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55 articles for “Chromatography”
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Determination of Compatibility of Polymer Systems and Study of Chemical Properties of their Mixtures
Abstract: We have obtained mechanical strength of materials as a result not by synthesizing new polymers, but by using industrial polymers. We have developed a technology for obtaining new composite materials based on industrial multi-tonnage polymers of high-strength polyethylene (HSPE), polyvinyl chloride (PVC), polyurethane thermoplastic elastomer (DUTEP), butyl rubber (BR), chlorocarboxylate polyethylene (CCPE), ethylene propylene rubber (EPR). To obtain a composition from these polymers, their mixture compatibility was first determined using …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 17–29 Read article
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Domino Reaction for the Synthesis of Nitroolefin Heterocyclic Compound Via Thiazole Formation Followed by Claisen Rearrangement
Abstract: The Baylis-Hillman adducts derived from nitroolefins have been conveniently transformed into Claisen rearrangement. These substances, which include benzothiazole moiety, are very biologically reactive substances. This novel nitro derivative of 2-((E)-2-nitro-3-phenylallyloxy)-3-ethoxybenzaldehyde was simply treated with mole percentage of 2-(2-(2-aminophenyl) disulfanyl) benzenamine in melt reactive condition. Hence this novel 2-(benzo[d]thiazol-2-yl)-6-ethoxy-4-((E)-2-nitro-3-phenylallyl)phenol core unit compounds was very intrusting and new opportunities for the preparation of closely related to the different [3,3] sigmatropic rearrangements related …
Published in Journal of Modern Chemistry & Chemical Technology Read article
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Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids
Abstract: The major goal of this study is to extract, isolate, and characterize curcumin-I, a component of curcuminoids. Turmeric, or Curcuma longa Linn., plays a significant role in Ayurvedic medicine. Turmeric, or Curcuma longa Linn, is the popular name for this plant. An array of chemicals with biological activity may be more easily extracted with the help of this seasoning. Some of the compounds at play include curcuminoids and turmerone, although …
Published in Journal of Polymer & Composites Read article
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Application of pET28a Vector for the Over Expression of Recombinant Human Tim23 Protein in E. coli and its Validation by Immunoblotting
Abstract: This study aimed to produce recombinant human Tim23 protein by molecular cloning, expression, and purification. Amplification of human TIM23 was carried out by polymerase chain reaction (PCR) and cloned into DH5α cells. The pET28a-human TIM23 was transformed into BL21DE3 and expressed the gene by IPTG induction. Recombinant pure human Tim23 antigen was prepared, and injected into rabbits and polyclonal antibodies were raised, which was confirmed by western blotting. The transformed …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 1, 2024 · pp. 32–44 Read article
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Advancements in Method Development and Validation for Levocetirizine: A Comprehensive Review
Abstract: This review article delves into the intricate realm of concurrent estimation of multiple compounds, with a specific emphasis on Levocetirizine and its related substances. It looks into how to improve analytical process specificity by using reverse phase high-performance liquid chromatography (RP-HPLC) in conjunction with UV detection. The study meticulously explores the intricacies of method development and validation, offering invaluable insights into the realms of precision and accuracy within pharmaceutical analysis. …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 15–27 Read article
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A Comprehensive Exploration of Method Validation and Development in Pharmaceutical Analysis: Focus on Vortioxetine Analysis
Abstract: The pharmaceutical industry relies on rigorous method validation to ensure the accuracy, precision, and reliability of analytical techniques employed in drug testing and quality control. This comprehensive exploration delves into the validation parameters and guidelines essential for method validation, emphasizing accuracy, precision, linearity, detection and quantitation limits, specificity, range, robustness, and ruggedness. Validation plays a pivotal role in guaranteeing high-quality products, adhering to good manufacturing practices (GMP), and optimizing manufacturing …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 1, 2024 · pp. 46–52 Read article
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Advances in Analytical Techniques for Water Quality Assessment
Abstract: Assessing the quality of water is essential for preserving ecological balance and public health. This study evaluates new developments in analytical methods that are meant to improve the accuracy, effectiveness, and reach of water quality monitoring. While fundamental, conventional procedures like spectrophotometry and chromatography have drawbacks in terms of sensitivity and real-time capability. By allowing quick and precise pollutant and contaminant identification, emerging technologies such as sensor networks, remote sensing, …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 2, Issue 1, 2024 · pp. 1–7 Read article
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Extraction and Compound Analysis of Bauhinia acuminata: Soxhlet Method and Identification
Abstract: In the present study, the extraction and compound analysis of Bauhinia acuminata using the Soxhlet method, coupled with identification techniques, were conducted. Bauhinia acuminata L., a member of the Leguminosae (Fabaceae) family in the Caesalpinioideae subfamily, is a shrub usually reaching a height of around 3 m. It is native to tropical Southeast Asia and commonly found in the tropical regions of India and China. Primarily grown for ornamental purposes, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 18–23 Read article
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Toxicology-Focused Development and Validation of an RP-HPLC Technique for Quantifying Bempefoic Acid and Rosuvastatin in a Fixed-Dose Combination
Abstract: A straightforward, precise method was developed to simultaneously assess Bempedoic acid and Rosuvastatin in both bulk and tablet forms. Utilizing a DIKMA Spursil C18 column (4.6 mm x 250 mm, 3.0 μm), chromatography was conducted with a mobile phase comprising 30% phosphate buffer and 70% acetonitrile, flowing at 1 ml/min. Operating at ambient temperature, the optimized wavelength for detection was set at 240 nm, revealing retention times of 4.418 min …
Published in Research and Reviews: A Journal of Toxicology · Vol. 14, Issue 2, 2024 · pp. 1–9 Read article
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Optimisation of Biodiesel synthesis process from various edible oils using KOH and NaOH as homogeneous catalysts
Abstract: In the present experimental study, an optimization of biodiesel production from different kinds of edible oils (Palm oil, Cotton-seed oil and Sunflower oil) using KOH & NaOH as homogenous catalyst has been investigated by one step transesterification method. The research study was conducted into two parts. In the first experimental study, different types of edible oils (Sunflower oil, Cottonseed oil and Palm oil) have been optimised using KOH and NaOH …
Published in Emerging Trends in Chemical Engineering · Vol. 11, Issue 2, 2024 · pp. 69–77 Read article
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Bioremediation Potential: Discovering Naphthalene-Degrading Microbes in Iraqi Contaminated Soil
Abstract: A polycyclic aromatic hydrocarbon, napthalene is an environmental contaminant with a slow rate of disintegration. Biological treatment by microbes present in contaminated places is the most important of the several approaches applied to remove it from the environment. At depths of 5 to 10 cm, soil samples were collected from areas polluted by oil near the Al-Dora and Sheikh Omar refineries. Nutrient agar was cultured with 0.1 ml of each …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 32–41 Read article
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Characterization Of Senna Occidentalis (Link.) Seed Extract
Abstract: Senna occidentalis (L.) Link commonly known as "coffee senna" or majamfari/rai dore in Hausa is a plant with a long history of traditional and medicinal uses against diseases such as inflammation, pains, and diabetes. This study presents characterization of the bioactive compounds of the seed extracts. Physicochemical analysis of seed powder was carried out following standard procedures. Qualitative phyto-chemical contents were determined for the presence and absence of major metabolites. …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 3, 2024 · pp. 13–22 Read article
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Study on Extraction and Purification of Phytochemicals from Eichhornia Crassipes Leaves
Abstract: Eichhornia crassipes is an aquatic plant that belongs to Pontederiaceae family. It is commonly known as water hyacinth. This annoying plant has been a recurring issue that should have been managed. In comparison to other natural plants and fibers, the seeds of these plants may survive up to 28 years at the water’s surface and have developed extremely quick growth properties. The water hyacinth is regarded as the world’s most …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 3, 2024 · pp. 24–28 Read article
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Inclusion of Silver Ions into Modified Cellulosic Fabrics for Durable and Improved Antibacterial Activity
Abstract: Silver ions were added to β-cyclodextrin-grafted organic cotton to create antibacterial fabrics that are more effective and long-lasting. In the presence of sodium hypophosphite, citric acid was used as a cross-linker to graft β-cyclodextrin onto the fabric, cementing the structure for ten minutes at 150°C. The presence of silver ions on the grafted fabric was verified by UV-visible and FTIR spectral studies of β-cyclodextrin, β-cyclodextrin-grafted fabric, ungrafted fabric, silver ions, …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 11, Issue 3, 2024 · pp. 39–52 Read article
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Production of n-Butanol from Biomass by Two Step Fermentation Process Using Staphylococcus Sciuri
Abstract: This study explores the sustainable production of n-butanol from wheat husk through a two-step bioconversion process. Wheat husk, an abundant agricultural residue, was first fermented into butyric acid using Bacillus subtilis. The resultant butyric acid was then converted into n-butanol using Staphylococcus sciuri. The process leverages biological fermentation to create value-added chemicals from lignocellulosic biomass, offering an eco-friendly alternative to petrochemical methods. Two steps fermentation process were carried to increase …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 18–31 Read article
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Excoecaria agallocha Extract from Leaves Encounters Antifungal, Antibacterial, and Cytotoxic Activity – In Vitro Studies
Abstract: Mangroves contain a wide range of bioactive substances, certain of and these have been used as solutions for a variation of conditions for thousands of years. Excoecaria agallocha leaf application components have been extracted in the presence of organic solvents along with water-based with a Soxhlet apparatus and antibacterial research properties employing diffusion agar well assays towards nine different kinds of culture infectious agents, six clinical trials isolated compounds, as …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 1–7 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Authentication of a Rapid RP-HPLC technique for Quantification of Remogliflozin and Metformin in Medicinal Formulations
Abstract: A new, precise, and stability-assessing advanced liquid chromatography (HPLC) technique for simultaneous quantification of Remogliflozin and Metformin in fixed dose pharmaceutical formulations was designed and verified. Optimization of the technique was carried out on flowing phase composed of ethanenitrile and buffer, under isocratic conditions, the resolution of peak being sharp with retention times of 3.24 min and 4.89 min for Remogliflozin and Metformin, respectively. Technology suitability was confirmed by the …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 70–77 Read article
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Recent Advances in Quality Control and Quality Assurance: Enhancing Pharmaceutical Product Integrity and Compliance
Abstract: The pharmaceutical industry is undergoing a paradigm shift driven by stringent regulatory expectations and the demand for high-quality, safe, and efficacious drug products. Quality Control (QC) and Quality Assurance (QA) serve as the two foundational pillars that ensure pharmaceutical integrity from raw material acquisition through to product release. Traditional QC and QA practices, while effective, have been challenged by complex formulations, biologics, and personalized medicine, requiring innovative methodologies and technologies. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 54–62 Read article
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Optimizing Chromatographic Techniques for Comprehensive Paraben Analysis to Enhance Safety in Consumer Products
Abstract: Parabens (PBs), such as methylparaben (MePB), ethylparaben (EtPB), propylparaben (PrPB), and butylparaben (BuPB), are widely used as preservatives in pharmaceuticals, food, and personal care products due to their antibacterial properties. However, there are growing worries about their potential to disrupt hormonal functions, which has led to stricter regulations. This study focuses on creating a robust high-performance liquid chromatography (HPLC) method for quickly measuring all four parabens in consumer goods. We …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 228–243 Read article