cancer biomarkers
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Extracellular Vesicle-Based Liquid Biopsies: Decoding the Tumor Microenvironment for Precision Oncology
Abstract: The tumor microenvironment (TME) plays a pivotal role in cancer initiation, progression, and therapeutic response. Decoding the TME is, therefore, essential for advancing precision oncology. Extracellular vesicles (EVs), including exosomes and microvesicles, are nanoscale lipid bilayer particles secreted by tumor and stromal cells. They transport a wide range of bioactive molecules, such as DNA, RNA, proteins, lipids, and metabolites, which reflect the dynamic state of the TME. Recent advances in …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 43–62 Read article
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Enhancing Cancer Diagnosis: AI/ML Algorithms and Nanotechnology-Based Biosensors for Colorectal Cancer Screening
Abstract: Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide, and enhancing patient outcomes requires early identification. This study explores the potential of nanotechnology- enhanced biosensors and artificial intelligence/machine learning (AI/ML) algorithms to revolutionize colorectal cancer screening and diagnosis. Nanotechnology offers unique opportunities for the development of highly sensitive and specific biosensors capable of detecting cancer biomarkers at an early stage. By incorporating nanomaterials with exceptional optical, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 1, 2024 · pp. 16–28 Read article