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61 articles for “mass spectrometer”
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Synthesis and Characterization of m-Amino Pyridine Derivatives
Abstract: Background: The current study involves the synthesis and characterization of amino derivatives. In the current research study, a series of m-amino pyridine derivatives were synthesized using m-amino pyridine and carbonyl compounds and characterized further. The pyridine derivatives have shown to possess potent antibacterial, antifungal, antitumor, antimalarial, anti-inflammatory antidiabetic, antioxidant, anthelmintic, anticonvulsant, antituberculous and so many other properties. Method: The condensation reaction of m-amino pyridine and carbonyl derivatives with ethanol is …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 10, Issue 2, 2023 · pp. 1–6 Read article
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LCMS/MS Analysis of the Ethylacetate Extract of Securidaca longipedunculata Fresen (Polygalaceae) Stem Bark
Abstract: The present study aimed to identify some of the phytoconstituents of a fraction (fraction DDK-4) obtained from the column chromatography of the ethylacetate extract of Securidaca longipedunculata Fresen (Polygalaceae). Liquid Chromatography-Mass Spectrometry (LCMS/MS) analysis of fraction DDK-4 was conducted on a Waters Synapt G2 quadrupole time-of-flight mass spectrometer (Milford, MA, USA) using positive mode of ionization. The results showed that 1,7-dihydroxy-2,8-dimethoxy xanthone, 3-(1,3-benzodi-oxol-5-yl-4-morpholinyl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-1-propanone, 5,7-dihydroxy-6-methyl-3-(2’,4’-dihydroxybenzyl)-chroman-4-one, trans-O-methyl-grandmarin, dioctylamine, rhodioloside, punicic acid, echimidine, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 1, 2022 · pp. 39–47 Read article
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Formulation of Vancomycin Capsules and Characterization of Related Substances
Abstract: Aim of this research work was to develop vancomycin capsules and analysis of the related substances which was performed using HPLC and mass spectrometer. The impurities present in the formulation were identified and the two unknown impurities present at RRT about 0.65 and 2.10, were isolated, purified and characterized. The first impurity was found to be a polar substance and it was found to arise due to the amide cleavage …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 3, 2015 · pp. 42–51 Read article
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Characterization Of Senna Occidentalis (Link.) Seed Extract
Abstract: Senna occidentalis (L.) Link commonly known as "coffee senna" or majamfari/rai dore in Hausa is a plant with a long history of traditional and medicinal uses against diseases such as inflammation, pains, and diabetes. This study presents characterization of the bioactive compounds of the seed extracts. Physicochemical analysis of seed powder was carried out following standard procedures. Qualitative phyto-chemical contents were determined for the presence and absence of major metabolites. …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 3, 2024 · pp. 13–22 Read article
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Characterization of Synthesized Heterocyclic Oxadiazole Derivatives Using Mass, UV, IR, and NMR Spectroscopy, Among other Spectroscopic Techniques: Review
Abstract: The current study synthesized and assessed 3-heteroarylazo 4-hydroxy coumarin derivatives' initial antibacterial activities in vitro against four distinct pathogenic bacterial strains, including Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli, and Staphylococcus aureus. Ampicillin, a common medication, was used to compare each compound's antibacterial properties. UV, IR, 1H NMR, mass spectroscopy, and X-ray diffraction examinations were used to analyze the compounds. By using UV–vis spectra, the solute-chromic behavior of these compounds was …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 1, 2023 · pp. 28–33 Read article
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Investigations Into the Potential for Anthracene Decomposition of Novel Soil Bacterium, Pseudomonas putida P7
Abstract: Bioremediation of hazardous contaminants holds immense importance for the preservation of a clean and healthy environment. Conversely, the accumulation of toxicants can be mitigated with the assistance of microorganisms capable of breaking down these harmful substances into benign molecules. Anthracene is frequently used as a model molecule for studies on PAH pollution because it is found in many carcinogenic PAHs. Therefore, the hunt for new microorganisms with the ability to …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 29–44 Read article
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Extraction and Compound Analysis of Bauhinia acuminata: Soxhlet Method and Identification
Abstract: In the present study, the extraction and compound analysis of Bauhinia acuminata using the Soxhlet method, coupled with identification techniques, were conducted. Bauhinia acuminata L., a member of the Leguminosae (Fabaceae) family in the Caesalpinioideae subfamily, is a shrub usually reaching a height of around 3 m. It is native to tropical Southeast Asia and commonly found in the tropical regions of India and China. Primarily grown for ornamental purposes, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 18–23 Read article
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Synthesis, Characterization and Evaluation of Pyridine derivatives
Abstract: Schiff bases, a class of organic compounds, have garnered significant attention due to their diverse applications in various fields such as pharmaceuticals, materials science, and coordination chemistry. This study provides a comprehensive overview of the synthesis of Schiff bases amino pyridine derivatives and aromatic ketones along with their anti-microbial activity. Method: The synthesis of Schiff bases primarily involves the condensation reaction between a primary amine and a carbonyl compound (ketone) …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 2, 2024 · pp. 35–48 Read article
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Non-Enzymatic Glycation in Alzheimer’s and Parkinson’s Disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several neurodegenerative diseases, particularly Alzheimer’s disease (AD) and Parkinson’s disease (PD). The accumulation of AGEs can significantly alter protein structure, stability, and function, triggering a cascade of detrimental effects, including increased oxidative stress, heightened neuroinflammation, and the promotion …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 36–41 Read article
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Recent Advancements in High-Performance Liquid Chromatography: A Comparative Approach
Abstract: Modern separation science relies heavily on chromatography, which is used in all research institutes and pharmaceutical industries all around the globe. Of all the chromatography approaches, HPLC i.e. high performance liquid chromatography is the one that is most frequently used analytically. Recent improvements in chromatographic supports and liquid chromatography (LC) equipment have made rapid and incredibly effective separations possible. This summary emphasizes the key milestones and foundational advances in HPLC …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 40–48 Read article
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Production of n-Butanol from Biomass by Two Step Fermentation Process Using Staphylococcus Sciuri
Abstract: This study explores the sustainable production of n-butanol from wheat husk through a two-step bioconversion process. Wheat husk, an abundant agricultural residue, was first fermented into butyric acid using Bacillus subtilis. The resultant butyric acid was then converted into n-butanol using Staphylococcus sciuri. The process leverages biological fermentation to create value-added chemicals from lignocellulosic biomass, offering an eco-friendly alternative to petrochemical methods. Two steps fermentation process were carried to increase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 18–31 Read article
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An Efficient Synthesis of Some Novel Benzo Coumarin Derivatives Under Solvent Conditions from 2-acetyl-benzo[f]chromen-3-one
Abstract: The synthesis of the target compounds began with the preparation of 2-[3-dimethylamino[acryloyl-3H-benzo[f]chromen-3-one. This intermediate was obtained through the reaction of 2-acetylbenzo[f]coumarin-3-one with N,N-dimethylformamide dimethyl acetal [DMFDMA[ under reflux conditions in xylene. The enaminone thus formed was subsequently reacted with 6-aminothiouracil in acetic acid, leading to the formation of 2-thioxo-2,3-dihydro-1H-pyrido[2,3-d]pyrimidin-4-one. This compound served as a pivotal intermediate for the synthesis of a series of pyridotriazolopyrimidinones. These derivatives were synthesized by reacting …
Published in International Journal of Cheminformatics · Vol. 2, Issue 2, 2024 · pp. 33–46 Read article
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Design, Synthesis, and Spectroscopic Elucidation of 3-Methyl-1-Phenylpyrazol-5-One: A Cheminformatics-Aided Approach to Heterocyclic Drug Scaffolds
Abstract: Pyrazolone, a notable heterocyclic compound, has drawn increasing interest due to its broad pharmacological profile and structural versatility. The synthesis, characterisation, and biological assessment of new pyrazolone derivatives are examined in this work. A comprehensive review of existing synthetic strategies is presented, emphasizing green and efficient methodologies. Novel derivatives were synthesized using varied starting materials and catalytic systems, followed by structural confirmation through spectroscopic analyses, including NMR, IR, and mass …
Published in International Journal of Cheminformatics · Vol. 3, Issue 1, 2025 · pp. 29–40 Read article
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Advances in Analytical Chemistry Research Methodology: Trends and Applications
Abstract: Analytical chemistry is critical to scientific study because it allows for the accurate identification, measurement, and characterization of chemical compounds. Recent advances in methodology have improved accuracy, sensitivity, and efficiency, with techniques such as High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Mass Spectrometry (MS), and Nuclear Magnetic Resonance (NMR) spectroscopy transforming analytical procedures. The combination of Artificial Intelligence (AI) and Machine Learning (ML) has enhanced data processing, pattern recognition, and …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 2, 2025 · pp. 10–18 Read article
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A Comprehensive Review of Metabolite
Abstract: Metabolites, tiny chemicals, are essential to physiology, signalling, and biological function. This extensive review classifies metabolites into primary and secondary categories by biological relevance. Alkaloids, flavonoids, and terpenoids contribute to ecological interactions and defence systems, while amino acids, nucleotides, and carbohydrates directly affect development and cellular function. The article examines metabolic pathways, mass spectrometry, NMR, and metabolomics, a growing field. Metabolites play a crucial role in various scientific and practical …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Isolation and Characterization of Glucuronide Compound from Luffa Tuberosa (Roxb.) for Potential Applications in Polymer Chemistry
Abstract: This study explores the isolation process of glucuronide compounds from Luffa tuberosa (Roxb.) using an efficient and cost-effective method. The extracted compound, Gypsogenin-3β-O-β-D-Methyl glucuronide, is characterized using spectroscopic techniques such as IR, NMR, and Mass Spectrometry. The polymeric nature of glucuronide-based compounds and their potential applications in polymer and composite materials are discussed. The findings highlight the suitability of glucuronide derivatives in biomedical, pharmaceutical, and polymeric drug delivery systems. Additionally, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 566–572 Read article
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Heavy Metal Exposure in Industrial Workers of Punjab
Abstract: Background: Particularly for those in sectors such textiles, metallurgy, and electronics, heavy metal exposure in industrial environments is a major health issue. A range of negative health effects can result from metal exposure including lead (Pb), cadmium (Cd), chromium (Cr), arsenic (As), and nickel (Ni), including neurological, pulmonary, and renal ones. There is little information available on the degree of heavy metal exposure industrial workers in Punjab, India experience. Objective: …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–7 Read article
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Comparative Study of Bioactive Phytochemicals from Hexane Extract of Two Amaranthaceae Leafy Vegetables by GC-MS Method
Abstract: Amaranthus tricolor Linn and Amaranthus viridis Linn, belonging to the Amaranthaceae family, are popularly consumed leafy vegetables in India and many other countries globally. The bioactive components of Hexane extract from these two plants have been analysed using gas chromatography-mass spectrometry (GC–MS) technique. According to analysis, both species contain a total of nineteen important chemicals. Of these, ten were found in A. tricolour L. and nine in A. viridis L. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 7–17 Read article
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Guanidine as a Starting Material for Preparing a Scale Inhibitor
Abstract: Oilfield scale inhibition, which can obstruct fluid flow in pipelines, valves, and pumps during oil production and processing, is critical for preventing scale formation. Effective scale inhibitors (SIs) minimize downtime and enhance productivity by preventing the build-up of insoluble crystals in water systems. In oil processing, scale formation results from the precipitation of salts due to incompatible aqueous phases, leading to equipment blockage. Phosphonates are highly effective chelating agents for …
Published in Journal of Petroleum Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 15–28 Read article
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Reactivity of Monochlorotetrakis2-Isopropylphenoxoniobium(V), [NbCl(OC6H4CH(CH3)2-2)4] towards Chelating Ligands
Abstract: The niobium(V) complexes with the formula [NbCl(OC₆H₄CH(CH₃)₂-2)₄] were successfully synthesized in high yields through the reaction of niobium pentachloride with four equivalent amounts of 2-isopropylphenol in carbon tetrachloride. The synthesized complexes were characterized and confirmed by elemental analysis, molar conductance measurements, infrared (IR) spectroscopy, ^1H and ^13C NMR spectroscopy, as well as mass spectrometric analysis. The spectroscopic studies have shown these to exhibit dimeric structures bridging through isopropylphenoxo groups. The …
Published in International Journal of Minerals · Vol. 3, Issue 1, 2026 · pp. 37–45 Read article