Research and Reviews : A Journal of Immunology Original Research
Mid-Year Epidemiological Profile of COVID-19 Posi ve Cases in Rajasthan, India
Abstract
Background: COVID-19, caused by SARS-CoV-2, has posed persistent public health challenges globally since its emergence in late 2019. India, through enhanced surveillance and vaccina on, has seen a progressive decline in case burden. Despite improvements, localized surges and emerging variants necessitate con nuous monitoring. Rajasthan, with its urban-rural health dispari es, experienced a modest resurgence of cases in early 2025, raising concerns about exis ng immunity gaps and health system stress. This study aims to describe the epidemiology of COVID-19 posi ve cases in Rajasthan during January to June 2025 and assess trends in hospitaliza on, mortality, and comorbidi es.
Method: A cross-sec onal study design was used. Data from January to June 2025 were obtained from IDSP, hospitals, and tes ng laboratories across Rajasthan. Variables included age, sex, loca on, diagnosis date, hospitaliza on, comorbidity, and outcomes. Data were cleaned and analyzed using descrip ve sta s cs. Geospa al and me-trend analyses were conducted using Excel. Ethical permissions were secured, with no iden fiable pa ent data used.
Results: A total of 427 cases were reported, with 66% from Jaipur. Median age was 44 years; 79.9% resided in urban areas; and 57% were male. Hospitaliza on was required for 15% of cases, primarily at ter ary centers. Comorbidi es were present in 11.7% of cases, with diabetes and hypertension most common. Two deaths were reported (CFR = 0.46%) one in a 26-yearold with tuberculosis and another in a 52-year-old without known comorbidi es. A significant case surge occurred in June, accompanied by increased tes ng rates.
Conclusion: The resurgence of COVID-19 in Rajasthan during mid-2025, par cularly in urban hubs like Jaipur, highlights the need for sustained surveillance, preparedness, and integra on of NCD and infec ous disease management. The demographic and clinical pa erns observed emphasize the ongoing risk to working-age adults and the necessity for localized public health strategies
Keywords
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