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Research & Reviews: A Journal of Drug Formulation, Development and Production

Synthesis and Characterization of m-Amino Pyridine Derivatives

  1. ALKA TYAGI
  2. Tarmale Pooja
  3. Tiwari Sumit
  4. Turerao Mallika
  5. Verma Nisha
  6. Vishwakarma Radhika

Abstract

Background: The current study involves the synthesis and characterization of amino derivatives. In the current research study, a series of m-amino pyridine derivatives were synthesized using m-amino pyridine and carbonyl compounds and characterized further. The pyridine derivatives have shown to possess potent antibacterial, antifungal, antitumor, antimalarial, anti-inflammatory antidiabetic, antioxidant, anthelmintic, anticonvulsant, antituberculous and so many other properties. Method: The condensation reaction of m-amino pyridine and carbonyl derivatives with ethanol is the method used to produce m-amino pyridine derivatives. We synthesized six novel m-amino pyridine compounds for this study. The synthesized derivatives were analyzed using IR, 1HNMR, and mass spectrometry, followed by elemental analysis. Conclusion: m-Amino pyridine derivatives were analyzed using IR, NMR, and mass spectrometry, followed by elemental analysis. All the physical parameters of synthesized compounds were attained like melting point,  Rf value and % yield etc. The research's findings are important for future studies. The synthesized compounds can be further evaluated for antibacterial, antifungal, antitumor, antimalarial, anti-inflammatory and antidiabetic activities.

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