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International Journal of Cheminformatics Review Article

A Literature Survey on Biological Activities of Thiazolidine Derivatives

  1. Vijaiyalakshmi R Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi
  2. Anbazhagan S Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi
  3. Subasri B Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi
  4. Divya J Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi
  5. Madeshwaran G Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi
  6. Eniyan M Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi
  7. Surya Prakash k Department of Pharmacy, Surya School of Pharmacy, Surya Group of Institution, Vikravandi

Abstract

Hetercyclic compounds play a vital role in both chemical and life sciences. Among them ,thiazolidinone represent a significant class, characterized by a five- membered saturated ring containing both sulfur and nitrogen atoms. Structurally, thiazolidinones are derived from thiazole, with sulfur position at the 1-position, nitrogen at the 3-position , and a carbonyl group typically located at the 2-, 4-, or 5- position are possible, though structural and functional diversity is most stronghly influenced by the group attached at the 2-position carbon 4- Thiazolidinones , in particular , are derivatives of thiazolidine featuring a carbonyl group in thiazolidinones is generally unreactive , its interaction with Lawessons reagent can yeild corresponding 4-thione derivatives . The presence of hetero atom such as nitrogen , sulfur, and oxygen contribute to the broad biological activity many heterocyclic compounds.

Keywords

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