computer Science. 2019:163-180. doi:10.1007/978-3-030-23499-7_11
- Eswaran U, Khang A. Augmented reality (AR) and virtual reality (VR) technologies in surgical operating In: Khang A, editor. AI and IoT technology and applications for smart healthcare systems. Boca Raton (FL): Auerbach Publications; 2024. p. 113-29.
- Eswaran U, Khang Artificial intelligence (AI)-aided computer vision (CV) in healthcare system. In: Khang A, Abdullayev V, Hrybiuk O, Shukla AK, editors. Computer vision and AI-integrated IoT technologies in the medical ecosystem. Boca Raton (FL): CRC Press; 2024. p. 125-37.
- Amann J, Blasimme A, Vayena E, Frey D, Madai VI; Precise4Q consortium. Explainability for artificial intelligence in healthcare: a multidisciplinary perspective. BMC Med Inform Decis Mak. 2020 Nov 30;20(1):310. DOI: 1186/s12911-020-01332-6. PubMed: 33256715; PMCID: PMC7706019.
- Eswaran U, Eswaran V, Murali K, Eswaran V. Healthcare smart sensors: applications, trends, and future In: Khang A, editor. Driving smart medical diagnosis through AI-powered technologies and applications. Hershey (PA): IGI Global; 2024. p. 24-48. doi:10.4018/979-8- 3693-3679-3.ch002.
- Markus AF, Kors JA, Rijnbeek PR. The role of explainability in creating trustworthy artificial intelligence for health care: A comprehensive survey of the terminology, design choices, and evaluation strategies. Journal of Biomedical Informatics. 2021;113:103655. doi:10.1016/j.jbi.2020.103655
- Eswaran U. Fortifying Cybersecurity in an Interconnected Telemedicine Ecosystem. Advances in Medical Technologies and Clinical Practice. 2024:30-60. doi:10.4018/979-8-3693-2141-6.ch002