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43 articles for “Tuberculous”
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Oxadiazole Derivatives Recent Progress in Synthesis and Bioactivity
Abstract: Over the past few decades, significant advancements have been made in the development of heterocyclic derivatives, leading to the production of numerous novel agents, both synthetic and natural in origin. Because of its numerous biological properties, including antibacterial, antiviral, and antifungal properties, thiazole is a special five-membered heterocyclic motif among heterocyclic compounds. It is utilized as a fundamental building block in many pharmaceutically significant compounds. To the best of our …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 15, Issue 1, 2024 · pp. 62–67 Read article
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A Literature Survey on Biological Activities of Thiazolidine Derivatives
Abstract: Hetercyclic compounds play a vital role in both chemical and life sciences. Among them ,thiazolidinone represent a significant class, characterized by a five- membered saturated ring containing both sulfur and nitrogen atoms. Structurally, thiazolidinones are derived from thiazole, with sulfur position at the 1-position, nitrogen at the 3-position , and a carbonyl group typically located at the 2-, 4-, or 5- position are possible, though structural and functional diversity is …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 16–21 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Innovative Vaccine Technologies: Current Landscape and Future Prospects in Preventive Medicine
Abstract: This review article presents a comprehensive analysis of recent advancements and emerging trends in vaccine development, offering insights into the dynamic landscape of preventive medicine. Delving into a spectrum of infectious diseases, including influenza, HIV/AIDS, malaria, tuberculosis, respiratory syncytial virus (RSV), Group B Streptococcus (GBS), norovirus, and chikungunya, the review highlights innovative approaches and breakthroughs in vaccine technology. It explores efforts to develop universal influenza vaccines, long-awaited HIV vaccines, and …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 07–15 Read article
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Breakthroughs in Biotechnology for the Regulation of Infectious Diseases
Abstract: Infectious diseases have a heavy impact on both public health and the world’s economies. In most diseases, antibiotic resistance has become widespread over time. A variety of diseases comprising pneumonia, tuberculosis, and gonorrhea go through the same evolutionary processes, which include the formation of drug-resistant pathogens in response to selection pressure from medications and their potential extinction when drug use is ceased. Since the occurrence of drug resistance in serious …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 1–25 Read article
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Survey in Hydrazine and its Preparation, Reactions, and Their Applications
Abstract: This review concerned with hydrazine derivatives; Hydrazine is an important chemical compound used in jet engine and rocket fuel. Therefore, the European Union prohibits its sales to the developing world at 100% concentration and only permits its sales at 20-25% concentration. It is also used in industry to produce chemicals for textiles, agriculture, photographic development materials, and blowing agents used in the manufacture of foam rubber. It is also used …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 27–34 Read article
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Overview On Lauha Rasayana W.S.R. To Rasayogasagar
Abstract: Ayurved is the ancient science which addresses disorders with the natural pharmaceuticals, including those derived from animals, plants, minerals and metals. Rasashastra is a pharmaceutical branch of Ayurved medicine, which developed in mediaeval period and focuses on therapeutic use of metals and minerals. Treatment with using of this metals, minerals, gemstones, animal product and herbal ingredients is known as Rasachikitsa. The key objective of Rasachikitsa is to deliver high-quality, safe …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 11–16 Read article
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Clinical experience with Ayurvedic Treatment in Case of Rheumatoid Arthritis – Ayurvedic review and Case study
Abstract: Rheumatoid arthritis is the most found inflammatory auto immune disease with unknown etiology. Many clinical features and treatment strategies of RA are associated with multiple joint diseases. The clinical phenotype of Rhematoid arthritis is a symmetrical, deformed polyarthritis of small and large joints, which is often associated with features of the disease. The treatment typically involves ongoing management with periods of worsening symptoms followed by periods of improvement. Features of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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Effectiveness of Structured Teaching on Immunization Knowledge and Attitude Among Mothers of Children Under-5 years of Age at Bal Mahila Chikitsalaya, Lucknow
Abstract: This section offers a thorough overview of the study's background, explaining the significance of vaccination, the variables affecting vaccination coverage, the role mothers play in the decision-making process regarding vaccinations, and the necessity of focused interventions to improve immunization uptake among children under five. As a fundamental component of preventive healthcare, immunization shields both individuals and communities from a variety of infectious diseases. In order to comprehensively assess changes in …
Published in International Journal of Children · Vol. 1, Issue 1, 2024 · pp. 5–22 Read article
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Management of Steroid Induced Diabetes with Unani Medicine: A Case Report
Abstract: Background: Glucocorticoids (GC), such as prednisolone, are commonly used for their anti-inflammatory and immunosuppressive properties. However, chronic GC use can lead to adverse effects, including diabetes. This case study evaluates the efficacy of Arq Afsanteen, an Unani compound drug, in managing GC-induced diabetes. A 50-year-old man with a family history of type 2 diabetes and a history of partial gastrectomy was diagnosed with sarcoid tuberculosis and began treatment with ATT …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 49–53 Read article
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Social Determinant in Health : Epidemiological study of communicable diseases, Demography and Mortality rate.
Abstract: Introduction: Social Determinants of Health (SDH) significantly influence the spread and prevalence of communicable diseases. Factors such as poverty, income inequality, healthcare access, education, employment, location, and social connections shape disease transmission within populations. Additional factors like age, gender, migration, and urbanization further explain the relationship between SDH and public health. Mortality rates, including life expectancy, infant mortality, and access to clean water and sanitation, are deeply affected by these …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 41–56 Read article
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HIV/TB Co-Ordination Program - An Integration in Highly Epidemic Provinces
Abstract: Tuberculosis is the commonest co-infection among PLHA (HIV/AIDS). An appropriate measure for controlling TB spread in community of high TB/HIV burden state that requires intervention strategies against this dual epidemic which include intensified case finding at ART centers, involvement of health care delivery system, and Non-Government Organizations for early detection of TB and HIV, counselling and support, provision of daily patient’s weight band-wise FDD, ATT for TB, cotrimoxazole preventive/ prophylaxis …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 20–26 Read article
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Synthesis, Characterization, Antibacterial Evaluation and Study of Organic Separation Behavior for Five Membered Ring for Pyridine Derivatives
Abstract: Imidazoles can be prepared by condensation between amines and various aldehydes and ketones. Imidazole derivatives are important compounds due to their broad biological activity and pharmacological properties, such as antifungal, antioxidant, cytotoxic, anti-inflammatory, analgesic, anti-YFV (yellow fever virus), anti-tuberculosis, and antimicrobial activity. In recent years, many studies have been conducted on the preparation of biological imidazole derivatives, especially derivatives linked to heterogeneous rings containing nitrogen or any other donor atom. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 106–121 Read article
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Formation, Organic Investigation, Fluorescence Study of New Cyclic Derivatives of Thiophane-Triazole Compounds
Abstract: Azo compounds are used as intermediates in the preparation of many well-known and diverse organic derivatives. Cyclical or related azo derivatives, such as triazoles and thiophenes, possess useful applications in medicinal and pharmaceutical chemistry. Thiophene compounds and their derivatives have demonstrated a variety of biological activities, including antibacterial, antifungal, anti-tuberculosis, anti-inflammatory, analgesic, sedative, and hypnotic properties, immunosuppressive, and antihypertensive properties. Furthermore, thiophene derivatives can be used in the treatment of …
Published in Emerging Trends in Chemical Engineering · Vol. 12, Issue 3, 2025 · pp. 1–13 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: Pathogens have evolved a wide repertoire of virulence strategies that allow them to invade host tissues, establish infection, and circumvent immune responses. From the initial steps of adhesion and colonization to complex molecular mimicry, antigenic variation, and immunomodulation, pathogens display remarkable adaptability. While traditional research has emphasized host cell entry and toxin production, emerging evidence highlights subtler and more dynamic strategies such as manipulation of host signaling pathways, subversion of …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Host-Pathogen Coevolution: Implications for Immune Evasion and Pathogen Fitness
Abstract: The interaction between hosts and pathogens represents a continuous evolutionary struggle, shaping both microbial virulence and host immunity. Pathogens employ diverse strategies to evade immune surveillance, ranging from antigenic variation and molecular mimicry to hijacking of host immune checkpoints. Simultaneously, hosts refine innate and adaptive immune mechanisms to counteract infection and limit damage. This reciprocal adaptation, known as host–pathogen coevolution, influences pathogen persistence, transmission, and fitness, while also sculpting immune …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 · pp. 6–10 Read article
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Mid-Year Epidemiological Profile of COVID-19 Posi ve Cases in Rajasthan, India
Abstract: Background: COVID-19, caused by SARS-CoV-2, has posed persistent public health challenges globally since its emergence in late 2019. India, through enhanced surveillance and vaccina on, has seen a progressive decline in case burden. Despite improvements, localized surges and emerging variants necessitate con nuous monitoring. Rajasthan, with its urban-rural health dispari es, experienced a modest resurgence of cases in early 2025, raising concerns about exis ng immunity gaps and health system …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Understanding Airborne Pathogens: Pathways, Risks, and Control Strategies
Abstract: Airborne transmission is the transfer of germs through the air, mostly by respiratory droplets and aerosols that come out when you cough, sneeze, talk, or breathe. These particles can stay in the air for a long time and move a long way, especially in small or poorly ventilated places. Mycobacterium tuberculosis, measles virus, varicella-zoster virus (chickenpox), influenza virus, and more recently, SARS-CoV-2 are all infections that can be spread through …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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5-Methyl-2-phenyl-2,4-dihydro-3H-pyrazol-4-one: Synthesis and Reactions
Abstract: The presence of the five-member pyrazole nucleus in different structures leads to a large diversity in its applications. In almost every research study, the pyrazole derivatives biological importance faces a competitive challenge in areas of technology, medicine and agriculture. This reflects the description of these derivatives as antibacterial, antifungal, anticancer, antidepressant, anti-inflammatory, anti-tuberculosis, antioxidant as well as antiviral agents. In our review, we will discuss and show the highlights of …
Published in Journal of Modern Chemistry & Chemical Technology · Vol. 16, Issue 3, 2025 Read article
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article