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76 articles for “Genetic Mechanisms”
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AI-Driven Multi-Objective Optimization of Conductive Polymer Composites for High-Performance Flexible Electronics
Abstract: The development of conductive polymer composites (CPCs) is critical for advancing flexible and wearable electronic technologies. However, the conventional trial-and-error approach to material formulation is time-consuming and often inefficient due to the high-dimensional nature of the design space. This study introduces a novel AI-driven framework that integrates machine learning (ML) with multi-objective optimization to accelerate the discovery of high-performance CPCs. A dataset of 1,000 experimentally reported formulations was compiled, capturing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 734–745 Read article
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Valorization of Fruit and Vegetable Wastes for CA Production: A Comprehensive Review with Emphasis on Aspergillus niger Bioprocessing and Future Prospects
Abstract: Citric Acid (CA) is a multifunctional organic acid with diverse industrial applications, recently gaining prominence in polymer and composite science as a green crosslinker, compatibilizer, and functional additive. Conventionally produced through submerged fermentation of refined sugars by Aspergillus niger, industrial CA production faces sustainability challenges due to reliance on food-grade substrates. This review highlights emerging strategies for CA biosynthesis from vegetable and fruit processing residues—including cucumber peels, broccoli stalks, spinach …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 807–822 Read article
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Drug Resistance in Targeted Cancer Treatment: Clinical Difficulties, Molecular Mechanisms, and Emerging Strategies
Abstract: Targeted cancer therapy, which selectively inhibits the molecular mechanisms responsible for tumor growth and development, has revolutionized modern oncology. Targeted therapies have lower systemic toxicity and better therapeutic efficacy when compared to traditional chemotherapy. However, the emergence of medication resistance often limits the long-term efficacy of these treatments, ultimately resulting in treatment failure and disease progression. Drug resistance develops through a number of intricate biological processes and can be innate …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 130–138 Read article
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Virulence Factors in pathogens :mechanisms of infection & disease progression
Abstract: Pathogens, like bacteria, viruses, fungi, and parasites, have evolved specialized tools – known as virulence factors – that help them infect hosts, escape the immune system, and cause disease. These factors play a key role in determining how severe an infection becomes, how quickly it spreads, and how the body responds. Some pathogens use adhesins to stick to host cells, while others produce toxins that damage tissues or disrupt normal …
Published in International Journal of Pathogens · Vol. 2, Issue 1, 2025 · pp. 6–11 Read article
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A Comprehensive Review On Panic Disorders
Abstract: Panic disorder is a prevalent mental health condition characterized by sudden, recurring episodes of intense fear accompanied by physical symptoms. It is twice as likely to affect women and may have a genetic predisposition. This disorder stems from an exaggerated response of the body's survival mechanisms and hormones, impacting manifestations like agoraphobia. Additionally, it is associated with significant psychiatric comorbidity and impaired functioning in various roles. Recent research has delved …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 1, 2024 · pp. 53–59 Read article
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Multifactorial Diseases Becoming the Epigenetic Factor for the Genz
Abstract: This comprehensive paper investigates the complex interplay between multifactorial diseases, particularly obesity and cardiovascular disease (CVD), and their relationship with epigenetic mechanisms, highlighting the transgenerational implications of these interactions. The multifaceted nature of obesity and CVD, involving genetic predisposition, environmental influences, and epigenetic modifications, underscores the intricate pathways contributing to disease susceptibility and progression. Drawing upon a synthesis of diverse research findings, the paper elucidates the critical role of genetic …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 16–22 Read article
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A Decade of Viral Evolution (2015–2025): Emergence, Mutations, and Implications for Global Health
Abstract: Over the past decade (2015-2025), viral evolution has profoundly reshaped the global health landscape, challenging healthcare systems, diagnostic tools, therapeutic strategies, and vaccine efficacy. This review comprehensively analyzes the evolutionary trajectories of major human and zoonotic viruses, with a focus on pandemic-prone, drug-resistant, and emerging pathogens. Viral evolution is driven by diverse molecular mechanisms including high mutation rates, recombination, reassortment, host immune pressure, and antiviral interventions, leading to genetic diversification, …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 31–40 Read article
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Integrating Genetic Algorithms with Lean Manufacturing for Enhanced Production Efficiency
Abstract: Lean manufacturing is a well-established philosophy focusing on the systematic reduction of waste and the ongoing development of value supplied to the customer. It emphasizes efficiency, quality, and adaptability through ideas such as just-in-time production, continuous improvement (Kaizen), and value stream optimization. However, the increased complexity of modern production systems, driven by global rivalry, product variety, and rapid technology innovation, has shown the limitations of classic lean tools in achieving …
Published in Journal of Production Research & Management · Vol. 15, Issue 3, 2025 · pp. 38–43 Read article
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REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, pharmacoepigenetics integrates genetic, environmental, and lifestyle factors to explain interindividual differences in drug efficacy, toxicity, and resistance. Key epigenetic mechanisms including DNA methylation, histone modifications, non-coding RNAs, and RNA methylation play critical roles in regulating drug metabolism and therapeutic outcomes. …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Progression of Health and Wellness: Artificial Intelligence (AI) and Deep Learning (DL) for Precision Medicines
Abstract: Deep learning and artificial intelligence in the field of precision medicine is revolutionizing healthcare to make personalized therapeutic approaches desirable based on the unique characteristics of the patient. AI technologies improve diagnostic accuracy by analyzing medical data, spotting patterns and anomalies that human experts may miss. AI-driven models are instrumental in precision medicine, where they can predict patient response to therapies to tailor treatment plans, enhancing outcomes and reducing adverse …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 2, 2025 · pp. 1–5 Read article
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Examining the Role of Synthetic Biology in Cellular Restoration Mechanisms
Abstract: Synthetic biology has emerged as a transformative field with the potential to revolutionize cellular repair mechanisms, offering innovative solutions to repair damaged DNA, stabilize proteins, regenerate tissues, and treat a wide range of diseases. By combining principles from genetic engineering, biotechnology, and computational biology, synthetic biology enables the design of cellular systems capable of performing functions that repair cellular damage and restore normal cellular processes. This article explores the application …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 19–29 Read article
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Pathophysiology Reimagined: Integrating Systems Biology and AI for Disease Understanding
Abstract: Pathophysiology, the study of disease mechanisms at molecular, cellular, and systemic levels, has traditionally relied on reductionist approaches that often fail to capture the complex, dynamic, and interconnected nature of biological systems. Diseases such as cancer, neurodegenerative disorders, and infectious diseases arise from intricate interactions among genetic, epigenetic, metabolic, and environmental factors, necessitating integrative, data-driven methodologies for a deeper understanding. Systems biology has emerged as a powerful approach by leveraging …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 63–71 Read article
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A Comprehensive Review on Impact of Natural Selection Leading to Convergence
Abstract: This tale explores the complex relationship between genetic creativity, adaptation and common ecological problems that is arranged by the master sculptor, natural selection. Convergence reveals the adaptive genius that runs throughout the structure of evolution and is an acknowledgment to the continued power of natural selection. This journey aims to solve the enigma of convergent evolution. Natural selection has been influencing every link in the complex web of life on …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 1, 2024 · pp. 1–7 Read article
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FDA Drug Approvals 2024: A Comprehensive Review
Abstract: The year 2024 has been pivotal for the pharmaceutical industry, with the U.S. Food and Drug Administration (FDA) granting approval to a diverse array of new drugs. These approvals highlight significant strides in therapeutic innovation, targeting a spectrum of diseases from rare genetic disorders to prevalent chronic conditions. This article provides a detailed examination of the FDA-approved drugs of 2024, focusing on their therapeutic indications, mechanisms of action, and the …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 1, 2025 · pp. 28–46 Read article
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Bacteriophages- A New Frontier in Medicine
Abstract: Bacteriophages, or phages, are viruses that specifically target and infect bacteria, offering an innovative alternative to traditional antibiotic treatments, especially in the face of rising antibiotic resistance. The resurgence of phage therapy has been driven by the increasing prevalence of multidrug-resistant bacterial strains and the slowdown in the development of new antibiotics. Phages, unlike antibiotics, target specific bacterial strains, reducing the impact on the natural microbiota and potentially offering a …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 31–35 Read article
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Systematic Review of Application of Nature-Inspired Algorithms for Resource Optimization in Multi-Programmed Operating Systems
Abstract: Multi-programmed operating systems are increasingly confronted with complex challenges in efficiently managing system resources, primarily due to the need to handle numerous concurrent processes with diverse and often conflicting resource demands. As these systems evolve, ensuring optimal performance across various dimensions, such as CPU scheduling, memory allocation, and load balancing, has become crucial. In this context, nature-inspired algorithms have emerged as promising solutions for enhancing resource optimization. These algorithms, which …
Published in Journal of Operating Systems Development & Trends · Vol. 12, Issue 2, 2025 · pp. 08–14 Read article
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Epidermolysis Bullosa and Its Role in Cervical Cancer: An Overview
Abstract: Epidermolysis Bullosa is a group of uncommon genetic disorders that primarily affect the skin and mucous membranes. It is marked by severe skin fragility and the formation of blisters even after minor trauma. Traditionally, the focus of Epidermolysis Bullosa research has been on its dermatological manifestations, which include recurrent blistering, scarring, and the potential for infections due to the compromised skin barrier. However, recent advancements in Epidermolysis Bullosa research have …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 2, 2024 · pp. 14–18 Read article
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Nutritional Status, Bioactive Properties & Therapeutic Efficacy of Omega-3 Polyunsaturated Fatty Acids Obtained by Green Synthetic Routes
Abstract: Polyunsaturated fatty acids (PUFAs), particularly omega-3 (n-3) fatty acids like eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are crucial for human health. They support structural brain development, visual acuity, and cardiovascular function, while also exhibiting potent anti-inflammatory, antioxidant, and antimicrobial properties. Historically, marine fish oil has been the primary dietary source of these essential fatty acids. However, escalating concerns regarding ecological environmental impacts, the oceanic bioaccumulation of heavy metal contaminants, …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Nanomedicine in Combination with Artificial Intelligence (AI): Transforming Cancer Treatment
Abstract: The convergence of nanomedicine and artificial intelligence (AI) holds transformative potential for advancing cancer treatment, particularly in liver cancer. Nanomedicine enables the development of targeted drug delivery systems, enhanced imaging modalities, and precise therapeutic interventions, while AI facilitates data-driven decision-making, personalized treatment plans, and predictive analytics. This synergistic approach can significantly improve the diagnosis, treatment, and monitoring of liver cancer by optimizing the use of nanoparticle-based therapies. AI-powered algorithms can …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 27–30 Read article
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A Review on Solar Multilevel Inverter for the Production of Free Energy Due to the Structure with Long-life Feature
Abstract: Multilevel inverters play a major role in medium voltage, high power and renewable applications. It is also used in certain applications where high switching frequency, and high output voltage gain are required. The switching transient period of a MOSFET should be minimal because a high dv/dt rate could result in permanent damage to the MOSFET. The harmonics present could cause many problems and so it has to be minimized. The …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 13–18 Read article