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161 articles for “Therapeutic Actions”
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A Review on Pharmacognostic Profile of Ajuga reptans
Abstract: The present review was aimed to collect the pharmacognostic information about the Ajuga reptans, a flowering plant species of Lamiaceae family. The generic Greek name ‘Ajuga’ means “without yolk” and species ‘reptans’ means “creeping”. It is known by alternative common names including bugleweed, common bugle and carpetweed. Bugleweed is a native of Europe and widely distributed throughout New Zealand, North America and Venezuela. It is cultivated as an ornamental plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 7, Issue 1, 2020 · pp. 9–18 Read article
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Clinical Applications and Mechanism of Leech Therapy from the Perspective of Unani and Conventional Medicine: A Review
Abstract: Leech therapy is a kind of bloodletting that involves using leeches to remove a significant volume of blood from the body. Leeches are hermaphrodites, annelid worms that feed on blood and have a noticeable capacity to expand or contract. Hirudinaria granulosa is a type of Indian leech that has therapeutic qualities. Leech therapy operates on the tenets of Imala-i-Mawād (Diversion of morbid matter) and Tanqiya-e- Mawād (Evacuation of Morbid matter). …
Published in Research & Reviews : Journal of Herbal Science · Vol. 12, Issue 3, 2023 · pp. 7–12 Read article
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Effectiveness of Habb-e-Suranjan and Roghan-e-Farfiyun in the Management of Waja-ul-Rukba (Knee Pain): A Review
Abstract: Introduction: Knee osteoarthritis is a painful condition that represents the degeneration of the cartilage and osteophyte formation in the knee joint, which affects millions of people worldwide. According to the Unani claimed text, accumulation of “madda” (substance) in joints, which is neither absorbed nor expelled, is due to the absence of Quawwat-e-Jazibah (power of absorption) and Quawwat-e-dafia (power of expulsion). Unani medicine presents a promising approach for managing knee osteoarthritis …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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A Review On Wonder Plant Aloe Vera
Abstract: For millennia, people have utilized and appreciated the health, aesthetic, therapeutic, and skin- care benefits of aloe vera plants. Aloe is a plant that grows in dry regions of Africa, Asia, Europe, and America. It has approximately 300 species. Aloe barbadensis miller is the botanical name of aloe vera. It is a perennial, xerophytic, succulent, shrubby or arborescent plant with pea-green hue that is a member of the Asphodelaceae (Liliaceae) …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 1, 2024 · pp. 1–9 Read article
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Protective Effects Of Curcumin Against Osteoporosis And Its Molecular Mechanism
Abstract: One of the most prevalent metabolic disorders is osteoporosis (OP), which primarily affects postmenopausal women and the elderly. It is often associated with gradual loss of bone density, ongoing destruction of bone microstructure, and increased risk of osteoporosis. Pharmacotherapy is the primary approach for treating and preventing osteoporosis. However, persistent medication therapy invariably results in drug responses and particular adverse effects. Therefore, scientists continue to search for new monomeric compounds …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 1, 2024 · pp. 16–23 Read article
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Plant-Derived Psychotropic Agents Targeting Neurotransmitter Systems: Pharmacognostic Evidence, Mechanisms, and Clinical Relevance
Abstract: Psychiatric health problems are also a large burden on global health and existing psychotropic drugs may be restricted by relative effectiveness, side effects, and inadequate long-term tolerability. Plant- based psychotropic agents have subsequently been the focus of interest in the form of complementary or alternative therapies. This review outlines the pharmacognostic, mechanisms of action and therapeutic importance of plant-based psychotropic agents against central neurotransmitter systems. The traditional medicinal practices give …
Published in International Journal of Brain Sciences · Vol. 3, Issue 1, 2026 · pp. 34–42 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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A Comprehensive Review of Therapeutic and Pharmacological Potential of Karafs (Apium graveolens)
Abstract: The history of the medicinal properties of plants and their use in various ailments is as old as the history of mankind. Karafs (Apium graveolens) is one of the important plants among them, belonging to the family Apiaceae/Umbelliferae. Its use in various ailments has been documented in Unani classical literature in detail. Every part of Karafs possesses wonderful medicinal properties. A series of studies conducted to evaluate its medicinal uses …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Pharmacokinetic and Pharmacodynamic Studies of Black Seed Derived Compound
Abstract: Black seed (Nigella sativa) has been celebrated for centuries for its remarkable therapeutic properties. Among its bioactive compounds, thymoquinone (TQ) has gained significant attention in pharmacological research due to its diverse health benefits. This review delves into the pharmacokinetic (PK) and pharmacodynamic (PD) properties of black seed compounds, with a particular emphasis on TQ, the most extensively studied component. The PK of TQ includes the parameters of absorption, distribution, metabolism, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 1, 2025 · pp. 36–43 Read article
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Ocular Inserts: An Overview
Abstract: Ocular inserts are sterile preparations which are to be placed into cul-de-sac or conjuctival sac. The major aim of ocular insert is to maintain a therapeutic level at the site of action for prolonged period of time. The therapeutic efficacy of an ocular drug can be greatly improved by prolonging its contact with the corneal surface. Ocular insert gives several advantages like increased ocular residence time, drug release at a …
Published in Trends in Drug Delivery · Vol. 4, Issue 2, 2017 · pp. 20–22 Read article
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FDA Drug Approvals 2024: A Comprehensive Review
Abstract: The year 2024 has been pivotal for the pharmaceutical industry, with the U.S. Food and Drug Administration (FDA) granting approval to a diverse array of new drugs. These approvals highlight significant strides in therapeutic innovation, targeting a spectrum of diseases from rare genetic disorders to prevalent chronic conditions. This article provides a detailed examination of the FDA-approved drugs of 2024, focusing on their therapeutic indications, mechanisms of action, and the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 28–46 Read article
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RNA- Based Drug Delivery, Current Advances, Pharmaceutical Applications, and Future Perspectives
Abstract: RNA-based therapeutics have emerged as a transformative approach in modern medicine due to their ability to regulate gene expression with high specificity and precision. Advances in molecular biology, RNA chemistry, and nanotechnology have accelerated the development of diverse RNA modalities, including messenger RNA (mRNA), small interfering RNA (siRNA), microRNA (miRNA), antisense oligonucleotides (ASOs), and RNA aptamers. These therapeutics offer promising strategies for the treatment of cancer, genetic disorders, infectious diseases, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 · pp. 27–41 Read article
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A Critical Appraisal on Phytochemical Constituents and Therapeutic Effect of Yashtimadhu (Glycyrrhiza glabra)
Abstract: In present era, traditional medicines are getting more attention worldwide. Herbal medicines are one among them with great therapeutic significance and potential actions. Glycyrrhiza glabra is one of the important and widely used classical herbal medicinal plants with vast clinical action. Glycyrrhiza glabra Linn. Commonly known as Liquorice, sweet wood, Mulahatti and Yashtimadhu. It has key activities from getting rid of simple cough, eye troubles to curing asthma, bronchitis, abdominal …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 6, Issue 3, 2017 · pp. 6–10 Read article
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Unlocking the Healing Powers of Aṣl Khāliṣ (Honey): Exploring Its Functional and Therapeutic Potential
Abstract: Aṣl Khāliṣ (honey) as a natural product has grabbed the attention of researchers as a reciprocal and indispensable remedy. Honey has been used to heal both internal and external ailments for much longer than medicine has existed. Unani scholars have mentioned its action in classical literature as a nutritional agent, as well as a natural food supplement with therapeutic antibacterial, anti-inflammatory, cleansing, deobstruent, lithotryptic, and wound-healing properties. According to contemporary …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 3, 2025 · pp. 17–23 Read article
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Critical Analysis on Action of Basti: A review
Abstract: Introduction: Amongst PanchaKarma (Five basic therapeutic procedures in ayurvedic medicine), Basti is considered to be the most powerful tool for treatment. The above statement could be more easily understood with the statement of Acharya Charakaa, that the Basti is the best tool to alleviate the Vata Dosha which is the most powerful Dosha (one of the three basic element deciding health). Some of the ancient researchers have quoted importance of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 9, Issue 03, 2022 · pp. 32–36 Read article
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article
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Acetaminophen: Current Understanding and Future Directions in Pharmacology
Abstract: In this review, acetaminophen is described as one of the most widely used analgesic and antipyretic medications worldwide due to its effectiveness and reduced gastrointestinal toxicity compared with traditional NSAIDs. Its precise mode of action is still unclear despite widespread therapeutic use. Acetaminophen has little peripheral anti-inflammatory effect and largely acts within the central nervous system, in contrast to NSAIDs, which mainly block peripheral cyclooxygenase (COX) enzymes and lower inflammation. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 Read article
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Modulation of Receptor Proteins: A Recent Paradigm in Drug Discovery and Target
Abstract: The main aim in drug discovery is to design different ligands those work on specific drug targets. However, various effective drugs work through the modulation of many proteins than single target. Advancement in system biology are establishing a phenotypic strength and a network structure, which suggests that, the excellent selective compounds may be performed less than desired clinical efficacy in comparison to multi-target drugs. In this new appreciation of the …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 1, 2018 · pp. 14–24 Read article