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96 articles for “Lymph”
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Cure Fraction Estimation for Traumatic Lumbar Puncture in Patients with Acute Lymphoblastic Leukemia
Abstract: The foremost aim of this research was to estimate the proportion of long-term survivors for traumatic and bloody lumbar puncture in patients suffering from acute lymphoblastic leukemia (ALL). To decide the resonance point of platelet for predicting traumatic event the receiver operating characteristics curve was used. Logistic regression and Cox proportional hazard regression was used to detect risk factors for the traumatic event and any relapse, respectively. To appraise the …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 3, 2018 · pp. 12–21 Read article
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Incidence of Scrofula in Enlarged Neck Nodes
Abstract: To determine the incidence of scrofula (tubercular lymphadenitis) in enlarged neck nodes, prospective study is carried out in the Department of General Surgery, NIMS Medical College, Jaipur for three years from June 2011 to May 2014. The study included a group of 130 patients with cervical lymphadenopathy. All patients were clinically examined and investigated thoroughly. CBC, ESR, X-ray chest and Montoux’s test were performed. Fine Needle Aspiration Cytology (FNAC) and …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 3, 2014 · pp. 5–8 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Exploring Abies grandis phytocompounds potential by in silico analysis targeting on the 5P9J Protein
Abstract: Blood Cancer, also popular with name ‘Hematologic cancer’ have variety of types: Leukaemia, Lymphoma, Myeloma, uncontrolled multiplication of blood cells mainly affecting to bone marrow and blood cells (White Blood Cells). Lymphoma, originating from lymphatic system resulted in uncontrolled growth and instead of normal apoptosis development of tumor. Myeloma, uncontrolled formation of malignant plasma cells leads disrupting production of healthy blood cells. This situation creates variety of diseases like anaemia, …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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Recovery of Voice after Surgical Intervention in a Patient Suffering from Acquired Aphonia: A Case Study
Abstract: Aphonia is an inability to produce voice. There are number of causes of aphonia. These causes may either lie within vocal cords or on the nerves supplying the muscles of larynx which are responsible to produce voice. Among them, main cause is trauma or compression to recurrent laryngeal nerve or external laryngeal nerve that results in disturbed muscular activity of vocal cords. This case study is about the recovery and …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 1, 2020 · pp. 29–32 Read article
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Clinical Significance of Immune Cells and T-cell Subsets in Lung Cancer
Abstract: Objectives: The aim of the study was to determine the clinical usefulness of pretreatment hematological parameters including neutrophils, lymphocytes, monocytes and immune T-cell subsets as well as calculated coefficients such as neutrophils-to-lymphocytes ratio(NLR),monocytes-to-lymphocytes ratio(MLR) and platelets-to-lymphocyte ratio(PLR)in patients with lung cancer. Materials and Methods: A total of 102 patients with lung cancer were prospectively analyzed. T-cell subsets were assessed by flow cytometry method. Peripheral blood was collected from 25 healthy …
Published in Research and Reviews : A Journal of Immunology · Vol. 9, Issue 2, 2019 · pp. 14–29 Read article
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Hairy Cell Leukemia: A Morphological Dilemma in Case of Low Peripheral Blood Hairy Cell Count
Abstract: Hairy cell leukemia (HCL) is a lympho-proliferative neoplasm of mature B cells with an indolent course, representing 2 to 3% of all leukemias. It clinically presents as bicytopenia and splenomegaly. We here present a case report where peripheral blood smear showed few lymphoid cells with hairy projections. A suspicion of hairy cell leukemia was given which was confirmed later on bone marrow aspiration and biopsy followed by flow cytometry which …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 18–21 Read article
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Pharmacoinformatic Based Screening Of Phytocompound Epigallocatechin Gallate To Identify As A Potential Bcl-2 Inhibitor
Abstract: Objectives: The B-cell lymphoma-2 (Bcl-2) is a protein that is particularly though to be involved in preventing apoptosis. Bcl-2 family members also essential for cancer survival, and its over expression has been linked to tumor genesis, development and resistance to anticancer treatments. The Bcl-2 family of members that inhibit apoptosis is a promising target for the creation of anticancer drugs. Methods: The study was based on computational approach using different …
Published in International Journal of Bioinformatics and Computational Biology Read article
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A Narrative Review on Tuberculosis Disease Transmission, Treatment, Prevention, Emergency Care, and Vaccine Allocation in Second Highest Populated Country (India)
Abstract: Tuberculosis, an airborne illness caused by Mycobacterium tuberculosis, is a highly contagious disease primarily impacting the lungs, though it can also affect other body parts, excluding hair and nails. There are two main types of tuberculosis: pulmonary tuberculosis (PTB), which targets the lungs, and extrapulmonary tuberculosis (EPTB), which involves other areas such as lymph nodes, bones, joints, and the nervous system. The theme for World Tuberculosis Day in 2024 is …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 7–13 Read article
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Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in Philadelphia Chromosome-Positive Leukemias: An Overview of Mechanisms, Clinical Implications, and Management Strategies
Abstract: Tyrosine kinase inhibitors have greatly enhanced the outlook for individuals diagnosed with Philadelphia chromosome-positive leukemias, including chronic myeloid leukemia and acute lymphoblastic leukemia. However, these therapeutic agents are associated with Cardiotoxicities and can manifest as left ventricular dysfunction, which may progress to heart failure, along with electrocardiographic abnormalities, dysrhythmias, hypertension, myocardial ischemia, and thromboembolic events. The unclear frequency of drug-induced cardiovascular complications, coupled with uncertainties regarding their reversibility and long-term …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 18–24 Read article
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Dasatinib Induced Pulmonary Hypertension
Abstract: Dasatinib (Das) is a second-generation tyrosine kinase inhibitor that is used in the treatment of chronic myelogenous leukemia (CML) in patients who are resistant or intolerant to imatinib, as well as in Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL) patients. Dasatinib-induced pulmonary arterial hypertension (PAH) is a known but rare adverse effect of dasatinib and is grouped under Group-1 PAH. The mechanism of PAH development is not fully known, but …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 92–95 Read article
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Prevalence and Risk Factors of Neglected Tropical Diseases Among Women and Children in Rural Liberia: A Regional Perspective
Abstract: Neglected Tropical Diseases (NTDs) remain a critical public health challenge in Liberia, disproportionately affecting women and children in rural regions due to systemic inequities in water, sanitation, and healthcare access. This cross-sectional study assessed the prevalence and risk factors of NTDs among 1,000 participants (600 children above 15 years and 400 women aged 15–49) in rural Liberia using stratified and cluster sampling. Laboratory diagnostics, including Kato-Katz stool analysis, urine filtration, …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
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A Systematic Review on Leukemia Detection and Classification Techniques Using Gene Expression
Abstract: Early diagnosis of genetic diseases is crucial for effective treatment, especially in the case of Leukemia, a type of blood cancer characterized by abnormal proliferation of white blood cells. This paper presents a systematic review of recent computational techniques for the detection and classification of Leukemia using gene expression data obtained from DNA microarray analysis. The study explores diverse methodologies including machine learning (ML), deep learning (DL), and bio-inspired algorithms …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Revolutionizing Blood Cancer Treatment: Emerging Therapies and Future Perspectives
Abstract: Blood cancer inclusive of leukemia, lymphoma and multiple myeloma poses a significant threat in the world today because of its multifactorial process and its non-amenable to standard therapies. Some of such approaches are immunotherapy, gene-editing technology and targeted small molecule inhibitors that have altered the nature of treatments. CAR T cell therapy is a molecular targeted therapy for cancers and several clinical studies have reported a huge success. Also, the …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 3, Issue 2, 2025 Read article
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Possible Histological Changes in the pancreas of Female Albino Rats for Prolonged Administration of Aspartame
Abstract: Aspartame sweetener was noted to be inducing histopathological changes on the pancreatic tissue of female albino rats so this study defined the aims and objectives properly. Biometry did use materials from the animal facility of the Department of Biology College of Science, University of Kufa. The study was carried out over the duration of two months where thirty male rats aged between 15 to 20 weeks with body weight of …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 1, 2025 · pp. 15–21 Read article
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In-silico Approach of Few Selected Phytoconstituents on Newer Cancer Targets
Abstract: Background: Cancer’s high death rates are mainly due to, drug resistance and unmet medical demands. It necessitates novel anticancer medications. AI tools aid in efficient and faster drug discovery by analyzing data, modeling processes and optimizing pipeline stages. Aim: The aim of this present study is to evaluate phytoconstituents against novel and newer cancer targets. Methodology: The ligands Daidzein, Resveratrol and Genistein were targeted against the Glutamate dehydrogenase (PDB ID …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 3, 2024 · pp. 12–17 Read article
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Epstein-Barr virus A Review
Abstract: The unravelling of the molecular pathogenesis of malignancy that had its beginnings in the last third of the twentieth century was, in many ways, sparked by the discovery of virus-associated tumors and oncogenic viruses. Epstein Barr virus (EBV) and other viruses that soon followed were not only exciting stories in themselves but provided models with starting points and outcomes, which, since they were specific, could be dissected and generalized. In …
Published in Research and Reviews : A Journal of Immunology · Vol. 1, Issue 1-3, 2011 · pp. 10–15 Read article
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Physiotherapy Service and Its Impact on the Quality of Life in Breast Cancer Patients
Abstract: The study is based on the physiotherapy interventions in the breast cancer patients in North-east India based on the samples, population studied and treatment plans in Dr. B. Barooah Cancer Institute, Guwahati, Assam. The main objective of the study was to make the people of India especially north-east India to be aware regarding the breast cancer and promotion of importance and rules of physiotherapy treatment in the breast cancer rehabilitation …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 3, Issue 2, 2014 · pp. 8–10 Read article
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Sentinel Node Mapping in Endometrial Cancer with Radioactive Colloid Injection: A Feasibility Study
Abstract: Role of lymphadenectomy in endometrial cancer is a much-debated one. Sentinel node mapping procedure attempts to minimize the morbidity of lymphadenectomy while providing the required prognostic information. In this study, we are attempting to detect the feasibility of SLN detection in early endometrial cancer by using radioactive technetium colloid injection. This is a prospective non-randomized single-institution study where patients with apparently early endometrial cancer without enlarged lymph nodes underwent preoperative …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 4, Issue 2, 2015 · pp. 13–16 Read article
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Management of Axilla in Breast Cancer: Reducing Morbidity of Axillary Dissection
Abstract: The main role of axillary dissection for breast cancer is in deciding the nature of adjuvant therapy. Its role in improving overall survival is still not proven. Lymphedema is the most dreaded morbidity of axillary dissection. While sentinel node biopsy may help reduce this considerably, this is possibly more applicable in countries that have a regular screening program and plenty of screen-detected cancers. In India, we get most patients with …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 1, Issue 1, 2012 · pp. 1–5 Read article